Overview
Submission Instructions
Recent Publications
Frequently Asked Questions
Research Topics
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Nature Reviews Immunology is a journal in the Nature Reviews portfolio covering immunology research and commentary, with content including Review Articles, Research Highlights, Journal Club pieces, Comments, World View articles and collections.
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Subject
Immunology
Impact Factor
60.9
Quartile
Q1
Open Access Type
Hybrid
ISSN
1474-1733
eISSN
1474-1741
Invitation Only
Yes
Cost Range
Subscription publication route only; no immediate gold open access publication option.
Submission Instructions
Nature Reviews Immunology is an invitation-only journal. Submissions are accepted by invitation from the editorial board only. The following article types are accepted:
Review
Cover Letter
Cover Letter requirements are not specified.
Abstract
An unstructured abstract is required and should ideally be no more than 200 words. Abstract should ideally be a maximum of 200 words. Abstract must be unstructured.
Manuscript
Manuscript should begin with an introduction without subheadings, use no more than three heading levels, and end with a brief concluding summary section without subheadings. Review articles may include review criteria only, must include an LLM use declaration in the Methods or another suitable section if applicable, and key points are not allowed for Nature Reviews Immunology.
References
Reference density should be approximately 25 references per 1,000 words. References must use Nature Reviews style. References must be cited as sequential superscript numbers, listed in the order of main text, tables, figures, and boxes, and for works with six or more authors only the first author should be listed followed by 'et al.'.
Figures & Tables
No more than 7 display items, including tables, figures, and boxes, are allowed. Tables and boxes must be provided as part of the article document. Display items must be cited in the main text in order, each figure must have a short title and concise legend with abbreviations defined, and tables must have a short title and no legend.
Consensus Statement
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract is required and must be unstructured. Abstract should ideally be a maximum of 200 words. Abstract must be unstructured. Abstract must contain no references or display item citations.
Manuscript
Manuscript must begin with an introduction without subheadings, include a Methods section describing methodology and relevant search strategy, decision-making process, inclusion criteria, exclusion criteria, and stakeholder details, and end with a brief summary section without subheadings. Use of an LLM must be documented in the Methods section or in a suitable alternative part of the manuscript.
References
References should be approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited as superscript numbers sequentially in the order of main text, tables, figures, and then boxes, and references with six or more authors should list only the first author followed by 'et al.'.
Figures & Tables
A maximum of 7 display items, including tables, figures and boxes, is allowed. Tables and boxes must be provided as part of the article document, while tables containing graphical content must be provided as separate image files. Tables must have a short title with all abbreviations defined and every cell completed, and figures must have a short title, a concise legend of about 200 words defining all abbreviations, and be fully labelled.
Evidence-Based Guidelines
Cover Letter
Cover Letter requirements are not specified.
Abstract
An unstructured abstract is required. Abstract should ideally be a maximum of 200 words. Abstract must be unstructured.
Manuscript
The article must include an introduction without subheadings, a Methods section describing methodology and stakeholders, and end with a brief summary section without subheadings. Use of an LLM must be documented in the Methods section or another suitable part of the manuscript, and no more than seven display items including tables, figures, and boxes are allowed.
References
References should be approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited as sequential superscript numbers in the order of main text, tables, figures, and then boxes, and references with six or more authors should list only the first author followed by 'et al.'.
Figures & Tables
A maximum of 7 display items, including tables, figures and boxes, is allowed. Tables and boxes must be provided as part of the article document, while tables containing graphical content must be provided as separate image files. Tables must have a short title, define all abbreviations, and have every cell completed, while figures must be fully labelled with a short title and a concise legend defining all abbreviations.
Correspondence
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract requirements are not specified.
Manuscript
Main text must not exceed 500 words. The first paragraph must cite the original article and no more than two levels of headings are allowed. Competing interests must be included in the manuscript file, and any use of an LLM must be documented in the Methods section or another suitable part of the manuscript.
References
Articles must contain no more than 10 references. References must use Nature Reviews reference style. References must be cited as superscript numbers in sequential order through the main text, tables, figures, then boxes, listed at the end of the article, and for works with six or more authors only the first author should be listed followed by 'et al.'.
Figures & Tables
Only one display item may be included, consisting of a table, figure or box, and it should be discussed with the editor first. Tables and boxes must be provided as part of the article document, while tables containing graphical content must be provided as separate image files. Tables must have a short title and at least three columns of data, and each figure and box must have a short title.
Recent Publications
Calibrating T cell responsiveness through interactions with self
Judith N. Mandl, Heather J. Melichar, Byron B. Au-Yeung, Johannes Textor, Ludger Klein
10.1038/s41577-026-01305-2
View Publication
Comparative insights into the apoptosome, inflammasomes and PIDDosome
Mohamed Lamkanfi, Lieselotte Vande Walle, Felix Eichin, Andreas Villunger
10.1038/s41577-026-01304-3
View Publication
T cell-derived extracellular vesicles promote antitumour immunity through horizontal gene transfer
Kirsty Minton
10.1038/s41577-026-01309-y
View Publication
Immune regulation by erythroid cells: how erythroid progenitor cells and mature red blood cells shape immunity
Shokrollah Elahi
10.1038/s41577-026-01303-4
View Publication
CRISPR screen reveals regulators of age-associated CD8+ T cell dysfunction in cancer
Matthew Bianca, Tracy McGaha
10.1038/s41577-026-01308-z
View Publication
Frequently asked questions
How long does it take to publish?
Accepted manuscripts may be self-archived for public release 6 months after first publication.
Reformat to Nature Reviews Immunology using Livewrite PremiumWhat are the publication costs?
Hybrid journal.
Reformat to Nature Reviews Immunology using Livewrite PremiumResearch Topics
Immune Cell Function and Interaction
T-cell and B-cell Immunology
Immunotherapy and Immune Responses
Immune Response and Inflammation
Immune cells in cancer
CAR-T cell therapy research
interferon and immune responses
IL-33, ST2, and ILC Pathways
SARS-CoV-2 and COVID-19 Research
Inflammasome and immune disorders
Cancer Immunotherapy and Biomarkers
Immune responses and vaccinations
Phagocytosis and Immune Regulation
Neuroinflammation and Neurodegeneration Mechanisms
Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Gut microbiota and health
COVID-19 Clinical Research Studies
Monoclonal and Polyclonal Antibodies Research
Cytokine Signaling Pathways and Interactions
Asthma and respiratory diseases
HIV Research and Treatment
Diabetes and associated disorders
Reproductive System and Pregnancy
vaccines and immunoinformatics approaches
Cytomegalovirus and herpesvirus research