Overview
Submission Instructions
Recent Publications
Frequently Asked Questions
Research Topics
Looking to publish in Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration? Livewrite integrates seamlessly with Word to help you write, edit, and format faster.
Existing customer login
AL
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration publishes research on motor neuron diseases, especially ALS and cognitive decline associated with frontotemporal degeneration. It is the official journal of the World Federation of Neurology Research Group on Motor Neuron Diseases and covers topics including cognitive decline, basic science, genetics, new treatments and clinical trials, epidemiology, and clinical neurophysiology.
Looking to publish in Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration? Livewrite integrates seamlessly with Word to help you write, edit, and format faster.
Existing customer login
Subject
Clinical Neurology
Impact Factor
2.8
Quartile
Q2
Open Access Type
Closed
ISSN
2167-8421
eISSN
2167-9223
Invitation Only
No
Cost Range
Institutional online-only subscription: USD 3,081.00; print and online subscription: USD 4,504.00.
Submission Instructions
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration accepts the following article types. Click on an article type to view submission instructions.
Original Articles
Cover Letter
Cover Letter requirements are not specified.
Abstract
A structured abstract is required for Original Articles. Abstract must be 250 words. Abstract must be structured. The structured abstract must cover Objective, Methods, Results, and Conclusions, and for Original Articles it should describe the method and procedures.
Manuscript
Original Articles must not exceed 3000 words excluding the abstract and references. Manuscript should be compiled in the order of title page, abstract, keywords, main text with Introduction, Materials and methods, Results, and Discussion, acknowledgments, declaration of interest statement, references, appendices as appropriate, tables with captions, figures, and figure captions. Manuscript must include 3 to 5 keywords, a disclosure statement under the subheading “Disclosure of interest,” a statement disclosing whether and how generative AI was used, a short biographical note for each author of no more than 200 words, and a word count.
References
References must use Vancouver style. References must be numbered consecutively in order of first citation, cited in the text as digits in parentheses, and entries with more than ten authors must list the first ten followed by “et al.”.
Figures & Tables
Figures should be saved separately from the text. Tables must be supplied as editable files.
Reviews
Cover Letter
Cover Letter requirements are not specified.
Abstract
A structured abstract is required for Reviews. Abstract must be 250 words. Abstract must be structured. Abstract must cover the primary objective of the review, the reasoning behind the choice of review, the main outcomes and results, and the conclusions including implications for further research, application, or practice.
Manuscript
Reviews must not exceed 3000 words excluding the abstract and references. Manuscript should be compiled in the order title page, abstract, keywords, main text, acknowledgments, declaration of interest statement, references, appendices as appropriate, tables with captions on individual pages, figures, and figure captions as a list. Manuscript must include 3 to 5 keywords, a disclosure statement under the subheading “Disclosure of interest,” a generative AI use statement, a word count, and a short biographical note of no more than 200 words for each author.
References
Vancouver referencing style must be used. References must be numbered consecutively in order of first citation and listed using the same number for repeated citations, with in-text citations given as digits in parentheses.
Figures & Tables
Figures should be saved separately from the text. Tables must be supplied as editable files.
Non-Systematic Reviews
Cover Letter
Cover Letter requirements are not specified.
Abstract
A 150-word maximum block-style non-structured abstract is required. Abstract must not exceed 150 words. Abstract must be block-style and non-structured. Abstract should state the primary objective of the review, the reasoning behind the choice of review, the main outcomes and results, and the conclusions including implications for further research, application, or practice.
Manuscript
Manuscript should be compiled in the order of title page, abstract, keywords, main text, acknowledgments, disclosure of interest statement, references, appendices as appropriate, tables with captions, figures, and figure captions. Manuscript must include 3 to 5 keywords, a disclosure statement under the subheading “Disclosure of interest,” a generative AI use statement, a word count, and a short biographical note for each author of no more than 200 words.
References
References must use Vancouver style. References must be numbered consecutively in order of first citation and list the first ten authors followed by “et al.” when there are more than ten authors.
Figures & Tables
Figures should be saved separately from the text. Tables must be supplied as editable files and should present new information without duplicating the text.
Reports
Cover Letter
Cover Letter requirements are not specified.
Abstract
A structured abstract is required. Abstract must be 250 words. Abstract must be structured. Abstract must include the headings Objective, Methods, Results, and Conclusions in that order.
Manuscript
Reports must not exceed 3000 words, excluding the abstract and references. Manuscript should be organized in the order title page, abstract, keywords, main text with introduction, materials and methods, results, and discussion, acknowledgments, declaration of interest statement, references, appendices as appropriate, tables with captions, figures, and figure captions. Manuscript must include 3 to 5 keywords, a disclosure statement under the subheading “Disclosure of interest,” a statement disclosing whether and how generative AI was used, a word count, and a short biographical note of no more than 200 words for each author.
References
References must use Vancouver style. References must be numbered consecutively in order of first citation and cited in the text using digits in parentheses.
Figures & Tables
Figures should be saved separately from the text. Tables must be supplied as editable files.
Case Reports
Cover Letter
Cover Letter requirements are not specified.
Abstract
A non-structured block-style abstract is required for Case Reports. The abstract must not exceed 150 words. The abstract must be non-structured and presented in block style. No abstract headings are required because the abstract must be non-structured.
Manuscript
The manuscript should be approximately 750 words. The paper should be compiled in the order of title page, abstract, keywords, main text, acknowledgments, declaration of interest statement, references, appendices as appropriate, tables with captions on individual pages, figures, and figure captions as a list. The manuscript must include 3 to 5 keywords, a disclosure statement under the subheading “Disclosure of interest,” and a statement disclosing whether and how generative AI was used in the research and manuscript preparation process.
References
Case Reports must have no more than 10 references. Vancouver referencing style must be used. References must be numbered consecutively in order of first citation in the text, cited using digits in parentheses, and list the first ten authors followed by “et al.” when there are more than ten authors.
Figures & Tables
Figures should be saved separately from the text. Tables must be supplied as editable files.
Other Short Reports
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract must not exceed 250 words. Abstract must be structured. Abstract must include the headings Objective, Methods, Results, and Conclusions.
Manuscript
Manuscript should be approximately 750 words. Manuscript should be compiled in the order title page, abstract, keywords, main text with introduction, materials and methods, results, and discussion, acknowledgments, declaration of interest statement, references, appendices as appropriate, tables with captions, figures, and figure captions. Manuscript must include 3 to 5 keywords, a disclosure statement under the subheading “Disclosure of interest,” and a statement disclosing whether and how generative AI was used in the research and manuscript preparation process.
References
References must not exceed 10. Vancouver style must be used. References must be numbered consecutively in order of first citation, cited in the text using digits in parentheses, and list the first 10 authors followed by “et al.” when there are more than 10 authors.
Figures & Tables
Figures should be saved separately from the text. Tables must be supplied as editable files.
Short Reports
Cover Letter
Cover Letter requirements are not specified.
Abstract
An abstract is required. The abstract must be a block-style non-structured abstract of no more than 150 words. The abstract must be non-structured and presented in block style. Abstract headings are not required because the abstract must be non-structured.
Manuscript
The manuscript should be compiled in the order of title page, abstract, keywords, main text with introduction, materials and methods, results, and discussion, acknowledgments, declaration of interest statement, references, appendices as appropriate, tables with captions, figures, and figure captions. The manuscript must include 3 to 5 keywords, a disclosure statement under the subheading “Disclosure of interest,” and a statement disclosing whether and how generative AI was used in the research and manuscript preparation process.
References
References must use Vancouver style. References must be cited in the text with digits in parentheses and numbered consecutively in the reference list according to first citation order.
Figures & Tables
Figures should be saved separately from the text. Tables must be supplied as editable files.
Correspondence
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract requirements are not specified.
Manuscript
Correspondence should not exceed 750 words. A statement disclosing whether and how generative AI has been used in the research and manuscript preparation process must be included.
References
Vancouver referencing style must be used. References must be numbered consecutively in order of first citation in the text.
Figures & Tables
Correspondence may include 1 figure or table. Figures should be saved separately from the text.
Recent Publications
Intermuscular coherence as a candidate biomarker for primary lateral sclerosis
Naoum P. Issa, Elena Badillo-Goicoechea, Serdar Aydin, Nathan Carberry, Sean Smith, Mark A. Garret, Doreen Ho, Rachel Freedman, Kelly McCoy-Gross, Alejandra Casas, Betty Soliven, Kourosh Rezania
10.1080/21678421.2026.2699211
View Publication
Feasibility and sensitivity of a multimodal digital endpoint panel for amyotrophic lateral sclerosis: a prospective cohort study
Lianne C.M. Botman, Jordi W.J. van Unnik, Anita Beelen, Jaap N.E. Bakers, Nina D. van der Schoot, Manon A.P. Gremmen, Sybel van Helm, Leonard H. van den Berg, Ruben P.A. van Eijk
10.1080/21678421.2026.2696382
View Publication
Reduced penetrance in genetic ALS/FTD spectrum disorders: implications for genetic counseling, predictive testing and treatment
Elizabeth A. Harrington, Laynie Dratch, Tara A. Jones, Jamie C. Fong, Daniel D. Kinnamon, Jill Goldman, Wendy R. Uhlmann, Jennifer Roggenbuck
10.1080/21678421.2026.2696378
View Publication
An open-label Phase 2a study of fasudil in amyotrophic lateral sclerosis: safety and exploratory endpoints
Claudia Pena, Casey Barker, Allison N. Grossberg, Ibrahim Mian, Sabrina Williams, Thomas MacAllister, Tuan Vu, Daniel A. Linseman
10.1080/21678421.2026.2694507
View Publication
Noninvasive assessment of cardiovascular autonomic reflexes in amyotrophic lateral sclerosis: a systematic review
Sorfina Ilham Rozman, Nur Azah Hamzaid, Einly Lim, Norhamizan Hamzah
10.1080/21678421.2026.2692135
View Publication
Frequently asked questions
How long does it take to publish?
Average median timelines are tracked for submission to first decision, submission to first post-review decision, and acceptance to online publication, but no numerical values are stated.
Reformat to Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration using Livewrite PremiumIs a cover letter required?
Cover letters are discussed in a related resource.
Reformat to Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration using Livewrite PremiumWhat are the publication costs?
Institutional online-only subscription: USD 3,081.00; print and online subscription: USD 4,504.00.
Reformat to Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration using Livewrite PremiumResearch Topics
Amyotrophic Lateral Sclerosis Research
Neurogenetic and Muscular Disorders Research
Parkinson's Disease Mechanisms and Treatments
Genetic Neurodegenerative Diseases
Neurological diseases and metabolism
Prion Diseases and Protein Misfolding
Alzheimer's disease research and treatments
Cholinesterase and Neurodegenerative Diseases
Multiple Sclerosis Research Studies
Dysphagia Assessment and Management
Parkinson's Disease and Spinal Disorders
Neurological disorders and treatments
Cervical and Thoracic Myelopathy
Hereditary Neurological Disorders
Palliative Care and End-of-Life Issues
Biochemical Acid Research Studies
Intracerebral and Subarachnoid Hemorrhage Research
Fibromyalgia and Chronic Fatigue Syndrome Research
Healthcare Decision-Making and Restraints
Cerebral Palsy and Movement Disorders
Dementia and Cognitive Impairment Research
biodegradable polymer synthesis and properties
Respiratory Support and Mechanisms
Psychiatric care and mental health services
Mitochondrial Function and Pathology