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Infection And Immunity

Infection and Immunity is an ASM journal publishing research and minireviews in areas including bacteriology, immunology, host-microbial interactions, antimicrobial chemotherapy, veterinary microbiology, molecular and cellular biology, and the human microbiome.

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Impact Factor 2.8
Quartile Q3
Open Access Type Open
ISSN 0019-9567
eISSN 1098-5522
Invitation Only No
Cost Range ASM doesn’t charge a submission fee. Publication fees apply, and some article types do not have a fee.

Submission Instructions

Infection And Immunity accepts the following article types. Click on an article type to view submission instructions.

Research Articles

Cover Letter A cover letter is required for initial submissions.
Abstract An abstract is required. Abstract must be limited to 250 words or fewer. Abstract must be unstructured. Abstract must concisely summarize the paper, avoid abbreviations and references, exclude diagrams, and include a succinct description of the microbe and its associated disease.
Manuscript Manuscript must include a title page and sections including Introduction, Materials and Methods, Results, Acknowledgments, and References, with a Data availability paragraph at the end of Materials and Methods. Manuscript must include keywords and research areas at submission, and the title page must include the title, running title, author names, affiliations, corresponding author email addresses, and any required present-address or co-first-author footnotes.
References References must use a numbered citation style in citation order. References must be numbered in the order cited, cited parenthetically by number in sequential order in the text, list all authors and editors without using "et al.," use PubMed journal abbreviations without periods, and include URLs for accession numbers and code or software citations.
Figures & Tables Tables may be included in the manuscript file, and figures may be included in the Word file or uploaded separately at initial submission. Figures and tables must be numbered in citation order, all must be cited in the text, tabular data must include standard deviation or standard error values and replicate counts, and appendix figures and tables must be labeled with an "A" prefix.
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Minireviews

Cover Letter A cover letter is required. Cover letter must state whether the article was solicited and by whom.
Abstract An abstract is required. Abstract must be 250 words or fewer.
Manuscript Manuscript must be limited to 6,000 words excluding references. Content must be based on published articles. Keywords and research areas must be included, and biographical text must appear after the References section in the same manuscript file.
References References must be numbered in citation order, cited parenthetically by number in sequential order in the text, include all authors and editors without using "et al.", use PubMed journal abbreviations without periods in abbreviated words, and list only works cited in the text while unpublished data, submitted manuscripts, personal communications, and websites are cited parenthetically in the text instead of listed in the References section.
Figures & Tables Tables may be incorporated into the main submission file, and figures may be included in the manuscript file or uploaded separately at initial submission. Bio photos must be provided as black-and-white passport-size head shots with filenames containing the author's name or enough of it for identification.
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Letters To The Editor

Cover Letter A cover letter is required. Cover letter must state the article's DOI, the title of the article, and the last name of the first author.
Abstract Abstracts are not permitted.
Manuscript Letter must be no more than 500 words long, exclusive of references. Letter must be intended only for comments on articles published in the journal. Title must appear on the manuscript and on the submission form.
References References must be numbered in the order cited, include all authors and editors without using "et al.," use PubMed journal abbreviations without periods in abbreviated words, include URLs for database accession number and code or software citations, list only cited references in the References section, and place unpublished data, submitted manuscripts, personal communications, and websites in parenthetical text citations instead.
Figures & Tables Figures and tables should be kept to a minimum. Figures may be included in the Word file or uploaded separately at initial submission.
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Matters Arising

Cover Letter Cover letter is required for initial submissions.
Abstract An abstract is required. Abstract section is required.
Manuscript Submission should not exceed 1,200 words. Submission must include an Abstract section and an Importance section.
References Submission should not exceed 25 references. References must be numbered in citation order, include all authors' and editors' names without using "et al.", list only cited eligible source types in the References section, abbreviate journal names according to the PubMed Journals Database without periods in abbreviated words, provide URLs for database accession numbers and code or software citations, and cite unpublished data, submitted manuscripts, personal communications, and websites parenthetically in the text rather than in the References section.
Figures & Tables Submission may include no more than 2 tables.
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Commentaries

Cover Letter A cover letter is required for initial submissions.
Abstract An abstract is required. Abstract is limited to 75 words.
Manuscript Manuscripts must not exceed 4,000 words. Format must follow that of a Minireview. Keywords and research areas must be included.
References References must be numbered in citation order, cited parenthetically by number in sequential order in the text, include all authors and editors without using “et al.,” and use PubMed journal abbreviations without periods in abbreviated words.
Figures & Tables Tables may be incorporated into the manuscript file, and figures may be included in the manuscript file or uploaded separately at initial submission.
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Recent Publications

Lipidated Protein D vaccination elicits humoral and cellular responses and protects mice against challenge with non-typeable Haemophilus influenzae

Terri C. Thayer, Andrew Cox, Eduardo Gonzalez, Jill Mangiafesto, Lei Xu, Michael Pichichero, Ravinder Kaur

10.1128/iai.00647-25
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Immune evasion by a chytrid fungus includes inhibition of macrophage phagocytosis

Louise A. Rollins-Smith, Mitchell Le Sage, Chelsea Roach Simoneau, Somya Singh, Muhammad Riadul Haque Hossainey, Carlos Henrique Serezani, Leon Grayfer

10.1128/iai.00591-25
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Calcineurin-responsive zinc finger 1 (Crz1) contributes to stress tolerance and virulence in the pathogenic fungus Trichosporon asahii

Yuta Shimizu, Yasuhiko Matsumoto, Takashi Sugita

10.1128/iai.00759-25
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Nicotinamide attenuates the virulence of colorectal cancer-associated Fusobacterium nucleatum

Ziyi Yang, Zixue Lei, Qizhao Ma, Jumei Zeng, Mai Xu, Dian Zhang, Pei Xu, Kai Li, Tao Gong, Yuqing Li

10.1128/iai.00488-25
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Aspartate aminotransferase is required for Salmonella expansion in the inflamed gut via TCA anaplerosis

N. G. Shealy, M. Baltagulov, H. F. Avalos, J. Olivas, K. M. Jones, M. X. Byndloss

10.1128/iai.00161-26
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Frequently asked questions

How long does it take to publish?

Median time to first peer review decision is 34.5 days.

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Is a cover letter required?

A cover letter is required for Letters to the Editor and should state the article DOI, article title, and the last name of the first author. For Minireviews, the cover letter should state whether the article was solicited and by whom.

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What are the publication costs?

ASM doesn’t charge a submission fee. Publication fees apply, and some article types do not have a fee.

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Research Topics

Escherichia coli research studies Immune Response and Inflammation Bacterial Infections and Vaccines Streptococcal Infections and Treatments Pneumonia and Respiratory Infections Vibrio bacteria research studies Viral gastroenteritis research and epidemiology Bacterial Genetics and Biotechnology Vector-borne infectious diseases Antimicrobial Resistance in Staphylococcus Clostridium difficile and Clostridium perfringens research Bacteriophages and microbial interactions Salmonella and Campylobacter epidemiology Toxin Mechanisms and Immunotoxins Reproductive tract infections research Oral microbiology and periodontitis research Antifungal resistance and susceptibility Microbial infections and disease research Antimicrobial Peptides and Activities Bacterial biofilms and quorum sensing Mycobacterium research and diagnosis Antibiotic Resistance in Bacteria Immune Cell Function and Interaction Tuberculosis Research and Epidemiology Fungal Infections and Studies