NR

Nature reviews. Immunology

Nature Reviews Immunology is a journal in the Nature Reviews portfolio covering immunology research and commentary, with content including Review Articles, Research Highlights, Journal Club pieces, Comments, World View articles and collections.

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Subject Immunology
Impact Factor 60.9
Quartile Q1
Open Access Type Hybrid
ISSN 1474-1733
eISSN 1474-1741
Invitation Only Yes
Cost Range Subscription publication route only; no immediate gold open access publication option.

Submission Instructions

Nature reviews. Immunology is an invitation-only journal. Submissions are accepted by invitation from the editorial board only. The following article types are accepted:

Review

Cover Letter Cover Letter requirements are not specified.
Abstract An unstructured abstract is required and should ideally be no more than 200 words. Abstract should ideally be a maximum of 200 words. Abstract must be unstructured.
Manuscript Manuscript should begin with an introduction without subheadings, use no more than three heading levels, and end with a brief concluding summary section without subheadings. Review articles may include review criteria only, must include an LLM use declaration in the Methods or another suitable section if applicable, and key points are not allowed for Nature Reviews Immunology.
References Reference density should be approximately 25 references per 1,000 words. References must use Nature Reviews style. References must be cited as sequential superscript numbers, listed in the order of main text, tables, figures, and boxes, and for works with six or more authors only the first author should be listed followed by 'et al.'.
Figures & Tables No more than 7 display items, including tables, figures, and boxes, are allowed. Tables and boxes must be provided as part of the article document. Display items must be cited in the main text in order, each figure must have a short title and concise legend with abbreviations defined, and tables must have a short title and no legend.
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Consensus Statement

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required and must be unstructured. Abstract should ideally be a maximum of 200 words. Abstract must be unstructured. Abstract must contain no references or display item citations.
Manuscript Manuscript must begin with an introduction without subheadings, include a Methods section describing methodology and relevant search strategy, decision-making process, inclusion criteria, exclusion criteria, and stakeholder details, and end with a brief summary section without subheadings. Use of an LLM must be documented in the Methods section or in a suitable alternative part of the manuscript.
References References should be approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited as superscript numbers sequentially in the order of main text, tables, figures, and then boxes, and references with six or more authors should list only the first author followed by 'et al.'.
Figures & Tables A maximum of 7 display items, including tables, figures and boxes, is allowed. Tables and boxes must be provided as part of the article document, while tables containing graphical content must be provided as separate image files. Tables must have a short title with all abbreviations defined and every cell completed, and figures must have a short title, a concise legend of about 200 words defining all abbreviations, and be fully labelled.
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Evidence-Based Guidelines

Cover Letter Cover Letter requirements are not specified.
Abstract An unstructured abstract is required. Abstract should ideally be a maximum of 200 words. Abstract must be unstructured.
Manuscript The article must include an introduction without subheadings, a Methods section describing methodology and stakeholders, and end with a brief summary section without subheadings. Use of an LLM must be documented in the Methods section or another suitable part of the manuscript, and no more than seven display items including tables, figures, and boxes are allowed.
References References should be approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited as sequential superscript numbers in the order of main text, tables, figures, and then boxes, and references with six or more authors should list only the first author followed by 'et al.'.
Figures & Tables A maximum of 7 display items, including tables, figures and boxes, is allowed. Tables and boxes must be provided as part of the article document, while tables containing graphical content must be provided as separate image files. Tables must have a short title, define all abbreviations, and have every cell completed, while figures must be fully labelled with a short title and a concise legend defining all abbreviations.
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Correspondence

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Main text must not exceed 500 words. The first paragraph must cite the original article and no more than two levels of headings are allowed. Competing interests must be included in the manuscript file, and any use of an LLM must be documented in the Methods section or another suitable part of the manuscript.
References Articles must contain no more than 10 references. References must use Nature Reviews reference style. References must be cited as superscript numbers in sequential order through the main text, tables, figures, then boxes, listed at the end of the article, and for works with six or more authors only the first author should be listed followed by 'et al.'.
Figures & Tables Only one display item may be included, consisting of a table, figure or box, and it should be discussed with the editor first. Tables and boxes must be provided as part of the article document, while tables containing graphical content must be provided as separate image files. Tables must have a short title and at least three columns of data, and each figure and box must have a short title.
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Recent Publications

LAG3 checkpoint function and its mechanism of action in therapeutic targeting

Yong Jiang, Dario A. A. Vignali, Haopeng Wang

10.1038/s41577-026-01359-2
View Publication

Metastasizing cancer cells leave an immunogenic trail

Yvonne Bordon

10.1038/s41577-026-01366-3
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A guide to B cell metabolism

Yavuz F. Yazicioglu, Glenn R. Bantug, Christoph Hess, Alexander J. Clarke

10.1038/s41577-026-01355-6
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Sympathetic nerve activity primes susceptibility to autoimmune hair loss

Kirsty Minton

10.1038/s41577-026-01365-4
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The next big questions in immunology

-

10.1038/s41577-026-01353-8
View Publication

Frequently asked questions

How long does it take to publish?

Accepted manuscripts may be self-archived for public release 6 months after first publication.

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What are the publication costs?

Research Topics

Immune Cell Function and Interaction T-cell and B-cell Immunology Immunotherapy and Immune Responses Immune Response and Inflammation Immune cells in cancer CAR-T cell therapy research interferon and immune responses IL-33, ST2, and ILC Pathways SARS-CoV-2 and COVID-19 Research Inflammasome and immune disorders Cancer Immunotherapy and Biomarkers Immune responses and vaccinations Phagocytosis and Immune Regulation Neuroinflammation and Neurodegeneration Mechanisms Neutrophil, Myeloperoxidase and Oxidative Mechanisms Gut microbiota and health COVID-19 Clinical Research Studies Monoclonal and Polyclonal Antibodies Research Cytokine Signaling Pathways and Interactions Asthma and respiratory diseases HIV Research and Treatment Diabetes and associated disorders Reproductive System and Pregnancy vaccines and immunoinformatics approaches Cytomegalovirus and herpesvirus research

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