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Phytomedicine

Phytomedicine is the International Journal of Phytotherapy and Phytopharmacology, published in affiliation with the European Scientific Cooperative On Phytotherapy (ESCOP). It is a therapy-oriented journal focused on efficacy, safety, quality, mechanisms of action, and standardization of specified plant extracts, phytopharmaceuticals, and isolated constituents, including clinical, pharmacological, pharmacokinetic, and toxicological studies of herbal medicinal products and related compounds.

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Subject Integrative & Complementary Medicine, Pharmacology & Pharmacy
Impact Factor 8.3
Quartile Q1
Open Access Type Hybrid
ISSN 0944-7113
eISSN 1618-095X
Invitation Only No
Cost Range Open Access APC: USD 3,650 (excluding taxes); subscription publication: no publication fee charged to authors

Submission Instructions

Phytomedicine accepts the following article types. Click on an article type to view submission instructions.

Original Papers

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must include the headings Background, Purpose, Study Design, Methods, Results, and Conclusion.
Manuscript Original Papers should not exceed 5,000 words including references, tables, and figures. Include 1 to 7 keywords, 3 to 5 highlights submitted as a separate editable file, a graphical abstract submitted as a separate file, and a generative AI declaration in a new section before the references if AI was used in manuscript preparation.
References Original Papers should not exceed 30 references. References must use Harvard style. References must be arranged alphabetically without numbering, use abbreviated journal titles, and in-text citations for works with three or more authors must use the first author's last name followed by et al. and the year.
Figures & Tables Tables and figures must be uploaded as separate files and placed at the end of the manuscript rather than embedded in the text. Tables must be editable text with captions, and figures must be submitted separately with captions or legends provided on a separate page.
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Review Articles

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must include the headings Background, Purpose, Study Design, Methods, Results, and Conclusion.
Manuscript Herbal drug-monograph review articles are acceptable only if they include the newest pharmacological and toxicological issues and an outlook on future directions. The manuscript must include a generative AI declaration in a separate section placed before the references if AI was used in manuscript preparation, and 1 to 7 keywords are required.
References References must use Harvard style. References must be arranged alphabetically without numbering.
Figures & Tables Tables and figures must be uploaded as separate files and placed at the end of the manuscript rather than within the text. Tables must be editable text with captions, and figures must have separate legends on a separate page.
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Recent Publications

The Kunduan Yimu Decoction improves rheumatoid arthritis by targeting microRNA-155-5p to enhance autophagy and reduce inflammation

Xiao-Bao Liu, Fang-Shu Zou, Mei-Feng Shi, Xiao-Na Ma, Qing-Ping Liu, Chang-Song Lin, Wei Gao, Min-Ying Liu, Qiang Xu

10.1016/j.phymed.2026.158252
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Tongguanteng injection induces cell cycle arrest and drives ferroptosis through AURKA/KEAP1/NRF2 axis in breast cancer

Hanlu Liang, Qixuan Ding, Jiayi Chen, Shuai Zhao, Yangyun Zhou, Yujie Hu, Lingyan Xu, Meizhi Shi, Jiao Yang, Xiangqi Zhang, Jingxian Zhang, Cheng Guo, Yonglong Han, Junjun Chen

10.1016/j.phymed.2026.158250
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Schisandrin B Alleviates APAP-Induced Hepatocyte Ferroptosis via the GPX4 Axis: Insights from Human iPSC-Derived Hepatic Organoids and Rat Models

Zhuqian Tang, Xiaohong Yang, Mingyue Zhang, Bin Yang, Hua Li

10.1016/j.phymed.2026.158241
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Haizao Yuhu Decoction alleviates goiter via the gut-thyroid axis: microbiota-derived SCFAs promote hormone synthesis and restore apoptosis

Wenyong Liao, Jie Gao, Jiwen Zhang, Yinghao Wu, Yang Jiang, Haiyan Liu, Shaohong Chen, Linlin Xiu, Gansheng Zhong

10.1016/j.phymed.2026.158256
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Ergothioneine alleviates hepatic steatosis by modulating PCYT2 to restore the phosphatidylethanolamine-ACOT8 homeostasis

Rongyi Ye, Yihan Wang, Kebo Wang, Nan Huang, Guo Liu, Dexin Gao, Xinru Li, Mengxue Yang, Jing Wang, Chen Chen

10.1016/j.phymed.2026.158238
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Frequently asked questions

How long does it take to publish?

16 days from submission to first decision; 43 days from submission to decision after review; 125 days from submission to acceptance; 2 days from acceptance to first online publication.

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What are the publication costs?

Hybrid journal. Open access APC: USD 3,650 excluding taxes. Subscription publication: no publication fee charged to authors.

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Research Topics

Pharmacological Effects of Natural Compounds Natural product bioactivities and synthesis Traditional Chinese Medicine Analysis Ginseng Biological Effects and Applications Phytochemistry and Biological Activities Essential Oils and Antimicrobial Activity Toxin Mechanisms and Immunotoxins Genomics, phytochemicals, and oxidative stress Liver Disease Diagnosis and Treatment Gut microbiota and health Phytochemicals and Antioxidant Activities Drug-Induced Hepatotoxicity and Protection Inflammasome and immune disorders Natural Antidiabetic Agents Studies Neuroinflammation and Neurodegeneration Mechanisms Ferroptosis and cancer prognosis Autophagy in Disease and Therapy Tryptophan and brain disorders Medicinal Plants and Bioactive Compounds Bioactive Compounds and Antitumor Agents Metabolomics and Mass Spectrometry Studies Berberine and alkaloids research Neurological Disease Mechanisms and Treatments Bone Metabolism and Diseases Medicinal Plants and Neuroprotection

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