SC

Stem Cell Research & Therapy

Stem Cell Research & Therapy focuses on translational research into stem cell therapies and serves as a platform for global debate and discussion. It emphasizes basic, translational, and clinical research and publishes articles on stem cell therapeutics and regenerative therapies, including animal models and clinical trials.

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Subject Medicine, Research & Experimental
Impact Factor 7.3
Quartile Q1
Open Access Type Open
eISSN 1757-6512
Invitation Only No
Cost Range Article processing charge: £2490.00 GBP / $3290.00 USD / €2790.00 EUR, plus VAT or local taxes where applicable.

Submission Instructions

Stem Cell Research & Therapy accepts the following article types. Click on an article type to view submission instructions.

Research

Cover Letter A cover letter is required and for Research submissions it must include any policy-related issues, competing interests, confirmation of all authors’ approval and exclusive submission, and the names of at least eight potential reviewers without conflicts of interest. The cover letter must include policy-related issues, a declaration of any potential competing interests, confirmation that all authors approved submission, confirmation that the manuscript is not published or under consideration elsewhere, and at least eight potential reviewer names with no conflicts of interest.
Abstract An abstract is required for Research manuscripts. The abstract must not exceed 350 words. The abstract must be structured. The abstract must include the headings Background, Methods, Results, and Conclusions.
Manuscript The manuscript must include Background, Methods, Results, Discussion, Conclusions, and a Declarations section with all required subheadings. Research manuscripts must include three to ten keywords, include all required Declarations subheadings even if marked 'Not applicable', and document any use of a Large Language Model in the Methods section or another suitable section if Methods is unavailable.
References References must follow Vancouver style. Only published or in-press articles, clinical trial registration records, and abstracts or items available on public e-print or preprint servers may be cited, unpublished abstracts/data and personal communications must be excluded from the reference list, and web links or URLs must be numbered and included in the reference list.
Figures & Tables Figure titles and legends must appear in the main manuscript, large tables may be placed at the end of the manuscript, overly wide tables may be uploaded as additional files, and tables must not be embedded as figures or spreadsheet files. Figures must be numbered in first-citation order and submitted as single composite files for multi-panel figures, and if cropped gels or blots appear in the main text the cropping must be evident in the legend with corresponding uncropped full-length versions included in the supplementary files.
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Review

Cover Letter A cover letter is required, and for Review submissions it must include the names of at least eight potential reviewers with no conflicts of interest. The cover letter must explain any issues relating to journal policies, declare any potential competing interests, confirm all authors approved the submission, confirm the manuscript has not been published or submitted elsewhere, include the special issue name if applicable, and list at least eight potential reviewers without conflicts of interest.
Abstract An abstract is required for Review articles. The abstract must not exceed 350 words. The abstract must be structured. The abstract must include Background, Main body of the abstract, and short Conclusion.
Manuscript Review articles should be approximately 5000 words. Review articles must include a Background section, a Main text section, a Conclusions section, and a Declarations section with the specified subsection headings. Review articles must include three to ten keywords and a Declarations section containing the subheadings Ethics approval and consent to participate, Consent for publication, Availability of data and materials, Competing interests, Funding, Authors' contributions, Acknowledgements, and Authors' information, with any irrelevant subsection labeled 'Not applicable'.
References Review articles should include 60 references. References must follow Vancouver style. Only articles, clinical trial registration records, and abstracts that are published, in press, or publicly available as e-prints or preprints may be cited; unpublished abstracts, unpublished data, and personal communications must not appear in the reference list; journal abbreviations must follow Index Medicus/MEDLINE; and web links or URLs must be numbered and included in the reference list in full with title, URL, and access date.
Figures & Tables Figure titles and legends must be provided in the main manuscript, tables larger than one page may be placed at the end of the manuscript, tables too wide for a page may be uploaded as additional files, and tables must not be embedded as figures or spreadsheet files. Figures must be numbered in the order first mentioned and multi-panel figures submitted as a single composite file, while tables must be numbered and cited in sequence using Arabic numerals.
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Correspondence

Cover Letter A cover letter is required and must include at least eight potential reviewers in the relevant field who have no conflicts of interest. The cover letter must explain any issues relating to journal policies, declare any potential competing interests, confirm all authors approved submission, confirm the manuscript is not published or under consideration elsewhere, name any special issue if applicable, and include at least eight conflict-free potential reviewers.
Abstract An abstract is required. Abstract must not exceed 250 words.
Manuscript Correspondence must be no longer than 1000 words. The manuscript may be broken into subsections with short, informative headings and must include a Declarations section. The manuscript must include three to ten keywords, a Declarations section with the specified subheadings using 'Not applicable' where relevant, a list of abbreviations if abbreviations are used, an Availability of data and materials statement, and documentation of any Large Language Model use in the Methods section or another suitable section.
References Correspondence must contain no more than 10 references. References must follow the Vancouver reference style. Web links and URLs must be assigned a reference number and included in the reference list rather than in the text.
Figures & Tables Correspondence must contain no more than one display item, including boxes, tables, or figures. Figure titles and legends must be provided in the main manuscript, while corresponding uncropped full-length gels and blots must be included in the supplementary files. Any blot cropping must be clearly evident and mentioned in the figure legend, and uncropped images must show the crop locations, be labelled as in the main text, and be placed in a single supplementary figure.
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Short Report

Cover Letter A cover letter is required. Cover letter must explain any issues relating to journal policies, declare any potential competing interests, confirm all authors approved the submission, confirm the manuscript has not been published or submitted elsewhere, include at least eight potential reviewers with no conflicts of interest, justify why the results merit publication in a shortened format, and name the special issue if applicable.
Abstract An abstract is required. Abstract must not exceed 250 words.
Manuscript Short Reports must be a maximum of 2000 words excluding references and table and figure legends. Manuscript must include a title page with full author names and institutional addresses, identify the corresponding author, present a title including the study design where appropriate, and include a Declarations heading containing Availability of data and materials, Competing interests, Funding, Authors' contributions, Acknowledgements, and any non-relevant declarations marked 'Not applicable'. Manuscript must include three to ten keywords, a list of abbreviations if abbreviations are used, specified author contributions using initials, competing interests identified using authors' initials, and an acknowledgement of any outsourced work or data not collected by the authors.
References References must follow Vancouver style. Only published or in-press articles, clinical trial registration records, abstracts, and public e-prints or preprints may be cited; unpublished abstracts, unpublished data, and personal communications must not appear in the reference list; web links must be numbered and listed as full references; and journal abbreviations must follow Index Medicus/MEDLINE.
Figures & Tables Short Reports may include no more than 4 figures and/or tables. Figure titles and legends must be provided in the main manuscript, while figures are uploaded separately and uncropped full-length gels and blots must be included in the supplementary files as a single supplementary figure. Figures and tables must be numbered in the order cited, multi-panel figures must be submitted as a single composite file, and figure legends must state that full-length blots or gels are presented in the supplementary figure.
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Recent Publications

L-DOPA enhances iRPE differentiation via Wnt signaling and improves cytotherapy for retinal degradation

Yifeng Ke, Yingxiang Zhao, Qiang Feng, Min Xue, Mingxuan Zhang, Liangzhang Tan, Xinjun Ren

10.1186/s13287-026-05074-6
View Publication

Exosome-derived LncRNAs in bone remodeling: recent advances and future directions for bone disease therapy

Shihua Zhang, Hui Wang, Chenyu Zhao, Chenyu Zhu, Xun Li, Zhi’ang Su, Jun Zou, Chong Wang, Lan Zhang, Yu Yuan, Xuewen Tian

10.1186/s13287-026-05068-4
View Publication

Construction of liver organoid models by hepatobiliary differentiation from human induced pluripotent stem cells: state of the art, challenges and improving strategies

Yi-Hang Wu, Yang Wang, Wen-Jie Zhang, Li-Li Yuan, Yan Chen

10.1186/s13287-026-05080-8
View Publication

Development of a novel GAK solution for efficient hypothermic preservation of NK cell viability and anti-tumor function

Xin Wang, Xiaolong Liu, Guangyuan Wu, Hailong Wang, Kuo Yu, Yang Liu, Hongrui Xu, Xin Sun, Zhongyao An, Linlin Zhao, Ce Shi, Mingli Huang, Zhenkun Wang

10.1186/s13287-026-05083-5
View Publication

Mechanical stretch loading of BMSCs-PLCL composite scaffolds accelerate diabetic wound healing by protecting endothelial cells and promoting angiogenesis

Zhe Liu, Congying Zhao, Haowei Zhou, Zhen Shi, Rong Huang, Lirong Xu, Junwei Su, Gaoyan Chen, Zehui Zhao, Yuqian Li, Jing Li

10.1186/s13287-026-05072-8
View Publication

Frequently asked questions

How long does it take to publish?

Submission to first decision (median): 15 days.

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Is a cover letter required?

A cover letter is required and should explain why the manuscript should be published in Stem Cell Research & Therapy, address any issues relating to journal policies, declare potential competing interests, confirm that all authors approved the submission, confirm that the manuscript has not been published or submitted elsewhere, and name the special issue if applicable. Authors may also suggest preferred and non-preferred peer reviewers in the cover letter.

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What are the publication costs?

An article processing charge applies for each accepted article. The current APC is £2490.00 GBP / $3290.00 USD / €2790.00 EUR, plus VAT or local taxes where applicable.

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Research Topics

Mesenchymal stem cell research Pluripotent Stem Cells Research Tissue Engineering and Regenerative Medicine Extracellular vesicles in disease Cancer Cells and Metastasis Wound Healing and Treatments MicroRNA in disease regulation Neurogenesis and neuroplasticity mechanisms Osteoarthritis Treatment and Mechanisms Angiogenesis and VEGF in Cancer Periodontal Regeneration and Treatments Liver physiology and pathology Reproductive Biology and Fertility Hematopoietic Stem Cell Transplantation Nerve injury and regeneration CRISPR and Genetic Engineering Neonatal Respiratory Health Research Pancreatic function and diabetes Immune cells in cancer Congenital heart defects research 3D Printing in Biomedical Research Corneal Surgery and Treatments Hair Growth and Disorders Electrospun Nanofibers in Biomedical Applications Bone and Joint Diseases

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