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Nature Genetics

Nature Genetics publishes genetics and genomics research and related content including Articles, Review Articles, Perspectives, Correspondence, Research Briefings, News & Views and Research Highlights.

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Impact Factor 29
Quartile Q1
Open Access Type Hybrid
ISSN 1061-4036
eISSN 1546-1718
Invitation Only No
Cost Range English language editing starts at $87. Scientific editing starts at $1545.

Submission Instructions

Nature Genetics accepts the following article types. Click on an article type to view submission instructions.

Research Articles

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Research Articles containing newly developed code central to the paper’s main claims must provide details of the code for peer review evaluation.
References References requirements are not specified.
Figures & Tables Figures & Tables requirements are not specified.
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Recent Publications

Telomere-to-telomere genome assemblies and population resequencing of diploid and allotetraploid peanut varieties

Jianxin Bian, Yilin Zhang, Shuai Ding, Haosong Guo, Kui Li, Yu Guan, Guoliang Zhou, Jihua Li, Vanika Garg, Yuanyuan Cui, Yuan Lv, Annapurna Chitikineni, Qingjing Meng, Tianyu Li, Liangqiong He, Chuanzhi Zhao, Xingjun Wang, Ronghua Tang, Liangsheng Zhang, Xing Wang Deng, Rajeev K. Varshney, Hang He, Xiaoqin Liu

10.1038/s41588-026-02577-z
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Mosaic integration of spatial multi-omics with SpaMosaic

Xuhua Yan, Zhaoyu Fang, Kok Siong Ang, Lynn van Olst, Alex Edwards, Thomas Watson, Ruiqing Zheng, Di Zhang, Rong Fan, Min Li, David Gate, Jinmiao Chen

10.1038/s41588-026-02573-3
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Publisher Correction: Biallelic variants in RNU2-2 cause the most prevalent known recessive neurodevelopmental disorder

Daniel Greene, Rodrigo Mendez, Jon Lees, Mafalda Barbosa, Alessandro Bruselles, Luigi Chiriatti, Federico Ferraro, Cecilia Mancini, Rachel Schot, Frank Sleutels, Enrico Bertini, Devon E. Bonner, Arjan Bouman, Alice S. Brooks, T homas A. Cassini, Kimberly M. Ezell, Natalia Gomez-Ospina, Tjitske Kleefstra, Michael O’Donoghue, Lynette Rives, Vandana Shashi, Rebecca C. Spillmann, Mohamed Wafik, Kathleen Freson, Tahsin Stefan Barakat, Marco Tartaglia, Jonathan A. Bernstein, Andrew D. Mumford, Matthew T. Wheeler, Ernest Turro

10.1038/s41588-026-02605-y
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Genomic analyses implicate hormonal and metabolic dysregulation in polycystic ovary syndrome

Loes M. E. Moolhuijsen, Jia Zhu, Benjamin H. Mullin, Natàlia Pujol-Gualdo, Ky’Era V. Actkins, Jasmine A. Mack, Hridya Rao, Bhavi Trivedi, Katherine A. Kentistou, Yajie Zhao, David Westergaard, Jaakko S. Tyrmi, Gudmar Thorleifsson, Yanfei Zhang, Laura Wittemans, Amber DeVries, Kelly Brewer, Ryan Sisk, Rebecca Danning, Michael H. Preuss, Michelle R. Jones, Katherine S. Ruth, Marianne Andersen, Ricardo Azziz, Karina Banasik, Michael Boehnke, Linda Broer, Søren Brunak, Yee-Ming Chan, Daniel I. Chasman, Mark Daly, David A. Ehrmann, Bart C. Fauser, Lars G. Fritsche, M. Geoffrey Hayes, Chunyan He, Hongyan Huang, Irina Kowalska, Peter Kraft, Richard S. Legro, Nan Lin, Ruth J. Loos, Yvonne V. Louwers, Reedik Magi, Mark I. McCarthy, Laure Morin-Papunen, Jean V. Morrison, Cynthia Morton, Girish N. Nadkarni, Benjamin M. Neale, Henriette Svarre Nielsen, Mette Nyegaard, Sisse R. Ostrowski, Ole B. V. Pedersen, Erik Sørensen, Christina Mikkelsen, Christian Erikstrup, Kathrine A. Kaspersen, Mie T. Bruun, Bitten Aagaard, Henrik Ullum, Barbara Obermayer-Pietsch, Aarno Palotie, Mary P. Reeve, Andres Salumets, Richa Saxena, Timothy D. Spector, Bronwyn G. A. Stuckey, Unnur Thorsteinsdottir, André G. Uitterlinden, Margrit Urbanek, Sebastian Zöllner, David A. van Heel, Henrik Ullum, Adam Auton, Alan Kwong, Anjali J. Shastri, Barry Hicks, Catherine H. Weldon, David A. Hinds, Emily DelloRusso, Emily M. Rios, Joyce Y. Tung, Kahsaia de Brito, Katelyn Kukar Bond, Keng-Han Lin, Matthew H. McIntyre, Matthew J. Kmiecik, Qiaojuan Jane Su, Robert K. Bell, Sayantan Das, Shubham Saini, Stella Aslibekyan, Vinh Tran, Wanwan Xu, Alisa P. Lehman, Noura S. Abul-Husn, R. Ryanne Wu, Rebecca M. K. Berns, Ruth I. Tennen, Stacey B. Detweiler, Aditya Ambati, Anna Guan, Bertram L. Koelsch, Chris German, Éadaoin Harney, Ethan M. Jewett, G. David Poznik, James R. Ashenhurst, Jingran Wen, Peter R. Wilton, Steven J. Micheletti, William A. Freyman, David A. van Heel, Joel N. Hirschhorn, Kari Stefansson, John R. B. Perry, Unnur Styrkarsdottir, Scott G. Wilson, Terhi Piltonen, Triin Laisk, Marjo-Riitta Jarvelin, Kharis Burns, Anne E. Justice, Hannele Laivuori, Ken K. Ong, Mark O. Goodarzi, Lea K. Davis, Andrea Dunaif, Cecilia M. Lindgren, Joop S. E. Laven, Stephen Franks, Jenny A. Visser, Corrine K. Welt, Tugce Karaderi, Felix R. Day

10.1038/s41588-026-02543-9
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Systematic design of combination therapy by targeting master regulators of coexisting diffuse midline glioma cell states

Ester Calvo Fernández, Lorenzo Tomassoni, Xu Zhang, Junqiang Wang, Aleksandar Obradovic, Pasquale Laise, Aaron T. Griffin, Lukas Vlahos, Hanna E. Minns, Diana V. Morales, Christian Simmons, Matthew Gallitto, Hong-Jian Wei, Timothy J. Martins, Pamela S. Becker, John R. Crawford, Theophilos Tzaridis, Robert J. Wechsler-Reya, James Garvin, Robyn D. Gartrell, Luca Szalontay, Stergios Zacharoulis, Cheng-Chia Wu, Zhiguo Zhang, Andrea Califano, Jovana Pavisic

10.1038/s41588-026-02550-w
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Research Topics

Genetic Associations and Epidemiology Genomics and Chromatin Dynamics Epigenetics and DNA Methylation RNA modifications and cancer RNA Research and Splicing Cancer Genomics and Diagnostics CRISPR and Genetic Engineering Genomic variations and chromosomal abnormalities Chromosomal and Genetic Variations Genetic Mapping and Diversity in Plants and Animals Genomics and Rare Diseases RNA and protein synthesis mechanisms Genetics and Neurodevelopmental Disorders Gene expression and cancer classification DNA Repair Mechanisms Bioinformatics and Genomic Networks Mitochondrial Function and Pathology Genomics and Phylogenetic Studies Genetic Syndromes and Imprinting Genetic Neurodegenerative Diseases Genetic factors in colorectal cancer Cancer-related gene regulation Cancer-related molecular mechanisms research Congenital heart defects research Single-cell and spatial transcriptomics