How long does it take to publish?

6 days submission to first decision; 35 days submission to decision after review; 33 days submission to acceptance.

Is a cover letter required?

A cover letter is required. It should confirm the manuscript has not been published or submitted elsewhere, describe each author's role, disclose other contributors, note similar published or submitted manuscripts, and confirm all authors agree to submission.

What are the publication costs?

Open access APC is USD 4420 excluding taxes for all articles. Subscription publication has no open access publication fee.

Fertility and Sterility - Submission Guidelines & Formatting

Clinical Trial

Cover Letter A cover letter is required. The cover letter must state that the manuscript has not been published or submitted elsewhere, detail each author's role, disclose other contributors and similar manuscripts, include copies of similar manuscripts, and confirm all authors agree to submission.

Abstract A structured abstract is required. The abstract target word limit is 350 words. The abstract must be structured. The structured abstract must include the headings Objective, Design, Subjects, Intervention, Main Outcome Measures, Results, and Conclusion, and it must report the primary outcome.

Manuscript The text must not exceed 3,500 words, excluding the running title, cover page, capsule, abstract, and references. The manuscript must include the sections Introduction, Materials and Methods, Results, Discussion, and Conclusions. The submission must include a 30-word-or-less capsule, 3 to 5 keywords after the abstract, a declaration of any generative AI use before the references, and the manuscript must clearly state the primary hypothesis, classify outcomes as primary, secondary, or exploratory, report inclusion and exclusion criteria, describe the intervention, blinding, and allocation, list protocol or statistical plan deviations, report target and final sample sizes, provide trial dates, label post hoc analyses, report adverse events, and address published literature and study limitations in the discussion.

References References must follow the Uniform Requirements style. References must be numbered consecutively in order of first text citation, list up to six authors followed by et al. when applicable, and use Index Medicus journal abbreviations.

Figures & Tables A combined maximum of 4 total figures and tables is allowed. Figure captions must be supplied separately after the references, and tables must be placed at the end of the manuscript file following the figure legends or reference list. Tables must be submitted as editable text rather than images.

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Cohort Study

Cover Letter A cover letter is required. The cover letter must state that the manuscript is not published or under consideration elsewhere, detail each author's role, disclose other contributors, note similar manuscripts and include copies of them, and confirm all authors agree to submission.

Abstract A structured abstract is required. The abstract target word limit is 350 words. The abstract must be structured. The abstract must include the headings Objective, Design, Subjects, Exposure, Main Outcome Measures, Results, and Conclusion.

Manuscript The text word limit is 3,500 words excluding the running title, cover page, capsule, abstract, and references. The manuscript must include Introduction, Materials and Methods, Results, Discussion, and Conclusions, with the discussion placing results in context with the published literature and addressing study limitations. The submission must include a 30-word-or-less complete-sentence capsule stating the paper’s final conclusion, 3 to 5 keywords after the abstract, an AI-use declaration before the references when applicable, and the manuscript must clearly state whether the cohort study is prospective or retrospective with the a priori hypothesis, population details including inclusion and exclusion criteria, study setting and dates, clearly defined exposures and outcomes with primary, secondary, or exploratory designation when multiple, data source and validation methods, available and unavailable confounding variables, sample size or power rationale, missing data handling, and crude and adjusted associations with 95% confidence intervals.

References References must follow the Uniform Requirements style. References must be numbered consecutively in order of first citation, list up to six authors followed by et al. when applicable, and use Index Medicus journal abbreviations.

Figures & Tables A combined maximum of 4 total figures and tables is allowed. Figure captions must be provided separately after the references, and tables must be placed at the end of the manuscript file following the figure legends or reference list. Tables must be submitted as editable text rather than images.

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Case-Control Study

Cover Letter A cover letter is required. The cover letter must state that the manuscript has not been published or submitted elsewhere, detail each author's role, disclose other contributors, note similar manuscripts and include copies of them, and confirm all authors agree to submission.

Abstract A structured abstract is required. The abstract target word limit is 350 words. The abstract must be structured. The structured abstract must include the headings Objective, Design, Subjects, Exposure, Main Outcome Measures, Results, and Conclusion.

Manuscript The text is limited to 3,500 words, excluding the running title, cover page, capsule, abstract, and references. The manuscript must include Introduction, Materials and Methods, Results, Discussion, and Conclusions, and the study design must be stated as prospective or retrospective with an a priori hypothesis. The submission must include a capsule of 30 words or less stating the paper’s final conclusion, 3 to 5 keywords after the abstract, an AI-use declaration before the references when applicable, and the discussion must contextualize results in the literature and address study limitations.

References References must follow the Uniform Requirements style. References must be numbered consecutively in order of first citation, list up to six authors before et al., and use Index Medicus journal abbreviations.

Figures & Tables A combined maximum of 4 figures and tables is allowed. Figure captions must be provided separately after the references, and tables must be placed at the end of the manuscript file following the figure legends or reference list. Tables must be submitted as editable text, not images, and numbered consecutively according to their appearance in the text.

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Other Observational Study

Cover Letter A cover letter is required. The cover letter must state that the manuscript is not published or under consideration elsewhere, detail each author's role, disclose other contributors, note similar manuscripts and include copies of them, and confirm all authors agree to submission.

Abstract A structured abstract is required. The abstract target word limit is 350 words. The abstract must be structured. The structured abstract must include the headings Objective, Design, Subjects, Exposure, Main Outcome Measures, Results, and Conclusion.

Manuscript The text limit is 3,500 words, excluding the running title, cover page, capsule, abstract, and references. The manuscript must include Introduction, Materials and Methods, Results, Discussion, and Conclusions, clearly state an objective or hypothesis and design and methods, and the discussion must place results in context with the literature and address study limitations. The submission must include a capsule of 30 words or less stating the paper's final conclusion, 3 to 5 keywords after the abstract, an acknowledgements section before the references, and an AI-use declaration before the references when applicable.

References References must follow the Uniform Requirements style. References must be numbered consecutively in order of first citation, list up to six authors followed by et al. when applicable, and use Index Medicus journal abbreviations.

Figures & Tables A combined maximum of 4 figures and tables is allowed. Figure captions must be provided separately after the references, and tables must be placed at the end of the manuscript file following the figure legends or reference list. Tables must be submitted as editable text and numbered consecutively in the order they appear in the text.

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Cost-Effectiveness Analysis

Cover Letter A cover letter is required. The cover letter must state that the manuscript has not been published or submitted elsewhere, detail each author's role, disclose other contributors, note any similar manuscripts and include copies of them, and confirm all authors agree to submission.

Abstract A structured abstract is required. The abstract target word limit is 350 words. The abstract must be structured. The structured abstract must include the headings Objective, Design, Subjects, Intervention or Exposure as applicable, Main Outcome Measures, Results, and Conclusion.

Manuscript The text is limited to 3,500 words excluding the running title, cover page, capsule, abstract, and references. The manuscript must include Introduction, Materials and Methods, Results, Discussion, and Conclusions, clearly state an objective or hypothesis and design and methods, and the discussion must place results in context with the published literature and address study limitations. The submission must include a capsule of 30 words or less stating the paper’s final conclusion, 3 to 5 keywords after the abstract, and a declaration of any generative AI use in a section before the references when applicable.

References References must follow the Uniform Requirements style. References must be numbered consecutively in order of first citation, list up to six authors followed by et al. when applicable, and use Index Medicus journal abbreviations.

Figures & Tables A combined maximum of 4 figures and tables is allowed. Figure captions must be provided separately after the references, and tables must be placed at the end of the manuscript file following the figure legends or reference list. Tables must be submitted as editable text rather than images.

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Study Of Screening And Diagnostic Tests

Cover Letter A cover letter is required. The cover letter must state that the manuscript is unpublished and not under consideration elsewhere, detail each author's role, disclose other contributors and similar manuscripts, include copies of similar manuscripts, and confirm all authors agree to submission.

Abstract A structured abstract is required. The abstract target word limit is 350 words. The abstract must be structured. The structured abstract must include the headings Objective, Design, Subjects, Intervention for randomized controlled trials or Exposure for observational studies, Main Outcome Measures, Results, and Conclusion.

Manuscript The text is limited to 3,500 words, excluding the running title, cover page, capsule, abstract, and references. The manuscript must include the sections Introduction, Materials and Methods, Results, Discussion, and Conclusions, clearly state an objective or hypothesis and the design and methods, and the discussion must place the results in context with the published literature and address study limitations. The submission must include a capsule of 30 words or fewer stating the paper’s final conclusion, 3 to 5 keywords after the abstract, and a declaration of generative AI use in scientific writing in a section before the references when applicable.

References References must follow the Uniform Requirements style. References must be numbered consecutively in order of first text citation, list up to six authors followed by et al. when applicable, use Index Medicus journal abbreviations, and omit issue numbers in parentheses after the volume.

Figures & Tables A combined maximum of 4 total figures and tables is allowed. Figure captions must be supplied separately on the manuscript page following the references, and tables must be placed at the end of the manuscript file following the figure legends or reference list. Tables must be submitted as editable text rather than images and numbered consecutively in the order they appear in the text.

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Comparative Effectiveness Research

Cover Letter A cover letter is required. The cover letter must state that the manuscript has not been published or submitted elsewhere, detail each author's role, disclose other contributors, note similar manuscripts and include copies of them, and confirm all authors agree to submission.

Abstract A structured abstract is required. The abstract target word limit is 350 words. The abstract must be structured. The abstract must include the headings Objective, Design, Subjects, Intervention for randomized controlled trials or Exposure for observational studies, Main Outcome Measures, Results, and Conclusion.

Manuscript The text is limited to 3,500 words excluding the running title, cover page, capsule, abstract, and references. The manuscript must include Introduction, Materials and Methods, Results, Discussion, and Conclusions, and it must clearly state an objective or hypothesis, clearly describe the design and methods, and ensure the discussion places the results in context with the published literature and addresses study limitations. The submission must include a 30-word-or-less capsule stating the paper's final conclusion, 3 to 5 keywords after the abstract, an acknowledgements section before the references, and a declaration of any generative AI use in scientific writing in a new section before the references when applicable.

References References must follow the Uniform Requirements style. References must be numbered consecutively in order of first text citation, list up to six authors followed by et al. when applicable, use Index Medicus journal abbreviations, and omit issue numbers after the volume.

Figures & Tables A combined maximum of 4 total figures and tables is allowed. Figure captions must be provided separately after the references, and tables must be placed at the end of the manuscript file following the figure legends or reference list. Tables must be submitted as editable text rather than images and numbered consecutively in the order they appear in the text.

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Genetic Association Study

Cover Letter A cover letter is required. The cover letter must state that the manuscript has not been published or submitted elsewhere, detail each author's role, disclose other contributors, note any similar manuscripts and include copies of them, and confirm all authors agree to submission.

Abstract A structured abstract is required. The abstract target word limit is 350 words. The abstract must be structured. The structured abstract must include the headings Objective, Design, Subjects, Intervention for randomized controlled trials or Exposure for observational studies, Main Outcome Measures, Results, and Conclusion.

Manuscript The text must not exceed 3,500 words, excluding the running title, cover page, capsule, abstract, and references. The manuscript must include Introduction, Materials and Methods, Results, Discussion, and Conclusions, clearly state an objective or hypothesis and the design and methods, present study setting and dates, participant criteria or data sources as applicable, describe interventions or exposures and outcomes, and discuss the results in the context of the literature with study limitations. The submission must include a capsule of 30 words or less stating the paper's final conclusion, 3 to 5 keywords after the abstract, an acknowledgements section before the references, and a declaration of any generative AI use in scientific writing in a section before the references when applicable.

References References must follow the Uniform Requirements style. References must be numbered consecutively in order of first text citation, list up to six authors followed by et al. when applicable, and use Index Medicus journal abbreviations.

Figures & Tables A combined maximum of 4 total figures and tables is allowed. Figure captions must be provided on a separate manuscript page after the references, and tables must be placed at the end of the manuscript file following the figure legends or reference list. Tables must be submitted as editable text rather than images.

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Cross Sectional Study

Cover Letter A cover letter is required. The cover letter must state that the manuscript has not been published or submitted elsewhere, detail each author's role, disclose other contributors, note any similar manuscripts with copies included, and confirm all authors agree to submission.

Abstract A structured abstract is required. The abstract target word limit is 350 words. The abstract must be structured. The abstract must include the headings Objective, Design, Subjects, Exposure, Main Outcome Measures, Results, and Conclusion.

Manuscript The text word limit is 3,500 words, excluding the running title, cover page, capsule, abstract, and references. The manuscript must include Introduction, Materials and Methods, Results, Discussion, and Conclusions, clearly state an objective or hypothesis and design and methods, present study setting and dates, participants with inclusion and exclusion criteria, participation or response rates or data sources and validation as applicable, describe exposures and main outcomes, and discuss the results in the context of the published literature with study limitations. The submission must include a 30-word-or-less capsule stating the paper’s final conclusion, 3 to 5 keywords after the abstract, an acknowledgements section before the references, and a declaration of generative AI use in a section before the references when applicable.

References References must follow the Uniform Requirements style. References must be numbered consecutively in order of first citation, include up to six authors followed by et al. when applicable, and use Index Medicus journal abbreviations.

Figures & Tables A combined maximum of 4 total figures and tables is allowed. Figure captions must be provided separately after the references, and tables must be placed at the end of the manuscript file following the figure legends or reference list. Tables must be submitted as editable text rather than images and numbered consecutively in the order they appear in the text.

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Systematic Review (With Meta-Analysis)

Cover Letter A cover letter is required. The cover letter must state that the manuscript is unpublished and not under consideration elsewhere, detail each author's role and any other contributors, note similar manuscripts with copies included, and confirm all authors agree to submission.

Abstract A structured abstract is required. The target abstract length is 350 words. The abstract must be structured. The structured abstract must include Importance, Objective, Data sources, Study selection and synthesis, Main outcomes, Results, and Conclusion and relevance.

Manuscript The text must not exceed 3,500 words, excluding the running title, cover page, capsule, abstract, and references. The manuscript must include Introduction, Materials and Methods, Results, Discussion, and Conclusions, and the subtitle must include "A Meta-analysis." The submission must include a capsule of 30 words or less, 3 to 5 keywords after the abstract, a section on the quality of the included literature, and a declaration of generative AI use before the references when applicable.

References References must follow the Uniform Requirements style. References must be numbered consecutively in order of first citation, list up to six authors followed by et al. when applicable, and use Index Medicus journal abbreviations.

Figures & Tables A maximum of 5 tables or figures is allowed. Figure captions must be provided separately after the reference list, and tables must be placed at the end of the manuscript file following the figure legends or reference list. Tables must be submitted as editable text rather than images and numbered consecutively in the order they appear in the text.

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Systematic Review (Without Meta-Analysis)

Cover Letter A cover letter is required. The cover letter must state that the manuscript has not been published or submitted elsewhere, detail each author's role, disclose other contributors, note similar manuscripts and include copies of them, and confirm all authors agree to submission.

Abstract A structured abstract is required. The abstract target word limit is 350 words. The abstract must be structured. The structured abstract must include the sections Importance, Objective, Evidence review, Findings, and Conclusion and relevance.

Manuscript The text must not exceed 3,500 words, excluding the running title, cover page, capsule, abstract, and references. The manuscript must include the sections Introduction, Materials and Methods, Results, Discussion, and Conclusions, and the subtitle must include "A Systematic review." The submission must include a capsule of 30 words or less stating the paper’s final conclusion, 3 to 5 keywords after the abstract, an acknowledgements section before the references, and an AI-use declaration before the references when applicable.

References References must follow the Uniform Requirements style. References must be numbered consecutively in order of first text citation, list up to six authors followed by et al. when applicable, and use Index Medicus journal abbreviations.

Figures & Tables A maximum of 5 tables or figures is allowed. Figure captions must be provided separately after the references, and tables must be placed at the end of the manuscript file following the figure legends or reference list. Tables must be submitted as editable text rather than images.

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Laboratory Based Study

Cover Letter A cover letter is required. The cover letter must state that the manuscript has not been published or submitted elsewhere, detail each author's role, disclose other contributors, note any similar manuscripts with copies included, and confirm all authors agree to submission.

Abstract A structured abstract is required. The abstract target word limit is 350 words. The abstract must be structured. The structured abstract must include the headings Objective, Design, Subjects, Intervention for randomized controlled trials or Exposure for observational studies, Main Outcome Measures, Results, and Conclusion.

Manuscript The text is limited to 3,500 words excluding the running title, cover page, capsule, abstract, and references. The manuscript must include Introduction, Materials and Methods, Results, Discussion, and Conclusions, with methods detailed enough for replication and a clear hypothesis or objective. The submission must include a 30-word-or-less capsule stating the paper's final conclusion, 3 to 5 keywords after the abstract, acknowledgements before the references, and a generative AI declaration before the references when applicable.

References References must follow the Uniform Requirements style. References must be numbered consecutively in order of first text citation, list up to six authors followed by et al. when applicable, and use Index Medicus journal abbreviations.

Figures & Tables A combined maximum of 4 total figures and tables is allowed. Figure captions must be provided on a separate page after the references, and tables must be placed at the end of the manuscript file following the figure legends or reference list. Tables must be submitted as editable text rather than images.

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Systematic Review

Cover Letter A cover letter is required. The cover letter must state that the manuscript has not been published or submitted elsewhere, detail each author's role, disclose other contributors, note similar manuscripts and include copies of them, and confirm all authors agree to submission.

Abstract A structured abstract is required. The abstract target word limit is 350 words. The abstract must be structured. The structured abstract must include the sections Importance, Objective, Evidence review, Findings, and Conclusion and relevance.

Manuscript The text must not exceed 3,500 words, excluding the running title, cover page, capsule, abstract, and references. The manuscript must include the sections Introduction, Materials and Methods, Results, Discussion, and Conclusions, and the subtitle must include "A Systematic review". The submission must include a capsule of 30 words or less stating the paper’s final conclusion, 3 to 5 keywords after the abstract, an acknowledgements section before the references, and a generative AI declaration before the references when applicable.

References References must follow the Uniform Requirements style. References must be numbered consecutively in order of first citation, list up to six authors followed by et al. when applicable, use Index Medicus journal abbreviations, include full details for abstract citations and web URLs with access dates, and omit issue numbers after the volume.

Figures & Tables A maximum of 5 tables or figures is allowed. Figure captions must be provided on a separate manuscript page after the references, and tables must be placed at the end of the manuscript file following the figure legends or reference list. Tables must be submitted as editable text, not images, and numbered consecutively in the order they appear in the text.

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Decision Analysis

Cover Letter A cover letter is required. The cover letter must confirm exclusive original submission, detail each author's role, disclose other contributors, note similar manuscripts or publications and include copies of similar manuscripts, and state that all authors agree to submission.

Abstract A structured abstract is required. The abstract target word limit is 350 words. The abstract must be structured. The structured abstract must include the headings Objective, Design, Subjects, Intervention for randomized controlled trials or Exposure for observational studies, Main Outcome Measures, Results, and Conclusion.

Manuscript The text is limited to 3,500 words, excluding the running title, cover page, capsule, abstract, and references. The manuscript must include Introduction, Materials and Methods, Results, Discussion, and Conclusions, and it must clearly state an objective or hypothesis, clearly present design and methods, and discuss the results in context with the literature and study limitations. The submission must include a 30-word-or-less capsule stating the paper’s final conclusions, 3 to 5 keywords immediately after the abstract, a separate acknowledgements section before the references, and a declaration of any generative AI use in scientific writing in a section placed before the references when applicable.

References References must follow the Uniform Requirements style. References must be numbered consecutively in order of first text citation, list up to six authors before adding et al., use Index Medicus journal abbreviations, omit issue numbers after the volume, include full details for any abstract citations, and give web references with the full URL and access date.

Figures & Tables A combined maximum of 4 figures and tables is allowed. Figure captions must be provided separately after the references, and tables must be placed at the end of the manuscript file following the figure legends or reference list. Tables must be submitted as editable text rather than images and numbered consecutively in the order they appear in the text.

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Quality Improvement Study

Cover Letter A cover letter is required. The cover letter must state that the manuscript has not been published or submitted elsewhere, detail each author's role, disclose other contributors, note similar manuscripts with copies included, and confirm all authors agree to submission.

Abstract A structured abstract is required. The abstract target word limit is 350 words. The abstract must be structured. The structured abstract must include the headings Objective, Design, Subjects, Intervention for randomized controlled trials or Exposure for observational studies, Main Outcome Measures, Results, and Conclusion.

Manuscript The text is limited to 3,500 words, excluding the running title, cover page, capsule, abstract, and references. The manuscript must include Introduction, Materials and Methods, Results, Discussion, and Conclusions, and it must clearly state an objective or hypothesis, design and methods, relevant setting and participant or data-source details, interventions or exposures, outcomes, and a discussion that places results in context with the literature and addresses limitations. The submission must include a capsule of 30 words or less stating the paper’s final conclusion, 3 to 5 keywords after the abstract, acknowledgements before the references, and a declaration of generative AI use in a section before the references when applicable.

References References must follow the Uniform Requirements style. References must be numbered consecutively in order of first citation, include up to six authors followed by et al. when applicable, and use Index Medicus journal abbreviations.

Figures & Tables A combined maximum of 4 total figures and tables is allowed. Figure captions must be provided on a separate manuscript page after the references, and tables must be placed at the end of the manuscript file following the figure legends or reference list. Tables must be submitted as editable text rather than images.

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Fertility and Sterility

Submission Instructions

Clinical Trial

Cohort Study

Case-Control Study

Other Observational Study

Cost-Effectiveness Analysis

Study Of Screening And Diagnostic Tests

Comparative Effectiveness Research

Genetic Association Study

Cross Sectional Study

Systematic Review (With Meta-Analysis)

Systematic Review (Without Meta-Analysis)

Laboratory Based Study

Systematic Review

Decision Analysis

Quality Improvement Study

Recent Publications

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Home Pregnancy Test Sensitivity by Test Timing and Cycle Length with Real-World Use Among Pregnancy Planners who Conceived

Systematic assessment of allele dropout in preimplantation genetic testing for monogenic disorders: Incidence, detection, and clinical testing strategies

Artificial intelligence in the in vitro fertilization laboratory: a committee opinion

Frequently asked questions

How long does it take to publish?

Is a cover letter required?

What are the publication costs?

Research Topics

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