Overview Submission Instructions Recent Publications Frequently Asked Questions Research Topics

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Cancer Letters

Cancer Letters is an international journal providing a forum for original and pertinent contributions in cancer research. It considers full-length articles and Mini Reviews in the broad area of basic and translational oncology, with special issues highlighting topical areas in cancer research. Areas of interest include molecular genetics and cell biology of cancer, radiation biology, molecular pathology, hormones and cancer, viral oncology, metastasis, chemoprevention, and experimental therapeutics including targeted therapies for personalized cancer medicine.

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Subject Oncology

Impact Factor 10.1

Quartile Q1

Open Access Type Hybrid

ISSN 0304-3835

eISSN 1872-7980

Invitation Only No

Cost Range Open Access APC: USD 4,710 (excluding taxes). Subscription: no publication fee charged to authors.

Submission Instructions

Cancer Letters accepts the following article types. Click on an article type to view submission instructions.

Original Research Articles

Cover Letter Cover Letter requirements are not specified.

Abstract Abstract must not exceed 250 words.

Manuscript Original Research Articles should be between 3000 and 3500 words. Manuscripts should be divided into clearly defined sections using headings. Manuscripts must include 1 to 7 English keywords, provide 3 to 5 article highlights as a separate editable file, complete the declarations document, and add a generative AI statement in a new section before the references if AI was used in manuscript preparation.

References References may be submitted in any citation style or format as long as the style is consistent. References must include author names, source title, article or chapter title, year, and volume, article number, or page range where applicable, and every in-text citation must appear in the reference list and vice versa.

Figures & Tables Figures must be uploaded as separate files, while tables must be submitted as editable text. All figures and tables must be cited in the text, numbered consecutively in order of appearance, and provided with captions.

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Review Articles

Cover Letter Cover Letter requirements are not specified.

Abstract Abstract must not exceed 250 words.

Manuscript Manuscript should not exceed about 5000 words, excluding references. Manuscript should be divided into clearly defined sections using headings. Manuscript must include 1 to 7 English keywords, provide article highlights as a separate editable file with 3 to 5 bullet points of up to 85 characters each, and add a generative AI declaration in a new section before the references if such tools were used in manuscript preparation.

References Reference list should include no more than 100 references. References may be submitted in any consistent style or format. References must include author names, source title, article or chapter title, year, and volume with article number or pagination where applicable.

Figures & Tables Figures must be uploaded as separate files, while tables must be submitted as editable text. All figures and tables must be cited in the text, numbered in order of appearance, and include captions.

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Mini Reviews

Cover Letter Cover Letter requirements are not specified.

Abstract Abstract should not be included.

Manuscript Manuscript must be 1,500 words or less. Manuscript should be divided into sections when applicable, including Introduction, Materials and Methods, and Results and Discussion. Authors must provide 1 to 7 English keywords, submit 3 to 5 article highlights as a separate editable file, and include any generative AI use statement in a new section before the references list.

References References may be in any consistent style or format at submission. References must include author names, source title, article or chapter title, year, and volume and page or article number details where applicable.

Figures & Tables Tables must be submitted as editable text and figures must be supplied as separate files along with the manuscript. All tables and figures must be cited in the text, numbered in order of appearance, and accompanied by captions.

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Short Articles

Cover Letter Cover Letter requirements are not specified.

Abstract Abstract must not exceed 250 words.

Manuscript Manuscript should be divided into clearly defined sections covering all essential elements using headings. Manuscript must include 1 to 7 English keywords, article highlights of 3 to 5 bullet points submitted as a separate editable file, and a generative AI declaration in a new section before the references list if such tools were used in manuscript preparation.

References Short Articles should include no more than 15 references. References may be in any consistent style at submission and must include author names, source title, article or chapter title, year, and volume and page or article numbers where applicable.

Figures & Tables Short Articles should include no more than 2 tables or figures. Figures must be uploaded as separate files, while tables must be submitted as editable text. All figures and tables must be cited in the manuscript text, numbered consecutively in order of appearance, and include captions.

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Letters To The Editor

Cover Letter Cover Letter requirements are not specified.

Abstract Abstract is not required for Letters To The Editor.

Manuscript Letters To The Editor must be 1,500 words or less. Manuscripts should be divided into clearly defined sections covering all essential elements using headings. The manuscript must include 1 to 7 English keywords, article highlights of 3 to 5 bullet points, a declarations section before the references if generative AI was used in manuscript preparation, and acknowledgements in a separate section directly before the reference list.

References Letters To The Editor should include no more than 15 references. References may be in any consistent style at submission and must include author names, source title, article or chapter title, year, and volume and page or article number where applicable.

Figures & Tables Letters To The Editor should include no more than 2 tables or figures. Figures must be uploaded as separate files, while tables must be submitted as editable text. All figures and tables must be cited in the manuscript text, numbered consecutively in order of appearance, and include captions.

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Research Letters

Cover Letter Cover Letter requirements are not specified.

Abstract Abstract must not exceed 250 words. Abstract should be unstructured and concise enough to stand alone.

Manuscript Manuscript should be divided into clearly defined sections with headings. Manuscript must include 1 to 7 English keywords, provide article highlights as a separate editable file with 3 to 5 bullet points of no more than 85 characters each, and include a generative AI declaration in a new section before the references if such tools were used in manuscript preparation.

References References may be submitted in any consistent style or format. References must consistently include core bibliographic details, any abstract citations must be given in full, web references must include the full URL and access date, data references must be marked with [dataset], and preprints must be clearly identified.

Figures & Tables Figures must be uploaded as separate files, while tables must be submitted as editable text. All figures and tables must be cited in the text, numbered consecutively, and accompanied by captions, and tables must not be submitted as images.

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Recent Publications

Reactive oxygen species define leukemia stem cell identity in pediatric acute myeloid leukemia

Maddalena Benetton, Ambra Da Ros, Alberto Peloso, Giorgia Longo, Sara Perpinello, Chiara Frasson, Tiago Branco Fonseca, Elena Varotto, Silvia Bresolin, Claudia Tregnago, Luca Scorrano, Benjamin J. Huang, Soheil Meshinchi, Franco Locatelli, Martina Pigazzi

10.1016/j.canlet.2026.218866

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Targeting the Metabolic-Immune Regulator SLC35F6 Enhances Temozolomide and Anti-PD-L1 Therapy in Glioma

Pengpeng Lu, Wei Wang, Bing Lu, Shijie Xu, Feng Wang, Liang Han, Ziheng Wang, Jianfei Huang

10.1016/j.canlet.2026.218867

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When RNA Wears a Sugar Coat: Emerging Biology and Cancer Relevance of GlycoRNA

Tingju Ren, Zhuoqun Lin, Wenrui Xie, Ruizi Peng, Lingfang Wang

10.1016/j.canlet.2026.218878

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Targeting p300/CBP destabilizes HIF-2α and suppresses tumor growth in cell and animal models of clear cell renal cell carcinoma

Rushaniya Fazliyeva, Alexey Matveev, Ruslan Smetanin, Ilia Fedorov, Kathy Q. Cai, Alexander Kutikov, Robert G. Uzzo, Andrew Andrews, Peter Makhov, Vladimir M. Kolenko

10.1016/j.canlet.2026.218876

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Rapid Manufactured CAR-T Cells enriched for CD45RA-negative T cells Exhibit Superior Persistence Compared to Conventional CAR-T Therapy

Xuying Pei, Meng Lv, Xiaozheng Zhao, Zhuojun Liu, Luhan Deng, Zhipeng Zhou, Yanping Ding, Jing Liu, Leping Zhang, Qian Jiang, Xiaohui Zhang, Xinan Lu, Ting He, Xiaojun Huang, Xiangyu Zhao

10.1016/j.canlet.2026.218865

View Publication

Frequently asked questions

How long does it take to publish?

3 days from submission to first decision; 30 days from submission to decision after review; 92 days from submission to acceptance; 2 days from acceptance to first online publication for papers published online.

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What are the publication costs?

Open Access APC: USD 4,710 excluding taxes. Subscription option: no publication fee charged to authors.

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Research Topics

Cancer, Hypoxia, and Metabolism Cancer-related Molecular Pathways Diverse Scientific and Economic Studies Human auditory perception and evaluation RNA modifications and cancer Carcinogens and Genotoxicity Assessment Cancer Cells and Metastasis Educational Robotics and Engineering Epigenetics and DNA Methylation Cancer-related molecular mechanisms research MicroRNA in disease regulation Cell death mechanisms and regulation Genomics, phytochemicals, and oxidative stress DNA Repair Mechanisms Immunotherapy and Immune Responses Estrogen and related hormone effects Drug Transport and Resistance Mechanisms Ubiquitin and proteasome pathways Cancer Genomics and Diagnostics Cancer-related gene regulation Pancreatic and Hepatic Oncology Research Cancer Immunotherapy and Biomarkers Cancer Research and Treatments Cell Adhesion Molecules Research RNA Interference and Gene Delivery

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