EO

Expert Opinion On Investigational Drugs

Expert Opinion on Investigational Drugs is a MEDLINE-indexed, international subscription-based journal publishing rigorously peer-reviewed review articles and original papers on drugs in preclinical and early-stage clinical development, with emphasis on future treatment strategies and expert opinion on future development. It welcomes Reviews, Drug Evaluations, and Original Research papers, uses double-anonymous peer review, and does not consider case report or case series articles.

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Impact Factor 4.1
Quartile Q1
Open Access Type Closed
ISSN 1354-3784
eISSN 1744-7658
Invitation Only No
Cost Range Individual pricing available on request; institutional online-only subscription USD 13,870.00; institutional print and online subscription USD 20,309.00; local tax added as applicable.

Submission Instructions

Expert Opinion On Investigational Drugs accepts the following article types. Click on an article type to view submission instructions.

Review Articles

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required. Abstract must not exceed 200 words. Abstract must be structured. Abstract must include the headings Introduction, Areas covered, and Expert Opinion/Commentary in that order.
Manuscript Body text must not exceed 7000 words. Manuscript must include an Introduction, a body with numbered subsections, a Conclusion before the Expert Opinion section, and an Expert Opinion section. Manuscript must include an Article Highlights section, 4-10 keywords in alphabetical order, and a statement disclosing whether and how generative AI was used.
References Review Articles should include around 100 references. References must follow NLM style. References must be numbered consecutively in order of first citation and listed at the end in numerical order, with important references marked by one or two asterisks and brief annotations.
Figures & Tables Review Articles may include up to 5 figures and up to 5 tables. Figures and structures must be supplied in separate files from the text. Previously published figures require written permission, and the permission documentation must be uploaded alongside the manuscript.
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Original Research Papers

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required. Abstract must not exceed 200 words. Abstract must be structured. Abstract must include the headings Introduction, Areas covered, and Expert Opinion/Commentary in that order, and it must not contain references.
Manuscript Manuscript must include 5–8 keywords, a financial and competing interests disclosure, and a statement disclosing whether and how generative AI was used or stating that it was not used.
References References must follow NLM style. References must be numbered consecutively in order of first citation and cited in the text with bracketed square-number citations, with the reference list presented in numerical order.
Figures & Tables No more than five figures and five tables are permitted. Figures and structures must be supplied in separate files from the text, and figures must be submitted individually rather than as one file when there are several figures. Tables must be supplied as editable files.
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Drug Evaluations

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required. Abstract must not exceed 200 words. Abstract must be structured. Abstract must include the headings Introduction, Areas covered, and Expert Opinion/Commentary in that order, and it must not contain references.
Manuscript Manuscript must include an Expert Opinion section presenting the author's personal view of the data, likely important future developments, and promising research avenues. Manuscript must include an Article Highlights section and 5–8 keywords, and it must contain a statement disclosing whether and how generative AI was used in the research and manuscript preparation process or state that it was not used.
References References must follow NLM style. References must be numbered consecutively in order of first mention and cited in the text with bracketed numbers in square brackets, with the reference list presented in numerical order.
Figures & Tables A maximum of five figures and five tables is permitted. Figures and structures must be supplied in separate files from the text, with figures submitted individually when there are several. References of particular interest must be marked with one or two asterisks and annotated with a brief sentence, and each table and figure must be numbered consecutively in the order of first citation in the text.
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Systematic Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract of no more than 200 words is required. Abstract must not exceed 200 words. Abstract must be structured. Abstract must use the headings Introduction, Methods, Results, and Conclusions.
Manuscript Body of the article must include the sections Introduction, Methods, Results, and Discussion, and an Expert Opinion section may be added. Manuscript must include 4 to 10 keywords in alphabetical order and include funding information, potential conflicts of interest, an author contribution statement, and registration details including registration number where applicable.
References References must follow NLM style. References must be numbered consecutively in order of first citation and listed at the end in numerical order with square-bracketed numbers, and important references must be highlighted with one or two asterisks and brief annotations.
Figures & Tables No more than 5 figures and no more than 5 tables are permitted. Figures and structures must be supplied in separate files from the text, and permission documentation for previously published figures must be uploaded alongside the manuscript. Tables and or plots must be used to support presentation of outcome data.
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Meta-Analyses

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required for this article type. Abstract must not exceed 200 words. Abstract must be structured. Abstract must use the headings Introduction, Methods, Results, and Conclusions.
Manuscript Manuscript body must include the sections Introduction, Methods, Results, and Discussion, and an Expert Opinion section may be added. Manuscript must include 4 to 10 keywords in alphabetical order, funding information, potential conflicts of interest, an author contribution statement, registration details including registration numbers where applicable, and a statement disclosing whether and how generative AI was used.
References Around 100 references are suggested for a full-length review. References must follow NLM style. References must be numbered consecutively in order of first citation, cited in square brackets, listed in numerical order, and important references must be marked with one or two asterisks and brief annotations.
Figures & Tables No more than 5 figures and no more than 5 tables are permitted. Figures must be supplied in separate files from the text and submitted individually when there are several figures. Tables or plots must be used to support presentation of outcome data, and permission documentation for any previously published figures must be uploaded alongside the manuscript.
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Letters To The Editor

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required. Abstract must be no more than 200 words. Abstract must be structured. Abstract must present the headings in this order: Introduction, Areas covered, and Expert Opinion/Commentary.
Manuscript Manuscript must be a maximum of 1500 words excluding references. Manuscript must include 5–8 keywords and the author's name, address, and contact details, and it must include a statement disclosing whether and how generative AI was used in the research and manuscript preparation process or state that it was not used.
References References must not exceed 15, and one reference must be the article under discussion. References must follow NLM style. References must be numbered consecutively in order of first mention and listed at the end in numerical order with square-bracketed citation numbers.
Figures & Tables Figures are not permitted and tables are not permitted. Figures must be supplied in separate files from the text if any are submitted, but this article type does not permit figures or tables.
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Recent Publications

The impact of novel bet inhibitors on the treatment armamentarium of Myelofibrosis

Matteo Bellia, Clara Deambrogi, Abdurraouf Mokhtar Mahmoud, Andrea Patriarca

10.1080/13543784.2026.2677662
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The journey of targeted drug conjugates in solid tumors: moving beyond antibody drug conjugates

Stephen Walsh, Francesca Wood, Leslie R. DeMars, Gavin Bennett

10.1080/13543784.2026.2683842
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Alpha-1 antitrypsin: therapeutic applications beyond serine protease inhibition

Martina Toldo, Trushaben Patel, Michele Golino, Eugenio Refrigeri, Jazmin Kelly, Antonio Abbate, Eleonora Mezzaroma, Stefano Toldo

10.1080/13543784.2026.2681588
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SOT201: cis -acting PD-1/IL-15 mutein-based immunocytokine under investigational study in solid tumors

Vladyslav Mazhara, Irfan Baki Kilic, Irena Adkins, Radek Spisek, Marek Kovar

10.1080/13543784.2026.2683841
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Discontinued therapies for sickle cell disease: status and future directions

Akshay Sharma, Shruthi Suryaprakash, Liza-Marie Johnson, Yoram Unguru

10.1080/13543784.2026.2663116
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Frequently asked questions

How long does it take to publish?

Accepted Author Version is published online in 3 days after acceptance if the copyright form has been received. Accelerated Publication Plus offers a final decision in as little as 3 weeks from submission, first proofs within 5 working days, and online publication usually 1-2 weeks after acceptance. Accelerated Publication offers a final decision in as little as 9 weeks from submission, first proofs within 5 working days, and online publication usually 2-3 weeks after acceptance.

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Is a cover letter required?

A separate cover sheet with authors’ names, affiliations, telephone number, and email address of the corresponding author is required.

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What are the publication costs?

Individual pricing available on request; institutional online-only subscription USD 13,870.00; institutional print and online subscription USD 20,309.00; local tax added as applicable.

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Research Topics

Monoclonal and Polyclonal Antibodies Research Diabetes Treatment and Management Asthma and respiratory diseases Lipoproteins and Cardiovascular Health HIV/AIDS drug development and treatment HER2/EGFR in Cancer Research Neurotransmitter Receptor Influence on Behavior Immunotherapy and Immune Responses Cancer Treatment and Pharmacology Angiogenesis and VEGF in Cancer Estrogen and related hormone effects Neuroscience and Neuropharmacology Research Rheumatoid Arthritis Research and Therapies Heart Failure Treatment and Management Peptidase Inhibition and Analysis Receptor Mechanisms and Signaling HIV Research and Treatment Antibiotic Resistance in Bacteria Chronic Lymphocytic Leukemia Research Blood Pressure and Hypertension Studies Metabolism, Diabetes, and Cancer Cholinesterase and Neurodegenerative Diseases Lung Cancer Treatments and Mutations Cancer therapeutics and mechanisms Neuropeptides and Animal Physiology