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Biologics

Biologics: Targets and Therapy is an international, peer-reviewed, open access journal focused on the pathophysiological rationale for and clinical application of biologic agents and biosimilars in autoimmune diseases, cancers, and other pathologies with identifiable molecular targets. Topics include gene therapy, cell therapy, antibody-based therapy, blood components, vaccines, hormones, cytokines and growth factors, toxins, and peptides. The journal publishes original research, reviews, basic science, clinical studies, and commentaries, does not accept study protocols, no longer considers meta-analyses, and considers case reports only when they make a valuable and original contribution to the literature.

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Impact Factor 3.4
Quartile Q2
Open Access Type Open
ISSN 1177-5475
eISSN 1177-5491
Invitation Only No
Cost Range Invited reviews are exempt from paying any publication processing fee.

Submission Instructions

Biologics accepts the following article types. Click on an article type to view submission instructions.

Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 300 words. Reviews commonly use an unstructured abstract.
Manuscript Manuscript must include the sections Introduction, Material and Methods, Results, Discussion, and Conclusions. Manuscript must include 3-6 keywords, and the abstract must be unstructured in one paragraph outlining the purpose of the paper, results obtained, and conclusions.
References References must follow American Medical Association (AMA) style. References must be cited sequentially in superscript numerals, numbered in citation order, use PubMed journal abbreviations, list all authors when there are six or fewer, and list the first three authors followed by "et al." when there are more than six.
Figures & Tables Figures must be provided separate from the manuscript, while tables may be included in the manuscript or submitted as separate files. Figures must not be pasted into the manuscript and tables must be submitted in editable format rather than as images.
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Invited Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 300 words. Abstract must be unstructured and presented in one paragraph.
Manuscript Manuscript must include the sections Introduction, Material and Methods, Results, Discussion, and Conclusions. Manuscript must include 3–6 keywords, and any use of AI must be acknowledged in the paper.
References References must follow American Medical Association (AMA) style. References must be cited sequentially in superscript Arabic numerals, numbered in citation order, use PubMed journal abbreviations, list all authors when there are six or fewer, and list the first three authors followed by et al. when there are more than six.
Figures & Tables Figures must be provided separate from the manuscript, while tables may be included in the manuscript or submitted as separate files. Figures must not be pasted into the manuscript, and tables must be submitted in editable format rather than as images.
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Original Research Papers

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required for Original Research Papers. Abstract must not exceed 300 words. Abstract must be structured.
Manuscript Manuscript typically includes Abstract, Introduction, Methods, Results, Discussion, and Conclusion sections. Manuscript must include 3 to 6 keywords, and authors must acknowledge the use of AI in the paper.
References References must follow American Medical Association (AMA) style. References must be cited sequentially in the text, tables, and legends using superscript Arabic numerals, numbered in the reference list in citation order, with PubMed journal abbreviations and all authors listed for six or fewer authors or the first three followed by "et al." for more than six.
Figures & Tables Figures must be provided separate from the manuscript, while tables may be provided within the manuscript or as separate files. Figures must not be pasted into the manuscript, tables must be submitted in editable format rather than as images, and both figures and tables must include legends or keys when needed to explain labels, symbols, or formatting.
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Meta-Analyses

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 300 words. Abstract must be unstructured and presented in one paragraph.
Manuscript Manuscript must include the sections Introduction, Material and Methods, Results, Discussion, and Conclusions. Manuscript must include 3 to 6 keywords, and authors must acknowledge the use of AI in the paper.
References References must follow American Medical Association (AMA) style. References must be cited sequentially in superscript Arabic numerals, listed in citation order, use PubMed journal abbreviations, list all authors when there are six or fewer, and list the first three authors followed by “et al.” when there are more than six.
Figures & Tables Figures must be uploaded separately from the manuscript, while tables may be included within the manuscript or submitted as separate files. Figures and tables must be cited in the text, figures must not be pasted into the manuscript, and tables must be submitted in editable format rather than as images.
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Case Reports

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 300 words. Abstract must be unstructured and presented in one paragraph.
Manuscript Case Report must describe a single patient case and include detailed information on the patient's symptoms, signs, diagnosis, treatment, and follow-up. Manuscript must include 3 to 6 keywords.
References References must follow American Medical Association (AMA) style. References must be cited sequentially in the text, tables, and legends using superscript Arabic numerals, numbered in citation order in the reference list, with PubMed journal abbreviations and all authors listed for six or fewer authors or the first three followed by "et al." for more than six authors.
Figures & Tables Figures must be provided separate from the manuscript, while tables may be included in the manuscript or submitted as separate files. Figures and tables must be cited in the text, figures must not be pasted into the manuscript, tables must be editable rather than images, and legends or keys must identify any labels, symbols, or indicators used.
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Recent Publications

Vunakizumab for IL-17A–Mediated Diseases: A Review in Psoriasis and Spondyloarthritis

Hongzhuo Yan, Yu Chen, Yali Song, Min Yan, Kexiang Yan

10.2147/btt.s500475
View Publication

Long-Term TIE2 Inhibition in a TEK-Mutated Venous Malformation: A 3-Year Clinical Experience

Paloma Triana, Elena Marín, Covadonga Mendieta, Lucía Fernández, Lara Rodriguez-Laguna, Juan Lopez-Gutierrez

10.2147/btt.s606831
View Publication

Rapid Resolution of Psoriasis Following Low-Dose Interleukin-2 Monotherapy: A Case Report

Doudou Ma, Zhanguo Li

10.2147/btt.s595201
View Publication

Vunakizumab and Acitretin for Elderly Refractory Generalized Pustular Psoriasis: A Case Report and Comprehensive Literature Review

Shilin Deng, Yu Jiang, Wei Li, Zhirong Shu, Tingnan Chen, Jingyao Liang, Xibao Zhang

10.2147/btt.s592069
View Publication

MicroRNA-661 Suppresses Proliferation and Migration of Pulmonary Artery Smooth Muscle Cells and Endothelial Cells by Targeting CCND2

Liyang Jiang, Aixiang Yang, Jun Liu, Jie Zhou

10.2147/btt.s592879
View Publication

Frequently asked questions

How long does it take to publish?

Accelerated Publication; rapid reporting of original research, reviews, basic science, clinical studies and commentaries.

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Is a cover letter required?

A point-by-point covering letter is required when submitting a revised manuscript after editorial review.

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What are the publication costs?

Invited reviews are exempt from paying any publication processing fee.

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Research Topics

Rheumatoid Arthritis Research and Therapies Monoclonal and Polyclonal Antibodies Research Biosimilars and Bioanalytical Methods Psoriasis: Treatment and Pathogenesis Systemic Lupus Erythematosus Research Spondyloarthritis Studies and Treatments Inflammatory Bowel Disease Chronic Lymphocytic Leukemia Research Lung Cancer Treatments and Mutations Autoimmune and Inflammatory Disorders Research Immunotherapy and Immune Responses Colorectal Cancer Treatments and Studies HER2/EGFR in Cancer Research CAR-T cell therapy research Autoimmune Bullous Skin Diseases Asthma and respiratory diseases Microscopic Colitis Cancer Treatment and Pharmacology Cancer Immunotherapy and Biomarkers Multiple Sclerosis Research Studies Platelet Disorders and Treatments Chronic Myeloid Leukemia Treatments T-cell and B-cell Immunology Acute Lymphoblastic Leukemia research Urticaria and Related Conditions