Overview
Submission Instructions
Recent Publications
Frequently Asked Questions
Research Topics
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Frontiers in Bioengineering and Biotechnology publishes research exploring and advancing biological therapies, devices, and technologies to improve lives.
Looking to publish in Frontiers in Bioengineering and Biotechnology? Livewrite integrates seamlessly with Word to help you write, edit, and format faster.
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Subject
Engineering, Biomedical
Impact Factor
4.8
Quartile
Q2
Open Access Type
Open
ISSN
2296-4185
eISSN
2296-4185
Invitation Only
No
Cost Range
A-Type Articles: CHF 3,150; B-Type Articles: CHF 2,500
Submission Instructions
Frontiers in Bioengineering and Biotechnology accepts the following article types. Click on an article type to view submission instructions.
Original Research
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract is required and should be structured in a single paragraph. Abstract should be structured.
Manuscript
Manuscript must not exceed 12,000 words. Manuscript should be organized as Abstract, Introduction, Materials and Methods, Results, and Discussion, with a succinct Introduction that has no subheadings. Manuscript must include at least five and no more than eight keywords, indicate the word count and number of figures and tables on the first page, and acknowledge any generative AI use in the acknowledgements or methods section with the name, version, model, and source.
References
Citations and references must follow the journal's reference style. References must list the first six authors followed by et al., abbreviate given names to initials, include the DOI when available, and ensure every cited item appears in the reference list and every reference list item is cited in the text, figures, or tables.
Figures & Tables
Figures must be submitted individually in the order cited with captions placed at the end of the manuscript, while tables must be inserted at the end of the manuscript in editable format. All figures or images must include alternative text, each figure must be mentioned and cited in numerical order in the text, and large tables covering several pages must be published as supplementary material.
Systematic Review
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract must be structured and presented as a single paragraph.
Manuscript
Manuscript must not exceed 12,000 words. Systematic Review must clearly define the research question in terms of population, interventions, comparators, outcomes, and study designs (PICOS). Manuscript must include funding information, at least five and no more than eight keywords, and an acknowledgement or methods statement identifying any generative AI use with its name, version, model, and source.
References
References must follow the journal reference style, list the first six authors followed by et al. with DOI when available, and must not include unpublished material, submitted manuscripts, or personal communications.
Figures & Tables
Figures must be submitted individually with captions placed at the end of the manuscript, and tables must be inserted at the end of the manuscript in editable format. All figures and tables must be cited in the text, and figures with multiple panels must use labels such as (A), (B), and (C).
Review
Cover Letter
Cover Letter requirements are not specified.
Abstract
An abstract is required for Review articles. The abstract must be structured and presented as a single paragraph.
Manuscript
Review articles must not exceed 12,000 words. Review articles must be organized as Abstract, Introduction, subject-relevant subsections, and Discussion. The manuscript must acknowledge any use of generative AI content in the acknowledgements section, or in the methods section if applicable, including the tool name, version, model, and source.
References
References must follow the journal reference style, list the first six authors followed by et al. with initials for given names and DOI when available, and must not include unpublished material or personal communications.
Figures & Tables
Figures must be submitted individually with captions placed at the end of the manuscript, and tables must be inserted at the end of the manuscript in editable format. All figures or images must include alternative text.
Mini Review
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract must be structured and written as a single paragraph.
Manuscript
Manuscript must not exceed 3,000 words. Manuscript must be organized as Abstract, Introduction, subject-relevant subsections, and Discussion. The first page must state the manuscript word count and the number of figures and tables, and any use of generative AI for written or visual content must be acknowledged in the acknowledgements or methods section with the tool name, version, model, and source.
References
References must follow the journal's reference style, list the first six authors followed by et al. with initials for given names and DOI when available, and Mini Reviews must not cite unpublished material or personal communications.
Figures & Tables
Mini Review articles may include no more than 2 figures and/or tables in total. Figures must be submitted individually with captions placed at the end of the manuscript, and tables must be inserted at the end of the manuscript in editable format. All figures must include alternative text and be cited in numerical order, with multi-panel figures labeled as (A), (B), (C), and so on.
Policy And Practice Reviews
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract should be structured and presented as a single paragraph.
Manuscript
Manuscript must not exceed 12,000 words. Manuscript should be organized as Abstract, Introduction, sections on assessment of policy or guidelines options and implications, Actionable Recommendations, and Discussion. Manuscript must include 5 to 8 keywords and acknowledge any use of generative AI in the acknowledgements section and in the methods section if applicable, including the tool name, version, model, and source.
References
References must follow the journal's reference style, list the first six authors followed by et al. with authors' given names abbreviated to initials, and include the DOI when available.
Figures & Tables
Figures must be submitted individually with captions at the end of the manuscript, and tables must be inserted at the end of the manuscript in editable format. All figures or images must include alternative text.
Case Report
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract must be structured and presented as a single paragraph.
Manuscript
Manuscript must not exceed 3,000 words. Title must follow the format "Case Report: 'area of focus'" and the manuscript must be organized with headings and subheadings. Manuscript must include an acknowledgement or methods disclosure naming the generative AI tool, version, model, and source if written or visual content was produced by or edited using generative AI.
References
Citations and references must adhere to the journal's reference style. References must list the first six authors followed by et al., abbreviate given names to initials, and include the DOI when available.
Figures & Tables
Case Reports may include no more than 4 display items in total, including figures, tables, or videos. Figures must be submitted individually and figure captions and tables must be placed at the end of the manuscript. All figures or images must include alternative text.
Data Report
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract must be structured and presented as a single paragraph.
Manuscript
Manuscript must not exceed 3,000 words and may include no more than 2 figures and/or tables. Manuscript should be organized as Introduction; Methods used to collect the data, including the data collection period, filters applied, and guidance on interpretation and reuse; some analysis of the data; relevant subsections; and no Results or Discussion sections. Manuscript must include the dataset name, the database or repository where the dataset was submitted, the confidential peer-review link to the dataset to be replaced by the public link before publication, and an acknowledgement of any generative AI use in the acknowledgements or methods section with the tool name, version, model, and source.
References
References must follow the journal's reference style and list the first six authors followed by et al., abbreviate given names to initials, include DOIs when available, and include deposited datasets with version and unique identifier when available.
Figures & Tables
Data Report articles may include no more than 2 figures and/or tables. Figures must be submitted individually with captions at the end of the manuscript, and tables must be inserted at the end of the manuscript in editable format. All figures must include alternative text, be cited in numerical order, and use panel labels where applicable.
Brief Research Report
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract should be structured in a single paragraph.
Manuscript
Manuscript must not exceed 4,000 words. Manuscript should be organized as Abstract, Introduction, Method, Results, and Discussion. Manuscript must include an acknowledgement in the acknowledgements section, and in the methods section if applicable, disclosing any use of generative AI with the name, version, model, and source of the technology.
References
References should list the first six authors followed by et al. and include the DOI when available.
Figures & Tables
Manuscript may contain no more than 4 figures and tables in total. Figures must be submitted individually and figure captions placed at the end of the manuscript, while tables should be inserted at the end of the manuscript in editable format. All figures or images must include alternative text.
Technology And Code
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract must be structured and presented as a single paragraph.
Manuscript
Manuscript must not exceed 12,000 words. Manuscript should be organized as Abstract, Introduction, Method including any code description, Results including examples of use and limitations, and Discussion including scalability and limitations. Manuscript must include the project link, operating system, programming language, any restrictions for non-academic use, and an acknowledgement of any generative AI use with the name, version, model, and source of the tool in the acknowledgements or methods section as applicable.
References
References should list the first six authors followed by et al., abbreviate given names to initials, include the DOI when available, and ensure every cited item appears in the reference list and every reference list item is cited in the text, figures, or tables.
Figures & Tables
Figures must be submitted individually with captions placed at the end of the manuscript, while tables must be inserted at the end of the manuscript in editable format. All figures or images must include alternative text.
Fair² Data
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract must be structured and presented as a single paragraph.
Manuscript
Manuscript must not exceed 12,000 words. Manuscript must be organized using headings and subheadings. Manuscript must include an acknowledgement of any generative AI use in the acknowledgements section or methods section as applicable, including the tool name, version, model, and source.
References
References must follow the journal's reference style, list the first six authors followed by et al. when applicable, and include the DOI when available.
Figures & Tables
A maximum of 15 figures or tables may be included. Figures must be submitted individually and table files must be placed at the end of the manuscript. Figure captions must be placed at the end of the manuscript and table captions must appear immediately before each table.
Recent Publications
Finite element analysis of medial meniscus tears and related surgical techniques with biomechanical validation
Chengyue Yu, Kexin Liu, Jingyu Zhang, Wenjun Zhao, Xiaoyuan Duan, Bo Liu, Lupeng Wang, Zhao Liu, Yongxin Huo, Tao Zhang, Guosheng Xing, Weiguo Xu
10.3389/fbioe.2026.1916206
View Publication
A 3D engineered multiple myeloma niche for evaluating CAR T cell therapy
Lorea Jordana-Urriza, Manuele G. Muraro, Marc Du, Victoria Lambrecht, Juan Roberto Rodriguez-Madoz, Ivan Martin, Andrés García-García
10.3389/fbioe.2026.1860416
View Publication
Anticipation-angle interaction identifies 45° unanticipated change of direction as a high-demand movement with altered ACL injury-related biomechanical characteristics
Chuangui Mao, Shidong Xie, Ziwen Wang, Xin Yang, Zhiyu Guan, Yuangai Huang, Yongyue Huang, Weiguo Liu
10.3389/fbioe.2026.1895455
View Publication
Key biomechanical features of jump-landing under cognitive dual-task conditions: an XGBoost-SHAP-based explainable machine learning analysis
Yuhang Zhu, Yanlong Zhang, Qingqing Ma, Minting Fang, Ronghe Cui, Xiao Yu, Si Chen
10.3389/fbioe.2026.1930588
View Publication
Advances and prospects of 3D air-liquid interface cultured middle ear epithelial cells and inner ear organoids in otologic diseases
Le Gu, Mengxian Du, Kai Zhang, Yuancheng Wu, Tihua Zheng, Qingyin Zheng, Bo Li
10.3389/fbioe.2026.1881504
View Publication
Frequently asked questions
How long does it take to publish?
Average of 90 days from submission to acceptance and 12 days from acceptance until the final typeset document.
Reformat to Frontiers in Bioengineering and Biotechnology using Livewrite PremiumIs a cover letter required?
A traditional cover letter is not permitted. Authors must instead prepare a 200-word contribution-to-the-field statement.
Reformat to Frontiers in Bioengineering and Biotechnology using Livewrite PremiumWhat are the publication costs?
Article processing charges are CHF 3,150 for A-Type Articles and CHF 2,500 for B-Type Articles. APC support or discounts may be available through institutional partnerships or author support programs.
Reformat to Frontiers in Bioengineering and Biotechnology using Livewrite PremiumResearch Topics
Bone Tissue Engineering Materials
Electrospun Nanofibers in Biomedical Applications
3D Printing in Biomedical Research
Tissue Engineering and Regenerative Medicine
Microbial Metabolic Engineering and Bioproduction
Orthopaedic implants and arthroplasty
Nanoplatforms for cancer theranostics
Biofuel production and bioconversion
Periodontal Regeneration and Treatments
Osteoarthritis Treatment and Mechanisms
Mesenchymal stem cell research
Nanoparticle-Based Drug Delivery
CRISPR and Genetic Engineering
RNA Interference and Gene Delivery
Graphene and Nanomaterials Applications
Advanced biosensing and bioanalysis techniques
Dental Implant Techniques and Outcomes
biodegradable polymer synthesis and properties
Wound Healing and Treatments
Extracellular vesicles in disease
Enzyme Catalysis and Immobilization
Spine and Intervertebral Disc Pathology
Viral Infectious Diseases and Gene Expression in Insects
Muscle activation and electromyography studies
Total Knee Arthroplasty Outcomes
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