AP

Alimentary Pharmacology & Therapeutics

Alimentary Pharmacology & Therapeutics is a global pharmacology journal concerned with the effects of drugs on the human gastrointestinal and hepato-biliary systems, publishing a diverse range of topics often with immediate clinical impact. It is interested in therapies and diagnostics, including all aspects of translation from bench to bedside and clinical trials.

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Impact Factor 6.7
Quartile Q1
Open Access Type Hybrid
ISSN 0269-2813
eISSN 1365-2036
Invitation Only No
Cost Range FREE submission; authors can choose to publish open access after full peer-review

Submission Instructions

Alimentary Pharmacology & Therapeutics accepts the following article types. Click on an article type to view submission instructions.

Original Articles

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must use the headings Background, Aims, Methods, Results, and Conclusions.
Manuscript Main text should be approximately 12–20 double-spaced A4 pages at about 300 words per page, and the total word count excluding the abstract must be stated on the front page. Manuscript should include Introduction, Methods, Results, Discussion, and References. Manuscript must include 3–7 keywords and disclose any use of artificial intelligence generated content tools in the Methods or Acknowledgements section.
References References must be numbered consecutively in order of appearance, with in-text citations given as Arabic superscript numerals.
Figures & Tables Main text and figures should be submitted as separate files. Figures and tables must include concise, comprehensive legends that allow them to be understood without reference to the text.
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Systematic Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must use the headings Background, Aims, Methods, Results, and Conclusions.
Manuscript Manuscript must include abstract, introduction, methods, results, and conclusions, and the title must carry the appropriate article-type prefix such as 'Systematic review: ...'. Manuscript must include 3-7 keywords, an authorship statement including author contributions and guarantor identification, a statement that all authors approved the final version including the authorship list, the CRediT taxonomy, and any AI tool use described in the Methods or Acknowledgements.
References References may be submitted in any consistent style or format. References must be numbered consecutively in order of appearance and cited in the text using Arabic superscript numerals.
Figures & Tables The main text file should contain tables and figure legends, while figures should be submitted as separate files. Figures and tables must have concise, comprehensive legends and be understandable without reference to the text.
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Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must use the headings Background, Aims, Methods, Results, and Conclusions.
Manuscript Reviews must report the search strategy for selecting relevant literature, and the title must begin with the appropriate article-type prefix such as 'Review article:', 'Systematic review:', or 'Meta-analysis:'. Manuscript must include 3-7 keywords and transparently describe any use of artificial intelligence generated content tools in the Methods or Acknowledgements section.
References References may be submitted in any consistent style or format. References must be numbered consecutively in order of appearance, with in-text citations given as Arabic superscript numerals.
Figures & Tables Main text and figures should be submitted as separate files. Figures and tables must include concise, comprehensive legends that can be understood without reference to the text.
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Meta-Analyses

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must use the headings Background, Aims, Methods, Results, and Conclusions.
Manuscript Manuscript must include the required sections abstract, introduction, methods, results, and conclusions, and the title must carry the appropriate article-type prefix such as 'Meta-analysis: ...'. Manuscript must include 3–7 keywords and a transparent declaration of any artificial intelligence generated content tool use in the Methods or Acknowledgements section.
References References may be submitted in any consistent style or format. References must be numbered consecutively in order of appearance, with in-text citations given as Arabic superscript numerals in consecutive order.
Figures & Tables Figures should be submitted separately from the main text file, while tables are included with the main text file. Figures and tables must have concise, comprehensive legends and be understandable without reference to the text.
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Clinical Trials

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required for Clinical Trials. The abstract must not exceed 250 words. The abstract must be structured. The abstract must use the headings Background, Aims, Methods, Results, and Conclusions, and include the trial register name and clinical trial registration number at the end of the abstract and the registration number at the end of the final line of the Conclusions.
Manuscript The manuscript must contain abstract, introduction, methods, results, and conclusions, and the title must begin with the prefix 'Clinical trial:'. The manuscript must include 3–7 keywords, an Authorship Statement identifying the guarantor, specific author contributions, and approval by all authors, a CRediT contributor roles taxonomy, disclosure of any AI-generated content tool use in the Methods or Acknowledgements section, the trial registry details and registration number in the Methods section, the power of the study design, and any protocol deviations in the Methods section.
References References must be numbered consecutively in order of appearance, cited in the text using Arabic superscript numerals in consecutive order, and journal title abbreviations must follow Chemical Abstracts practice.
Figures & Tables The main text file should be submitted separately from figures, while the manuscript may contain text, figures, and tables together or as separate files. Figures and tables must have concise but comprehensive legends and be understandable without reference to the text, and tables must be supplied as editable files rather than images.
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Consensus Guidelines

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required for Consensus Guidelines. The structured abstract must not exceed 250 words. The abstract must be structured. The structured abstract must include the headings Background, Aims, Methods, Results, and Conclusions and include the key recommendations.
Manuscript The manuscript must include the required sections abstract, introduction, methods, results, and conclusions. The manuscript must include 3–7 keywords, an Authorship Statement identifying the guarantor and specific author contributions with confirmation that all authors approved the final version including the authorship list, the CRediT contributor roles taxonomy, and transparent disclosure of any AI-generated content tool use in the Methods or Acknowledgements section.
References References may be submitted in any consistent style or format. References must be numbered consecutively in order of appearance and cited in the text using Arabic superscript numerals in consecutive order.
Figures & Tables The main text file should be submitted separately from figures. Figures and tables must have legends.
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Letters To The Editor

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Manuscript must not exceed 500 words. Letter must discuss a paper already published in the journal, preferably within the last 18–24 months. Keywords are required, with 3–7 keywords to be provided, and any use of an artificial intelligence generated content tool must be disclosed in the Methods or Acknowledgements section.
References References are limited to a maximum of 10. References must be numbered consecutively in order of appearance, with in-text citations given as Arabic superscript numerals.
Figures & Tables A maximum of one table or figure may be included. The manuscript may include text, figures, and tables in one editable file or as separate files, although the main text file and figures should be submitted separately. Figures and tables must have concise, comprehensive legends and be understandable without reference to the text.
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Recent Publications

Editorial: Optimal Treatment for Older Patients With Inflammatory Bowel Disease: How to Detect and Manage Frailty? Authors' Reply

A. B. Fons, V. E. R. Asscher, S. P. Mooijaart, P. W. J. Maljaars

10.1111/apt.70660
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Letter: Early Inflammatory Benefit Is Not Yet Equivalent to Durable Surgical Advantage After Colectomy in Colonic Crohn's Disease

Jiacheng Li

10.1111/apt.70700
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A Care Pathway for the Treatment of IBD Reduces Healthcare Costs and Is Cost‐Effective: Results of the Multicentre IBD Value Study

Elyke H. Visser, Martijn. A. Oude Voshaar, Reinier C. A. van Linschoten, Alexander G. L. Bodelier, Claire Fitzpatrick, Vincent de Jonge, Hestia Vermeulen, K. Evelyne Verweij, Sanne van der Wiel, Daniëlle van der Horst, C. Janneke van der Woude, R. L. West, D. van Noord

10.1111/apt.70690
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Correlation of Bile Acid Dynamics to Bulevirtide Response and Disease Severity in Patients With Hepatitis D

Marlene Hintersteininger, Michael Schwarz, Philipp Schwabl, Lukas Hartl, Lorenz Balcar, Benedikt Silvester Hofer, Georg Kramer, Christian Sebesta, Paul Thöne, Patrik Attalla, Michael Gschwantler, Michael Trauner, Mattias Mandorfer, Thomas Reiberger, Mathias Jachs

10.1111/apt.70675
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Editorial: Gene Silencing Therapy for a New Era of Pancreatitis Prevention. Authors' Reply

Rohit Loomba, Enrique de‐Madaria, Elham Afghani, Vikesh K. Singh, Nicholas J. Leeper

10.1111/apt.70692
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Frequently asked questions

How long does it take to publish?

2 days submission to first decision (median). 11 days submission to first decision on average in 2024 excluding Letters, Editorials and Replies. 7 weeks from acceptance to publication in an online issue. Final corrected proofs are published 16-24 days after acceptance.

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What are the publication costs?

FREE submission. Authors can choose to publish open access after full peer-review.

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Research Topics

Helicobacter pylori-related gastroenterology studies Liver Disease Diagnosis and Treatment Gastroesophageal reflux and treatments Inflammatory Bowel Disease Microscopic Colitis Eosinophilic Esophagitis Gastrointestinal motility and disorders Hepatitis C virus research Liver Disease and Transplantation Hepatitis B Virus Studies Gastric Cancer Management and Outcomes Liver Diseases and Immunity Celiac Disease Research and Management Esophageal and GI Pathology Inflammatory mediators and NSAID effects Hepatocellular Carcinoma Treatment and Prognosis Veterinary medicine and infectious diseases Alcohol Consumption and Health Effects Pregnancy and Medication Impact Colorectal Cancer Screening and Detection Diet, Metabolism, and Disease Gastrointestinal disorders and treatments Diet and metabolism studies Organ Transplantation Techniques and Outcomes Clostridium difficile and Clostridium perfringens research