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Clinical Epigenetics

Clinical Epigenetics is an open access journal covering the broad spectrum of epigenetics research from basic research to innovations in therapeutic treatments, with a focus on epigenetic principles and mechanisms as applied to human development, disease, diagnosis and treatment. The journal welcomes submissions involving clinical trials, translational research, new and innovative methodologies, and mechanistic insights provided by model organisms.

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Subject Genetics & Heredity, Oncology
Impact Factor 4.4
Quartile Q1
Open Access Type Open
ISSN 1868-7075
eISSN 1868-7083
Invitation Only No
Cost Range APC: £2790.00 GBP / $3890.00 USD / €3190.00 EUR, plus VAT or local taxes where applicable.

Submission Instructions

Clinical Epigenetics accepts the following article types. Click on an article type to view submission instructions.

Research

Cover Letter A cover letter is required and should include why the manuscript should be published, any issues relating to journal policies, potential competing interests, confirmation that all authors approved submission, confirmation that the work has not been published or submitted elsewhere, reviewer suggestions, and the special issue name if applicable. Cover letter should explain the manuscript’s suitability for publication, note any journal policy issues, declare potential competing interests, confirm all authors approved submission, confirm the work has not been published or submitted elsewhere, include reviewer suggestions, and name any relevant special issue.
Abstract An abstract is required. Abstract must not exceed 350 words. Abstract should be structured. Abstract must include the headings Background, Results, and Conclusions.
Manuscript Manuscript should include a Background section, a methods section covering aim, design, setting, participants or materials, processes, interventions and comparisons, a Results section, a Discussion section, a Conclusions section, and a Declarations section. Manuscript must include three to ten keywords and a Declarations section with the subheadings Ethics approval and consent to participate, Consent for publication, Availability of data and materials, Competing interests, Funding, Authors' contributions, Acknowledgements, and Authors' information, with any irrelevant subheading retained and marked 'Not applicable'.
References References must follow Vancouver style. Only published, in-press, clinical trial registration records, abstracts, or publicly available preprints may be cited, unpublished abstracts, unpublished data, and personal communications must be excluded from the reference list, journal abbreviations must follow Index Medicus/MEDLINE, and URLs must appear as numbered references in full.
Figures & Tables Tables shorter than one page may be placed within the manuscript, larger tables may be placed at the end of the document, and figures must be uploaded separately in the order first cited. Multi-panel figures must be submitted as a single composite file, figure titles and legends must be provided in the manuscript rather than the image file, and tables must be created using the word processor’s table function rather than embedded as figures.
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Review

Cover Letter A cover letter is required, and unsolicited review submissions should include the author's track record and expertise, five articles by the authors directly related to the topic, reasons for relevance to the journal, reviewer suggestions, an explanation of why the manuscript should be published, any issues relating to journal policies, competing interests, confirmation of all authors' approval, and, if applicable, the special issue name. The cover letter must explain why the manuscript should be published, address any issues relating to journal policies, declare potential competing interests, confirm all authors approved submission, and for unsolicited reviews also include the author's track record and expertise, five directly related articles by the authors, reasons for relevance to the journal, and peer reviewer suggestions.
Abstract An abstract is required. The abstract must not exceed 350 words. The abstract must be structured. The abstract must include Background, a main body of the abstract, and a short conclusion.
Manuscript The manuscript should include Background and Conclusions sections, may use short informative subsection headings in the main text, and must include a Declarations section. The manuscript must include three to ten keywords, a list of abbreviations if abbreviations are used, and a Declarations section with the subheadings Ethics approval and consent to participate, Consent for publication, Availability of data and materials, Competing interests, Funding, Authors' contributions, Acknowledgements, and optional Authors' information, with 'Not applicable' used for any irrelevant declaration.
References References must follow Vancouver style. Only published, in-press, or publicly available preprint articles, clinical trial registration records, and abstracts may be cited; unpublished abstracts, unpublished data, and personal communications must not appear in the reference list; journal abbreviations must follow Index Medicus/MEDLINE; and web links and URLs must be numbered and included in the reference list in full.
Figures & Tables Tables shorter than one page may be placed within the manuscript, longer tables may be placed at the end of the text file, and figure titles and legends must appear in the main manuscript while figures are uploaded separately in cited order. Multi-panel figures must be submitted as a single composite file, figure titles must not exceed 15 words, figure legends and table legends must not exceed 300 words, table titles must not exceed 15 words, tables must not be embedded as figures or spreadsheet files, and tables must be created using the word processor's table function.
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Brief Report

Cover Letter A cover letter is required and should include suggested peer reviewers. The cover letter must explain why the manuscript should be published, explain any issues relating to journal policies, declare any potential competing interests, confirm all authors approved submission, confirm the content is not published or submitted elsewhere, and name the special issue if applicable.
Abstract An abstract is required. The abstract must not exceed 100 words. The abstract should be unstructured. The abstract should briefly summarize the aim, findings, or purpose of the article and should minimize abbreviations and contain no references.
Manuscript The manuscript must be no longer than 2,000 words excluding the abstract and references. The manuscript must contain Introduction, Methods, Results and Discussion sections with no further subheadings. The manuscript must include three to ten keywords, a Declarations section with the specified subheadings, and an Availability of data and materials statement.
References The manuscript may include a maximum of 10 references. References must follow Vancouver style. Only published articles, clinical trial registration records, and published or publicly available abstracts may be cited, unpublished abstracts, unpublished data, and personal communications must be excluded from the reference list, journal abbreviations must follow Index Medicus/MEDLINE, and URLs must be numbered and included in the reference list.
Figures & Tables The manuscript may include no more than 2 figures or tables. Tables shorter than one page may be placed within the manuscript, longer tables may be placed at the end of the text file, and figures must be uploaded separately in the order first cited. Figure titles and table titles must not exceed 15 words, figure legends and table legends must not exceed 300 words, and tables must not be embedded as figures or spreadsheet files.
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Correspondence

Cover Letter A cover letter is required. Cover letter must explain why the manuscript should be published, address any issues relating to journal policies, declare any potential competing interests, confirm all authors approved submission, confirm the content has not been published or submitted elsewhere, and name the special issue if applicable.
Abstract Abstract must not be included.
Manuscript Manuscript must be no longer than 1,000 words excluding references. Correspondence may be broken into subsections with short, informative headings and must include a 'Declarations' section with the subheadings 'Ethics approval and consent to participate', 'Consent for publication', 'Availability of data and materials', 'Competing interests', 'Funding', 'Authors' contributions', and 'Acknowledgements', with 'Authors' information' optional. Manuscript must include three to ten keywords, must write 'Not applicable' under any irrelevant Declarations subheading, and must not include supplementary information.
References References must not exceed 10. References must follow Vancouver style. Only published articles, clinical trial registration records, and abstracts or items available on public preprint servers may be cited, unpublished abstracts, unpublished data, and personal communications must not appear in the reference list, journal abbreviations must follow Index Medicus/MEDLINE, and URLs must be assigned a reference number and listed in full in the references.
Figures & Tables A maximum of one small figure or table may be included. Tables shorter than one page may be placed within the manuscript, tables longer than one page may be placed at the end of the text file, and figures are uploaded separately. Figures and tables must be numbered in the order cited in the text, figure titles and table titles must not exceed 15 words, figure legends and table legends must not exceed 300 words, and tables must not be embedded as figures.
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Recent Publications

BDNF exon IV promoter methylation and antidepressant action: a complex interplay

Hansi Pathak, Anton Borchert, Sara Garaali, Alexandra Burkert, Helge Frieling

10.1186/s13148-022-01415-3
View Publication

Genome-wide distribution of histone trimethylation reveals a global impact of bisphenol A on telomeric binding proteins and histone acetyltransferase factors: a pilot study with human and in vitro data

Shereen Cynthia D’Cruz, Chunxiang Hao, Martin Labussiere, Vicente Mustieles, Carmen Freire, Louis Legoff, Laura Magnaghi-Jaulin, Alicia Olivas-Martinez, Andrea Rodriguez-Carrillo, Christian Jaulin, Arthur David, Mariana F. Fernandez, Fatima Smagulova

10.1186/s13148-022-01408-2
View Publication

Altered DNA methylation in estrogen-responsive repetitive sequences of spermatozoa of infertile men with shortened anogenital distance

Ludwig Stenz, Matthias Beyens, Mark E. Gill, Ariane Paoloni-Giacobino, Christian De Geyter

10.1186/s13148-022-01409-1
View Publication

Circulating cell-free DNA methylation mirrors alterations in cerebral patterns in epilepsy

Ricardo Martins-Ferreira, Bárbara Leal, João Chaves, Laura Ciudad, Raquel Samões, António Martins da Silva, Paulo Pinho Costa, Esteban Ballestar

10.1186/s13148-022-01416-2
View Publication

Maintenance of methylation profile in imprinting control regions in human induced pluripotent stem cells

A. Pham, C. Selenou, E. Giabicani, V. Fontaine, S. Marteau, F. Brioude, L. David, D. Mitanchez, M. L. Sobrier, I. Netchine

10.1186/s13148-022-01410-8
View Publication

Frequently asked questions

How long does it take to publish?

Submission to first decision (median): 7 days.

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Is a cover letter required?

A cover letter is required. It should explain why the manuscript should be published in Clinical Epigenetics, address any issues relating to journal policies, declare any potential competing interests, confirm that all authors approved the submission, confirm that the content has not been published or submitted elsewhere, and name the special issue if applicable. Authors may also suggest preferred and non-preferred peer reviewers in the cover letter.

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What are the publication costs?

An article processing charge applies for each accepted article. The current APC is £2790.00 GBP / $3890.00 USD / €3190.00 EUR, plus VAT or local taxes where applicable.

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Research Topics

Epigenetics and DNA Methylation RNA modifications and cancer Cancer-related gene regulation Birth, Development, and Health Genetic Syndromes and Imprinting Cancer-related molecular mechanisms research Histone Deacetylase Inhibitors Research Cancer Genomics and Diagnostics MicroRNA in disease regulation Prenatal Screening and Diagnostics Neonatal Respiratory Health Research Genomics and Chromatin Dynamics Genetics and Neurodevelopmental Disorders Acute Myeloid Leukemia Research Genetic Associations and Epidemiology Genetic factors in colorectal cancer Ferroptosis and cancer prognosis Health, Environment, Cognitive Aging Protein Degradation and Inhibitors Pancreatic and Hepatic Oncology Research Pregnancy and preeclampsia studies Childhood Cancer Survivors' Quality of Life Gestational Diabetes Research and Management Immune Cell Function and Interaction Glioma Diagnosis and Treatment

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