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Pharmacological Reviews

Pharmacological Reviews presents important review articles covering the broad spectrum of pharmacological research, including biochemical and cellular pharmacology, drug metabolism and disposition, renal pharmacology, neuropharmacology, behavioral pharmacology, clinical pharmacology, and toxicology. IUPHAR nomenclature reports are published in the journal.

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Impact Factor 17.3
Quartile Q1
Open Access Type Hybrid
ISSN 0031-6997
eISSN 1521-0081
Invitation Only No
Cost Range Open access APC: USD 4500 for full length articles; USD 3150 for short articles; ASPET members receive a 25% discount. Subscription publication has no open access publication fee.

Submission Instructions

Pharmacological Reviews accepts the following article types. Click on an article type to view submission instructions.

Reviews

Cover Letter A cover letter must be included with the proposal.
Abstract An abstract must be included with the proposal. Abstract must not exceed 250 words.
Manuscript Reviews are typically 30 or more printed pages, approximately 90 or more manuscript pages. The submission must include 3 to 6 keywords and a significance statement, and an AI declaration statement must be added before the references if AI tools were used in manuscript preparation.
References References must be cited in the text using superscript Arabic numerals and listed in numerical order of first appearance.
Figures & Tables Figures must be supplied as separate files, while table placement is not explicitly stated. Tables must be submitted as editable text with captions, and figures must have captions provided in a separate file.
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Iuphar Nomenclature Reports

Cover Letter A letter of submission must be included.
Abstract An abstract is required. Abstract must not exceed 250 words.
Manuscript Include 3 to 6 keywords, a significance statement of 1 to 2 sentences not exceeding 80 words immediately after the abstract, and an AI declaration section before the references if AI tools were used in manuscript preparation.
References References must be cited in the text using superscript Arabic numerals in order of appearance and listed numerically in the reference list with journal names abbreviated according to LTWA.
Figures & Tables Figures must be supplied as separate files with captions provided in a separate file, while tables must be submitted as editable text. Tables must be numbered consecutively, cited in the text, and include captions, and all images must be cited in the text, numbered in sequence, and accompanied by captions explaining symbols and abbreviations.
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Communications

Cover Letter A letter of submission must be included.
Abstract An abstract is required. Abstract must not exceed 250 words. Abstract must be unstructured.
Manuscript A significance statement of 1–2 sentences and no more than 80 words must appear immediately after the abstract. Keywords are optional, and if generative AI was used in manuscript preparation, a declaration section must be placed immediately before the references.
References References must be cited in the text using superscript Arabic numerals and listed in numerical order of appearance.
Figures & Tables Tables must be included as editable text, while figures must be supplied as separate files with captions provided in a separate file. Tables must be numbered consecutively and have captions, and all figures and tables must be cited in the text.
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Perspectives

Cover Letter A letter of submission must be included.
Abstract An abstract is required. Abstract must not exceed 250 words. Abstract must be unstructured.
Manuscript A significance statement of 1–2 sentences and no more than 80 words must appear immediately after the abstract. Keywords are optional, and if generative AI was used in manuscript preparation, a declaration section stating the tool used and the reason for using it must be placed immediately before the references.
References References must use numbered superscript citations in the text. References must be listed in the reference list in the order they appear in the text, with journal names abbreviated according to LTWA.
Figures & Tables Tables must be submitted as editable text, while figures and their captions must be uploaded as separate files. Tables must be numbered consecutively and include captions, and all figures and tables must be cited in the manuscript text.
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Recent Publications

Friend or Foe? Glial-Vascular Interactions in Health and Neurodegenerative Disease

Conor McQuaid, Michael Sewell, Axel Montagne

10.1016/j.pharmr.2026.100143
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Vein Graft Failure: Pathophysiology, Detection, Prevention and Emerging Therapeutic Strategies

Simon D. Brown, Sandra Sanchez-Esteban, Laura Clark, Katarina Miteva, Georgios Krilis, Rachael O. Forsythe, Stuart A. Nicklin, Samantha Carmichael, Colin Berry, Nawwar Al-Attar, David E. Newby, Andrew H. Baker

10.1016/j.pharmr.2026.100139
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International Union of Basic and Clinical Pharmacology xxx: Applying an objective evaluation to the status of Class A orphan G protein-coupled receptors

Stephen P.H. Alexander, Kirstie A. Bennett, Andrew J. Brown, Michelle Glass, David E. Gloriam, Julien Hanson, Paul A. Insel, Eamonn Kelly, Christopher J. Langmead, Kirill A. Martemyanov, Rick R. Neubig, Stefan Offermanns, Mette M. Rosenkilde, Gunnar Schulte, Nicola J. Smith, Huixian Wu, Elena Faccenda, Simon D. Harding, Anthony P. Davenport

10.1016/j.pharmr.2026.100141
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ARE WE UNDERESTIMATING THE BENEFITS OF LIPID-LOWERING THERAPIES?

Angela Pirillo, Manuela Casula, Elena Olmastroni, Stefano Scotti, Alberto Corsini, Alberico L. Catapano

10.1016/j.pharmr.2026.100140
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Reharnessing the therapeutic potential of gallium-based compounds in oncology: from the laboratory to the clinic

Christopher R. Chitambar, Casey J. Zoss, Mona M. Al-Gizawiy, Kathleen M. Schmainda, Jennifer M. Connelly

10.1016/j.pharmr.2026.100138
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Frequently asked questions

How long does it take to publish?

Is a cover letter required?

A proposal must include a cover letter, expanded outline, an abstract, a significance statement, and the corresponding author's curriculum vitae. A letter of submission is included in the submission checklist.

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What are the publication costs?

Open access APC is USD 4500 for full length articles and USD 3150 for short articles, excluding taxes. ASPET members receive a 25% discount. Subscription publication has no open access publication fee.

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Research Topics

Diverse Scientific and Economic Studies Human auditory perception and evaluation Educational Robotics and Engineering Receptor Mechanisms and Signaling Neuroscience and Neuropharmacology Research Ferroelectric and Negative Capacitance Devices Big Data and Digital Economy Neurotransmitter Receptor Influence on Behavior Neuropeptides and Animal Physiology Ion channel regulation and function Pharmacogenetics and Drug Metabolism Nicotinic Acetylcholine Receptors Study Drug Transport and Resistance Mechanisms Diet and metabolism studies Computational Drug Discovery Methods Pharmacological Receptor Mechanisms and Effects Estrogen and related hormone effects Hormonal Regulation and Hypertension Eicosanoids and Hypertension Pharmacology Adipose Tissue and Metabolism Pharmacological Effects and Toxicity Studies Cannabis and Cannabinoid Research Metabolism and Genetic Disorders Pain Mechanisms and Treatments Monoclonal and Polyclonal Antibodies Research