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Nature Reviews Rheumatology

Nature Reviews Rheumatology is a specialist journal in rheumatology publishing review articles, perspectives, news and comment, correspondence, research highlights and curated collections on autoimmune, inflammatory and musculoskeletal diseases.

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Subject Rheumatology
Impact Factor 32.7
Quartile Q1
Open Access Type Closed
ISSN 1759-4790
eISSN 1759-4804
Invitation Only Yes
Cost Range No fee for publication.

Submission Instructions

Nature Reviews Rheumatology is an invitation-only journal. Submissions are accepted by invitation from the editorial board only. The following article types are accepted:

Review-Type Articles

Cover Letter Cover Letter requirements are not specified.
Abstract An unstructured abstract is required. Abstract should ideally be no more than 200 words. Abstract must be unstructured.
Manuscript Manuscript should include an introduction without subheadings and end with a brief concluding summary section without subheadings. Manuscript must include 4–6 key points of no more than 30 words each, and any use of an LLM must be documented in the Methods section or another suitable part of the manuscript if no Methods section is available.
References References should be approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited as superscript numbers in sequential order, and if a reference has six or more authors only the first author should be listed followed by 'et al.'.
Figures & Tables No more than 7 display items, including tables, figures and boxes, are allowed. Tables must be provided as part of the article document, while tables containing graphical content must be supplied as separate image files. Display items must be cited in the main text in order in the format (FIG. 1), each figure must have a concise legend with a short title describing all components and defining abbreviations, and all abbreviations in tables must be defined.
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Technical Review

Cover Letter Cover Letter requirements are not specified.
Abstract An unstructured abstract is required. Abstract should ideally be a maximum of 200 words. Abstract must be unstructured.
Manuscript Manuscript must begin with an introductory section without subheadings and end with a brief concluding summary section without subheadings. Competing interests must be declared within the text of the article, and any use of an LLM must be documented in the Methods section or another suitable part of the manuscript.
References References should be approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited as superscript numbers in sequential order, and if a reference has six or more authors only the first author should be listed followed by 'et al.'.
Figures & Tables No more than 7 display items, including tables, figures and boxes, are allowed. Tables must be provided as part of the article document, while tables containing graphical content must be supplied as separate image files. Display items must be cited in the main text in order in the format (FIG. 1), each figure must have a concise legend with a short title describing all components and defining abbreviations, and all abbreviations in tables must be defined.
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Consensus Statement

Cover Letter Cover Letter requirements are not specified.
Abstract An unstructured abstract is required. Abstract should ideally be no more than 200 words. Abstract must be unstructured.
Manuscript Manuscript must include an introduction without subheadings, a required Methods section describing methodology and stakeholders, and a brief concluding section without subheadings. No more than seven display items in total are allowed, competing interests must be declared within the text, LLM use must be documented in the Methods section or another suitable section if no Methods section is available, and authors may optionally provide significance statements for 5–10% selected key references.
References References should be approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited as superscript numbers sequentially and listed in the order of main text, tables, figures, and then boxes, with only the first author followed by 'et al.' when there are six or more authors.
Figures & Tables No more than seven display items, including tables, figures, and boxes, are allowed. Tables should be provided as part of the article document, tables containing graphical content must be provided as separate image files, and supplementary information must be supplied as a single file if included. Tables must be clear with every cell completed and abbreviations defined, and figures must be fully labelled and include a short title with a concise legend of approximately 200 words defining all abbreviations.
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Evidence-Based Guidelines

Cover Letter Cover Letter requirements are not specified.
Abstract An unstructured abstract is required. The abstract should ideally be no more than 200 words. The abstract must be unstructured.
Manuscript The manuscript must include an introduction without subheadings, a Methods section describing methodology and stakeholders, and a brief concluding section without subheadings, with no more than three heading levels overall. Competing interests must be declared within the text of the article, and authors may optionally identify 5–10% of references as key references with a one-sentence significance statement for each.
References References should be approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited sequentially as superscript numbers and listed in the order of main text, tables, figures, and then boxes, with only the first author followed by 'et al.' when there are six or more authors.
Figures & Tables No more than 7 display items, including tables, figures, and boxes, are allowed. Tables should be provided as part of the article document, while supplementary information, if included, must be supplied as a single file. All table cells must contain an entry and all table abbreviations must be defined, and each figure must be fully labelled with a short title and a concise legend of approximately 200 words defining abbreviations.
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Correspondence

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Main text must not exceed 500 words. No more than two levels of headings are allowed, and the first paragraph must cite the original article. Competing interests must be included in the manuscript file, and any use of an LLM must be documented in the Methods section or another suitable part of the manuscript if no Methods section is available.
References Reference lists must not contain more than 10 references. References must use Nature Reviews reference style. References must be cited sequentially in the order of main text, tables, figures, and then boxes, and references with six or more authors should list only the first author followed by 'et al.'.
Figures & Tables Only one display item can be included. Tables and boxes must be provided as part of the article document. Definitions of all abbreviations used in tables and figures must be provided, and tables should preferably fit on one portrait-oriented A4 page.
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Expert Recommendation

Cover Letter Cover Letter requirements are not specified.
Abstract An unstructured abstract is required. The abstract should ideally be no more than 200 words. The abstract must be unstructured.
Manuscript The manuscript must include an introduction without subheadings, allow no more than three levels of headings, and end with a brief concluding section without subheadings. Competing interests must be included in the manuscript file, and authors may optionally identify 5–10% of references as key references with a one-sentence significance statement for each.
References References should be approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited sequentially as superscript numbers and listed in the order of main text, tables, figures, and then boxes.
Figures & Tables No more than 7 display items, including tables, figures, and boxes, are allowed. Supplementary information, if included, must be supplied as a single file. Tables must have an entry in every cell and define all abbreviations, and each figure must be fully labelled with a short title and a concise legend of approximately 200 words defining all abbreviations.
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Recent Publications

Treat-to-target in Behçet syndrome

Alessandra Bettiol, George Bertsias, Bahram Bodaghi, Aykut Ferhat Celik, George E. Fragoulis, David Saadoun, Rosaria Talarico, Uğur Uygunoğlu, Giacomo Emmi, Petros P. Sfikakis, Gülen Hatemi

10.1038/s41584-026-01381-7
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Lytic cell death turns TRIM21 into an autoantigen

Jessica McHugh

10.1038/s41584-026-01387-1
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Treatment strategies in giant cell arteritis and polymyalgia rheumatica: beyond glucocorticoids

Francesco Muratore, Kenneth J. Warrington, Christian Dejaco, Maria C. Cid, Bernhard Hellmich, Ann W. Morgan, Stefania Croci, Carlo Salvarani

10.1038/s41584-026-01379-1
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T cells mediate tissue damage in lupus nephritis

Holly Webster

10.1038/s41584-026-01382-6
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Brepocitinib shows promise for dermatomyositis

Sarah Onuora

10.1038/s41584-026-01383-5
View Publication

Frequently asked questions

How long does it take to publish?

Median time from submission to first editorial decision is 12 days. Median time from submission to acceptance is 193 days.

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Is a cover letter required?

Proposals for Review-type and Comment-type articles should be submitted as a synopsis consisting of a 200-word abstract, a brief description of the main article sections, a list of key references, and the list of authors and their affiliations.

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What are the publication costs?

No fee for publication. Immediate gold open access is not offered; articles are published via the subscription route.

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Research Topics

Rheumatoid Arthritis Research and Therapies Systemic Lupus Erythematosus Research Osteoarthritis Treatment and Mechanisms Autoimmune and Inflammatory Disorders Research Spondyloarthritis Studies and Treatments Systemic Sclerosis and Related Diseases T-cell and B-cell Immunology Immune Cell Function and Interaction Monoclonal and Polyclonal Antibodies Research Inflammasome and immune disorders Cytokine Signaling Pathways and Interactions Psoriasis: Treatment and Pathogenesis Bone Metabolism and Diseases Gout, Hyperuricemia, Uric Acid Vasculitis and related conditions Inflammatory mediators and NSAID effects Bone health and treatments Fibromyalgia and Chronic Fatigue Syndrome Research Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Chronic Lymphocytic Leukemia Research Bone health and osteoporosis research Inflammatory Myopathies and Dermatomyositis Musculoskeletal pain and rehabilitation Diabetes and associated disorders Cell Adhesion Molecules Research