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Liver International

Liver International is a multi-disciplinary hepatology journal promoting all aspects of the field from basic research to applied clinical studies, and is an essential resource for everyone working on normal and abnormal structure and function in the liver and its constituent cells, including clinicians and basic scientists.

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Impact Factor 5.2
Quartile Q1
Open Access Type Hybrid
ISSN 1478-3223
eISSN 1478-3231
Invitation Only No
Cost Range Open access publication is available for a fee. Any article except fully open access articles that exceeds 9 published pages will be charged GBP 100 per page.

Submission Instructions

Liver International accepts the following article types. Click on an article type to view submission instructions.

Original Articles

Cover Letter A cover letter must be uploaded with the manuscript. The cover letter must disclose all commercial relationships that might pose a conflict of interest, including detailed information if a possible conflict exists.
Abstract A structured abstract is required for Original Articles. The abstract must not exceed 250 words. The abstract must be structured. The abstract must use the headings Background & Aims, Methods, Results, and Conclusions.
Manuscript Original Articles must not exceed 5,000 words including the title page, abstract, lay summary, and main text, but excluding references, figures, and tables including legends. The manuscript must contain the sections abstract, introduction, methods, results, and conclusions. The main text file must include 3-6 keywords and a lay summary, and Original Articles require a lay summary of two or three sentences in plain English for a non-medical audience at revised submission.
References Original Articles must include no more than 50 references. References must be numbered consecutively in order of appearance and cited in the text using Arabic superscript numerals, and references with more than 6 authors must list the first 3 followed by et al.
Figures & Tables Original Articles must include no more than 8 figures and/or tables, with up to 6 individual panels each. Figures must be supplied as separate files and must not be embedded in the main body text, while the manuscript may otherwise be submitted as a single file including text, figures, and tables or as separate files. Figures and tables must have legends, and figure legends must be listed at the end of the manuscript.
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Systematic Reviews

Cover Letter A cover letter must be uploaded with the manuscript. The cover letter must disclose all commercial relationships that might pose a conflict of interest, including detailed information if conflicts exist.
Abstract A structured abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must use the headings Background & Aims, Methods, Results, and Conclusions.
Manuscript Manuscript must not exceed 6,000 words including the title page, abstract, key points, and main text, with references, figures, and tables excluded from the count. Manuscript must include the sections abstract, introduction, methods, results, and conclusions. Manuscript must include key points in a box not exceeding 100 words in total and include 3-6 keywords.
References Manuscript must include no more than 50 references. References must be numbered consecutively in order of appearance and cited in the text using Arabic superscript numerals, with more than six authors shortened to the first three followed by et al.
Figures & Tables Manuscript may include up to 4 figures and/or tables. Figures must be supplied as separate files and must not be embedded in the main body text, while the manuscript may otherwise be submitted as a single file including text, figures, and tables or as separate files. Figures and tables must have legends.
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Meta-Analysis

Cover Letter A cover letter must be uploaded with the manuscript. The cover letter must disclose all commercial relationships that might pose a conflict of interest, including detailed financial and entity information if applicable.
Abstract A structured abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must use the headings Background & Aims, Methods, Results, and Conclusions.
Manuscript Manuscript must not exceed 6,000 words including the title page, abstract, key points, and main text, with references, figures, and tables excluded from the count. Manuscript must be submitted as an Original Article and include the sections abstract, introduction, methods, results, and conclusions. Manuscript must include key points in a box with a total length of no more than 100 words.
References Manuscript must include no more than 50 references. References must be numbered consecutively in order of appearance, cited in the text with Arabic superscript numerals, and list the first three authors followed by et al. when there are more than six authors.
Figures & Tables Manuscript may include up to 4 figures and/or tables. Figures may be submitted within a single manuscript file or as separate files at submission, but figures must not be embedded in the main body text and supporting information must be supplied separately. Figures and tables must have legends.
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Review Articles

Cover Letter A cover letter must be uploaded with the manuscript. The cover letter must disclose any commercial relationships that could pose a conflict of interest, including detailed identifying and financial information if a conflict exists.
Abstract An abstract is required for Review Articles. The abstract must be unstructured and no more than 250 words. The abstract must be unstructured.
Manuscript Review Articles have a recommended length of 5,000 words and a maximum of 6,000 words including the title page, abstract, key points, and main text, excluding references, figures, and tables with legends. The manuscript must include the required sections, including abstract, introduction, methods, results, and conclusions. The manuscript must include key points in a boxed format with no more than 5 bullet points and no more than 100 words in total, and it must also include 3-6 keywords.
References Review Articles should not exceed 150 references. References must be numbered consecutively in order of appearance, cited in the text with Arabic superscript numerals, and if a reference has more than 6 authors only the first 3 should be listed followed by et al.
Figures & Tables Figures must be supplied as separate files and must not be embedded in the main body text, while the manuscript file must include tables and figure legends. Figures and tables must have legends.
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Brief Definitive Reports

Cover Letter A cover letter must be uploaded with the submission. The cover letter must disclose any commercial relationships that could pose a conflict of interest, including detailed conflict information when applicable.
Abstract An abstract is required. The abstract must be unstructured and no more than 150 words. The abstract must be unstructured.
Manuscript The manuscript must not exceed 3,000 words including the title page, abstract, main text, and references, with figures and tables including legends excluded from the word count. The manuscript must contain abstract, introduction, methods, results, and conclusions sections. The manuscript must include 3-6 keywords and a lay summary or key points.
References The submission must include no more than 20 references. References must be numbered consecutively in order of appearance and cited in the text using Arabic superscript numerals, and references with more than six authors must list the first three followed by et al.
Figures & Tables The submission must include no more than 2 figures or tables. Figures must be supplied as separate files and must not be embedded in the main body text, while the manuscript file must include tables and figure legends. Figures and tables must have legends.
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Mini-Reviews

Cover Letter A cover letter must be uploaded with the manuscript. The cover letter must disclose all commercial relationships that might pose a conflict of interest, including detailed conflict information when applicable.
Abstract Mini-Reviews must include an abstract. The abstract must be unstructured and no more than 250 words. The abstract must be unstructured.
Manuscript Mini-Reviews must not exceed 4,000 words including the title page, unstructured abstract, key points, and main text, but excluding references, figure legends, and tables. The manuscript must include the required sections, including abstract, introduction, methods, results, and conclusions. The manuscript must include 3-6 keywords and a boxed key points section with no more than 5 bullet points and no more than 100 words in total.
References Mini-Reviews must include no more than 30 references. References must be numbered consecutively in order of appearance with Arabic superscript numerals in the text, and references with more than 6 authors must list the first 3 followed by et al.
Figures & Tables Mini-Reviews must include no more than 2 figures or tables. Figures must be supplied as separate files and must not be embedded in the main body text, while the manuscript may be submitted as a single file including tables. Figures and tables must have legends, and tables in the manuscript must be complete with title and footnotes.
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Research Letters

Cover Letter A cover letter must be uploaded with the submission. The cover letter must disclose all commercial relationships that might pose a conflict of interest, including detailed financial and entity information if applicable.
Abstract An abstract is not required.
Manuscript Research Letters must not exceed 1,500 words. Research Letters must address a recently published paper from the last six months on an urgent or hot topic. The manuscript must include 3–6 keywords and a lay summary or key points.
References Research Letters must include no more than 10 references. References must be numbered consecutively in order of appearance and cited in the text using Arabic superscript numerals, with the first three authors listed followed by et al. when there are more than six authors.
Figures & Tables Research Letters must include no more than 2 figures or tables. The manuscript may be submitted as a single file including figures and tables or as separate files, but figures must not be embedded in the main body text and must be supplied as separate files. Figures and tables must have legends, and figure legends must be listed at the end of the manuscript.
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Letters To The Editor

Cover Letter A cover letter must be uploaded with the submission. The cover letter must disclose commercial relationships that could pose a conflict of interest, including detailed information if conflicts exist.
Abstract Abstract requirements are not specified.
Manuscript Main text must not exceed 400 words. A title page must be provided.
References No more than 5 references are permitted. The paper being commented upon must be listed as the first reference.
Figures & Tables No more than 1 figure or table may be included.
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Recent Publications

Post‐ TIPS Dynamics of von Willebrand Factor for Risk Stratification After TIPS Placement

Marlene Hintersteininger, Simon Johannes Gairing, Katrin Kirsch, Theresa Müllner‐Bucsics, Susanna Riegler, Lukas Reider, Mathias Jachs, Lorenz Balcar, Eva M. Schleicher, Jasmin Söhngen, Lukas Müller, Michael B. Pitton, Julia Weinmann‐Menke, Christian M. Lange, Peter R. Galle, Michael Trauner, Mattias Mandorfer, Thomas Reiberger, Christian Labenz, Lukas Hartl

10.1111/liv.70736
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Acute HEV Infection Is a Relevant Cause of Decompensation and ACLF in Patients With Liver Cirrhosis

Katja Dinkelborg, Christian Niehaus, Birgit Bremer, Christine Wundes, Anja Tiede, Natalie Petruch, Katja Deterding, Anke R. M. Kraft, Björn Hartleben, Markus Cornberg, Heiner Wedemeyer, Patrick Behrendt, Benjamin Maasoumy

10.1111/liv.70727
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Reply to: ‘Bile VEGF in Malignant Biliary Stenosis: Promising Signal or Clinical Discriminator?’

Lucien Grados, Ganesh D. Sockalingum, Gerard Thiefin, Elia Gigante

10.1111/liv.70740
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Direct Acting Antivirals Before Surgical Resection of HCV Related HCC : Impact on Tumour Pathology and Outcomes

Giuseppina Brancaccio, Alessandro Vitale, Francesco Paolo Russo, Giuseppe Cabibbo, Salvatore Gruttadauria, Duilio Pagano, Giovanni Battista Levi Sandri, Valerio Giannelli, Matteo Cescon, Carlo Sposito, Daniele Nicolini, Leonardo Centonze, Stefano Di Sandro, Davide Ghinolfi, Giovanni Di Costanzo, Raffaella Tortora, Luca Viganò, Fabrizio Romano, Mattia Garancini, Maria Rendina, Francesca Romana Ponziani, Felice Giuliante, Tommaso Manzia, Umberto Baccarani, Riccardo Pravisani, Fabio Melandro, Quirino Lai, Massimo A. Iavarone, Filomena Morisco, Francesco D'Amico, Edoardo Giannini, Giovanni Battista Gaeta, Umberto Cillo

10.1111/liv.70738
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Validation of Risk Models for Predicting Post‐SVR HCC in Real‐World Surveillance Across Global Geographic Regions

Hidenori Toyoda, Yujin Hoshida, Neehar D. Parikh, Prasun K. Jalal, Federico Piñero, Manuel Mendizabal, Ezequiel Ridruejo, Hugo Cheinquer, Andrea Casadei‐Gardini, Mounika Kanneganti, Arndt Weinmann, Markus Peck‐Radosavljevic, Jean‐Francois Dufour, Pompilia Radu, Gamal Shiha, Riham Soliman, Shiv K. Sarin, Manoj Kumar, Jing‐Houng Wang, Pisit Tangkijvanich, Wattana Sukeepaisarnjaroen, Masanori Atsukawa, Haruki Uojima, Akito Nozaki, Makoto Nakamuta, Koichi Takaguchi, Atsushi Hiraoka, Hiroshi Abe, Kentaro Matsuura, Tsunamasa Watanabe, Noritomo Shimada, Kunihiko Tsuji, Toru Ishikawa, Shigeru Mikami, Ei Itobayashi, Philip J. Johnson, Amit G. Singal

10.1111/liv.70734
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Frequently asked questions

How long does it take to publish?

Submission to first decision: 4 days (median).

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Is a cover letter required?

A cover letter must be uploaded with all manuscripts. It may outline the strengths of the manuscript and must disclose all commercial relationships and any conflicts of interest, including detailed conflict information when applicable.

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What are the publication costs?

Subscription journal with an open access option.

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Research Topics

Liver Disease Diagnosis and Treatment Liver Disease and Transplantation Hepatitis C virus research Hepatitis B Virus Studies Hepatocellular Carcinoma Treatment and Prognosis Liver Diseases and Immunity Organ Transplantation Techniques and Outcomes Liver physiology and pathology Drug-Induced Hepatotoxicity and Protection Alcohol Consumption and Health Effects Diet, Metabolism, and Disease Hepatitis Viruses Studies and Epidemiology Cholangiocarcinoma and Gallbladder Cancer Studies Pediatric Hepatobiliary Diseases and Treatments Drug Transport and Resistance Mechanisms Gallbladder and Bile Duct Disorders Pancreatitis Pathology and Treatment Diverse Scientific and Economic Studies Human auditory perception and evaluation Educational Robotics and Engineering Endoplasmic Reticulum Stress and Disease Systemic Lupus Erythematosus Research HIV/AIDS drug development and treatment Cancer, Lipids, and Metabolism Pancreatic and Hepatic Oncology Research