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Alternatives to Laboratory Animals

ATLA is a peer-reviewed journal covering the development, validation, implementation and use of alternatives to laboratory animals in biomedical research and toxicity testing, including work focused on replacement, reduction and refinement of animal use.

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Impact Factor 3
Quartile Q2
Open Access Type Hybrid
ISSN 0261-1929
eISSN 2632-3559
Invitation Only No
Cost Range Article processing charges apply for hybrid open access, and institutional agreements or prepaid accounts may cover APCs.

Submission Instructions

Alternatives to Laboratory Animals accepts the following article types. Click on an article type to view submission instructions.

Research Papers

Cover Letter A cover letter must be included. The cover letter should indicate why the manuscript is suitable for publication.
Abstract A structured abstract is required. The abstract must be up to 250 words. The abstract must be structured.
Manuscript Articles should normally contain 2000-3000 words. Manuscripts should normally contain the following sections: structured abstract, introduction, materials/methods/procedures, results, discussion, conclusion, acknowledgements, declaration of conflicting interests, funding, references, tables, and figures. The manuscript must include 5-10 keywords and a section headed 'Statements and Declarations' containing each required subheading even when not applicable, with 'Not applicable' stated under headings that do not apply, and AI usage should be disclosed in the Acknowledgements or Methodology section when required by the journal's AI use policy.
References References must follow the Sage Vancouver reference style. Every in-text citation must have a corresponding reference list entry and vice versa, with identical spelling and year in corresponding citations.
Figures & Tables Figures, charts, and tables created in Word should be included in the main text, while figures and other files created outside Word should be submitted separately with a placeholder note in the text for separately submitted figures. Tables must be labeled as tables, include a number, title, and header row and/or column, be editable within Word rather than images, and figures must be numbered consecutively and include a number and title.
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Review Articles

Cover Letter A cover letter is required. Cover letter should indicate why the manuscript is suitable for publication.
Abstract A structured abstract is required. Abstract must be up to 250 words. Abstract must be structured.
Manuscript Review Articles may be up to 4500 words. Manuscripts should normally contain sections for structured abstract, introduction, materials/methods/procedures, results, discussion, conclusion, acknowledgements, declaration of conflicting interests, funding, references, tables, and figures. Manuscript must include 5–10 keywords and a 'Statements and Declarations' section at the end with each required subheading included even when not applicable, and AI usage should be disclosed in the Acknowledgements or Methodology section when required by the journal's AI use policy.
References References must follow the Sage Vancouver style. Every in-text citation must have a corresponding reference list entry and vice versa, with identical spelling and year in corresponding citations.
Figures & Tables Figures, charts, and tables created in Word should be included in the main text, while figures and other files created outside Word should be submitted separately with a placeholder note in the text for separately submitted figures. Tables must be labeled and numbered with a title, include a header row and/or column, be editable rather than images, and figures must be numbered consecutively and include a number and title.
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Letters

Cover Letter A cover letter must be included. The cover letter should indicate why the manuscript is suitable for publication.
Abstract A structured abstract is required. The abstract must be no more than 250 words. The abstract must be structured.
Manuscript Letters should normally contain 2000-3000 words. Manuscripts should normally contain a structured abstract, introduction, materials/methods/procedures, results, discussion, conclusion, acknowledgements, declaration of conflicting interests, funding, ethical approval, informed consent, references, tables, and figures. The manuscript must include 5-10 keywords and a section headed 'Statements and Declarations' at the end of the article with each required subheading included even when not applicable, and AI usage should be disclosed in the Acknowledgements or Methodology section when required by the journal's AI use policy.
References References must follow the Sage Vancouver reference style. Every in-text citation must have a corresponding reference list entry and vice versa, and corresponding citations must have identical spelling and year.
Figures & Tables Figures, charts, and tables created in Word should be included in the main text, while figures and other files created outside Word should be submitted separately with a placeholder note in the running text. Tables must be editable within Word and not included as images, and figures and tables must be numbered consecutively and include a title.
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Recent Publications

Galleria mellonella as an invertebrate screening model for biocompatibility and in vivo functionality testing of imaging contrast agents

Timen Mooren, Birger Tielemans, Agustin Reséndiz-Sharpe, Greetje Vande Velde

10.1177/02611929261460795
View Publication

Data-driven science, ethics and risk: Building knowledge of key ethics–risk intersections relevant to public sector decision-making

Yadvinder Bhuller, Marc Avey, P. Charukeshi Chandrasekera, David K. Lee, Ranjana Sharma, Benjamin Woodman, Valerie H. Taylor

10.1177/02611929261458967
View Publication

Conference Diary

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10.1177/02611929261456544
View Publication

2026 Michael Balls Award

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10.1177/02611929261456545
View Publication

Replacing immunisation-dependent antibody reagent production: Challenges under the UK Replacing Animals in Science 2025 strategy

Alison C. Gray, Kevin C. Gough

10.1177/02611929261455318
View Publication

Frequently asked questions

How long does it take to publish?

Median time to first decision is 3 days, time in peer review is 47 days, submission to acceptance is 104 days, and acceptance to online publication is 48 days.

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Is a cover letter required?

A cover letter is required and should explain why the manuscript is suitable for publication. If writing assistance or third-party submission is involved, this must also be stated in the covering letter.

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What are the publication costs?

Article processing charges apply for hybrid open access, and institutional agreements or prepaid accounts may cover APCs.

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Research Topics

Animal testing and alternatives Human auditory perception and evaluation Educational Robotics and Engineering Diverse Scientific and Economic Studies Educational Reforms and Innovations Computational Drug Discovery Methods Carcinogens and Genotoxicity Assessment Effects and risks of endocrine disrupting chemicals 3D Printing in Biomedical Research Legal Cases and Commentary Environmental Toxicology and Ecotoxicology Legal case studies and regulations Immunotoxicology and immune responses Pesticide Exposure and Toxicity Veterinary Pharmacology and Anesthesia Animal Genetics and Reproduction Viral Infectious Diseases and Gene Expression in Insects Pharmacogenetics and Drug Metabolism Animal Behavior and Welfare Studies Contact Dermatitis and Allergies Biomedical Ethics and Regulation Transgenic Plants and Applications Pluripotent Stem Cells Research Animal and Plant Science Education Mechanical Circulatory Support Devices