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Frontiers in Systems Neuroscience

Frontiers in Systems Neuroscience is part of a neuroscience journal series and focuses on advancing understanding of whole systems of the brain, including the architecture of brain systems and information processing, storage, and retrieval.

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Subject Neurosciences
Impact Factor 3.5
Quartile Q2
Open Access Type Open
eISSN 1662-5137
Invitation Only No
Cost Range Article processing charges are CHF 3,150 for A-Type Articles and CHF 2,500 for B-Type Articles.

Submission Instructions

Frontiers in Systems Neuroscience accepts the following article types. Click on an article type to view submission instructions.

Original Research

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required. Abstract must be structured in a single paragraph.
Manuscript Manuscript must not exceed 12,000 words. Manuscript must be organized as Abstract, Introduction, Materials and Methods, Results, and Discussion. Manuscript must include at least five keywords, indicate the word count and number of figures and tables on the first page, and disclose any generative AI use in the acknowledgements and in the methods section if applicable.
References References must include all works cited, list the first six authors followed by et al. with authors’ given names abbreviated to initials, and include the DOI when available.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, and tables must be inserted directly into the manuscript at the end in editable form. Each figure and table must be cited in the text in numerical order.
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Systematic Review

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must be structured and presented as a single paragraph.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should be organized as Abstract, Introduction, Methods, Results, and Discussion, with the Methods including study design, participants, interventions, comparators, systematic review protocol, search strategy, data sources, study selection and data extraction, and data analysis, the Results including a flow diagram of retrieved studies, study selection and characteristics, synthesized findings, and assessment of risk of bias, and the Discussion including summary of main findings, limitations, and conclusions. Manuscript must clearly define the research question in PICOS terms, include funding information, contain at least five keywords, and acknowledge any use of generative AI in the acknowledgements and methods section if applicable with the tool name, version, model, and source.
References References must include only published or accepted articles, list the first six authors followed by et al. with authors’ given names abbreviated to initials, include DOI when available, ensure all in-text citations appear in the reference list and vice versa, and exclude unpublished material, submitted manuscripts, and personal communications.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, while tables must be directly inserted at the end of the manuscript in editable source form. Each figure and table must be cited in the text in numerical order, and figure panels should be labeled with capital letters.
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Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured in a single paragraph.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should be organized as Abstract, Introduction, subject-relevant subsections, and Discussion, and it must discuss different schools of thought or controversies, fundamental concepts, issues and problems, current research gaps, and potential developments in the field. Manuscript must include at least five keywords, indicate the number of words and figures and tables on the first page, acknowledge any generative AI use in the acknowledgements and methods if applicable with the tool name, version, model, and source, and include funding information in a funding section.
References References must include only published or accepted works, all cited items must appear in the reference list and vice versa, the first six authors should be listed followed by et al. with authors’ given names abbreviated to initials, DOI should be provided when available, and unpublished material including personal communications must not be included.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, while tables must be directly inserted at the end of the manuscript in editable source form. Each figure and table must be cited in the text in numerical order.
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Clinical Trial

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured in a single paragraph. Abstract must include the clinical trial registry number, unique identifier, and URL of the publicly accessible trial registry website.
Manuscript Manuscript must not exceed 12,000 words. Manuscript must be organized as Abstract, Introduction, Materials and Methods, Results, and Discussion. Manuscript must include acknowledgment of any generative AI use in the acknowledgments section and in the Methods section if applicable.
References References must list the first six authors followed by et al., abbreviate given names to initials, and include the DOI when available.
Figures & Tables Figures must be submitted individually, figure captions placed at the end of the manuscript, and tables inserted directly at the end of the manuscript in editable source form. Each figure and table must be cited in the text in numerical order.
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Mini Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured in a single paragraph.
Manuscript Manuscript must not exceed 3,000 words. Manuscript should be organized as Abstract, Introduction, subject-relevant subsections, and Discussion, and it must discuss different schools of thought or controversies, current research gaps, and potential future developments in the field. At least five keywords are required, and any use of generative AI to produce or edit written or visual content must be disclosed in the acknowledgements section and in the methods section if applicable, including the tool name, version, model, and source.
References References must include only published or accepted works, list the first six authors followed by et al. with author given names abbreviated to initials, include the DOI when available, and exclude unpublished material or personal communications.
Figures & Tables Mini Review articles may contain no more than 2 figures and/or tables. Figures must be submitted individually with captions placed at the end of the manuscript, while tables must be directly inserted at the end of the manuscript in editable form. Each figure and table must be cited in the text in numerical order, and figure panels should be labeled with capital letters.
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Data Report

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured in a single paragraph, for example following IMRAD format.
Manuscript Manuscript must not exceed 3,000 words. Manuscript must be organized as Introduction; Methods used to collect the data, including the data collection period, filters applied, and guidance on interpreting and reusing the dataset; and some analysis of the data, and it must not include Results or Discussion sections. Manuscript must include the dataset name, the database or repository where the dataset was submitted, a confidential peer-review link to the dataset that is updated to a public link before publication, at least five keywords, and an acknowledgement of any generative AI use with the tool name, version, model, and source, including in Methods if applicable.
References References must include all cited items only, list the first six authors followed by et al. with initials for given names and DOI when available, and include version and unique identifier for cited deposited datasets when available.
Figures & Tables No more than 2 figures and/or tables are permitted. Figures must be submitted individually with captions at the end of the manuscript, while tables must be inserted directly into the manuscript at the end in editable source form. Each figure and table must be cited in numerical order in the text, and multi-panel figures must use clearly labeled panels such as (A), (B), and (C).
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Brief Research Report

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured in a single paragraph.
Manuscript Manuscript must not exceed 4,000 words. Manuscript should be organized as Abstract, Introduction, Method, Results, and Discussion. Manuscript must include at least five keywords, indicate the manuscript word count and number of figures and tables on the first page, and acknowledge any generative AI use in the acknowledgments and methods section if applicable.
References References must include the first six authors followed by et al. and the DOI when available, with author given names abbreviated to initials.
Figures & Tables Manuscript may contain no more than 4 figures and tables in total. Figures must be submitted individually, with figure captions placed at the end of the manuscript, and tables inserted directly into the manuscript at the end in editable form. Each figure and table must be cited in the text in numerical order, and multi-panel figures should use labels such as (A), (B), and (C).
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Fair² Data

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured in a single paragraph, for example according to the IMRAD format.
Manuscript Manuscript is capped at 12,000 words. Manuscript must be organized by headings and subheadings. Manuscript must include at least five keywords and acknowledge any use of generative AI in the acknowledgements section and in the methods section if applicable, including the tool name, version, model, and source.
References References must list the first six authors followed by et al. when applicable and include the DOI when available.
Figures & Tables FAIR² Data articles may include up to 15 figures or tables. Figures must be submitted individually, figure captions placed at the end of the manuscript, and tables inserted directly into the manuscript. Figures and tables must be cited in numerical order in the text, and figures with multiple panels must use labels such as (A), (B), and (C).
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Recent Publications

The neurobiological basis of the awe experience in affective disorders: an exploratory EEG study

Elena Bondi, Flavia Carbone, Giandomenico Schiena, Yara Massalha, MariaPia Marra, Lorena Di Consoli, Maddalena Mazzocut-Mis, Andrea Gaggioli, Alice Chirico, Paolo Brambilla, Eleonora Maggioni

10.3389/fnsys.2026.1805778
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Exploring the spiking neural autoencoder: from hyperexcitability to noise-driven compensation

Mohammadreza Khodashenas, Daniel P. Martins

10.3389/fnsys.2026.1788937
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Circuit dynamics of binocular conflict in mouse primary visual cortex

Daniel P. Montgomery, Daniel A. Bowen, Jin Wu, Mark F. Bear, Eric D. Gaier

10.3389/fnsys.2026.1786396
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Continuous bidirectional coupling of heart rate variability and emotions in dyad speaker-listener dynamics reveals unique interpersonal synchronization

Mohanad Alkhodari, Ioannis Ziogas, Jaskeerat Singh, Paolo Grigolini, Glenn W. Muschert, Fedor Kusmartsev, Herbert F. Jelinek

10.3389/fnsys.2026.1802891
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A novel 1-channel EEG marker may associate with perioperative cognitive change

Dana Baron Shahaf, Gil Bolotin, Oved Cohen, Mahli Raad, Raphael Derman, Goded Shahaf

10.3389/fnsys.2026.1688834
View Publication

Frequently asked questions

How long does it take to publish?

Is a cover letter required?

A traditional cover letter is not allowed. Authors must instead prepare a 200-word statement describing the manuscript's contribution to the field.

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What are the publication costs?

Article processing charges are CHF 3,150 for A-Type Articles and CHF 2,500 for B-Type Articles. APCs apply to articles that pass peer review and are accepted for publication.

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Research Topics

Neural dynamics and brain function Neuroscience and Neuropharmacology Research Functional Brain Connectivity Studies EEG and Brain-Computer Interfaces Memory and Neural Mechanisms Visual perception and processing mechanisms Neuroscience and Neural Engineering Neural and Behavioral Psychology Studies Photoreceptor and optogenetics research Neurological disorders and treatments Neurobiology and Insect Physiology Research Vestibular and auditory disorders Neural Networks and Applications Sleep and Wakefulness Research Advanced Memory and Neural Computing Hearing Loss and Rehabilitation Hearing, Cochlea, Tinnitus, Genetics Neuroscience and Music Perception Transcranial Magnetic Stimulation Studies Olfactory and Sensory Function Studies Retinal Development and Disorders Receptor Mechanisms and Signaling Neurotransmitter Receptor Influence on Behavior Multisensory perception and integration stochastic dynamics and bifurcation