JC

JACC CardioOncology

JACC: CardioOncology is an open access specialist journal in the JACC family that advances cardiovascular care of cancer patients through innovative science and evidence-based knowledge. It publishes pre-clinical, translational, and clinical research, as well as best practices in cardio-oncology, covering areas such as disease mechanisms, model systems, therapeutics, epidemiology, precision medicine, prevention, amyloidosis, cardiovascular risk factors, heart failure, and vascular disease.

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Subject Cardiac & Cardiovascular Systems, Oncology
Impact Factor 12.8
Quartile Q1
Open Access Type Open
ISSN 2666-0873
eISSN 2666-0873
Invitation Only No
Cost Range Article Publishing Charge: USD 4410 for full length articles and USD 1764 for short communications, excluding taxes.

Submission Instructions

JACC CardioOncology accepts the following article types. Click on an article type to view submission instructions.

Original Investigations

Cover Letter Cover letter is required and must state that the paper is not under consideration elsewhere, that none of its contents have been previously published, that all authors have read and approved the manuscript, and disclose any potential conflicts of interest or explicitly state none. Cover letter must include the contribution of each author, specify the corresponding author, denote ethical approval, and may request expedited review with a rationale.
Abstract Abstract is required. Abstract must be structured and must not exceed 250 words. Abstract must be structured. Abstract must use the headings Background, Objectives, Methods, Results, and Conclusions.
Manuscript Manuscript must not exceed 5,000 words including text from the introduction through the conclusion, references, and figure legends. Text must be structured as Introduction, Methods, Results, Discussion, and Conclusions, and must include a study limitations section at the end of the Discussion. Manuscript must include Clinical Perspectives after the text and before the references, a Central Illustration with a title and 50 to 100 word legend, up to 6 keywords after the abstract, and a separate abbreviations list of up to 10 items following the abstract.
References References must be numbered consecutively in order of first mention and cited in the text with numerals in parentheses, listing all authors if 6 or fewer or the first 3 followed by et al if more than 6.
Figures & Tables There is no figure or table limit, and a Central Illustration is required. Figures and tables should be cited in numerical order in the text, with the Central Illustration legend listed first among figure legends unless it is an existing figure. Central Illustration must have a title of no more than 10 words and a combined title-and-caption legend of 50 to 100 words.
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State-Of-The-Art Reviews

Cover Letter Cover letter is required. Cover letter must state that the paper is not under consideration elsewhere, that its contents have not been previously published, that all authors have read and approved the manuscript, disclose any conflicts of interest or their absence, specify the corresponding author, delineate each author's contribution, and explain how the submission differs from existing reviews on the subject.
Abstract An abstract is required. Abstract must be unstructured and no more than 150 words. Abstract must be unstructured.
Manuscript Manuscript must not exceed 10,000 words including text from the introduction to conclusion, references, and figure legends. Manuscript text should be structured as Introduction, Methods, Results, Discussion, and Conclusions. Manuscript must include a Central Illustration and either Highlights or a Main Message, with 3 to 4 highlight bullets of no more than 15 words each that cover context or background, the main message and recommendations, and future directions.
References References must be cited in numerical order, listed consecutively by order of mention, use numerals in parentheses in the text, list all authors if 6 or fewer or the first 3 followed by et al if more than 6, use Index Medicus journal abbreviations, and avoid personal communications, unpublished data, and abstracts older than 2 years.
Figures & Tables There is no figure limit and no table limit, but a Central Illustration is required. The entire manuscript including tables should be uploaded as a Microsoft Word document. Central Illustration must include a title of no more than 10 words and a combined title and caption legend of 50 to 100 words, and its legend should appear first in the figure legends unless it is an existing figure.
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Primers In Cardio-Oncology

Cover Letter A cover letter is required, and for long-form manuscripts it should explain how the submission differs from existing publications on the topic. The cover letter must state that the paper is not under consideration elsewhere, that its contents have not been previously published, that all authors have read and approved the manuscript, disclose any potential conflicts of interest or state none, identify the corresponding author, and delineate each author's contribution.
Abstract Short-form manuscripts do not require an abstract, whereas long-form manuscripts must include an abstract. For long-form manuscripts, the abstract must be no more than 150 words. For long-form manuscripts, the abstract must be unstructured.
Manuscript Short-form manuscripts must not exceed 2,000 words and long-form manuscripts must not exceed 10,000 words, in both cases including text from the introduction to conclusion, references, and figure legends. Short-form manuscripts must not use subheadings within the text. Primers In Cardio-Oncology require Highlights or Main Messages consisting of 3 to 4 brief bullets of no more than 15 words each, and long-form manuscripts must also include a Central Illustration while Clinical Perspectives are not required.
References Short-form manuscripts may include no more than 10 references. References must be cited numerically in order of mention in the text, with all authors listed if 6 or fewer and otherwise the first 3 followed by et al.
Figures & Tables Short-form manuscripts may include no more than 2 single-paneled figures or 1 simple table and 1 single-paneled figure, while long-form manuscripts have no figure or table limit. Supplemental material is not permitted for this article type. For long-form manuscripts, the Central Illustration is required and must have a title of no more than 10 words plus a total legend of 50 to 100 words, listed first among figure legends unless it is an existing figure.
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Long Form

Cover Letter A cover letter is required. Cover letter must state that the paper is not under consideration elsewhere, has not been previously published, has been read and approved by all authors, disclose any potential conflicts of interest or state none, identify the corresponding author, delineate each author's contribution, and explain how the submission differs from existing publications on the topic.
Abstract An abstract is required. Abstract must be unstructured and no more than 150 words. Abstract must be unstructured. No mandatory abstract headings are specified.
Manuscript Manuscript must not exceed 10,000 words including text from the introduction to conclusion, references, and figure legends. Text should be structured as Introduction, Methods, Results, Discussion, and Conclusions. Manuscript must include Highlights or Main Messages, a Central Illustration, up to 6 keywords immediately after the abstract, and a separate abbreviations page listing up to 10 abbreviations or acronyms after the abstract.
References References must be cited in numerical order by order of mention, listed consecutively, use numerals in parentheses in the text, list all authors if 6 or fewer or the first 3 followed by et al if more than 6, use Index Medicus journal abbreviations, and not include personal communications, unpublished data, or abstracts older than 2 years.
Figures & Tables There is no figure limit and no table limit. The entire manuscript including tables should be uploaded as a Microsoft Word document. A Central Illustration is required and must have a title of no more than 10 words plus a legend of 50 to 100 words listed first among the figure legends unless it is an existing figure.
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Research Letters

Cover Letter A cover letter is required. Cover letter must state that the paper is not under consideration elsewhere, has not been previously published, has been read and approved by all authors, names the corresponding author, discloses any conflicts of interest or states none, includes each author's contribution, and denotes ethical approval.
Abstract Abstract is not required.
Manuscript Manuscript must not exceed 1,000 words including text from the introduction through the conclusion, references, and figure legends. Text should be organized from introduction to conclusion without subheadings. Supplemental material is not permitted, and for studies involving humans or animals the article body must state the required approval or compliance information, including animal-handling protocol when applicable.
References References are limited to no more than 5. References must be cited in the text by numerals in parentheses in numerical order, listed consecutively by order of mention, list all authors if 6 or fewer or the first 3 followed by et al if more than 6, use Index Medicus journal abbreviations, and exclude personal communications, unpublished data, and abstracts older than 2 years.
Figures & Tables Submission may include no more than 1 simple figure with up to 2 parts or 1 simple table.
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Clinical Case Challenge

Cover Letter A cover letter is required. Cover letter must state that the paper is not under consideration elsewhere, that none of its contents have been previously published, that all authors have read and approved the manuscript, disclose any potential conflict of interest or state none exists, identify the corresponding author, and delineate each author's contribution.
Abstract Abstract is not required.
Manuscript Manuscript must not exceed 2,000 words including text from the introduction to conclusion, references, and figure legends. Text must not use subheadings. Clinical Perspectives and a Central Illustration are not required.
References References are limited to 10. References must be cited in numerical order, numbered consecutively by order of mention, identified in the text by numerals in parentheses, list all authors if 6 or fewer or the first 3 followed by et al if 7 or more, use Index Medicus journal abbreviations, and omit periods after authors' initials.
Figures & Tables Submissions may include no more than 2 single-paneled figures or 1 simple table and 1 single-paneled figure. Videos or supplemental material are not permitted.
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Letters To The Editor

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Manuscript must not exceed 500 words including references and a figure legend if applicable. Manuscript must include a title page and a unique title of 15 words or less that does not include the title of the original investigation.
References References are limited to no more than 5. The cited article must be listed as the first reference.
Figures & Tables Submission may include no more than 1 simple figure in no more than 2 parts or 1 simple table.
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Recent Publications

Sacubitril/Valsartan in Anthracycline-Treated Patients

Luigi Spadafora, Massimiliano Camilli

10.1016/j.jaccao.2026.04.001
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Rechallenge After Immune Checkpoint Inhibitors Myocarditis: Evidence and a Practical Framework

Joe-Elie Salem, Stephane Ederhy, Meiying Zhang, Marie Bretagne

10.1016/j.jaccao.2026.05.009
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The Future of Bleeding Risk Assessment in Cancer-Associated Thrombosis

Larissa Araújo de Lucena, Juliana Giorgi, Caroline Fischer-Bacca

10.1016/j.jaccao.2026.05.006
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António Araújo, José Costa, Ana Rodrigues

10.1016/j.jaccao.2026.05.007
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The Promise and Pitfalls of TTR Stabilization Assays in ATTR-CM

Ronald M. Witteles

10.1016/j.jaccao.2026.04.002
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Frequently asked questions

How long does it take to publish?

For expedited review, the journal commits to a decision on suitability for expedited publication processing within 2 days and an initial decision within 14 days.

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Is a cover letter required?

A cover letter is required at submission. It must state that the paper is not under consideration elsewhere, that none of the contents have been previously published, that all authors have read and approved the manuscript, and disclose any potential conflict of interest or state that none exists. The corresponding author should be specified. Ethical approval should be noted in the cover letter. For revisions or appeals, a rebuttal letter is required. A short paragraph explaining why the paper merits publication may be included, and authors may suggest potential reviewers or reviewers to avoid. Authors requesting expedited review should include the request and rationale in the cover letter.

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What are the publication costs?

Article Publishing Charge: USD 4410 for full length articles and USD 1764 for short communications, excluding taxes.

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Research Topics

Chemotherapy-induced cardiotoxicity and mitigation Cardiac Imaging and Diagnostics Amyloidosis: Diagnosis, Treatment, Outcomes Cancer Treatment and Pharmacology Cardiovascular Function and Risk Factors Cardiac tumors and thrombi Cancer Immunotherapy and Biomarkers Childhood Cancer Survivors' Quality of Life Venous Thromboembolism Diagnosis and Management Parathyroid Disorders and Treatments Cancer-related cognitive impairment studies Diverse Scientific and Economic Studies Human auditory perception and evaluation Cancer survivorship and care Acute Myocardial Infarction Research Heart Failure Treatment and Management Educational Robotics and Engineering CAR-T cell therapy research Atrial Fibrillation Management and Outcomes Cardiac Ischemia and Reperfusion Lung Cancer Research Studies Cancer, Lipids, and Metabolism Cardiac Health and Mental Health Chronic Myeloid Leukemia Treatments Cardiac Structural Anomalies and Repair

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