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Alzheimers Research & Therapy

Alzheimer's Research & Therapy is an open access journal focused on translational research into dementia and neurodegenerative diseases, with particular emphasis on Alzheimer's disease. Affiliated with Alzheimer’s Disease International, it publishes basic research, clinical trials, drug discovery and development research, epidemiologic studies, reviews, viewpoints, commentaries, debates, reports, and research articles.

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Subject Clinical Neurology, Neurosciences
Impact Factor 7.6
Quartile Q1
Open Access Type Open
eISSN 1758-9193
Invitation Only No
Cost Range APC: £3090.00 GBP / $4390.00 USD / €3490.00 EUR, plus VAT or local taxes where applicable.

Submission Instructions

Alzheimers Research & Therapy accepts the following article types. Click on an article type to view submission instructions.

Research Articles

Cover Letter A cover letter is required. Cover letter must explain why the manuscript should be published in Alzheimer's Research & Therapy, address any issues relating to journal policies, declare any potential competing interests, confirm all authors approved the submission, and confirm the manuscript has not been published or submitted elsewhere.
Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be structured. Abstract must include the headings Background, Methods, Results, Conclusions, and Trial registration, and the Limitations section must be summarized for human studies and animal studies exploring new treatments.
Manuscript Manuscript must include Methods, Discussion, Conclusions, an explicit Limitations section placed between the Discussion and the Conclusions, and a Declarations section. Manuscript must include three to ten keywords, a Declarations section with all required subheadings, and any use of a Large Language Model must be documented in the Methods section or a suitable alternative section.
References References must follow Vancouver style. Only published or in-press articles, clinical trial registration records, abstracts, and publicly available preprints may be cited, unpublished abstracts, unpublished data, and personal communications must be excluded from the reference list, web links and URLs must appear as numbered references in the reference list, and journal abbreviations must follow Index Medicus/MEDLINE.
Figures & Tables Figure titles and legends must be provided in the main manuscript rather than in the graphic file, tables shorter than one page may be placed within the manuscript, and tables longer than one page may be placed at the end of the document with their position indicated in the text. Figures must be numbered in the order first mentioned and multi-panel figures submitted as a single composite file, while tables must be numbered and cited sequentially and must not be embedded as figures or spreadsheet files.
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Reviews

Cover Letter A cover letter is required. Cover letter must explain why the manuscript should be published in Alzheimer's Research & Therapy, explain any issues relating to journal policies, declare any potential competing interests, confirm that all authors approved submission, confirm the manuscript has not been published or submitted elsewhere, and name the special issue if applicable.
Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be structured. Abstract must include background, main body of the abstract, and short conclusion.
Manuscript Reviews should be approximately 4000 words. Manuscript must include a title page, Background section, Conclusions section, and a Declarations section with the subheadings Ethics approval and consent to participate, Consent for publication, Availability of data and materials, Competing interests, Funding, Authors' contributions, Acknowledgements, and Authors' information, using 'Not applicable' for any non-relevant declaration subheading. Manuscript must include three to ten keywords, a list of abbreviations if abbreviations are used, and a Declarations section.
References Reviews should include 50 references. References must use Vancouver style. Only articles, clinical trial registration records, and abstracts that are published, in press, or publicly available as e-prints or preprints may be cited; unpublished abstracts, unpublished data, and personal communications must not appear in the reference list; journal abbreviations must follow Index Medicus/MEDLINE; and web links or URLs must be cited by reference number in the reference list with the site title, full URL, and access date.
Figures & Tables Tables less than one page may be placed within the manuscript, tables larger than one page may be placed at the end of the document with their intended location cited in the text, figure titles and legends must be provided in the main manuscript rather than in the graphic file, and figures must be uploaded separately. Figures must be numbered in order of first mention and multi-panel figures submitted as single composite files, while tables must be numbered and cited in sequence and created using the word processor's Table object rather than embedded as figures or spreadsheet files.
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Mini Review

Cover Letter A cover letter is required. Cover letter must explain why the manuscript should be published, address any issues relating to journal policies, declare any potential competing interests, confirm all authors approved the submission, confirm the manuscript has not been published or submitted elsewhere, and name the special issue if applicable.
Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be structured. Abstract must include Background, Main body of the abstract, and Short conclusion.
Manuscript Mini Review must be no more than 1000 words excluding references but including the abstract. Manuscript must include a title page, abstract, keywords, Background, Main text, Conclusions, and a Declarations section. Manuscript must include three to ten keywords, one figure, a Declarations section with the subheadings Competing interests, Funding, Authors' contributions, Acknowledgements, and Authors' information (optional), use 'Not applicable' for irrelevant declarations sections, and provide a list of abbreviations if abbreviations are used.
References References must use Vancouver style. Only published or in-press articles, clinical trial registration records, abstracts, and publicly available preprints may be cited, unpublished abstracts, unpublished data, and personal communications must not appear in the reference list, journal abbreviations must follow Index Medicus/MEDLINE, and web links or URLs must be numbered and included in the reference list in full with site title, URL, and access date.
Figures & Tables Mini Review must include one figure. Figure titles and legends must be included in the main manuscript rather than in the graphic file, tables shorter than one page may be placed within the manuscript, and larger tables may be placed at the end of the document. Figures must be numbered in order of first mention and multi-panel figures submitted as a single composite file.
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Correspondence

Cover Letter A cover letter is required. Cover letter must explain why the manuscript should be published in Alzheimer's Research & Therapy, address any issues relating to journal policies, declare any potential competing interests, confirm all authors approved submission, and confirm the manuscript has not been published or submitted elsewhere.
Abstract Abstract requirements are not specified.
Manuscript Correspondence manuscripts must include a 'Declarations' heading containing Ethics approval and consent to participate, Consent for publication, Availability of data and materials, Competing interests, Funding, Authors' contributions, Acknowledgements, and optionally Authors' information, with non-relevant sections retained and marked 'Not applicable'. The manuscript must include an Availability of data and materials statement and declarations for funding, authors' contributions, competing interests, and acknowledgements, with Authors' information optional.
References References must follow Vancouver style. Only published or in-press articles, clinical trial registration records, abstracts, and publicly available preprints may be cited, unpublished abstracts/data and personal communications must be excluded from the reference list, and URLs must be numbered and included in the reference list in full.
Figures & Tables Figure titles and legends must be provided in the main manuscript rather than in the graphic file, tables shorter than one page can be placed within the manuscript, and longer tables can be placed at the end with their intended location cited in the text. Figures and tables are not allowed in footnotes.
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Recent Publications

Plasma extracellular vesicle proteins biomarker for cerebral small vessel disease related cognitive impairment

Dan Yang, Pinyi Liu, Mengxi Han, Zhihong Ke, Yi Tan, Linjie Yu, Zheqi Hu, Chenglu Mao, Yue Cheng, Hao Zhang, Yun Zhang, Xiaolei Zhu, Yun Xu

10.1186/s13195-026-02078-5
View Publication

Cellular state heterogeneity underlying sex differences in Alzheimer’s disease based on single-cell transcriptome

Zhiyi Wu, Qinglong Tan, Fei Xue, Zhuotong Jiang, Hongyu Zhao, Yuting Zhang, Yiming Liu, Yu Zhang, Danli Ding, Hongping Chen, Yingqi Xu, Feng Li, Chunlong Zhang

10.1186/s13195-026-02081-w
View Publication

Clinical correlates of sleep profiles in dementia with Lewy bodies: a latent class approach

Léa Renard, Clément Aveneau, Karl Götze, Olivier Varnet, Alice Dieudonné, Claire Hourrègue, Emmanuel Cognat, Julien Dumurgier, Capucine Diard, Marie-Pia d’Ortho, Claire Paquet, Agathe Vrillon

10.1186/s13195-026-02059-8
View Publication

Comparative performance of semi-quantitative methods for amyloid deposition in preclinical autosomal dominant Alzheimer’s disease

Zhi Zhou, Jin Gao, Qi Wang, Qigeng Wang, Linwen Liu, Xiaojun Zhang, Can Li, Jiajin Liu, Yidan Wei, Shixiang Zhang, Ruimin Wang, Jianping Jia, Liping Fu

10.1186/s13195-026-02069-6
View Publication

Income dynamics and risk of early-onset dementia: a nationwide cohort study

Byung-Joon Ko, Yong-Moon Mark Park, Kyu-Na Lee, Kyungdo Han, Ga Eun Nam

10.1186/s13195-026-02067-8
View Publication

Frequently asked questions

How long does it take to publish?

Average time to first decision is within 5 weeks; submission to first decision (median) is 6 days.

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Is a cover letter required?

A cover letter is required and should explain why the manuscript should be published in Alzheimer's Research & Therapy, address any issues relating to journal policies, declare potential competing interests, confirm all authors approved the submission, confirm the work has not been published or submitted elsewhere, and identify the special issue if applicable. Authors may also suggest preferred or non-preferred peer reviewers in the cover letter.

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What are the publication costs?

An article processing charge applies for each accepted article. The current APC is £3090.00 GBP / $4390.00 USD / €3490.00 EUR, plus VAT or local taxes where applicable.

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Research Topics

Dementia and Cognitive Impairment Research Alzheimer's disease research and treatments Functional Brain Connectivity Studies Neuroinflammation and Neurodegeneration Mechanisms Neurological Disease Mechanisms and Treatments Intracerebral and Subarachnoid Hemorrhage Research Cholinesterase and Neurodegenerative Diseases Amyotrophic Lateral Sclerosis Research Cancer-related cognitive impairment studies Parkinson's Disease Mechanisms and Treatments Traumatic Brain Injury Research Tryptophan and brain disorders Cerebrospinal fluid and hydrocephalus Schizophrenia research and treatment Health Systems, Economic Evaluations, Quality of Life Neuroscience and Neuropharmacology Research Genetic Associations and Epidemiology Advanced Neuroimaging Techniques and Applications S100 Proteins and Annexins Neurogenesis and neuroplasticity mechanisms Computational Drug Discovery Methods Nutritional Studies and Diet Neurobiology of Language and Bilingualism Metabolomics and Mass Spectrometry Studies Intensive Care Unit Cognitive Disorders

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