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Nature Reviews Cancer

Nature Reviews Cancer is a journal in the Nature Reviews portfolio covering cancer research and oncology, publishing article formats including Review Articles, Progress articles, Comments, Research Highlights, Journal Club, Expert Recommendations and Tools of the Trade.

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Subject Oncology
Impact Factor 66.8
Quartile Q1
Open Access Type Hybrid
ISSN 1474-175X
eISSN 1474-1768
Invitation Only Yes
Cost Range Institutional online access is available for institutions and organizations to purchase through a Springer Nature institutional licence.

Submission Instructions

Nature Reviews Cancer is an invitation-only journal. Submissions are accepted by invitation from the editorial board only. The following article types are accepted:

Review-Type

Cover Letter Cover Letter requirements are not specified.
Abstract A 200-word abstract is required as part of the synopsis submission for Review-Type articles. The synopsis abstract must be 200 words.
Manuscript Review-Type articles should present an unbiased overview of a field or topic and include a fair discussion. The synopsis must include a brief description of the main article sections, a list of key references, and the list of authors and their affiliations.
References The synopsis must include a list of key references.
Figures & Tables Figures & Tables requirements are not specified.
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Perspective

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should ideally be no more than 200 words. Abstract must be unstructured.
Manuscript Manuscript should begin with an introduction without subheadings and end with a brief concluding summary section without subheadings. Manuscript must include a competing interests declaration in the file, document any large language model use in the Methods section or another suitable section if no Methods section is available, and Perspective articles must clearly distinguish generally accepted views from personal perspectives.
References References must use Nature Reviews style. References must be cited as sequential superscript numbers, and for works with six or more authors only the first author should be listed followed by 'et al.'.
Figures & Tables Display items are limited to 5 or fewer tables, figures, and boxes combined. Tables and boxes must be provided as part of the article document. Display items must be cited in the main text in order as (FIG. 1), tables must have a short title, and figures must be fully labelled with a short title and concise legend.
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Consensus Statement

Cover Letter Cover Letter requirements are not specified.
Abstract An unstructured abstract is required. The abstract should ideally be no more than 200 words. The abstract must be unstructured.
Manuscript The manuscript must include an introduction without subheadings, a Methods section describing methodology and stakeholders, and a brief concluding section without subheadings. Competing interests must be declared in the article text, writing assistance must be acknowledged, funding arising directly from a grant must be declared in a separate funding statement, and use of a large language model must be documented in the Methods section or another suitable section if no Methods section is available.
References References should be used at approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited sequentially as superscript numbers, list six or more author papers as the first author followed by 'et al.', and be ordered as cited from the main text, then tables, figures, and boxes.
Figures & Tables No more than 7 display items, including tables, figures, and boxes, are allowed. Boxes and tables should be provided as part of the article document. Display items must be cited in the main text in order in the format (FIG. 1), and tables, figures, and boxes must each have a short title or legend as applicable.
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Evidence-Based Guidelines

Cover Letter Cover Letter requirements are not specified.
Abstract An unstructured abstract is required. The abstract should ideally be no more than 200 words. The abstract must be unstructured.
Manuscript The manuscript must include an introduction without subheadings, a required Methods section describing methodology and stakeholders, and a brief concluding section without subheadings. Use of a large language model must be documented in the Methods section or another suitable section if no Methods section is available.
References References should be used at approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited sequentially as superscript numbers, list only the first author followed by 'et al.' when there are six or more authors, and be ordered as main text, tables, figures, then boxes.
Figures & Tables No more than 7 display items, including tables, figures, and boxes, are allowed. Tables and boxes should be provided as part of the article document. Display items must be cited in the main text in order in the format (FIG. 1).
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Recent Publications

Remembering inflammation increases cancer risk

Daniela Senft

10.1038/s41568-026-00938-8
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Stem cells as an essential mediator of the exercise–tumorigenesis link

Xueqian Zhuang, Emily S. Wong, Tuomas Tammela, Lee W. Jones

10.1038/s41568-026-00933-z
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Microplastics but macro-concerns on the brain

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10.1038/s41568-026-00937-9
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The sleeping threat: targeting cancer dormancy to transform metastasis therapy

Julio A. Aguirre-Ghiso, Jose Javier Bravo-Cordero, Wenjun Guo, Gregoire Lauvau, Maria Soledad Sosa

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Enhancer and metabolic rewiring by KMT2C–COMPASS or KMT2D–COMPASS family loss in cancer creates druggable vulnerabilities

Zibo Zhao, Ali Shilatifard

10.1038/s41568-026-00919-x
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Frequently asked questions

How long does it take to publish?

Accepted manuscripts may be self-archived for public release 6 months after first publication.

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What are the publication costs?

Articles can only be published using the subscription publication route; immediate gold open access is not offered.

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Research Topics

Cancer Genomics and Diagnostics Epigenetics and DNA Methylation Cancer-related Molecular Pathways Cancer Cells and Metastasis Cancer, Hypoxia, and Metabolism Ubiquitin and proteasome pathways RNA modifications and cancer DNA Repair Mechanisms Cancer Immunotherapy and Biomarkers Immunotherapy and Immune Responses Cancer Research and Treatments CAR-T cell therapy research Immune Cell Function and Interaction Protein Degradation and Inhibitors Genomics and Chromatin Dynamics Microtubule and mitosis dynamics Immune cells in cancer CRISPR and Genetic Engineering Genetic factors in colorectal cancer Angiogenesis and VEGF in Cancer RNA Research and Splicing BRCA gene mutations in cancer Cancer-related gene regulation Histone Deacetylase Inhibitors Research Lung Cancer Treatments and Mutations

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