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Frontiers in Oncology

Frontiers in Oncology publishes global oncology research on carcinogenesis, tumor progression, cancer diagnosis, treatment, and management across diverse populations and healthcare systems. The journal highlights community-driven editorial oversight, journal metrics including a 3.3 Impact Factor and 6.9 CiteScore, and specialty sections spanning multiple oncology fields.

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Subject Oncology
Impact Factor 3.3
Quartile Q2
Open Access Type Open
ISSN 2234-943X
eISSN 2234-943X
Invitation Only No
Cost Range CHF 3,150 for A-Type Articles; CHF 2,500 for B-Type Articles.

Submission Instructions

Frontiers in Oncology accepts the following article types. Click on an article type to view submission instructions.

Original Research

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured in a single paragraph, for example following IMRAD.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should follow the format Abstract, Introduction, Materials and Methods, Results, and Discussion, or field-appropriate equivalent sections, with a succinct Introduction without subheadings. Use of written or visual content produced by or edited using generative AI must be acknowledged in the acknowledgements section with the name, version, model, and source of the technology.
References References must list the first six authors followed by et al., abbreviate given names to initials, and ensure every in-text, figure, or table citation appears in the reference list and vice versa.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, and tables must be inserted directly into the manuscript at the end in editable form. Multi-panel figures must use labels such as (A), (B), (C), and each figure and table must be mentioned in the text.
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Systematic Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured in a single paragraph.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should follow the format Abstract, Introduction, Methods, Results, and Discussion, with Methods covering study design, participants, interventions, comparators, protocol, search strategy, data sources, study selection and data extraction, and data analysis, Results covering study retrieval flow, study selection and characteristics, synthesized findings, and risk of bias assessment, and Discussion covering main findings, limitations, and conclusions. Manuscript must clearly define the research question in PICOS terms and include at least five keywords, funding information, and an acknowledgment of generative AI use in the acknowledgements section if such technology was used.
References References must list the first six authors followed by et al., abbreviate given names to initials, include only published or accepted works, and must not include unpublished material, submitted manuscripts, or personal communications.
Figures & Tables Figures must be submitted individually with captions at the end of the manuscript, while tables must be directly inserted at the end of the manuscript in editable form. Figure panels must be labeled (A), (B), (C), etc., each figure and table must be cited in the text, graphs must include self-explanatory axis labels with units, and figure captions must be preceded by the appropriate figure label while table captions must appear immediately before the table with the appropriate table label.
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Review

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must be structured in a single paragraph.
Manuscript Manuscript must not exceed 12,000 words. Manuscript must be organized as Abstract, Introduction, subject-relevant subsections, and Discussion. At least five keywords are required, and any use of generative AI for written or visual content must be acknowledged in the acknowledgements section with the name, version, model, and source of the technology.
References References must include the first six authors followed by et al., use abbreviated given names as initials, and exclude unpublished material such as personal communications or submitted manuscripts.
Figures & Tables Figures must be submitted individually with captions at the end of the manuscript, while tables must be inserted directly into the manuscript at the end in editable form. Each figure and table must be cited in the text, and multi-panel figures must use clearly indicated labels such as (A), (B), (C), and (D).
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Mini Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be a single paragraph and the manuscript format requires an Abstract section.
Manuscript Mini Review articles must not exceed 3,000 words. Mini Review articles must be organized as Abstract, Introduction, subject-relevant subsections, and Discussion. Mini Review articles should discuss different schools of thought or controversies, current research gaps, potential future developments, and acknowledge any generative AI use in the acknowledgements section with the name, version, model, and source.
References References must list the first six authors followed by et al., use initials for given names, include only published or accepted works, and Mini Review articles must not cite unpublished material or personal communications.
Figures & Tables Mini Review articles may include no more than 2 figures and/or tables. Figures must be submitted individually with captions at the end of the manuscript, while tables must be inserted directly into the manuscript at the end in editable form. Each figure and table must be mentioned in the text, and multi-panel figures must use clearly labeled panels such as (A), (B), and (C).
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Clinical Trial

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required and must include the clinical trial registration information, including the Clinical Trials Unique Identifier, Registry Name, and URL. Abstract must be a single structured paragraph. Abstract must include the unique identifier of the trial and the URL of the publicly accessible trial registry website.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should be organized as Abstract including the clinical trial registry number, Introduction, Materials and Methods, Results, and Discussion. The first page must state the word count and the number of figures and tables, the manuscript must include at least five keywords, and any use of generative AI content must be acknowledged in the acknowledgements with the tool name, version, model, and source.
References References must be cited consistently between text and reference list, list the first six authors followed by et al. with given names abbreviated to initials, and include only published or accepted works.
Figures & Tables Figures must be submitted individually with captions at the end of the manuscript, while tables must be inserted directly into the manuscript at the end in editable form. Each figure and table must be cited in the text, multi-panel figures must use labels such as (A), (B), and randomized clinical trials must include a CONSORT flow diagram in the figures or supplementary material.
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Case Report

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured in a single paragraph. Abstract is a required manuscript section in the format sequence Abstract; Introduction; Case description; Diagnostic assessment, details on the therapeutic intervention, follow-up and outcomes; Discussion; and Patient perspective.
Manuscript Manuscript must not exceed 3,000 words. Manuscript must follow the format Abstract; Introduction; Case description; a figure or table timeline; Diagnostic assessment, therapeutic intervention, follow-up and outcomes; Discussion; and Patient perspective. Manuscript must include at least five keywords, a title in the form "Case Report: 'area of focus'," and any generative AI use acknowledged in the acknowledgements with the tool name, version, model, and source.
References References must list the first six authors followed by et al., with given names abbreviated to initials, and every cited item must appear in the reference list and vice versa.
Figures & Tables Case Reports may include no more than 4 display items in total, including figures, tables, or videos. Figures must be submitted individually with captions at the end of the manuscript, while tables must be inserted directly into the manuscript at the end. The manuscript must include a figure or table presenting a timeline with relevant data from the episode of care.
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Community Case Study

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured in a single paragraph. Abstract should be followed by Introduction, Context setting and population, Detail to understand key programmatic elements, Discussion, and Acknowledgment of conceptual or methodological constraints in the manuscript.
Manuscript Manuscript must not exceed 5,000 words. Manuscript should be organized as Abstract; Introduction describing the problem and rationale for the innovation; Context setting and population; Detail to understand key programmatic elements; Discussion with practical implications and lessons learned; and Acknowledgment of conceptual or methodological constraints. At least five keywords are required, and any generative AI use must be acknowledged in the acknowledgements section with the name, version, model, and source of the tool.
References References must include the first six authors followed by et al., with given names abbreviated to initials, and every in-text citation must appear in the reference list and vice versa.
Figures & Tables No more than 5 figures and/or tables are allowed. Figures must be submitted individually with captions at the end of the manuscript, while tables must be inserted directly into the manuscript at the end. Each figure and table must be mentioned in the text, and multipanel figures must use labels such as (A), (B), and (C).
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Data Report

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured in a single paragraph, for example following IMRAD format.
Manuscript Manuscript must not exceed 3,000 words. Manuscript should be organized as Introduction; Methods used to collect the data including the data collection period, filters applied, and information on dataset interpretation and reuse; some analysis of the data; and relevant subsections, with no Results or Discussion sections. Manuscript must include the dataset name, the database or repository where the dataset was submitted, the confidential peer review link to be updated to a public link before publication, at least five keywords, and an acknowledgement section disclosing any generative AI use with the tool name, version, model, and source.
References References must list the first six authors followed by et al., abbreviate given names to initials, include only published or accepted works, and ensure every in-text, figure, or table citation appears in the reference list and vice versa.
Figures & Tables Data Report articles may contain no more than 2 figures and tables in total. Figures must be submitted individually with captions at the end of the manuscript, while tables must be directly inserted into the manuscript at the end in editable form. Each figure and table must be mentioned in the text, and multi-panel figures must use clearly indicated panel labels such as (A), (B), and so on.
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Brief Research Report

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured as part of the format Abstract; Introduction; Method; Results; Discussion and must be no longer than a single paragraph.
Manuscript Manuscript must not exceed 4,000 words. Manuscript should follow the format Abstract; Introduction; Method; Results; Discussion. Manuscript must include at least five keywords, and any use of generative AI for written or visual content must be acknowledged in the acknowledgements section with the name, version, model, and source of the technology.
References References must include the first six authors followed by et al., with given names abbreviated to initials, and every in-text, figure, or table citation must appear in the reference list and vice versa.
Figures & Tables Brief Research Report articles may contain no more than 4 figures and tables in total. Figures must be submitted individually with captions at the end of the manuscript, while tables must be directly inserted at the end of the manuscript in editable form. Each figure and table must be mentioned in the text, multi-panel figures must use labels such as (A), (B), (C), and graphs must include self-explanatory axis labels with units where applicable.
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Technology And Code

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be included and the article should follow the format Abstract, Introduction, Method including any code description, Results including examples of use and limitations, and Discussion including scalability and limitations.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should be organized as Abstract, Introduction, Method including any code description, Results including examples of use and limitations, and Discussion including scalability and limitations. Manuscript must include the project link, operating system, programming language, any restrictions for non-academic use, and an acknowledgement section disclosure naming the generative AI technology used with its version, model, and source if applicable.
References References must list the first six authors followed by et al., abbreviate given names to initials, and include only works that are published or accepted.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, while tables must be directly inserted into the manuscript. Figure panels must be labeled sequentially, each figure and table must be cited in the text, and tables must be provided in editable source form rather than as figures.
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Fair² Data

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured in a single paragraph, for example according to the IMRAD format.
Manuscript Manuscript must not exceed 12,000 words. Manuscript must be organized by headings and subheadings. Any written or visual content produced by or edited using generative AI must be acknowledged in the acknowledgements section with the name, version, model, and source of the technology.
References References must list the first six authors followed by et al., with given names abbreviated to initials.
Figures & Tables FAIR² Data articles may include up to 15 figures or tables. Figures must be submitted individually, while tables must be inserted directly into the manuscript. Figure captions must be placed at the end of the manuscript, and tables must be provided in editable source form rather than as figures.
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Recent Publications

Preliminary evaluation of ProSpare®, a rectal obturator for prostate bed radiotherapy within the randomised multicentre POPS trial (NCT02978014)

Sarah Stewart, Karen Thomas, Jenni Parmar, Alison Claire Tree, Chris Parker, Helen McNair, Sophie Alexander, Julia Henderson, James Talbot, Christopher Scrase, Chee Goh, Reena Davda, Emma Gray, Peter Hoskin, Sarah Needleman, Jenny Nobes, Kamalram Thippu Jayaprakash, Yvonne Rimmer, Ranachandran Venkitaraman, Anna Wilkins, Vincent Khoo, Julia Murray, David Paul Dearnaley

10.3389/fonc.2026.1758462
View Publication

Clinical outcomes and prognostic factors in pediatric acute myeloid leukemia with monocytic differentiation: a single-center cohort study from Egypt

Tarek Ahmed Abdelrehim Ahmed, Mahmoud Hammad, Sonya Soliman, Nahla Elsharkawy, Sherine Ibrahim Salem, Sonia Ahmed, Alaa Elhaddad

10.3389/fonc.2026.1969723
View Publication

Treating a systemic disease as a local one: failure points of current pancreatic cancer management and a multimodal, biology-guided framework for redesign

Patrick E. Sewell

10.3389/fonc.2026.1941793
View Publication

Case Report: From unresectable to resectable: successful conversion therapy with TACE, HAIC, envafolimab, and olaparib in advanced intrahepatic cholangiocarcinoma

Chi Ma, Kun Feng, Jun Zhou

10.3389/fonc.2026.1935499
View Publication

Risk factors associated with colorectal adenomas and the formulation of prediction models

Haoming Yu, Zongyu Qiu, Wenyao Sui, Shengyu Han, Jihong Li, Wenhua Lan, Xuan Sun, Yuhua Chi

10.3389/fonc.2026.1894239
View Publication

Frequently asked questions

How long does it take to publish?

Is a cover letter required?

A traditional cover letter is not allowed. Authors must prepare a 200-word contribution-to-the-field statement during submission.

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What are the publication costs?

Article processing charges are CHF 3,150 for A-Type Articles and CHF 2,500 for B-Type Articles. APC support or discounts may be available through institutional partnerships and eligibility programs.

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Research Topics

Cancer Immunotherapy and Biomarkers Ferroptosis and cancer prognosis Radiomics and Machine Learning in Medical Imaging Cancer-related molecular mechanisms research Glioma Diagnosis and Treatment Lung Cancer Treatments and Mutations Lung Cancer Diagnosis and Treatment RNA modifications and cancer Hepatocellular Carcinoma Treatment and Prognosis Lung Cancer Research Studies Cancer, Hypoxia, and Metabolism Cancer Genomics and Diagnostics Head and Neck Cancer Studies Breast Cancer Treatment Studies Advanced Radiotherapy Techniques MicroRNA in disease regulation Pancreatic and Hepatic Oncology Research Gastric Cancer Management and Outcomes Inflammatory Biomarkers in Disease Prognosis Cancer Cells and Metastasis Epigenetics and DNA Methylation Cholangiocarcinoma and Gallbladder Cancer Studies Endometrial and Cervical Cancer Treatments Esophageal Cancer Research and Treatment Immune cells in cancer

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