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Advances in Therapy

Advances in Therapy is an international, hybrid, peer-reviewed single-blind journal covering therapies, devices, and surgical techniques across all therapy areas. It emphasizes rapid publication, broad inclusion of scientifically sound research including positive, confirmatory, and negative data, and accepts work from clinical phase, real-world, and health economics outcomes studies for both international and country-specific audiences.

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Subject Medicine, Research & Experimental, Pharmacology & Pharmacy
Impact Factor 4
Quartile Q2
Open Access Type Hybrid
ISSN 0741-238X
eISSN 1865-8652
Invitation Only No
Cost Range Open access APC: £3090.00 GBP / $4990.00 USD / €3990.00 EUR; subscription publishing: no APC.

Submission Instructions

Advances in Therapy accepts the following article types. Click on an article type to view submission instructions.

Original Research

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required for Original Research articles. Abstract must not exceed 300 words. Abstract must be structured.
Manuscript Original Research articles should be around 4000 words. Main text must use the headings Introduction, Methods, Results, and Conclusion. Manuscript must include 3–10 keywords, 4–5 single-sentence key summary points using the structure "Why carry out this study?" and "What was learned from the study?", an acknowledgements section, and documentation of any Large Language Model use in the Methods section or another suitable section if there is no Methods section.
References References must use the Vancouver system. References must be numbered in the order cited, use Arabic numerals in square brackets in the text, list all authors if there are up to six, and list the first three authors followed by et al. if there are more than six.
Figures & Tables Tables must be included in the manuscript file, figure legends must appear in the manuscript after the references, and each figure must be uploaded as a separate file. Figures and tables must be cited in the text and numbered consecutively, tables must be editable rather than images, and figure parts must be labeled with lower-case Roman letters where applicable.
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Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required for Review articles. Abstract must not exceed 300 words. Abstract for a Review article does not need to be structured.
Manuscript There is no word limit for Review articles. Title must indicate the review format, such as systematic or narrative, and literature reviews should include a Methods section describing the search conduct, inclusion and exclusion dates, search terms, databases searched, and the numbers of records retrieved and discarded with reasons. Manuscript must include 3–10 keywords after the abstract, 4–5 single-sentence key summary points below the abstract, a statement identifying who conceived the article, performed the literature search and data analysis, and drafted and/or critically revised the work, and any use of a Large Language Model must be documented in the Methods section or another suitable section.
References References must use the Vancouver system. References must be cited in the text as Arabic numerals in square brackets, listed in citation order, include only works cited in the text, list all authors when there are up to six and the first three followed by et al. when there are more than six authors.
Figures & Tables Tables must be included in the manuscript file, figure legends must appear in the manuscript after the references, and each figure must be submitted as a separate file. Figures and tables must be cited in the text and numbered consecutively, tables must have a concise title and be provided in editable format, and figure legends must be brief self-contained explanations with all abbreviations, colors, and symbols explained.
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Narrative Review

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required for Narrative Reviews. Abstract must be no more than 300 words.
Manuscript The manuscript must include a title page, abstract, keywords, 4–5 key summary points, main text, acknowledgements, references, tables, and figure legends. The manuscript must include 3–10 keywords, 4–5 single-sentence key summary points, an acknowledgements section, and documentation of any Large Language Model use in the Methods section or another suitable section if there is no Methods section.
References References must use the Vancouver system. References must be cited in the text as Arabic numerals in square brackets, listed in citation order, include all authors when there are up to six, and list the first three authors followed by et al. when there are more than six.
Figures & Tables Each figure must be uploaded as a separate file, while tables are included in the manuscript file. Figure legends must be provided in the manuscript after the reference list rather than in the separate figure files, and tables must be submitted in an editable format such as Word rather than as images.
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Systemic Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required for this article type. Abstract must be no more than 300 words.
Manuscript Manuscript must include 3–10 keywords after the abstract, 4–5 single-sentence key summary points below the abstract, an acknowledgements section before the references, and documentation of any Large Language Model use in the Methods section or another suitable section if there is no Methods section.
References References must use the Vancouver system. References must include only works cited in the text, list all authors when there are up to six and the first three followed by et al. when there are more than six, use Arabic numerals in square brackets for in-text citations, and be ordered in the reference list according to citation sequence.
Figures & Tables Figures must be uploaded as separate files, while tables, figure legends, and the main manuscript content must be included in the separate manuscript file. Figures and tables must be cited in the text and numbered consecutively, figure legends must appear in the manuscript after the references rather than in the figure files, and tables must be provided in an editable format.
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Brief Reports

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required for Brief Reports. Abstract must not exceed 300 words. Abstract must be structured. Structured abstract must use the headings Introduction, Methods, Results, and Conclusion.
Manuscript Brief Reports should be around 2000–3000 words. Main text must use the headings Introduction, Methods, Results, and Conclusion. Manuscript must include 4–5 single-sentence key summary points below the abstract, 3–10 keywords after the abstract, an acknowledgements section before the references, and documentation of any Large Language Model use in the Methods section or another suitable section if there is no Methods section.
References References must use the Vancouver system. References must be numbered in the order cited, listed in that same sequence, cite all authors when there are up to six and the first three followed by et al. when there are more than six, and use Arabic numerals in square brackets for in-text citations.
Figures & Tables Tables must be included in the manuscript file, figure legends must appear in the manuscript after the references, and each figure must be uploaded as a separate file. Figures and tables must be cited in the text and numbered consecutively throughout.
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Case Series

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required for Case Series. Abstract must be up to 300 words.
Manuscript Case Series should be around 3000 words. Case Series must be structured as Abstract, Introduction, Case presentations, Discussion, Conclusion(s), Acknowledgements, and References. Manuscript must include 4–5 single-sentence key summary points below the abstract, and any use of a Large Language Model must be documented in the Methods section or another suitable part of the manuscript.
References References must use the Vancouver system. References must be numbered in text with Arabic numerals in square brackets, listed in citation order, and list all authors when there are up to six or the first three followed by et al. when there are more than six.
Figures & Tables Tables must be included in the manuscript file, while each figure must be submitted as a separate file and figure legends must appear in the manuscript after the references. Tables must be provided in an editable format rather than as images.
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Guidelines

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required for Guidelines. Abstract must be no more than 300 words.
Manuscript Guidelines should be around 10,000–15,000 words. Manuscript must include a title page, abstract, keywords, 4–5 key summary points, main text, acknowledgements, references, tables, and figure legends. Manuscript must include 3–10 keywords, 4–5 single-sentence key summary point bullets, an acknowledgements section containing the disclaimer "Springer Healthcare is not responsible for the validity of guidelines it publishes.", and disclosure of any Large Language Model use in the Methods section or another suitable section if no Methods section exists.
References References must use the Vancouver system. References must be numbered in the order cited, use Arabic numerals in square brackets in the text, list all authors when there are up to six and the first three followed by et al. when there are more than six, and include only works cited in the text.
Figures & Tables Figures must be uploaded as separate files, while tables are included in the manuscript file. Figure legends must be provided in the manuscript after the reference list, and tables must be supplied in an editable format such as Word rather than as images.
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Letters To The Editor

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is not mandatory for Letters To The Editor.
Manuscript Letters To The Editor should be around 1000 words. Letters To The Editor should comment on a recently published article in the journal. Key summary points are not mandatory.
References References must be supplied using the Vancouver system. References must be listed in the same order as their numbered citations in the text, with up to six authors listed in full and more than six listed as the first three followed by et al.
Figures & Tables Figures must be submitted as separate files, while tables must be included in the manuscript in editable format. Figure legends must be provided in the manuscript after the reference list, and tables must have a concise title with any abbreviations defined in table notes.
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Recent Publications

Brixadi for Stimulant Use Disorder: Evolving Pharmacologic Considerations and Clinical Implications

M. Farris Sawaya, Molly E. McNulty, Collin J. St. Germain, Ibraheem A. Hachem, Meissy S. Calix, Rhys M. Lormand, Nicholas J. E. McComb, Abdallah A. Abu Shehab, James Wrightson, Ahmed I. Anwar, Cy J. Fontenot, Alan D. Kaye, Kevin S. Murnane

10.1007/s12325-026-03772-4
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Design of a New Predictive Equation for the Induction Dose of Tacrolimus in Immediate Renal Transplantation

Olga Guillén-Martínez, Enrique Barrajón-Catalán, Daniel Martínez-Caballero Martínez, Leticia Soriano-Irigaray, Fernando Borrás-Rocher, Leonidas Cruzado-Vega, Alejandra Sabater-Belmar, Ana Cristina Murcia-López

10.1007/s12325-026-03739-5
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Comparative Cost-Effectiveness of Advanced Treatment Sequences for Moderately to Severely Active Ulcerative Colitis in Japan

Kazumasa Kamei, Miwa Enami, Hiroyuki Matsuda, Katsuya Yamagami, Yawen Dai, Masato Hoshi, Ernest H. Law, Akira Yuasa

10.1007/s12325-026-03757-3
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Effectiveness and Safety of Nefecon in Primary IgA Nephropathy Across Different Baseline Proteinuria Levels: A Real-World Study

Chahan Suolinge, Cai Dema, Xinyue Wu, Bijian Jiang, Chen Lu, Jing Li

10.1007/s12325-026-03784-0
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Assessment of the Value of Nivolumab Plus Ipilimumab for Treating Microsatellite Instability-High/Mismatch Repair Deficiency Metastatic Colorectal Cancer: Indirect Treatment Comparison and Cost-Effectiveness Analysis

Lytske J. Bakker, Katharina Nickel, Zoe Cheah, Elizabeth A. Sigworth, Bodille P. M. Blomaard, Reginald Villacorta, Lixian Jin, Kiran Davé, Claire L. Simons, Craig Bennison

10.1007/s12325-026-03787-x
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Frequently asked questions

How long does it take to publish?

The journal aims for a 2-week peer review, 3-4 weeks from acceptance to online, and reports a median of 2 days from submission to first decision.

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What are the publication costs?

Open access APC: £3090.00 GBP / $4990.00 USD / €3990.00 EUR. Subscription publishing: no APC.

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Research Topics

Diabetes Treatment and Management Asthma and respiratory diseases Rheumatoid Arthritis Research and Therapies Diabetes Management and Research Glaucoma and retinal disorders Retinal Diseases and Treatments Chronic Obstructive Pulmonary Disease (COPD) Research Blood Pressure and Hypertension Studies Biosimilars and Bioanalytical Methods Diabetes, Cardiovascular Risks, and Lipoproteins Psoriasis: Treatment and Pathogenesis Spondyloarthritis Studies and Treatments Ocular Surface and Contact Lens Medication Adherence and Compliance Inflammatory Bowel Disease Atrial Fibrillation Management and Outcomes Lipoproteins and Cardiovascular Health Lung Cancer Treatments and Mutations Dermatology and Skin Diseases Heart Failure Treatment and Management Health Systems, Economic Evaluations, Quality of Life Inhalation and Respiratory Drug Delivery Respiratory and Cough-Related Research Corneal surgery and disorders Bariatric Surgery and Outcomes

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