Overview
Submission Instructions
Recent Publications
Frequently Asked Questions
Research Topics
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CA
Clinical and Translational Science (CTS) publishes original research that bridges laboratory discoveries with the diagnosis and treatment of human disease. It is the official open access journal of the American Society for Clinical Pharmacology and Therapeutics.
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Impact Factor
2.8
Quartile
Q2
Open Access Type
Open
ISSN
1752-8054
eISSN
1752-8062
Invitation Only
No
Cost Range
$3,990 USD / £3,030 GBP / €3,400 EUR APC; 19% discount for American Society for Clinical Pharmacology and Therapeutics members; waived for Book Review, Commentary, and Perspective.
Submission Instructions
Clinical and Translational Science accepts the following article types. Click on an article type to view submission instructions.
Article
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract is required for Article manuscripts. Abstract must be 250 words. Abstract must be unstructured.
Manuscript
Article manuscripts must not exceed 4,000 words. The body must use the headings Introduction, Methods, Results, and Discussion and also include Acknowledgements, Study Highlights after the Discussion, Author Contributions before the References, References, Figure Legends, and Tables. A Study Highlights section under 280 words answering four specified questions is required, and an Author Contributions section must list only the allowed roles of wrote the manuscript, designed the research, performed the research, analyzed the data, and optionally contributed new reagents/analytical tools.
References
References must be listed in citation order, include article titles, list up to six authors or the first three followed by et al. if more than six, and include only published works or manuscripts in press.
Figures & Tables
Figures must be uploaded separately as individual files, while tables are included in the main text file. Figure legends must appear after the References, and composite figures must be submitted preassembled.
Review
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract is required and must be 250 words. Abstract must be 250 words. Abstract must be unstructured. Abstract must not include headers.
Manuscript
Manuscript must not exceed 8,000 words, excluding the title page, abstract or introduction, references, acknowledgements, tables, and figures. Manuscript must include a title page, a 75-word introduction with no references, text with appropriate headings chosen by the authors, acknowledgements, references, figure legends, and tables. Main text must include keywords, and if artificial intelligence is used it must be credited in the acknowledgements or methods section.
References
References must be listed in citation order, include article titles, include up to six authors or the first three followed by et al. if more than six, and include only published works or manuscripts in press.
Figures & Tables
Figures must be uploaded separately as individual files, while tables are included in the main text file. Figures and tables must not duplicate information in the text, and each table must include a title while each figure legend must include a brief title and enough information to understand the figure without referring to the text.
Systematic Review
Cover Letter
Cover Letter requirements are not specified.
Abstract
An abstract is required. The abstract must be 250 words. The abstract must be unstructured.
Manuscript
The manuscript must not exceed 8,000 words. The manuscript must include a title page, abstract, Introduction, Methods, Results, Discussion, Acknowledgements, Author Contributions, References, Figure Legends, Tables, and a Study Highlights section placed after the Discussion. The manuscript must include keywords and a Study Highlights section under 280 words that answers four questions on current knowledge, the study question, what the study adds, and how it may change clinical pharmacology or translational science, and it must include an Author Contributions section limited to the roles wrote the manuscript, designed the research, performed the research, analyzed the data, and where applicable contributed new reagents/analytical tools, with any AI use credited in the acknowledgements or methods section.
References
References must be listed in the order cited, include only published works or manuscripts in press, list all authors up to six and otherwise the first three followed by et al., and include article titles.
Figures & Tables
Figures must be uploaded separately as individual files, while tables must be included in the main text file. Figure legends must appear after the Reference section, and figures and tables must not duplicate information in the text.
Meta-Analysis
Cover Letter
Cover Letter requirements are not specified.
Abstract
An abstract is required for Meta-Analysis submissions. The abstract must be 250 words. The abstract must be unstructured. Abstract headers must not be included.
Manuscript
The manuscript is limited to 8,000 words, excluding the title page, abstract or introduction, references, acknowledgements, tables, and figures. The manuscript must include a title page, Study Highlights, Introduction, Methods, Results, Discussion, Acknowledgements, Author Contributions, References, Figure Legends, and Tables. A Study Highlights section under 280 words answering four specified questions and an Author Contributions section limited to the roles wrote the manuscript, designed the research, performed the research, analyzed the data, and where applicable contributed new reagents/analytical tools must be included.
References
References must be listed in citation order, include article titles, list up to six authors or the first three followed by et al. if more than six, and include only published works or manuscripts in press.
Figures & Tables
Figures must be uploaded separately as individual files, while tables are included in the main text file. Figures and tables must not duplicate information in the text, and figures must be numbered consecutively in the order first cited.
Brief Report
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract is required for Brief Reports. Abstract must be 250 words. Abstract must be unstructured.
Manuscript
Brief Reports have a 2,000-word limit. Manuscript must include a title page, Introduction, Methods, Results, Discussion, Acknowledgements, Author Contributions, References, Figure Legends, and Tables. Manuscript must include a Study Highlights section under 280 words answering four questions and an Author Contributions section limited to the roles wrote the manuscript, designed the research, performed the research, analyzed the data, and, where applicable, contributed new reagents/analytical tools.
References
References must be listed in citation order, include only published works or manuscripts in press, give all authors up to six or the first three followed by et al. if more than six, and include article titles.
Figures & Tables
Figures must be uploaded separately as individual files, while tables are included in the main text file. Figure legends must appear after the references, and figures and tables must not duplicate information in the text.
Mini-Review
Cover Letter
Cover Letter requirements are not specified.
Abstract
An abstract is required. Abstract must be 250 words. Abstract must be unstructured. Abstract must not include headers.
Manuscript
Mini-Reviews must be 2,000–3,000 words, excluding the title page, abstract or introduction, references, acknowledgements, tables, and figures. The main text file must include a title page, an unstructured abstract, keywords, body text, references, tables, and figure legends. Keywords must be included, and any AI use must be credited in the acknowledgements or methods section.
References
References must be listed in citation order, include article titles, list up to six authors or the first three followed by et al. when there are more than six, and include only published works or manuscripts in press.
Figures & Tables
Figures must be uploaded separately as individual files, while tables are included in the main text file. Figures and tables must not duplicate information in the text, tables created solely of references are not permitted, and composite figures must be submitted preassembled.
Letter To The Editor
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract must be unstructured. Abstract must not include headers.
Manuscript
Main text file must include a title page, an unstructured abstract, keywords, body text, references, tables, and figure legends.
References
References must be listed in the order cited, include article titles, list up to six authors or the first three followed by et al. if more than six, and use italicized abbreviated journal names without periods.
Figures & Tables
Figures must be uploaded separately as individual files, while tables must be included in the main text file. Figures and tables must not duplicate information in the text.
Mechanism Of Action Mini Reviews
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract must be unstructured and must not include headers.
Manuscript
Manuscript must include Introduction, Drug Regulatory Approval, Mechanism of Action, Pharmacokinetic/Pharmacodynamic characteristics, Key Clinical Trials, and Clinical Efficacy and Safety sections, and it may also include a Future Prospects section. Manuscript must include a key figure for the drug pathway or mechanistic action and an information box titled "Clinical & Translational Card for [Drug generic name]" containing mechanism of action and indication(s), dosage and administration, the major metabolic pathway if feasible, and key PK characteristics including AUC, Cmax, tmax, and t1/2.
References
References must be listed in the order cited, include article titles, list up to six authors or the first three followed by et al. if more than six, and include only published works or manuscripts in press.
Figures & Tables
A key figure for the drug pathway or mechanistic action is required. Figures must be uploaded separately as individual files, while tables are included in the main text file.
Response Letter To The Editor
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract must be unstructured. Abstract must not include headers.
Manuscript
Title must use the format "Response to [title of Letter]," and the manuscript must reference the Letter to the Editor in the first few paragraphs. Main text file must include a title page, an unstructured abstract, keywords, body text, references, tables, and figure legends.
References
References must be listed in citation order, include article titles, list up to six authors or the first three followed by et al. if more than six, and include only published works or manuscripts in press.
Figures & Tables
Figures must be uploaded separately as individual files, while tables must be included in the main text file. Figure legends must appear after the References section, and each table and figure must have a descriptive title or legend that allows it to be understood.
Recent Publications
Correction to “Severe Thiopurine‐Induced Myelosuppression in a Pediatric Acute Lymphoblastic Leukemia Patient ith the NUDT15 *1/*6 Genotype: A Brief Report”
-
10.1111/cts.70652
View Publication
Model‐Informed Development of a Subcutaneous Formulation of Tislelizumab: Phase 1 Pharmacokinetics in Patients With Cancer
Xiangyu Liu, Ye Guan, Yixi Liu, Tian Yu, Ramil Abdrashitov, Ziru Niu, Xiao Lin, Xiaohan Ye, Yutong Wang, Srikumar Sahasranaman, William D. Hanley, Nageshwar Budha
10.1111/cts.70649
View Publication
A Phase 1, Open‐Label, Randomized Study to Investigate the Pharmacokinetics and Safety of Multiple Doses of Intranasal Naloxone in Healthy Participants
David Cassie, Bob Warnock, Faisal Akhtar, Duncan McCloskey, David Wyatt
10.1111/cts.70640
View Publication
EPHX2 Orchestrates Intestinal Epithelial Barrier Repair in Ulcerative Colitis: An Integrated Multi‐Omics and Experimental Study
Tian Dai, Siyu Han, Xiaoping Hu, Jiakuo Gu, Dongmei Liu, Jiale Wu, Juyan Zheng, Shiqin Hong, Yiwen Zhang
10.1111/cts.70651
View Publication
Frequently asked questions
How long does it take to publish?
Median submission to first decision is 32 days, median submission to acceptance is 99 days, and median acceptance to publication is 24 days.
Reformat to Clinical and Translational Science using Livewrite PremiumIs a cover letter required?
A cover letter is part of the accepted file formats and may be used to explain omission of proprietary structural information or absence of IRB review.
Reformat to Clinical and Translational Science using Livewrite PremiumWhat are the publication costs?
Article publication charge: $3,990 USD / £3,030 GBP / €3,400 EUR if accepted and published. American Society for Clinical Pharmacology and Therapeutics members receive 19% off the full APC. APCs are waived for Book Review, Commentary, and Perspective.
Reformat to Clinical and Translational Science using Livewrite PremiumResearch Topics
Health and Medical Research Impacts
Pharmacogenetics and Drug Metabolism
Health Systems, Economic Evaluations, Quality of Life
Statistical Methods in Clinical Trials
Pharmaceutical studies and practices
Ethics in Clinical Research
Drug Transport and Resistance Mechanisms
Biomedical Ethics and Regulation
Health Policy Implementation Science
Health Sciences Research and Education
Biosimilars and Bioanalytical Methods
Biomedical and Engineering Education
Pharmaceutical Economics and Policy
Pharmacological Effects and Toxicity Studies
Computational Drug Discovery Methods
Cardiac electrophysiology and arrhythmias
Monoclonal and Polyclonal Antibodies Research
Diverse Scientific and Economic Studies
COVID-19 Clinical Research Studies
Chronic Lymphocytic Leukemia Research
Antibiotics Pharmacokinetics and Efficacy
Cancer Genomics and Diagnostics
SARS-CoV-2 and COVID-19 Research
Meta-analysis and systematic reviews
CAR-T cell therapy research