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Phytomedicine

Phytomedicine is the International Journal of Phytotherapy and Phytopharmacology, published in affiliation with the European Scientific Cooperative On Phytotherapy (ESCOP). It is a therapy-oriented journal focused on efficacy, safety, quality, mechanisms of action, and standardization of specified plant extracts, phytopharmaceuticals, and isolated constituents, including clinical, pharmacological, pharmacokinetic, and toxicological studies of herbal medicinal products and related compounds.

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Subject Integrative & Complementary Medicine, Pharmacology & Pharmacy
Impact Factor 8.3
Quartile Q1
Open Access Type Hybrid
ISSN 0944-7113
eISSN 1618-095X
Invitation Only No
Cost Range Open Access APC: USD 3,650 (excluding taxes); subscription publication: no publication fee charged to authors

Submission Instructions

Phytomedicine accepts the following article types. Click on an article type to view submission instructions.

Original Papers

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must include the headings Background, Purpose, Study Design, Methods, Results, and Conclusion.
Manuscript Original Papers should not exceed 5,000 words including references, tables, and figures. Include 1 to 7 keywords, 3 to 5 highlights submitted as a separate editable file, a graphical abstract submitted as a separate file, and a generative AI declaration in a new section before the references if AI was used in manuscript preparation.
References Original Papers should not exceed 30 references. References must use Harvard style. References must be arranged alphabetically without numbering, use abbreviated journal titles, and in-text citations for works with three or more authors must use the first author's last name followed by et al. and the year.
Figures & Tables Tables and figures must be uploaded as separate files and placed at the end of the manuscript rather than embedded in the text. Tables must be editable text with captions, and figures must be submitted separately with captions or legends provided on a separate page.
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Review Articles

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must include the headings Background, Purpose, Study Design, Methods, Results, and Conclusion.
Manuscript Herbal drug-monograph review articles are acceptable only if they include the newest pharmacological and toxicological issues and an outlook on future directions. The manuscript must include a generative AI declaration in a separate section placed before the references if AI was used in manuscript preparation, and 1 to 7 keywords are required.
References References must use Harvard style. References must be arranged alphabetically without numbering.
Figures & Tables Tables and figures must be uploaded as separate files and placed at the end of the manuscript rather than within the text. Tables must be editable text with captions, and figures must have separate legends on a separate page.
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Recent Publications

Piperine inhibits NLRP3 inflammasome activation and alleviates inflammatory disease

Rui Guo, Zhiqiang Niu, Feng Chen, Lingjun Zheng, Junyao Li, Luyao Qi, Guiping Wu, Xu Wang, Fei Xu, Jae Youl Cho, Weicheng Hu, Hongying Zhu, Fenglin Gu

10.1016/j.phymed.2026.158448
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EGCG inactivates tumor necrosis factor-alpha (TNFα) by inducing its higher-order assembly

Huanhuan Xu, Chenqiang Du, Ying Chen, Titi Liu, Shuxiao An, Zhe Jiang, Hao Chang, Chen Su, Qingrun Li, Hengrui Liang, Houchao Tao, Heng Ru, Tian Hua, Gaojie Song, Jun Sheng

10.1016/j.phymed.2026.158437
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Therapeutic effects of jaceosidin on atopic dermatitis via ubiquitin-mediated JAK1 degradation

Ruoqu Wei, Wenjie Cheng, Jie Zhang, Zou Quan, Yidong Tan, Zhen Zhang, Haoyu Wang

10.1016/j.phymed.2026.158446
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Structural insights into TRPA1 and TRPV1 modulation by flavonoid glycosides from licorice for cough relief

Yang Yi, Guifang Duan, Zonglin Dai, Xiaogang Zhou, Jian Huang, Zhengtong Jin, Ao Yang, Yue Li, Zhuo Huang, Min Ye

10.1016/j.phymed.2026.158419
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Molecular and bioinformatic mechanism of asiaticoside on macrophage-mediated keloid pathogenesis

Jia Huang, Yating Yang, Zhengxin Li, Wenbo Wang, Xiaoli Wu, Zhen Gao, Haifeng Chen, Wei Liu

10.1016/j.phymed.2026.158460
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Frequently asked questions

How long does it take to publish?

16 days from submission to first decision; 43 days from submission to decision after review; 125 days from submission to acceptance; 2 days from acceptance to first online publication.

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What are the publication costs?

Hybrid journal. Open access APC: USD 3,650 excluding taxes. Subscription publication: no publication fee charged to authors.

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Research Topics

Pharmacological Effects of Natural Compounds Natural product bioactivities and synthesis Traditional Chinese Medicine Analysis Ginseng Biological Effects and Applications Phytochemistry and Biological Activities Essential Oils and Antimicrobial Activity Toxin Mechanisms and Immunotoxins Genomics, phytochemicals, and oxidative stress Liver Disease Diagnosis and Treatment Gut microbiota and health Phytochemicals and Antioxidant Activities Drug-Induced Hepatotoxicity and Protection Inflammasome and immune disorders Natural Antidiabetic Agents Studies Neuroinflammation and Neurodegeneration Mechanisms Ferroptosis and cancer prognosis Autophagy in Disease and Therapy Tryptophan and brain disorders Medicinal Plants and Bioactive Compounds Bioactive Compounds and Antitumor Agents Metabolomics and Mass Spectrometry Studies Berberine and alkaloids research Neurological Disease Mechanisms and Treatments Bone Metabolism and Diseases Medicinal Plants and Neuroprotection

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