Overview Submission Instructions Recent Publications Frequently Asked Questions Research Topics

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Epigenetics

Epigenetics publishes international research on heritable changes in gene expression caused by mechanisms other than modification of the DNA sequence. The journal covers epigenetic mechanisms such as nucleosome positioning, DNA methylation, histone modifications, non-coding RNAs, imprinting, chromatin remodelling complexes, and epitranscriptomics, as well as the role of epigenetics in health, disease, aging, development, therapy, and diagnostics. It uses single anonymized peer review and has operated as a fully open access journal since Volume 18 (2023).

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Subject Genetics & Heredity

Impact Factor 3.2

Quartile Q2

Open Access Type Open

ISSN 1559-2294

eISSN 1559-2308

Invitation Only No

Cost Range Standard APC: $3940 / £2920 / EUR 3505 / AUD 5485; Epigenetics Society members receive a 15% discount; discretionary waivers may be considered.

Submission Instructions

Epigenetics accepts the following article types. Click on an article type to view submission instructions.

Research Papers

Cover Letter Cover Letter requirements are not specified.

Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be non-structured.

Manuscript Manuscript should be organized as title page, abstract, keywords, main text with introduction, materials and methods, results, and discussion, followed by acknowledgments, declaration of interest statement, references, appendices as appropriate, tables with captions, figures, and a list of figure captions. Manuscript must include a word count, no more than 6 keywords, a disclosure statement under the subheading “Disclosure of interest,” and a short biographical note of no more than 200 words for each author.

References References may be in any style or format if a consistent scholarly citation format is used. References must include author name(s), journal or book title, article or chapter title, year of publication, volume and issue where appropriate, page numbers, and a corresponding in-text citation for every bibliographic entry.

Figures & Tables Figures and tables may be placed within the text or submitted as separate documents. Tables must be supplied as editable files and should be understandable without reference to the text.

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Review

Cover Letter Cover Letter requirements are not specified.

Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be non-structured.

Manuscript A word count must be included for the paper, but no manuscript word, page, or character limit is stated. Manuscript should be compiled in the order title page, abstract, keywords, main text with introduction, materials and methods, results, and discussion, acknowledgments, declaration of interest statement, references, appendices as appropriate, tables with captions, figures, and figure captions. Manuscript must include no more than 6 keywords, a disclosure statement under the subheading “Disclosure of interest,” and a short biographical note of no more than 200 words for each author.

Figures & Tables Figures and tables may be placed within the text or submitted as separate documents. Tables must be supplied as editable files.

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Research Article

Cover Letter Cover Letter requirements are not specified.

Abstract A non-structured abstract is required. Abstract must not exceed 350 words. Abstract must be non-structured.

Manuscript A word count for the paper must be included. Manuscript should be organized as title page, abstract, keywords, introduction, materials and methods, results, discussion, acknowledgments, declaration of interest statement, references, appendices as appropriate, tables with captions, figures, and figure captions. Manuscript must include no more than 6 keywords, a disclosure of interest statement, a short biographical note for each author of no more than 200 words, and for original research a written ethics approval and consent statement in the Methods section where applicable.

References References may be in any consistent scholarly citation style or format. References must include full bibliographic details, every reference list entry must have a corresponding in-text citation, and datasets cited in the article must also appear in the reference list.

Figures & Tables Figures and tables may be embedded within the manuscript text or submitted as separate documents. Tables must be supplied as editable files and figures must be sufficient for peer review.

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Brief Communications

Cover Letter Cover Letter requirements are not specified.

Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be non-structured.

Manuscript A word count must be included for the paper. Manuscript should be organized in the order title page, abstract, keywords, main text with introduction, materials and methods, results, and discussion, acknowledgments, disclosure of interest statement, references, appendices if applicable, tables with captions, figures, and figure captions. Manuscript must include no more than 6 keywords, a disclosure of interest statement under the subheading “Disclosure of interest,” and a short biographical note of no more than 200 words for each author.

References References may be in any consistent scholarly citation style or format. References must include author name, source title, article or chapter title, year, volume and issue where appropriate, page numbers, and a corresponding in-text citation for every entry.

Figures & Tables Figures and tables may be placed within the text or submitted as separate documents. Tables must be supplied as editable files.

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Letter To The Editor

Cover Letter Cover Letter requirements are not specified.

Abstract Abstract must not exceed 350 words. Abstract must be non-structured.

Manuscript Manuscript should be compiled in the order of title page, abstract, keywords, main text, acknowledgments, disclosure of interest statement, references, appendices as appropriate, tables with captions, figures, and figure captions. Manuscript must include a word count, no more than 6 keywords, and a disclosure statement under the subheading “Disclosure of interest.”

References References may be in any consistent scholarly citation style or format. References must include author name(s), journal or book title, article or chapter title, year of publication, volume and issue where appropriate, page numbers, and a corresponding in-text citation for every entry.

Figures & Tables Figures and tables may be placed within the text or submitted as separate documents. Tables must be understandable without reference to the text and supplied as editable files.

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Rapid Communication

Cover Letter Cover Letter requirements are not specified.

Abstract A non-structured abstract is required. Abstract must not exceed 350 words. Abstract must be non-structured.

Manuscript Manuscript should be compiled in the order of title page, abstract, keywords, main text with introduction, materials and methods, results, and discussion, acknowledgments, disclosure of interest statement, references, appendices as appropriate, tables with captions, figures, and figure captions. Manuscript must include a word count, no more than 6 keywords, and a disclosure of interest statement under the subheading “Disclosure of interest.”

References References may be in any consistent scholarly citation format. References must include author name(s), source title, article or chapter title, year, volume and issue where appropriate, page numbers, and a corresponding in-text citation for every bibliographic entry.

Figures & Tables Figures and tables may be placed within the text or submitted as separate documents. Tables must be supplied as editable files.

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Brief Report

Cover Letter Cover Letter requirements are not specified.

Abstract A non-structured abstract is required. Abstract must not exceed 350 words. Abstract must be non-structured.

Manuscript Manuscript should be organized in the order of title page, abstract, keywords, main text with introduction, materials and methods, results, discussion, acknowledgments, declaration of interest statement, references, appendices as appropriate, tables with captions, figures, and figure captions. Manuscript must include a word count, no more than 6 keywords, a disclosure of interest statement, and for original research involving humans, animals, plants, biological material, protected or non-public datasets, collections, or sites, a written ethics statement in the Methods section confirming approval and consent where relevant.

Figures & Tables Figures and tables may be placed within the text or submitted as separate documents. Tables must be supplied as editable files.

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Recent Publications

Multi-omics analysis reveals new pathogenic methylation sites, genes, and potential regulatory pathways in essential hypertension

Xinmeng Hu, Huizhen Jin, Xiaoyang Li, Zhuoshuai Liang, Jikang Shi, Hongrui Zhang, Jiahui Zhao, Yong Li, Yunkai Liu, Yi Cheng, Yawen Liu

10.1080/15592294.2026.2653955

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M6A-dependent regulation of microRNAs from CKD stage 5 patients: insights from epigenetic modification analysis

Zhiqian Yang, Fanna Liu, Mingjun Ye, Qiang Yan, Zhipeng Zeng, Jingsheng Ma, Haitao Li, Hualin Ma, Xinzhou Zhang, Xiaofeng Zhu, Yong Dai, Donge Tang

10.1080/15592294.2026.2653962

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The role of R-loops-mediated epigenetic regulation in genome stability maintenance and disease pathogenesis: a systematic review

Zi Hao Jiang, Di Feng Wang, Rui Shao, Xing Sheng Wang, Zi Ren Tang

10.1080/15592294.2026.2653959

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Direct and indirect genetic effects of birthweight predisposition on child DNA methylation at birth

Nicole Creasey, Leonard Frach, Elena Isaevska, Janine F. Felix, Charlotte Cecil, Jean-Baptiste Pingault, Alexander Neumann

10.1080/15592294.2026.2654101

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Differential DNA methylation clock ages across buffy coat (BC), peripheral blood mononuclear cells (PBMC), and saliva in individuals in early-to-mid adulthood

Ryan Bruellman, Donald Evans, Andrew Smolen, Luke M. Evans, Chandra A. Reynolds

10.1080/15592294.2026.2653960

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Frequently asked questions

How long does it take to publish?

4 days average from submission to first decision; 49 days average from submission to first post-review decision; 12 days average from acceptance to online publication.

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Is a cover letter required?

If third-party content is used under fair dealing or fair use without obtaining permission, authors should inform the editorial team in the cover letter or query the editor prior to submission.

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What are the publication costs?

Standard APC: $3940 / £2920 / EUR 3505 / AUD 5485; Epigenetics Society members receive a 15% discount; discretionary waivers may be considered.

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Research Topics

Epigenetics and DNA Methylation RNA modifications and cancer Cancer-related gene regulation Genomics and Chromatin Dynamics Genetic Syndromes and Imprinting Birth, Development, and Health Cancer-related molecular mechanisms research Genetics and Neurodevelopmental Disorders Histone Deacetylase Inhibitors Research MicroRNA in disease regulation Prenatal Screening and Diagnostics RNA Research and Splicing Chromosomal and Genetic Variations Neonatal Respiratory Health Research Pregnancy and preeclampsia studies Plant Molecular Biology Research CRISPR and Genetic Engineering Cancer Genomics and Diagnostics Protein Degradation and Inhibitors Health, Environment, Cognitive Aging Genetic Associations and Epidemiology Circular RNAs in diseases Pluripotent Stem Cells Research Folate and B Vitamins Research Ubiquitin and proteasome pathways

Related Journals

Heredity Springer Nature

Epigenomes Multidisciplinary Digital Publishing Institute

Molecular Therapy Elsevier BV

The American Journal of Human Genetics Elsevier BV

Genetics in Medicine Elsevier BV

Mitochondrion Elsevier BV