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Hepatology International

Hepatology International is a peer-reviewed journal dedicated to research and patient care issues in hepatology. It focuses on contemporary clinical and basic science related issues in adult and pediatric hepatobiliary and allied sciences, and publishes original research articles, editorials, reviews, and consensus guidelines for diagnosis and treatment of liver diseases. The journal emphasizes new and emerging technologies, innovations, and future trends in liver and biliary disorders.

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Impact Factor 6.1
Quartile Q1
Open Access Type Hybrid
ISSN 1936-0533
eISSN 1936-0541
Invitation Only Yes
Cost Range Open access APC: £3290.00 GBP / $5290.00 USD / €4090.00 EUR; subscription publishing: no APC charges apply.

Submission Instructions

Hepatology International is an invitation-only journal. Submissions are accepted by invitation from the editorial board only. The following article types are accepted:

Original Article

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required for Original Articles. Abstract must be structured and limited to 250 words. Abstract must be structured.
Manuscript Manuscript text must not exceed 4000 words including references. Manuscript must be organized into Introduction, Materials and Methods, Results, and Discussion. Manuscript must include 10 keywords, a concept diagram or graphical abstract immediately after the abstract, and declarations just before the reference section.
References Reference list must not exceed 30 references. References must follow the U.S. National Library of Medicine style as in Index Medicus. References must be numbered in order of first appearance in the text, with repeated citations using the original number.
Figures & Tables Original Articles may include up to 6 tables, flow diagrams, colored figures, text boxes, or other illustrations. Figures should be submitted within the body of the text, with large figures submitted separately only if file size causes upload problems. The graphical abstract must be a single-panel high-resolution image of at least 300 dpi, preferably in .tif or .jpg format, using RGB color and Arial 12–16 pt font.
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Review Article

Cover Letter Submission must be approved by all co-authors and by the responsible authorities at the institute where the work was carried out.
Abstract An abstract is required for Review Articles. The abstract must be limited to 250 words. The abstract must be unstructured.
Manuscript The text must not exceed 5000 words including references. The main text must be organized into an introductory section followed by Discussion, Conclusion, and Perspective. Review Articles must include 10 keywords and declarations just before the reference section.
References The reference list must not exceed 100 references. References must follow the U.S. National Library of Medicine style as in Index Medicus. References must be numbered in order of first appearance in the text and reused with the same number on subsequent citation.
Figures & Tables Review Articles must include at least 4 colored figures and at least 4 tables, with no more than 8 total tables, flow diagrams, colored figures, text boxes, or other illustrations. Figures should be submitted within the body of the text, with large figures submitted separately only if file size causes upload problems. Each table and figure must be numbered in Arabic numerals and cited in the text in consecutive numerical order.
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Mini Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required and must be structured. Abstract must not exceed 150 words. Abstract must be structured.
Manuscript Text must not exceed 2500 words excluding references. Declarations must be included just before the reference section. Mini Reviews must include 10 keywords.
References Reference list must not exceed 30 references. References must follow the U.S. National Library of Medicine style used in Index Medicus. References must be numbered in order of first appearance in the text, and repeated citations must use the original reference number.
Figures & Tables Mini Reviews may include up to 4 tables, flow diagrams, colored figures, text boxes, or other illustrations, and should include at least 2 colored figures and at least 2 tables or algorithms. Figures should be submitted within the body of the text, with large figures submitted separately only if file size causes upload problems. Each table and figure must be numbered in Arabic numerals, cited in consecutive numerical order, and accompanied by a caption, with figure captions included in the manuscript text file rather than in the figure file.
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Consensus

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Consensus manuscripts must not exceed 2000 words. Manuscripts should include funding information and, as appropriate, financial or non-financial interests, ethics committee approval, informed consent, and animal welfare statements.
References Consensus manuscripts must not include more than 9 references. References must follow the U.S. National Library of Medicine style as in Index Medicus. References must be numbered in order of first appearance in the text and reused with the same number for subsequent citations.
Figures & Tables Figures should be submitted within the body of the text, with large figures uploaded separately only if file size causes problems. Each table and figure must be numbered with Arabic numerals and cited in consecutive numerical order, and each figure must have a concise caption included in the manuscript text file.
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Letter To Editor

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not be included.
Manuscript Text must not exceed 500 words excluding references. Keywords must not be included, and one figure must be included.
References Reference list must not exceed 5 references. References must follow the U.S. National Library of Medicine style as in Index Medicus. References must be numbered in order of first appearance in the text, and repeated citations must use the original reference number.
Figures & Tables Submission must include one figure. Figures should be submitted within the body of the text, with large figures submitted separately only if file size causes upload problems. Each figure must be numbered with Arabic numerals, cited in consecutive numerical order, and accompanied by a concise caption included in the manuscript text file rather than in the figure file.
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Recent Publications

Clinical and pathological significance of serum anti-PD-1 autoantibodies in acute-onset and chronic autoimmune hepatitis

Takashi Oda, Akinobu Takaki, Kenichi Harada, Teruko Arinaga-Hino, Masanori Abe, Takeshi Matsui, Atsushi Takahashi, Hiromasa Ohira, Yoshiyuki Suzuki, Nobuhiro Nakamoto, Atsushi Tanaka, Kazuyuki Matsumoto, Jinpeng Li, Nozomi Miyake, Masahiko Sue, Takuya Adachi, Yasuto Takeuchi, Hideki Onishi, Miwa Kawanaka, Motoyuki Otsuka

10.1007/s12072-026-11152-x
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Circulating fibronectin levels are linked to liver function, matrix remodeling, and hemostatic complications in advanced chronic liver disease

Georg Kramer, Irina Andreea Lie-Ungurean, Benedikt Silvester Hofer, Lukas Hartl, Mathias Jachs, Lorenz Balcar, Georg Semmler, Christian Sebesta, Paul Thöne, Marlene Hintersteininger, Paula Höfinger, Rodrig Marculescu, Thomas Perkmann, Philipp Schwabl, Michael Trauner, Mattias Mandorfer, Thomas Reiberger, Benedikt Simbrunner

10.1007/s12072-026-11140-1
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The Global ACLF Consensus : the ‘Istanbul Document’

Anand V. Kulkarni, Ashok Choudhury, Vinod Arora, Abdul Kadir Dokmeci, Abraham Koshy, Ahmet Gurakar, Ajay Duseja, Akash Roy, Akash Shukla, Aleksander Krag, Alfred Wei Chieh Kow, Ananta Shrestha, Apichat Kaewdech, Ashish Goel, Ashish Kumar, Ashwani K. Singal, Aung Hlaing Bwa, Chanunta Hongthanakorn, Cosmas Rinaldi Adithya Lesmana, Daniel Huang, Darrell Crawford, Debbie Shawcross, Deniz Balchi, Dhiraj Agrawal, Diana A. Payawal, Do Seon Song, Dong Joon Kim, Fernando Bessone, George K. Lau, Giacomo Germani, Girish Kumar Pati, Grace L. Su, Guan-Huei Lee, Gupse Adali, Gyongyi Szabo, Hasmik Ghazinian, Jacob George, James Fung, Jasmohan Bajaj, P. Javed, Jidong Jia, Jimmy Che-To Lai, Jin Jun Chen, Jonel Trebicka, Jun Li, Kavish Patidar, Kemal Fariz Kalista, Ken Liu, Kessarin Thanapirom, Lai Wei, M. Golam Azam, Madhumita Premkumar, Madunil Niriella, Manasa Alla, Mangesh Pagadala, Manoj Kumar, Manuel Mendizabal, Mario Guimaraes Pessoa, Mark Dhinesh Muthiah, Masao Omata, Mazen Noureddin, Md. Fazal Karim, Mithun Sharma, Mohamed Alboraie, Mohamed Elbasiony, Murat Harputluoglu, Narendra Singh Choudhary, Nazia Selzner, Necati Ormeci, Nelia Hernandez, Nipun Verma, Paolo Angeli, Phunchai Charatcharoenwitthaya, Prabir Maji, Pravin Rathi, R. K. Dhiman, Rahul Kumar, Rakhi Maiwall, Ramazan Idilman, Richard Moreau, Rino A. Gani, Rosmawati Mohamed, S. S. Hamid, Sanjeev Sachdeva, Senamjit Kaur, Shahinul Alam, Soe Thiha Maung, Soek-Siam Tan, T. R. Sowmya, K. C. Sudhamshu, Sumana Ramachandra, Sunil Kumar Dadhich, Sunil Taneja, Suprabhat Giri, Surender Singh, Tao Chen, Tarana Gupta, Tushar Madke, V. M. Dayal, Venishetty Shantan, Viniyendra Pamecha, Wong Yu Jun, Xiaolong Qi, Yoon Jun Kim, Zaigham Abbas, Zobair M. Younossi, Shiv Kumar Sarin

10.1007/s12072-026-11136-x
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Dynamic changes in controlled attenuation parameter (CAP) improve prognostic prediction for CHB patients with significant fibrosis and cirrhosis

Xiaowei Ai, Mengyang Zhang, Shuyan Chen, Xinyu Zhao, Jialing Zhou, Tongtong Meng, Bingqiong Wang, Chenglin Sun, Xiao Han, Yankun Gao, Xiaoning Wu, Hong You, Yameng Sun

10.1007/s12072-026-11145-w
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How to apply artificial intelligence (AI) to facilitate and enhance MASH trials

Daniel Yan Zheng Lim, Wei Qiang Leow, Daniela S. Allende, Wai Kay Seto, Terry Cheuk-Fung Yip, George Boon Bee Goh

10.1007/s12072-026-11150-z
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Frequently asked questions

How long does it take to publish?

Articles are published online after receipt of the corrected proofs.

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Is a cover letter required?

A submission letter is used when suggesting reviewers and when disclosing unpublished material included in the manuscript.

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What are the publication costs?

Open access APC: £3290.00 GBP / $5290.00 USD / €4090.00 EUR, subject to VAT or local taxes where applicable. Subscription publishing has no APC charges.

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Research Topics

Liver Disease Diagnosis and Treatment Liver Disease and Transplantation Hepatitis C virus research Hepatitis B Virus Studies Hepatocellular Carcinoma Treatment and Prognosis Organ Transplantation Techniques and Outcomes Hepatitis Viruses Studies and Epidemiology Liver Diseases and Immunity Liver physiology and pathology Cholangiocarcinoma and Gallbladder Cancer Studies Alcohol Consumption and Health Effects Drug-Induced Hepatotoxicity and Protection Diabetes, Cardiovascular Risks, and Lipoproteins Cancer Immunotherapy and Biomarkers HIV/AIDS drug development and treatment Gallbladder and Bile Duct Disorders Diet, Metabolism, and Disease Pediatric Hepatobiliary Diseases and Treatments Ferroptosis and cancer prognosis Radiomics and Machine Learning in Medical Imaging Drug Transport and Resistance Mechanisms Nutrition and Health in Aging Inflammatory Biomarkers in Disease Prognosis Cancer, Hypoxia, and Metabolism Cancer Mechanisms and Therapy