MD

Molecular Diagnosis & Therapy

Molecular Diagnosis & Therapy provides researchers and healthcare professionals with insights into the latest molecular diagnostic and therapeutic techniques and their use in precision medicine. The journal publishes reviews and original research articles focused on linking diagnostic and prognostic biomarkers to appropriate therapy, with an emphasis on companion diagnostic and therapeutic products, pharmacogenomic data for drug development, and therapeutic decision making.

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Subject Genetics & Heredity, Pharmacology & Pharmacy
Impact Factor 4.4
Quartile Q1
Open Access Type Hybrid
ISSN 1177-1062
eISSN 1179-2000
Invitation Only No
Cost Range No charge for the traditional subscription-based publishing route; open access publication is available as an option for accepted articles.

Submission Instructions

Molecular Diagnosis & Therapy accepts the following article types. Click on an article type to view submission instructions.

Review Article

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required and must be 150 to 250 words. Abstract must be 150 to 250 words.
Manuscript Review Article manuscripts should be up to 8000 words, excluding the abstract, references, figure legends, and table captions. Manuscript must include a disclosure statement, a statement identifying who had the idea for the article, who performed the literature search and data analysis, and who drafted or critically revised the work, and relevant declarations under the heading "Statements and Declarations," with any use of a Large Language Model documented in the Methods section or another suitable part of the manuscript if no Methods section is available.
References There is no limit on the number of references. References must be cited in the text using numbers in square brackets and listed consecutively in numbered order, including only works cited in the text that have been published or accepted for publication.
Figures & Tables There is no limit on the number of figures or tables. Figures should be submitted within the body of the text unless file size causes upload problems, in which case large figures should be submitted separately from the text. Figures and tables must be numbered with Arabic numerals and cited in the text in consecutive numerical order, with each table and figure accompanied by a caption and figure captions included in the manuscript text file rather than in the figure file.
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Systematic Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required and may be up to 450 words for this article type. Abstract may be up to 450 words.
Manuscript Manuscript should be up to 10000 words, excluding the abstract, references, figure legends, and table captions. Manuscript must include relevant declarations under the heading "Statements and Declarations," and any use of a Large Language Model must be documented in the Methods section or another suitable part of the manuscript if no Methods section is available.
References There is no limit on the number of references. Citations must be numbered in square brackets. Reference list entries must be numbered consecutively and include only works cited in the text that have been published or accepted for publication, with full DOI links provided when available.
Figures & Tables There is no limit on the number of figures or tables. Figures should be submitted within the body of the text unless file size causes upload problems, in which case large figures should be submitted separately. Tables and figures must be numbered with Arabic numerals and cited in consecutive numerical order, with each table and figure accompanied by a caption, and figure captions included in the manuscript text file rather than the figure file.
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Original Research

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required and may be 150 to 250 words, or up to 450 words if needed for full compliance with relevant reporting guidelines. Abstract must be 150 to 250 words, or up to 450 words if needed for full compliance with relevant reporting guidelines.
Manuscript Manuscript should be up to 6000 words, excluding the abstract, references, figure legends, and table captions. Manuscript must include a disclosure statement, relevant declarations under the heading "Statements and Declarations," documentation of any Large Language Model use in the Methods section or another suitable section, and a statement explaining how to access supporting data with links or citations to publicly archived datasets analysed or generated during the study.
References There is no limit on the number of references. Citations must be numbered in square brackets in the text, and the reference list must be numbered consecutively and include only cited works that have been published or accepted for publication.
Figures & Tables There is no limit on the number of figures or tables. Figures should be submitted within the body of the text unless file size causes upload problems, in which case large figures should be submitted separately from the text. Figures and tables must be numbered using Arabic numerals, cited in consecutive numerical order, and each must have a caption.
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Letter To The Editor

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be 150 to 250 words.
Manuscript Letter To The Editor submissions should be up to 1000 words. Manuscript must include relevant declarations under the heading "Statements and Declarations," and any use of a Large Language Model must be documented in the Methods section or another suitable part of the manuscript if no Methods section is available.
References There is no limit on the number of references. References must be cited in the text by numbers in square brackets and listed consecutively in a numbered reference list that includes only cited works published or accepted for publication, with full DOI links when available.
Figures & Tables There is no limit on the number of figures or tables. Figures should be submitted within the body of the text unless file size causes upload problems, in which case large figures should be submitted separately from the text. Tables and figures must be numbered using Arabic numerals and cited in the text in consecutive numerical order, with a caption provided for each.
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Recent Publications

Targeting Cytotoxic T-Cell Effector Function with Granzyme B PET: Translational Advances Toward Predicting Immunotherapy Outcomes

Luca Filippi, Priscilla Guglielmo, Esra Arslan, Elife Akgün, Laura Evangelista

10.1007/s40291-026-00858-1
View Publication

Real-Time Detection of Colorectal Cancer Using Topical Application of a pH-Activatable Fluorophore

Daan G. J. Linders, Jinhui Ser, Md Shamim, Aida Baibussunova, Jasmijn C. J. Loggers, Gilbert Noordam, Davey van den Burg, Gijs J. D. van Acker, Onno R. Guicherit, Marinke Westerterp, Peter J. K. Kuppen, Andreas W. K. S. Marinelli, Denise E. Hilling, Elke E. M. Peters, Satoshi Kashiwagi, Maged Henary, Hak Soo Choi, Alexander L. Vahrmeijer

10.1007/s40291-026-00853-6
View Publication

Correction: Beyond Binary FISH Results: Targeted NGS Provides Deeper Characterization of MYC and Broader Genomic Alterations in DLBCL

Mariana Bastos-Oreiro, Sara Fernández de Córdoba-Oñate, Ismael de la Iglesia-San Sebastián, Francisco Díaz-Crespo, María Chicano Lavilla, Juan Carlos Triviño, Raquel Fernández González, Miguel López-Esteban, Marina Gómez-Llobel, Paula Fernández Caldas, Pablo Silva, Javier Menárguez, Ramón García Sanz, Ismael Buño, Carolina Martínez-Laperche

10.1007/s40291-026-00857-2
View Publication

Extracellular Vesicles in Beta-Thalassemia: Phenotype-Specific Profiles and Potential Clinical Associations

Sirichai Srichairatanakool, Siriporn C. Chattipakorn, Adisak Tantiworawit, Nipon Chattipakorn, Sirinart Kumfu

10.1007/s40291-026-00852-7
View Publication

Heat Shock Proteins as Cancer Biomarkers: From Mechanism to Clinical Application

Prajjwal Kushwaha, Ipsita Roy

10.1007/s40291-026-00851-8
View Publication

Frequently asked questions

How long does it take to publish?

Submission to first decision (median): 7 days.

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Is a cover letter required?

A submission letter is referenced for reviewer suggestions, and the corresponding author should mention any unpublished material included in the manuscript in a cover letter to the Editor.

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What are the publication costs?

No charge for the traditional subscription-based publishing route; optional open access publication is available for accepted articles.

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Research Topics

Cancer Genomics and Diagnostics MicroRNA in disease regulation Lung Cancer Treatments and Mutations Cancer-related molecular mechanisms research Pharmacogenetics and Drug Metabolism CRISPR and Genetic Engineering Circular RNAs in diseases Molecular Biology Techniques and Applications Genetic factors in colorectal cancer Epigenetics and DNA Methylation Colorectal Cancer Treatments and Studies Genomics and Rare Diseases Chronic Lymphocytic Leukemia Research Acute Myeloid Leukemia Research BRCA gene mutations in cancer Prenatal Screening and Diagnostics Cancer Cells and Metastasis Advanced biosensing and bioanalysis techniques Virus-based gene therapy research CAR-T cell therapy research Cancer Immunotherapy and Biomarkers RNA Interference and Gene Delivery Chronic Myeloid Leukemia Treatments RNA modifications and cancer Asthma and respiratory diseases

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