Ep

Epigenetics

Epigenetics publishes international research on heritable changes in gene expression caused by mechanisms other than modification of the DNA sequence. The journal covers epigenetic mechanisms such as nucleosome positioning, DNA methylation, histone modifications, non-coding RNAs, imprinting, chromatin remodelling complexes, and epitranscriptomics, as well as the role of epigenetics in health, disease, aging, development, therapy, and diagnostics. It uses single anonymized peer review and has operated as a fully open access journal since Volume 18 (2023).

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Impact Factor 3.2
Quartile Q2
Open Access Type Open
ISSN 1559-2294
eISSN 1559-2308
Invitation Only No
Cost Range Standard APC: $3940 / £2920 / EUR 3505 / AUD 5485; Epigenetics Society members receive a 15% discount; discretionary waivers may be considered.

Submission Instructions

Epigenetics accepts the following article types. Click on an article type to view submission instructions.

Research Papers

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be non-structured.
Manuscript Manuscript should be organized as title page, abstract, keywords, main text with introduction, materials and methods, results, and discussion, followed by acknowledgments, declaration of interest statement, references, appendices as appropriate, tables with captions, figures, and a list of figure captions. Manuscript must include a word count, no more than 6 keywords, a disclosure statement under the subheading “Disclosure of interest,” and a short biographical note of no more than 200 words for each author.
References References may be in any style or format if a consistent scholarly citation format is used. References must include author name(s), journal or book title, article or chapter title, year of publication, volume and issue where appropriate, page numbers, and a corresponding in-text citation for every bibliographic entry.
Figures & Tables Figures and tables may be placed within the text or submitted as separate documents. Tables must be supplied as editable files and should be understandable without reference to the text.
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Review

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be non-structured.
Manuscript A word count must be included for the paper, but no manuscript word, page, or character limit is stated. Manuscript should be compiled in the order title page, abstract, keywords, main text with introduction, materials and methods, results, and discussion, acknowledgments, declaration of interest statement, references, appendices as appropriate, tables with captions, figures, and figure captions. Manuscript must include no more than 6 keywords, a disclosure statement under the subheading “Disclosure of interest,” and a short biographical note of no more than 200 words for each author.
References References may be in any style or format if a consistent scholarly citation format is used. References must include author name(s), journal or book title, article or chapter title, year of publication, volume and issue where appropriate, page numbers, and a corresponding in-text citation for every bibliographic entry.
Figures & Tables Figures and tables may be placed within the text or submitted as separate documents. Tables must be supplied as editable files.
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Research Article

Cover Letter Cover Letter requirements are not specified.
Abstract A non-structured abstract is required. Abstract must not exceed 350 words. Abstract must be non-structured.
Manuscript A word count for the paper must be included. Manuscript should be organized as title page, abstract, keywords, introduction, materials and methods, results, discussion, acknowledgments, declaration of interest statement, references, appendices as appropriate, tables with captions, figures, and figure captions. Manuscript must include no more than 6 keywords, a disclosure of interest statement, a short biographical note for each author of no more than 200 words, and for original research a written ethics approval and consent statement in the Methods section where applicable.
References References may be in any consistent scholarly citation style or format. References must include full bibliographic details, every reference list entry must have a corresponding in-text citation, and datasets cited in the article must also appear in the reference list.
Figures & Tables Figures and tables may be embedded within the manuscript text or submitted as separate documents. Tables must be supplied as editable files and figures must be sufficient for peer review.
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Brief Communications

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be non-structured.
Manuscript A word count must be included for the paper. Manuscript should be organized in the order title page, abstract, keywords, main text with introduction, materials and methods, results, and discussion, acknowledgments, disclosure of interest statement, references, appendices if applicable, tables with captions, figures, and figure captions. Manuscript must include no more than 6 keywords, a disclosure of interest statement under the subheading “Disclosure of interest,” and a short biographical note of no more than 200 words for each author.
References References may be in any consistent scholarly citation style or format. References must include author name, source title, article or chapter title, year, volume and issue where appropriate, page numbers, and a corresponding in-text citation for every entry.
Figures & Tables Figures and tables may be placed within the text or submitted as separate documents. Tables must be supplied as editable files.
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Letter To The Editor

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 350 words. Abstract must be non-structured.
Manuscript Manuscript should be compiled in the order of title page, abstract, keywords, main text, acknowledgments, disclosure of interest statement, references, appendices as appropriate, tables with captions, figures, and figure captions. Manuscript must include a word count, no more than 6 keywords, and a disclosure statement under the subheading “Disclosure of interest.”
References References may be in any consistent scholarly citation style or format. References must include author name(s), journal or book title, article or chapter title, year of publication, volume and issue where appropriate, page numbers, and a corresponding in-text citation for every entry.
Figures & Tables Figures and tables may be placed within the text or submitted as separate documents. Tables must be understandable without reference to the text and supplied as editable files.
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Rapid Communication

Cover Letter Cover Letter requirements are not specified.
Abstract A non-structured abstract is required. Abstract must not exceed 350 words. Abstract must be non-structured.
Manuscript Manuscript should be compiled in the order of title page, abstract, keywords, main text with introduction, materials and methods, results, and discussion, acknowledgments, disclosure of interest statement, references, appendices as appropriate, tables with captions, figures, and figure captions. Manuscript must include a word count, no more than 6 keywords, and a disclosure of interest statement under the subheading “Disclosure of interest.”
References References may be in any consistent scholarly citation format. References must include author name(s), source title, article or chapter title, year, volume and issue where appropriate, page numbers, and a corresponding in-text citation for every bibliographic entry.
Figures & Tables Figures and tables may be placed within the text or submitted as separate documents. Tables must be supplied as editable files.
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Brief Report

Cover Letter Cover Letter requirements are not specified.
Abstract A non-structured abstract is required. Abstract must not exceed 350 words. Abstract must be non-structured.
Manuscript Manuscript should be organized in the order of title page, abstract, keywords, main text with introduction, materials and methods, results, discussion, acknowledgments, declaration of interest statement, references, appendices as appropriate, tables with captions, figures, and figure captions. Manuscript must include a word count, no more than 6 keywords, a disclosure of interest statement, and for original research involving humans, animals, plants, biological material, protected or non-public datasets, collections, or sites, a written ethics statement in the Methods section confirming approval and consent where relevant.
References References may be in any consistent scholarly citation style or format. References must include author name(s), journal or book title, article or chapter title, year of publication, volume and issue where appropriate, page numbers, and a corresponding in-text citation for every bibliographic entry.
Figures & Tables Figures and tables may be placed within the text or submitted as separate documents. Tables must be supplied as editable files.
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Recent Publications

N6-methyladenosine modification of mRNAs in retinal ischemia-reperfusion in mice

Jingying Liang, Yuke Li, Yuwen Wen, Zhidong Li, Caibin Deng, Yehong Zhuo, Yangyang Li, Yingting Zhu

10.1080/15592294.2026.2700836
View Publication

Epigenetic regulation of vertebrate limb development: from field specification to tissue morphogenesis

Claudia Monserrat Vallejo-De Lira, Claudio Iván Galván-Hernández, Jesús Chimal-Monroy, Jessica Cristina Marin-Llera

10.1080/15592294.2026.2695477
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Dnmt1 associated Gja1 promoter methylation changes are implicated in Cx43 remodeling during acute myocardial ischemia/reperfusion injury

Yang Liu, Zijun Wang, Youxiao Zhao, Yanyan Ma, Jing Yi, Yingnan Song, Yanqiu Liu, Li An, Zhijun Pan, Hong Gao, Ying Cao

10.1080/15592294.2026.2694817
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Differential CpG methylation in the Interferon Gamma ( IFNG ) promoter correlates with viral load and transcriptional control in people with HIV

Megha S. Srivatsa, Momtahina Tahmida, Tara Tenenbaum, Susan J. Little, Brian LaMere, Sara Gianella, Sarah A. LaMere

10.1080/15592294.2026.2693337
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m6A methylation of circKPNA2 promotes colorectal carcinogenesis by activating the RIN1-Ras pathway

Jinhai Tian, Zongying Jiang, Qi Huang, Jia Wang, Yaqin He

10.1080/15592294.2026.2672219
View Publication

Frequently asked questions

How long does it take to publish?

4 days average from submission to first decision; 49 days average from submission to first post-review decision; 12 days average from acceptance to online publication.

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Is a cover letter required?

If third-party content is used under fair dealing or fair use without obtaining permission, authors should inform the editorial team in the cover letter or query the editor prior to submission.

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What are the publication costs?

Standard APC: $3940 / £2920 / EUR 3505 / AUD 5485; Epigenetics Society members receive a 15% discount; discretionary waivers may be considered.

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Research Topics

Epigenetics and DNA Methylation RNA modifications and cancer Cancer-related gene regulation Genomics and Chromatin Dynamics Genetic Syndromes and Imprinting Birth, Development, and Health Cancer-related molecular mechanisms research Genetics and Neurodevelopmental Disorders Histone Deacetylase Inhibitors Research MicroRNA in disease regulation Prenatal Screening and Diagnostics RNA Research and Splicing Chromosomal and Genetic Variations Neonatal Respiratory Health Research Pregnancy and preeclampsia studies Plant Molecular Biology Research CRISPR and Genetic Engineering Cancer Genomics and Diagnostics Protein Degradation and Inhibitors Health, Environment, Cognitive Aging Genetic Associations and Epidemiology Circular RNAs in diseases Pluripotent Stem Cells Research Folate and B Vitamins Research Ubiquitin and proteasome pathways