LS

Life Sciences

Life Sciences is an international journal publishing articles that emphasize the molecular, cellular, and functional basis of therapy. It focuses on mechanistic understanding relevant to human disease and translation to patients, favors full-length papers using modern scientific technologies to explain molecular, cellular, and physiological mechanisms, welcomes reviews of broad interest in the life sciences, and considers novel preclinical findings of biological significance to human disease while generally not encouraging clinical trial reports.

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Subject Medicine, Research & Experimental, Pharmacology & Pharmacy
Impact Factor 5.1
Quartile Q1
Open Access Type Hybrid
ISSN 0024-3205
eISSN 1879-0631
Invitation Only No
Cost Range USD 3950 APC for all open access articles; no open access publication fee for subscription articles.

Submission Instructions

Life Sciences accepts the following article types. Click on an article type to view submission instructions.

Original Research Articles

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 250 words. Abstract must be unstructured. Abstract must briefly state the purpose of the research, principal results, and major conclusions.
Manuscript Manuscript must be divided into clearly defined sections with Results and Discussion presented as separate sections. The submission must include 1 to 7 keywords, article highlights of 3 to 5 bullet points, and declarations including any generative AI statement before the references and reproducible AI methods details in the methods section when applicable.
References References must be cited using numerical citations in square brackets. References must be numbered in the order of appearance and include author names, source title, article or chapter title, year, volume, and article number or pagination where applicable.
Figures & Tables Figures must be uploaded as separate files, while tables must be submitted as editable text. All figures and tables must be cited in the text, numbered consecutively in order of appearance, and provided with captions.
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Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 250 words.
Manuscript Main text excluding references must not exceed 5,500 words, and this count includes text, displayed math, figures, and tables. Manuscript must be divided into clearly defined sections using headings, with Results and Discussion presented as separate sections. Submission must include 1 to 7 keywords in English and article highlights provided as a separate editable file containing 3 to 5 bullet points of no more than 85 characters each, and any use of generative AI in manuscript preparation must be declared in a new section before the references list.
References References must not exceed 100. Citations must be indicated by numbers in square brackets and references must be numbered in the order they appear in the article.
Figures & Tables Figures must be supplied as separate files, while tables must be submitted as editable text. All figures and tables must be cited in the text, numbered consecutively in order of appearance, and provided with captions.
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Recent Publications

Editorial Board

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10.1016/s0024-3205(26)00540-0
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Editorial Board

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10.1016/s0024-3205(26)00503-5
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Orai3 deficiency drives atrial remodeling and fibrillation susceptibility via Orai channel remodeling and SOCE hyperactivation

Xiaohe Wu, Yangcheng Xue, Haoyang Lu, Yanlong Cao, Danni Li, Ao Liang, Peiyang Zheng, Ran Zhang, Zhuoran Jia, Ren Zhao

10.1016/j.lfs.2026.124740
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β-Hydroxybutyrate alleviates intestinal aGVHD via remodeling gut microbiota-bile acid axis and inhibiting TLR4-NF-κB-driven Th1/Th17 differentiation

Ruixue Tian, Chao Deng, Kexin Liu, Hurong Lai, Caifeng Liao, Huaijun Tu, Jian Li

10.1016/j.lfs.2026.124737
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Porphyromonas gingivalis lipopolysaccharide induces osteoblast senescence and defective mineralization associated with indoleamine 2,3-dioxygenase 1–kynurenine–aryl hydrocarbon receptor signaling

Shuguang Han, Wenlong Zhang, Xiaoli Zhang, Mingyong Wang, Yu Jiang

10.1016/j.lfs.2026.124741
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Frequently asked questions

How long does it take to publish?

6 days from submission to first decision; 37 days from submission to decision after review; 91 days from submission to acceptance; 3 days from acceptance to online publication.

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What are the publication costs?

USD 3950 APC for all open access articles; no open access publication fee for subscription articles.

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Research Topics

Receptor Mechanisms and Signaling Neuroscience and Neuropharmacology Research Neuropeptides and Animal Physiology Neurotransmitter Receptor Influence on Behavior Nitric Oxide and Endothelin Effects Ion channel regulation and function Pain Mechanisms and Treatments Stress Responses and Cortisol Adipose Tissue and Metabolism Neuroendocrine regulation and behavior Human auditory perception and evaluation Diverse Scientific and Economic Studies Educational Robotics and Engineering Pharmacological Receptor Mechanisms and Effects Pancreatic function and diabetes Drug Transport and Resistance Mechanisms Regulation of Appetite and Obesity Circadian rhythm and melatonin Biochemical effects in animals Eicosanoids and Hypertension Pharmacology Cardiac electrophysiology and arrhythmias Neuroscience of respiration and sleep Diet and metabolism studies Hypothalamic control of reproductive hormones Cardiac Ischemia and Reperfusion

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