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Acta Biomaterialia

Acta Biomaterialia is an international journal that publishes peer-reviewed original research reports, review papers and communications in the broadly defined field of biomaterials science. The emphasis of the journal is on the relationship between biomaterial structure and function at all length scales.

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Impact Factor 9.6
Quartile Q1
Open Access Type Hybrid
ISSN 1742-7061
eISSN 1878-7568
Invitation Only No
Cost Range Open Access Article Publishing Charge (APC): USD 3,810 (excluding taxes); subscription publication: no publication fee charged to authors.

Submission Instructions

Acta Biomaterialia accepts the following article types. Click on an article type to view submission instructions.

Original Research Reports

Cover Letter Submission implies that publication is approved by all authors and by the responsible authorities where the work was carried out.
Abstract An abstract is required for Original Research Reports. Abstract must not exceed 250 words.
Manuscript Manuscript must be divided into clearly defined and numbered sections including separate Introduction, Materials and methods, Results, and Discussion sections. The manuscript must include a graphical abstract submitted separately, four to five keywords after the abstract, a Statement of Significance limited to 120 words, a Disclosures section before the references, and an AI declaration section before the references when AI was used in writing.
References References must use a numbered citation style with square-bracketed citations in the text. The reference list must be numbered in the order of first appearance in the text and include all author names and article titles for cited articles.
Figures & Tables Initial submission may include figures, tables, and captions inserted in the text, but each illustration must also be submitted as a separate file and captions provided separately. Figures and tables must be numbered consecutively in the order cited in the text, tables must be editable text rather than images, and all experimental and calculated data points must include error bars.
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Review Papers

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required for review papers. Abstract must not exceed 250 words.
Manuscript Articles must be divided into clearly defined and numbered sections. The manuscript must include a graphical abstract, four to five keywords immediately after the abstract, a Statement of Significance limited to 120 words, a Disclosures section before the references for conflicts of interest, and an AI declaration section before the references when AI-assisted writing was used.
References References must use a numbered citation style with square-bracketed citations in the text. The reference list must be numbered in order of first appearance and include all author names and the titles of all cited articles.
Figures & Tables Initial submission may be provided as a single file with figures, tables, and captions inserted in the text in the appropriate places. Tables must be submitted as editable text rather than images.
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Communications

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required for Communications. Abstract must not exceed 250 words.
Manuscript Manuscript must be divided into clearly defined and numbered sections with separate Results and Discussion sections. Manuscript must include a graphical abstract submitted as a separate file, four to five keywords immediately after the abstract, a brief Statement of Significance limited to 120 words, a Disclosures section before the references for conflicts of interest, and an AI declaration section before the references if AI was used in writing.
References References must use a numbered citation style with citations in square brackets. Reference list must be numbered in the order of appearance in the text and include all author names and the titles of all cited articles.
Figures & Tables Initial submission may be provided as a single file with figures, tables, and captions inserted in the text in the appropriate places. For final publication, each illustration must be submitted as a separate file with captions provided separately, and tables must be submitted as editable text rather than images.
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Recent Publications

Mechanically heterogeneous nanofibrous hydrogel drives Piezo1-mediated cell aggregation and collective migration

Haiyuan Song, Zhenhua Chao, Qian Guo, Yan Qi, Yixin Zhang, Xinlian Wang, Jiashuai Xu, Yue Liu, Weizhou Qiao, Lingyun Jia, Lulu Han

10.1016/j.actbio.2026.06.018
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Decorin Promotes Nascent Proteoglycan Retention in Cartilage Matrix by Strengthening Collagen II–Aggrecan Integration

Thomas Li, Gabriela Canziani, Yuchen Liu, Neil Patel, Biao Han, Mingyue Fan, Annie Porter, Bryan Kwok, Chao Wang, Qing Li, David E. Birk, Renato V. Iozzo, Irwin M. Chaiken, X. Lucas Lu, Robert L. Mauck, Lin Han

10.1016/j.actbio.2026.06.016
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Low-modulus hydrogels reduce scar formation in wound healing

Bingjie Fu, Huidi Meng, Min Liang, Xiaoqing Liu, Man Li, Xingpu Liu, Xiaowei Liu, Xiaofei Dong, Changyou Gao

10.1016/j.actbio.2026.06.017
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Advanced Extracellular Vesicle Therapeutics: From Molecular Engineering to Intelligent Devices

Xingyu Tao, Guangyue Zu, Jingcheng Su, Shuang Feng, Xianguang Ding, Renjun Pei

10.1016/j.actbio.2026.06.015
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Editorial Board

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10.1016/s1742-7061(26)00353-3
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Frequently asked questions

How long does it take to publish?

4 days submission to first decision; 40 days submission to decision after review; 126 days submission to acceptance; 1 day from acceptance to first online publication.

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What are the publication costs?

Open Access Article Publishing Charge (APC): USD 3,810 (excluding taxes). Subscription publication has no publication fee charged to authors.

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Research Topics

Bone Tissue Engineering Materials Electrospun Nanofibers in Biomedical Applications 3D Printing in Biomedical Research Nanoplatforms for cancer theranostics Tissue Engineering and Regenerative Medicine Orthopaedic implants and arthroplasty Nanoparticle-Based Drug Delivery Cellular Mechanics and Interactions RNA Interference and Gene Delivery Polymer Surface Interaction Studies Silk-based biomaterials and applications Dental materials and restorations Dental Implant Techniques and Outcomes Graphene and Nanomaterials Applications Hydrogels: synthesis, properties, applications Periodontal Regeneration and Treatments Osteoarthritis Treatment and Mechanisms Wound Healing and Treatments Magnesium Alloys: Properties and Applications biodegradable polymer synthesis and properties Calcium Carbonate Crystallization and Inhibition Human auditory perception and evaluation Mesenchymal stem cell research Educational Robotics and Engineering Diverse Scientific and Economic Studies