Overview
Submission Instructions
Recent Publications
Frequently Asked Questions
Research Topics
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Nature Immunology is a journal covering immunology research and publishes content including Articles, Review Articles, Resources, Research Briefings, News & Views and Research Highlights.
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Subject
Immunology
Impact Factor
27.6
Quartile
Q1
Open Access Type
Hybrid
ISSN
1529-2908
eISSN
1529-2916
Invitation Only
No
Cost Range
Article processing charge applies for open access publication; institutional agreements may cover the APC.
Submission Instructions
Nature Immunology accepts the following article types. Click on an article type to view submission instructions.
Article
Cover Letter
A cover letter is required. Cover letter must explain the importance of the work and why it is appropriate for the diverse readership of Nature Immunology, and if double-blind peer review is chosen it must include the affiliation and contact information for all authors.
Abstract
An abstract is required. Abstract must be no more than 150 words. Abstract must be unstructured and unreferenced.
Manuscript
Main text must be 3,000–4,000 words excluding the abstract, Online Methods, references, and figure legends. Manuscript must be divided into an Introduction without a heading, Results, Discussion, and Online Methods, with topical subheadings in Results and Online Methods but no subheadings in Discussion. Manuscript must include Methods, figures if applicable, a reference list, and documentation of any Large Language Model use in the Methods section or another suitable part of the manuscript if no Methods section is available.
References
References are recommended to be up to 50.
Figures & Tables
A maximum of 8 display items consisting of figures and/or tables is permitted.
Letter
Cover Letter
A cover letter is required. Cover letter must explain the importance of the work and why it is appropriate for the diverse readership of Nature Immunology, and if double-blind peer review is chosen it must include the affiliation and contact information for all authors.
Abstract
An abstract is not required because the Letter must begin with an introductory paragraph instead. The introductory paragraph must be up to 150 words. The article uses an unstructured introductory paragraph instead of an abstract.
Manuscript
Main text must be up to 2,500 words, excluding the introductory paragraph, online Methods, references and figure legends. The manuscript must begin with a referenced introductory paragraph and must not be divided by headings except for the online Methods headings. Use of a Large Language Model must be documented in the Methods section or, if no Methods section is available, in a suitable alternative part of the manuscript.
References
References are recommended to be up to 30.
Figures & Tables
Display items must be 5 figures and/or tables.
Resource
Cover Letter
A cover letter is required. Cover letter must explain the importance of the work and why it is appropriate for the diverse readership of Nature Immunology, and if double-blind peer review is chosen it must include the affiliation and contact information for all authors.
Abstract
An abstract is required. Abstract must be 100–150 words. Abstract must be unstructured and unreferenced.
Manuscript
Main text must be 3,000–4,000 words, excluding abstract, online Methods, references and figure legends. Manuscript must be divided into Introduction without a heading, Results, Discussion, and Online Methods, with topical subheadings in Results and Online Methods but no subheadings in Discussion. Use of a Large Language Model must be documented in the Methods section or, if a Methods section is not available, in a suitable alternative part of the manuscript.
References
References are recommended to be up to 50.
Figures & Tables
Display items, including figures and/or tables, are limited to 8 items.
Review
Cover Letter
A cover letter is required. Cover letter must explain the importance of the work, why it suits the journal’s broad readership, and whether there were prior discussions with an editor.
Abstract
Abstract requirements are not specified.
Manuscript
Review main text must be 3,000–4,000 words. Review must not include original previously unpublished research findings and may contain only minimal new supporting data. Manuscript must include a reference list, and illustrations are strongly encouraged.
References
Review may include up to 100 references, with exceptions possible in special cases. Citations should be selective, and short annotations explaining the importance of key studies are required when such studies comprise 10% or less of all references.
Figures & Tables
A maximum of ten Extended Data display items is permitted.
Correspondence
Cover Letter
A cover letter is required. Cover letter must explain the importance of the work and its suitability for the diverse readership of Nature Immunology, state whether there were prior discussions with a Nature Immunology editor, and include author affiliations and contact information if double-blind peer review is chosen.
Abstract
Abstract requirements are not specified.
Manuscript
Correspondence must be 300–800 words. Correspondence should not include original unpublished research findings and may contain only minimal new supporting data.
References
Correspondence may include up to 10 references. Reference lists must omit article titles.
Figures & Tables
Correspondence may include 1 display item.
Recent Publications
Author Correction: Short IL-18 generated by caspase-3 cleavage mobilizes NK cells to suppress tumor growth
Junchen Shen, Yu Zhang, Wenbo Tang, Mingxia Yang, Tong Cheng, Yihui Chen, Shi Yu, Qiuhong Guo, Limin Cao, Xun Wang, Hui Xiao, Lanfeng Wang, Chengyuan Wang, Chen-Ying Liu, Guangxun Meng
10.1038/s41590-026-02662-9
View Publication
Frequently asked questions
How long does it take to publish?
Decisions on whether to send a manuscript for peer review are normally made within 2 working days of receipt. Decisions about publication are typically made within 2 days of receipt of the referees' reports.
Reformat to Nature Immunology using Livewrite PremiumIs a cover letter required?
A cover letter is required. It should explain the importance of the work and its suitability for the readership, disclose related manuscripts under consideration or in press elsewhere, note any prior discussions with an editor, include author affiliation and contact information if double-blind peer review is chosen, and may optionally recommend or exclude reviewers.
Reformat to Nature Immunology using Livewrite PremiumWhat are the publication costs?
Hybrid journal.
Reformat to Nature Immunology using Livewrite PremiumResearch Topics
Immune Cell Function and Interaction
T-cell and B-cell Immunology
Immunotherapy and Immune Responses
Immune Response and Inflammation
interferon and immune responses
IL-33, ST2, and ILC Pathways
Immune cells in cancer
CAR-T cell therapy research
Inflammasome and immune disorders
NF-κB Signaling Pathways
Cancer Immunotherapy and Biomarkers
Neuroinflammation and Neurodegeneration Mechanisms
Cytokine Signaling Pathways and Interactions
Immunodeficiency and Autoimmune Disorders
Immune responses and vaccinations
Monoclonal and Polyclonal Antibodies Research
Cell Adhesion Molecules Research
Diabetes and associated disorders
Epigenetics and DNA Methylation
Single-cell and spatial transcriptomics
HIV Research and Treatment
SARS-CoV-2 and COVID-19 Research
Phagocytosis and Immune Regulation
Ubiquitin and proteasome pathways
Neutrophil, Myeloperoxidase and Oxidative Mechanisms
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