Overview
Submission Instructions
Recent Publications
Frequently Asked Questions
Research Topics
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Nature Cardiovascular Research publishes cardiovascular research and related content including Articles, Review Articles, Perspectives, Technical Reports, Research Highlights, News & Views, Comments and Research Briefings. The journal is open for submissions of original research articles and Reviews/Perspectives.
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Subject
Cardiac & Cardiovascular Systems
Impact Factor
10.8
Quartile
Q1
Open Access Type
Hybrid
eISSN
2731-0590
Invitation Only
No
Cost Range
Article Processing Charge applies for gold open access publication.
Submission Instructions
Nature Cardiovascular Research accepts the following article types. Click on an article type to view submission instructions.
Article
Cover Letter
A cover letter must be included with the submission. Cover letter should explain the importance of the work and its suitability for the journal’s diverse readership, and if double-blind peer review is chosen it must include all authors’ affiliations and contact information.
Abstract
An abstract is required. Abstract must be up to 150 words. Abstract must be unstructured and unreferenced. Abstract should briefly describe the background and rationale and then state the main conclusions introduced by the phrase 'Here we show' or an equivalent.
Manuscript
Main text must be up to 4,500 words excluding the abstract, Methods, references and figure legends. Manuscript should be divided into Introduction without a heading, Results, Discussion and Online Methods, with topical subheadings in Results and Online Methods only and none in Discussion. Manuscript file must include Methods, figures and Extended Data if applicable, and any use of a Large Language Model must be documented in the Methods section or a suitable alternative section if no Methods section is available.
References
References are typically recommended up to 60. References must be numerical. References must be numbered sequentially and cited articles must include article titles, with Methods-only references continuing the numbering from the main text.
Figures & Tables
Display items are limited to 8 figures and/or tables, with up to 10 additional Extended Data display items allowed. Tables must be included at the end of the text document. All figures must be cited in sequence within the main text.
Analysis
Cover Letter
A cover letter is required. Cover letter should explain the importance of the work, why it suits the journal’s broad readership, and state whether there have been prior discussions with an editor about the work.
Abstract
An abstract is required. Abstract must be 100–150 words. Abstract must be unstructured. Abstract must briefly present the background and rationale followed by the main conclusions introduced by the phrase 'Here we show' or an equivalent.
Manuscript
Main text must be up to 4,000 words excluding the abstract, online Methods, references and figure legends. Manuscript must be organized as Introduction without a heading, Results, Discussion and Online Methods, with subheadings allowed in Results and Online Methods but not in Discussion. Methods must contain enough detail for interpretation and replication, use of a Large Language Model must be documented in Methods or a suitable alternative section, and Supplementary Information may be included.
References
References are typically recommended up to 50. References must be numerical. References must be numbered sequentially in the order they appear, with Methods-only references continuing from the end of the main text reference list.
Figures & Tables
Manuscript may include up to 6 display items and up to 10 Extended Data display items. Tables must be included at the end of the text document. All figures must be cited in sequence in the main text.
Letter
Cover Letter
A cover letter must be included with the submission. Cover letter should explain the importance of the work, why it suits the journal’s broad readership, and if double-blind peer review is chosen, include all authors’ affiliations and contact information.
Abstract
An abstract is not permitted because a Letter must include an introductory paragraph instead. The introductory paragraph must be no longer than 150 words. The summary must be provided as an unstructured introductory paragraph that is referenced and counted as part of the main text. The introductory paragraph must summarize the background, rationale, main results and implications, and should introduce the main conclusions with 'Here we show' or equivalent.
Manuscript
Main text must not exceed 2,500 words, excluding the introductory paragraph, online Methods, references and figure legends. Letters must not be divided by headings, except that the online Methods may use up to two levels of headings. Use of a Large Language Model must be documented in the Methods section or another suitable section if no Methods section is available.
References
References are typically recommended up to 40. References must be numbered sequentially and cited article references must include article titles.
Figures & Tables
Letters must include 2–4 display items and may include up to 10 Extended Data display items. Tables must be included at the end of the text document, while complex tables may be submitted as a separate Excel file.
Resource
Cover Letter
A cover letter is required. Cover letter should explain the importance of the work, why it suits the journal’s diverse readership, and whether there have been prior discussions with an editor.
Abstract
An abstract is required. Abstract must be up to 150 words. Abstract must be unstructured and unreferenced. Abstract must briefly state the background and rationale and then the main conclusions introduced by the phrase 'Here we show' or an equivalent.
Manuscript
Main text must be up to 4,500 words, excluding the abstract, Online Methods, references and figure legends. Manuscript must be divided into Introduction without a heading, Results, Discussion and Online Methods, with Results and Online Methods divided by topical subheadings and no subheadings in the Discussion. Manuscript file must include Methods, figures and Extended Data if applicable, a reference list, and documentation of any Large Language Model use in the Methods section or a suitable alternative section.
References
References are typically recommended up to 60. References must be numbered sequentially in the order of Main Text, Methods, Data Availability Section, Tables, Figure Legends, Box and Extended Data Figures, with only one publication given for each reference.
Figures & Tables
Display items are limited to 8 figures and/or tables, and up to 10 Extended Data display items are allowed. Tables must be included at the end of the text document.
Technical Report
Cover Letter
A cover letter must be included with the submission. The cover letter should explain the importance of the work and why it is appropriate for the diverse readership of Nature Cardiovascular Research.
Abstract
An abstract is required. The abstract should be unstructured as a brief account of the background and rationale followed by a statement of the main conclusions introduced by 'Here we show' or an equivalent phrase.
Manuscript
The manuscript must include separate sections for Introduction, Results, Discussion and Methods. Use of a Large Language Model must be documented in the Methods section or in a suitable alternative section if no Methods section is available.
References
References are typically recommended up to 60. References must be numerical. References must be numbered sequentially in the order of Main Text, Methods, Data Availability Section, Tables, Figure Legends, Box and Extended Data Figures, with only one publication given for each reference.
Figures & Tables
Up to 10 Extended Data display items, including figures and/or tables, are allowed. Tables must be included at the end of the text document.
Review
Cover Letter
A cover letter is required with the submission. The cover letter should explain the importance of the work, why it suits a diverse readership, disclose related manuscripts and prior editorial discussions, and include all authors’ affiliations and contact information if double-blind peer review is chosen.
Abstract
An abstract is required and must be unreferenced. Abstract must be no more than 150 words. Abstract must be unstructured.
Manuscript
Main text must be 4,000–6,000 words. The article should not include original unpublished research findings except minimal new supporting data, and up to three subheading levels are allowed. Use of a Large Language Model must be documented in the Methods section or another suitable section if no Methods section is available.
References
References must not exceed 150. References and in-text citations must use numerical citation style. Citations should be selective, references for cited articles must include article titles, and brief annotations for particularly important studies comprising no more than 10% of references are encouraged.
Figures & Tables
Display items, including figures, tables and boxes, must total 4–8. Tables must be included at the end of the text document.
Recent Publications
Tolerogenic DCs expressing anti-FAP chimeric antigen receptor prevent adverse cardiac remodeling
Elisa Martini
10.1038/s44161-026-00823-5
View Publication
High-resolution cardiac mapping meets computational imaging to merge structure and function
Bastiaan J. Boukens, Daniël A. Pijnappels
10.1038/s44161-026-00812-8
View Publication
The NPR1 inhibitor XXB750 may worsen heart failure
Andrea Tavosanis
10.1038/s44161-026-00820-8
View Publication
CAMK2D causes heart failure in mice with RBM20 cardiomyopathy
Maarten M. G. van den Hoogenhof, Javier Duran, Thiago Britto-Borges, Vasco Sequeira, Elena Kemmling, Laura Konrad, Friederike Schreiter, David C. Lennermann, Joshua Hartmann, Laura Schraft, Julia Kornienko, Theresa Bock, Marcus Krüger, Christoph Maack, Christoph Dieterich, Lars M. Steinmetz, Matthias Dewenter, Johannes Backs
10.1038/s44161-026-00818-2
View Publication
Antibody–siRNA conjugates enable macrophage-specific osteopontin inhibition to suppress atrial fibrillation
Na Li
10.1038/s44161-026-00808-4
View Publication
Frequently asked questions
How long does it take to publish?
Median submission to first editorial decision is 5 days. Median submission to acceptance is 232 days.
Reformat to Nature Cardiovascular Research using Livewrite PremiumIs a cover letter required?
A cover letter is required for revised manuscripts when additional information is requested by the editors.
Reformat to Nature Cardiovascular Research using Livewrite PremiumWhat are the publication costs?
Article Processing Charge applies for gold open access publication.
Reformat to Nature Cardiovascular Research using Livewrite PremiumResearch Topics
Congenital heart defects research
Cardiac Fibrosis and Remodeling
Atherosclerosis and Cardiovascular Diseases
Cardiac electrophysiology and arrhythmias
Cardiovascular Function and Risk Factors
Cardiomyopathy and Myosin Studies
Single-cell and spatial transcriptomics
RNA modifications and cancer
Tissue Engineering and Regenerative Medicine
Viral Infections and Immunology Research
Immune cells in cancer
Ion channel regulation and function
RNA Research and Splicing
Sex and Gender in Healthcare
Adipokines, Inflammation, and Metabolic Diseases
Signaling Pathways in Disease
Mitochondrial Function and Pathology
Cardiac Arrhythmias and Treatments
Angiogenesis and VEGF in Cancer
Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Cardiac Valve Diseases and Treatments
Congenital Heart Disease Studies
Cardiovascular Effects of Exercise
Heart Failure Treatment and Management
Neuroinflammation and Neurodegeneration Mechanisms