SV

Signa Vitae

Signa Vitae (SV) is a peer-reviewed, open-access journal focused on recognition, monitoring, intervention, nursing, and improvement of vital signs, emphasizing acute conditions requiring immediate intervention, life-threatening critical states, anesthetic techniques and perioperative management, and pain assessment and management in acute, critical care, perioperative, and severe chronic pain settings. The journal encourages submissions on risk factors, etiology, pathophysiological mechanisms, prognostic assessment, outcome improvement strategies, and disease management related to these conditions.

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Subject Emergency Medicine
Impact Factor 0.6
Quartile Q4
Open Access Type Open
ISSN 1334-5605
eISSN 1845-206X
Invitation Only No
Cost Range Article Processing Charges are required only after a manuscript is accepted for publication.

Submission Instructions

Signa Vitae accepts the following article types. Click on an article type to view submission instructions.

Original Research

Cover Letter A cover letter is required summarizing the important points of the work, confirming originality and that it is not under consideration elsewhere, stating all authors’ approval, ethics approval and informed consent where applicable, and disclosing any conflicts of interest or competing interests.
Abstract A structured abstract (max 300 words) is required with the headings Background, Methods, Results, Conclusions, and Clinical Trial Registration if applicable.
Manuscript Original Research manuscripts should follow an IMRaD structure with separate Introduction, Materials and Methods, Results, Discussion, and Conclusions sections, plus standard front matter (title, authors, abstract, keywords) and back matter (e.g., Acknowledgments, Author Contributions, Ethics, Funding, Conflicts of Interest, Supplementary Materials, References, Figure Legends, Data Availability); no overall word limit is specified.
References References are numbered in order of appearance using a Vancouver-style numeric system, cited in the text with bracketed numbers at sentence ends, listed with full author names up to six then ‘et al.’ thereafter, full journal titles, non-abbreviated page ranges, and indication of non-English journal language; no maximum reference count is indicated.
Figures & Tables Figures must be submitted as high-resolution JPG or TIF files in RGB (900–1200 dpi line art, 500–900 dpi combination, 300 dpi halftones), labeled sequentially (Fig. 1, Fig. 2, etc.) with separate detailed legends, and are strongly encouraged to have no more than six panels per figure, while tables must be editable (not images), numbered sequentially with short titles and footnotes; no explicit maximum number of figures or tables is specified.
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Systematic Review

Cover Letter A cover letter is required summarizing the key points of the work, confirming originality and that it is not under consideration elsewhere, stating author approval and relevant ethics approvals/consents, and disclosing any conflicts of interest or competing interests.
Abstract A structured abstract (max 300 words) is required with the headings Background, Methods, Results, Conclusions, and Clinical Trial Registration (if applicable).
Manuscript No overall manuscript word limit is specified for systematic reviews.
References No maximum reference count is indicated.
Figures & Tables A graphical abstract is optional and, if provided, must be submitted as a separate file at ≥300 dpi in .tif, .jpg, or .png format.
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Review Article

Cover Letter A cover letter is required summarizing the key points of the work, confirming originality and exclusive submission, author approval, relevant ethics approval and informed consent, and disclosing any conflicts of interest or competing interests.
Abstract An unstructured abstract is required as a single paragraph not exceeding 300 words.
Manuscript Review Articles normally include abstract, keywords, introduction, relevant thematic sections, discussion, conclusions, and future directions, with standard front matter (title, author information, abstract, keywords) and back matter (Acknowledgments, Author Contributions, Ethics, Funding, Conflicts of Interest, Supplementary Materials, References, Figure Legends, Data Availability Statement when applicable); no overall word limit is specified.
References References are numbered in order of citation using a Vancouver-style numerical system with full author lists for up to six authors and ‘et al.’ thereafter, full journal titles, unabbreviated page ranges, bracketed citation numbers at sentence ends, and language of non-English journals indicated in parentheses; no maximum reference count is indicated.
Figures & Tables Figures must be submitted separately as JPG or TIF in RGB (no alpha channel), labeled and cited in ascending numerical order with legends in a separate section, conforming to width/height guidelines and high-resolution requirements (900–1200 dpi line art, 500–900 dpi combination, 300 dpi halftones), with up to six panels per figure strongly encouraged and optional graphical abstracts at ≥300 dpi in .tif, .jpg, or .png; no maximum number of figures is specified.
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Case Report

Cover Letter A cover letter is required and must summarize the key points of the work, affirm originality and exclusive submission, confirm author approval and ethics approval/consent when applicable, and disclose any conflicts of interest or competing interests.
Abstract A structured abstract (max 300 words) is required with the headings Background, Case(s), and Conclusion.
Manuscript No specific overall word limit is specified for case reports, but manuscripts must use clearly numbered sections and subsections (e.g., 1., 1.1, 1.1.1) with appropriate front matter (title, author information, abstract, keywords) and back matter (Acknowledgments, Author Contributions, Ethics, Funding, Conflicts of Interest, Supplementary Materials, References, Figure Legends, Data Availability Statement when applicable).
References References are numbered in order of citation in the text using bracketed numbers, listed in numerical order with full author lists up to six authors then 'et al.' thereafter, full journal titles, and non-abbreviated page numbers; no maximum reference count is indicated.
Figures & Tables Figures must be submitted as high-resolution JPG or TIF files in RGB (900–1200 dpi for line art, 500–900 dpi for combination images, 300 dpi for halftones), labeled sequentially as Fig. 1, Fig. 2, etc., with legends provided in a separate section, and the number of panels per figure is strongly encouraged to be limited to six.
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Editorial

Cover Letter A cover letter is required summarizing the important points of the work, confirming originality and that it is not under consideration elsewhere, that all authors approve the submission, that ethics approval and informed consent were obtained when applicable, and disclosing any conflicts of interest.
Abstract Abstracts are not required for Editorials; abstract word limits and structure are therefore not specified.
Manuscript No specific overall word limit or standard section structure is specified for Editorials, but manuscripts must use clearly defined and numbered sections and subsections (e.g., 1., 1.1, 1.1.1) and be prepared in Times New Roman 12-point font with single line spacing and justified alignment.
References Number references in order of citation using bracketed numbers in the text; list essential references only, with full author lists up to six authors then ‘et al.’ after six, full journal titles, un-abbreviated page ranges, and indicate non-English journal language in parentheses (e.g., ‘(In Turkish)’); no maximum reference count is indicated.
Figures & Tables Figures must be cited in ascending numeric order in the text (e.g., ‘Fig. 1A’, ‘Fig. 1B’, ‘Fig. 2’), with legends provided in a separate section, while appendix or supplementary figures are cited as ‘Appendix Fig. 1’ or ‘Supplementary Fig. 1’ continuing the main numbering sequence; authors are encouraged to submit a separate Graphical Abstract file at ≥300 dpi in .tif, .jpg, or .png format, and no maximum figure or table counts are specified.
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Letter to the Editor

Cover Letter A cover letter is required summarizing the important points of the work, affirming originality and lack of prior or concurrent submission, confirming author approval and ethics/consent where applicable, and disclosing any conflicts of interest or competing interests.
Abstract Abstracts are not required for Letters to the Editor; keywords (3–10) must still be provided immediately after where an abstract would normally appear.
Manuscript Letters to the Editor must be concise, with a maximum of 500 words, and prepared in Times New Roman 12-point font, single-spaced, with justified alignment and clearly defined and numbered sections and subsections (e.g., 1., 1.1, 1.1.1).
References References are numbered in order of citation using bracketed numbers in the text, with full author lists for up to six authors then 'et al.' after six, full journal titles, unabbreviated page numbers, and indication of non-English journal language in parentheses; reference count is limited to essential citations with no explicit maximum number stated.
Figures & Tables Figures (including optional graphical abstracts) must be submitted as separate files in .tif, .jpg, or .png format at a minimum resolution of 300 dpi, cited in ascending numeric order in the text (e.g., Fig. 1A, Fig. 1B, Fig. 2), with all figure legends grouped in a separate section; no specific maximum number of figures or tables is indicated.
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Recent Publications

Early non-invasive ventilation for the management of patients with acute respiratory failure: a systematic review and meta-analysis

Rosario Losiggio, Paolo Pallavicini, Filippo Consolo, Tommaso Scquizzato, Filippo D’Amico, Federico Mattia Oliva, Luca Cabrini, Giacomo Monti, Alberto Zangrillo, Katia Donadello, Giovanni Landoni, NIV Study Group Collaborators, NIV Study Group Collaborators

10.22514/sv.2026.025
View Publication

Blind caudal epidural injection for sciatica in resource-limited practice: a narrative review

Vinko Sušac, Bojan Bender

10.22514/sv.2026.024
View Publication

Impact of tranexamic acid on intraoperative fluid intake in patients undergoing posterior spine fixation: a retrospective cohort study

Gisoon Park, Bosung Kim, Sang A Song, Seung Woo Song

10.22514/sv.2026.021
View Publication

Shortening the path to perfusion: why every link in the chain of survival shapes ECPR outcomes

Fabio Sangalli, Antonio Rubino

10.22514/sv.2026.022
View Publication

Epidemiological and clinical characteristics of acute ischemic stroke patients in a war zone

Hüseyin Gürbüz, Ali Muhsin Güvelioğlu, Yavuz Yücel, Süleyman Güler, Özgür Karcıoğlu

10.22514/sv.2026.020
View Publication

Frequently asked questions

How long does it take to publish?

Preliminary review is typically completed within 1–7 days with a median of 4 days, and the peer review process typically takes 4–14 weeks with a median of 8 weeks, though some articles may require longer than 14 weeks depending on manuscript complexity and reviewer availability.

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Is a cover letter required?

A cover letter is expected and should briefly summarize the key points of the work, confirm that the study is original and not under consideration elsewhere, state that all authors have approved the submission, indicate that ethics approval and informed consent have been obtained where applicable, and disclose any conflicts of interest.

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What are the publication costs?

Editorial board members are entitled to one free publication per year, and additional articles can receive a 30% discount on the publishing fee.

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Research Topics

Cardiac Arrest and Resuscitation Cardiac, Anesthesia and Surgical Outcomes Airway Management and Intubation Techniques Respiratory Support and Mechanisms Anesthesia and Pain Management

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