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Journal Of Clinical Oncology

Journal of Clinical Oncology is an ASCO journal covering clinical oncology research and publishing article types including original reports, clinical trial updates, special articles, correspondence, rapid communications, and ASCO special articles.

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Subject Oncology
Impact Factor 41.9
Quartile Q1
Open Access Type Hybrid
ISSN 0732-183X
eISSN 1527-7755
Invitation Only No
Cost Range A submission fee is mentioned for Case Reports submitted to Journal of Clinical Oncology and not refunded if withdrawn.

Submission Instructions

Journal Of Clinical Oncology accepts the following article types. Click on an article type to view submission instructions.

Biology Of Neoplasia

Cover Letter A cover letter is required. Cover letter must describe the significance and uniqueness of the work and note any prior correspondence with the journal and any prior conference presentation, if applicable.
Abstract An abstract is required. Abstract must not exceed 275 words. Abstract must be structured. Abstract must use the headings PURPOSE, PATIENTS AND METHODS (or MATERIALS AND METHODS, METHODS, or a similar heading), RESULTS, and CONCLUSION.
Manuscript Manuscript must not exceed 4000 words, although initial submission may exceed this limit by up to 1000 words.
References References are limited to 150. References must be numbered in the order in which they are cited in the text.
Figures & Tables Figures and tables are limited to 6 combined. Tables must be placed at the end of the manuscript, and figures may be embedded in the manuscript instead of uploaded separately. Figure legends must be included in the manuscript file, and tables must be cited in numerical order using Arabic numerals.
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Original Reports

Cover Letter A cover letter is required. Cover letter must describe the significance and uniqueness of the work, note any similar work previously reported by the authors, disclose any prior correspondence with the journal, and be addressed to the Editor-in-Chief.
Abstract A structured abstract is required. Abstract must be 275 words. Abstract must be structured. Abstract must use the headings PURPOSE, PATIENTS AND METHODS or a similar methods heading, RESULTS, and CONCLUSION.
Manuscript Manuscript must not exceed 3000 words, although initial submission may exceed this limit by up to 1000 words. Manuscript must include a Context Summary following the title page at revision with Key objective, Knowledge generated, and Relevance sections. At revision, the manuscript must include a Context Summary of fewer than 100 words in which Key objective is a single question defining the content and novelty, Knowledge generated consists of two short result sentences without conclusions or interpretation, and Relevance explains clinical application.
References References must be numbered in the order in which they are cited in the text.
Figures & Tables Original Reports are limited to 6 figures and tables combined. Tables must be placed at the end of the manuscript, and figures may be embedded in the manuscript instead of uploaded separately. Figure legends must be included in the manuscript file, and extended patient demographic data should be presented in a table rather than in the text.
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Review Articles

Cover Letter A cover letter is required. Cover letter must describe the significance and uniqueness of the work, include any similar work previously reported by the authors, and note any prior correspondence with the journal about the manuscript.
Abstract An abstract is required. Abstract must be 275 words. Systematic reviews, consensus guidelines, and meta-analyses must use a structured abstract, while other Review Articles must use an unstructured abstract. Structured abstracts must use the headings PURPOSE, PATIENTS AND METHODS, RESULTS, and CONCLUSION, with DESIGN permitted instead of PATIENTS AND METHODS for Review Articles.
Manuscript Manuscript must not exceed 4000 words, although initial submission may exceed this limit by no more than 1,000 words. Review Articles should be disease-focused, examine new data in the field, and describe applications to practice. Review Articles may include one optional graphical abstract at revision, submitted separately, with text under 100 words and 1 to 3 figures.
References References are limited to 150. References must be numbered in the order in which they are cited in the text.
Figures & Tables Review Articles are limited to 6 figures and tables combined. Tables must be placed at the end of the manuscript, and figures may be embedded in the manuscript rather than uploaded separately if included there. Figure legends must be included in the manuscript file, and table pieces such as Table 1a and 1b are not allowed.
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Brief Reports

Cover Letter A cover letter is required. Cover letter must describe the significance and uniqueness of the work and note any prior correspondence with the journal and any prior conference presentation, if applicable.
Abstract A structured abstract is required. Abstract must be 275 words. Abstract must be structured. Abstract must use the headings PURPOSE, PATIENTS AND METHODS (or MATERIALS AND METHODS, METHODS, or a similar heading), RESULTS, and CONCLUSION.
Manuscript Manuscript must not exceed 1500 words, although initial submission may exceed this limit by no more than 1,000 words.
References References must be numbered in the order in which they are cited in the text.
Figures & Tables Brief Reports are limited to 3 figures and tables combined. Tables must be placed at the end of the manuscript, and figures may be embedded in the manuscript file rather than uploaded separately. Figure legends must be included in the manuscript file, and tables must be cited in the order in which they appear in the text using Arabic numerals.
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Case Reports

Cover Letter A cover letter is required. Cover letter must describe the significance and uniqueness of the work and note any prior correspondence with the journal.
Abstract Abstract is not required for Case Reports.
Manuscript Case Reports must not exceed 1500 words, although initial submission may exceed this limit by no more than 1000 words. Case Reports should provide a brief overview of the case and a concise literature review. Case Reports must be supported by data, should provide access to primary data, and should include clear evidence of exceptional response or resistance, a proposed mechanism linking genomic features to response or resistance to targeted therapy, and the variant, platform, and targeted therapy used.
References Case Reports are limited to 20 references. References must be numbered in the order in which they are cited in the text.
Figures & Tables Case Reports are limited to 3 figures and tables combined. If figures are included within the manuscript, they do not need to be uploaded separately, and tables must be placed at the end of the manuscript. Figure legends must be included in the manuscript file, and tables must be cited in the order in which they appear in the text using Arabic numerals.
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Clinical Trial Updates

Cover Letter A cover letter is required. Cover letter must describe the significance and uniqueness of the work, note any similar previously reported work and any prior correspondence with the journal, and be addressed to the Editor-in-Chief.
Abstract An abstract is required. Abstract must be 200 words. Abstract must be unstructured.
Manuscript Manuscript must not exceed 1200 words, although initial submission may exceed this limit by no more than 1,000 words. Clinical Trial Updates should include a brief description of the trial and a short summary of previous findings to provide context. Updates to randomized phase II and all phase III trials must include a redacted study protocol.
References References must be numbered in the order in which they are cited in the text.
Figures & Tables Clinical Trial Updates are limited to 3 figures and tables combined. Tables must be placed at the end of the manuscript, and figures may be embedded in the manuscript rather than uploaded separately. Table 1 must include information regarding the patient population, even if repeated from the original publication.
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Correspondence

Cover Letter A cover letter is required. Cover letter must describe the significance and uniqueness of the work, include any similar work previously reported by the authors, and note any prior correspondence with the journal about the manuscript.
Abstract Abstract requirements are not specified.
Manuscript Correspondence must not exceed 750 words. Correspondence responding to a JCO article must include the reference to that article and use an original title that differs from the article. Authors should not use artificial intelligence or large language models to generate Correspondence.
References Correspondence is limited to 10 references. References must be numbered in the order in which they are cited in the text.
Figures & Tables Tables must be placed at the end of the manuscript, and figures may be embedded in the manuscript file rather than uploaded separately. Figure legends must be included in the manuscript file.
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Special Articles

Cover Letter A cover letter is required. Cover letter must describe the significance and uniqueness of the work, include any similar work previously reported by the authors, note any prior correspondence with the journal, and disclose prior conference presentations if applicable.
Abstract An abstract is required. Abstract must not exceed 275 words. Abstract must be structured. Abstract must use the headings PURPOSE, PATIENTS AND METHODS (or MATERIALS AND METHODS, METHODS, or a similar heading), RESULTS, and CONCLUSION.
Manuscript Manuscript must not exceed 4000 words, although initial submission may exceed this limit by no more than 1,000 words. Special Articles should explicitly state the methods used to select committee membership, clearly describe deliberation processes, and explicitly state funding sources.
References References must be numbered in the order in which they are cited in the text.
Figures & Tables Special Articles are limited to 6 figures and tables combined. Tables must be placed at the end of the manuscript, and figures may be embedded in the manuscript file rather than uploaded separately if included there. Figure legends must be included in the manuscript file, and tables must be cited in the order in which they appear in the text using Arabic numerals.
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Recent Publications

Addition of Metastasis-Directed Therapy to Standard of Care for Oligometastatic Solid Tumors: Primary Analysis of All Tumor-Histology Baskets of the Phase II Randomized EXTEND Trial

Alexander D. Sherry, Cara Haymaker, Shuqi Wang, Suyu Liu, Tharakeswara K. Bathala, Marina N. Medina-Rosales, Aaron Seo, Kieko Hara, Jay Reddy, Stephen G. Chun, Lauren L. Mayo, Gary Walker, Shubham Pant, Dan Zhao, Craig A. Kovitz, David Ramirez, Chul S. Ha, Benjamin D. Smith, Daniel Gomez, Lorenzo Cohen, Albert C. Koong, Alexandre Reuben, Nizar Tannir, Paul G. Corn, Phuoc T. Tran, Bilal A. Siddiqui, Sumit K. Subudhi, Pavlos Msaouel, Ethan B. Ludmir, Chad Tang

10.1200/jco-25-02856
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Overall Survival Among Patients With Hepatocellular Carcinoma Treated With External Beam Radiation Therapy: Individual Patient Data Outcomes From a Multinational Cohort

Andrew M. Moon, Ted K. Yanagihara, Laura A. Dawson, Jeong Il Yu, Theodore S. Lawrence, Tae Hyun Kim, Michael Yan, Hiromitsu Iwata, Nima Nabavizadeh, Smith Apisarnthanarax, Emma M. Dunne, Michael I. Lock, Michael D. Chuong, Chi Leung Chiang, Marta Scorsetti, Norio Katoh, Shirin Sioshansi, Kazushi Numata, Howard Yu-hao Liu, Hideki Iwamoto, Masaru Wakatsuki, Yixing Chen, Erqi L. Pollom, Eleni Gkika, Salma K. Jabbour, Pablo Munoz-Schuffenegger, Debnarayan Dutta, Carla Hajj, Masayuki Ueno, Christopher L. Hallemeier, Aharon M. Feldman, Alejandra Méndèz Romero, Xianming Tan, Meritxell Molla, Joel E. Tepper, Ferran Torres, Maria Reig, Alanah M. Bergman, Christopher Crane, Kyle C. Cuneo, Natalie Grindrod, Anca-Ligia Grosu, Rodrigo El Far, Ciro Franzese, Akihiro Funaoka, Marissa Gilbert, Satoshi Itasaka, Sung Uk Lee, Yoo Young Dominique Lee, Joel Mases, Hiroyuki Ogino, Vera Qu, Hee Chul Park, Ramtin Rahmani, Lee Ann Shing, Tomotake Shirono, Teodor Stanescu, Kanokphorn Thonglert, Wilhelm den Toom, Yusuke Uchinami, Zhaochong Zeng

10.1200/jco-25-02399
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Bridging the Gap: Integrating External Beam Radiation Therapy Into the Management of Hepatocellular Carcinoma

Sunil W. Dutta, Naba Ali, Pretesh R. Patel, Shannon Offerman

10.1200/jco-26-00521
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Multicenter Cohort Study of Original or Substitute Systemic Therapy With or Without Brain Radiotherapy for Extensive-Stage Small Cell Lung Cancer With Brain-Only Progression After First-Line Treatment

Shuangqing Lu, Jingyi Jia, Kai Ren, Wenxiao Jia, Zhuoran Sun, Ke Zhao, Xuwei Cai, Lujun Zhao, Hui Zhu

10.1200/jco-25-02536
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Efficacy and Safety of Camrelizumab Plus Apatinib in Patients With Refractory Chordoma: A Phase II Clinical Trial

Cheng Yang, Qi Jia, Chenglong Zhao, Xinghai Yang, Haifeng Wei, Tielong Liu, Jian Jiao, Zhipeng Wu, Jian Zhao, Wei Xu, Zhenhua Zhou, Wei Wan, Weiwei Zou, Zhi Zhu, Xiaomei Ma, Qi Chen, Wei Guo, Dongqing Zhu, Tao Tan, Yan Lou, Juelan Ye, Jingyu Xing, Hao Zhang, Zijie Yuan, Jianru Xiao

10.1200/jco-25-02719
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Frequently asked questions

How long does it take to publish?

Published three times per month — a total of 36 issues per year.

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Is a cover letter required?

A cover letter is required as part of the required information for submission under the format-free EZSubmit policy.

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What are the publication costs?

Journal of Clinical Oncology charges an $80 USD submission fee for Original Reports.

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Research Topics

Lung Cancer Treatments and Mutations Cancer Treatment and Pharmacology Colorectal Cancer Treatments and Studies Cancer Genomics and Diagnostics Cancer Immunotherapy and Biomarkers Gastric Cancer Management and Outcomes Prostate Cancer Treatment and Research Lung Cancer Research Studies Breast Cancer Treatment Studies Economic and Financial Impacts of Cancer Lymphoma Diagnosis and Treatment Cancer Diagnosis and Treatment Pancreatic and Hepatic Oncology Research HER2/EGFR in Cancer Research Radiomics and Machine Learning in Medical Imaging Multiple and Secondary Primary Cancers Renal cell carcinoma treatment Advanced Breast Cancer Therapies Bladder and Urothelial Cancer Treatments Chronic Lymphocytic Leukemia Research Hepatocellular Carcinoma Treatment and Prognosis Lung Cancer Diagnosis and Treatment Radiopharmaceutical Chemistry and Applications Cholangiocarcinoma and Gallbladder Cancer Studies Sarcoma Diagnosis and Treatment

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