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Nature Reviews Nephrology

Nature Reviews Nephrology publishes Reviews, Clinical Outlooks, Comments, World Views, Research Highlights and related content focused on kidney disease, nephrology research, diagnosis, therapeutics and patient care.

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Impact Factor 39.8
Quartile Q1
Open Access Type Closed
ISSN 1759-5061
eISSN 1759-507X
Invitation Only Yes
Cost Range We do not charge a fee for publication.

Submission Instructions

Nature Reviews Nephrology is an invitation-only journal. Submissions are accepted by invitation from the editorial board only. The following article types are accepted:

Review-Type Articles

Cover Letter Cover Letter requirements are not specified.
Abstract An unstructured abstract is required. Abstract should ideally be no more than 200 words. Abstract must be unstructured.
Manuscript Manuscript must include an introductory section without subheadings and end with a brief concluding summary section without subheadings, with a maximum of three heading levels allowed. Manuscript must include competing interests in the file, key points as 4–6 bullet points of 30 words or fewer, and documentation of any Large Language Model use in the Methods section or another suitable section if no Methods section is available.
References References should be approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited as sequential superscript numbers and listed in the order of citation across the main text, tables, figures, and then boxes, with six or more authors abbreviated to the first author followed by 'et al.'.
Figures & Tables Display items are limited to 7 or fewer tables, figures, and boxes combined. Tables and boxes must be provided as part of the article document, while graphical tables must be provided as separate image files. Display items must be cited in the main text in order in the format (FIG. 1), tables must have at least three columns with every cell populated and abbreviations defined, and all figures must be fully labelled with a short title and brief legend describing all components and abbreviations.
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Technical Review

Cover Letter Cover Letter requirements are not specified.
Abstract An unstructured abstract is required. Abstract should ideally be no more than 200 words. Abstract must be unstructured.
Manuscript Manuscript must include an introduction without subheadings and end with a brief concluding summary section without subheadings, with a maximum of three heading levels overall. Competing interests must be included in the manuscript file, and any use of a large language model must be documented in the Methods section or another suitable part of the manuscript if no Methods section is available.
References References should be approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited as sequential superscript numbers and listed in the order of citation in the main text, tables, figures, and then boxes, with only the first author followed by 'et al.' when a reference has six or more authors.
Figures & Tables Display items are limited to 7 or fewer tables, figures, and boxes combined. Tables and boxes must be provided as part of the article document, while graphical tables must be provided as separate image files. Display items must be cited in the main text in order, tables must have no legend and at least three columns of data, and all figures must be fully labelled with a short title and brief legend defining abbreviations.
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Consensus Statement

Cover Letter Cover Letter requirements are not specified.
Abstract An unstructured abstract is required. Abstract should ideally be no more than 200 words. Abstract must be unstructured.
Manuscript Manuscript must include an introductory section without subheadings, a Methods section describing methodology and stakeholders, and a brief concluding summary section without subheadings. Manuscript must include competing interests in the file, document any LLM use in the Methods section or suitable alternative part, and use no more than three levels of headings.
References References must use Nature Reviews style. References must be cited as superscript numbers and listed in the order main text, tables, figures, then boxes.
Figures & Tables No more than 7 display items, including tables, figures and boxes, are allowed. Tables must be provided as part of the article document, and if supplementary information is included, it must be supplied as a single file. Display items must be cited in the main text in order in the format (FIG. 1), tables must not have legends and all table cells and abbreviations must be completed and defined, and each figure must be fully labelled with a short title and concise legend.
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Evidence-Based Guidelines

Cover Letter Cover Letter requirements are not specified.
Abstract An unstructured abstract is required. The unstructured abstract should ideally be no more than 200 words. The abstract must be unstructured. No headings are required because the abstract must be unstructured.
Manuscript The manuscript must include an introductory section without subheadings, a Methods section describing methodology and stakeholders, no more than three levels of headings, and a brief concluding summary section without subheadings at the end. The manuscript must include competing interests in the file, document any LLM use in the Methods section or a suitable alternative part, and ensure all information mentioned in the abstract is addressed in the main article.
References References should be approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited sequentially as superscript numbers and listed in the order main text, tables, figures, then boxes, with six or more authors shortened to the first author followed by 'et al.'.
Figures & Tables No more than 7 display items, including tables, figures and boxes, are allowed. Tables and boxes must be provided as part of the article document, and supplementary information, if included, must be supplied as a single file. Tables must not have legends and must define all abbreviations, while each figure must be fully labelled and accompanied by a short title and a concise legend of approximately 200 words that describes all components and defines all abbreviations.
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Roadmap

Cover Letter Cover Letter requirements are not specified.
Abstract An unstructured abstract is required. Abstract should ideally be no more than 200 words. Abstract must be unstructured.
Manuscript Manuscript must include an introduction without subheadings and end with a brief concluding summary section without subheadings, with a maximum of three heading levels allowed. Competing interests must be included in the manuscript file, and any use of a large language model must be documented in the Methods section or another suitable section if no Methods section is available.
References References should be approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited as sequential superscript numbers and listed in the order of main text, tables, figures, and then boxes.
Figures & Tables Display items are limited to 7 or fewer tables, figures, and boxes combined. Tables and boxes must be provided as part of the article document, while graphical tables must be provided as separate image files. Display items must be cited in the main text in order, tables must have no legend and contain at least three columns with every cell completed, and all figures must be fully labelled with a short title and concise legend defining abbreviations.
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Correspondence

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Main text must not exceed 500 words. The first paragraph must cite the original article, and no more than two levels of headings are allowed. Competing interests must be declared within the text of the article and use of an LLM must be documented in a suitable part of the manuscript if applicable.
References References are limited to a maximum of 10. References must use Nature Reviews reference style. References must be cited as superscript numbers sequentially in the order of appearance in the main text, tables, figures, and then boxes, and for works with six or more authors only the first author should be listed followed by 'et al.'.
Figures & Tables Only one display item can be included. Tables must be provided as part of the article document, while supplementary items should be submitted as a single document where possible. Tables must not include a legend but may include footnotes, and figures must have a concise legend with all abbreviations defined.
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Expert Recommendation

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should ideally be no more than 200 words. Abstract must be unstructured.
Manuscript Manuscript must begin with an introduction without subheadings, allow no more than three levels of headings, and end with a brief concluding summary section without subheadings. Competing interests must be included in the manuscript file, and any use of an LLM must be documented in the Methods section or another suitable section if no Methods section is available.
References References should be approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited sequentially as superscript numbers and listed in the order of appearance in the main text, tables, figures, and then boxes.
Figures & Tables No more than 7 display items, including tables, figures and boxes, are allowed. Tables and boxes must be provided as part of the article document. Each figure must be fully labelled with a short title and concise legend defining abbreviations, tables must have all cells completed with abbreviations defined and no legend, and display items must be cited in the main text in order in the format (FIG. 1).
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Recent Publications

The pathophysiology of pre-eclampsia

Annemarie Hennessy, Jolene Ng, Angela Makris

10.1038/s41581-026-01085-x
View Publication

Gene–disease relationships for glomerular phenotypes: expert recommendations from ClinGen

Alicia B. Byrne, Anna S. Li, Edmund Y. M. Chung, Enyonam Edoh, Hannah Dziadzio, Pamela Ajuyah, Elisabet Ars, Yasar Caliskan, Ahmet Burak Dirim, Mark D. Elliott, Asheeta Gupta, Kushani Jayasinghe, Andrew J. Mallett, Julie C. Ratliff, Matthew G. Sampson, Judy Savige, Johannes S. Schlondorff, Zornitza Stark, Ryan F. Webb, Parker C. Wilson, Janewit Wongboonsin, Hande Aypek, Agnieszka Bierzynska, Edmund YM Chung, Rasheed Gbadegesin, Julia Hoefele, Lisa Kim, Anna S. Li, Albertien M. van Eerde, Martin R. Pollak, Hugh J. McCarthy, Catherine Quinlan, Rachel Lennon

10.1038/s41581-026-01087-9
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Anti-neutrophil cytoplasmic antibody-associated vasculitis: biological insights and biomarker-guided disease management

Marilina Antonelou, Kashif Jamil Anwari, Alan D. Salama

10.1038/s41581-026-01081-1
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Selective autophagy in kidney health and disease

Ying Fu, Man J. Livingston, Guie Dong, Anqun Chen, Juan Cai, Zheng Dong

10.1038/s41581-026-01082-0
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Author Correction: The genetics of hypertension

Gabriel Stölting, Kieu Nhi Tran Vo, Janek Haus, Ute I. Scholl

10.1038/s41581-026-01088-8
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Frequently asked questions

How long does it take to publish?

Median time from submission to first editorial decision is 16 days. Median time from submission to acceptance is 156 days.

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What are the publication costs?

The journal uses the subscription publication route and does not charge a fee for publication.

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Research Topics

Chronic Kidney Disease and Diabetes Renal Diseases and Glomerulopathies Dialysis and Renal Disease Management Renal and related cancers Acute Kidney Injury Research Renal Transplantation Outcomes and Treatments Blood Pressure and Hypertension Studies Organ Donation and Transplantation Genetic and Kidney Cyst Diseases Organ Transplantation Techniques and Outcomes Birth, Development, and Health Renal and Vascular Pathologies Parathyroid Disorders and Treatments Diabetes Treatment and Management Biomedical Research and Pathophysiology Renal function and acid-base balance Electrolyte and hormonal disorders Complement system in diseases Hormonal Regulation and Hypertension Muscle and Compartmental Disorders Renal cell carcinoma treatment Sodium Intake and Health Pancreatic function and diabetes Systemic Lupus Erythematosus Research Ion Transport and Channel Regulation