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Neurobiology of Disease

Neurobiology of Disease is a major international open access journal at the interface between basic and clinical neuroscience. It publishes research and review papers on molecular and cellular disease mechanisms, neural systems and behavioral disorders, genetics of inherited neurological and psychiatric diseases, nervous system aging, and findings relevant to the development of new therapies. The journal also welcomes negative results when authors provide strong justification for the importance of the observations.

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Subject Neurosciences
Impact Factor 5.6
Quartile Q1
Open Access Type Open
ISSN 0969-9961
eISSN 1095-953X
Invitation Only No
Cost Range Article Publishing Charge: USD 4060 excluding taxes for all articles.

Submission Instructions

Neurobiology of Disease accepts the following article types. Click on an article type to view submission instructions.

Research Papers

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 250 words. Abstract must be unstructured. Abstract must briefly state the purpose of the research, methods, principal results, and major conclusions.
Manuscript Manuscript must be divided into clearly defined sections using headings. Submission must include 1 to 7 English keywords, 3 to 5 highlights bullets of no more than 85 characters each, a separate acknowledgements section before the references, competing interest and funding declarations, and a declaration of any generative AI use in writing.
References References may be submitted in any consistent style, but in-text citations must use author-date format. Reference list must be arranged alphabetically and then chronologically if needed, include full bibliographic details, abbreviate journal names according to LTWA, and use first author et al. in text for works with three or more authors.
Figures & Tables Tables must be submitted as editable text and figures must be supplied as separate files along with the manuscript. Tables must be cited in the text, numbered consecutively, and include captions, and figures must be cited in the text, numbered in sequence, and include captions explaining symbols and abbreviations.
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Review Papers

Cover Letter Cover letter is required and must clearly state that the rules on AI were followed. Cover letter must clearly state that the rules on AI were followed.
Abstract Abstract is required. Abstract must not exceed 250 words.
Manuscript Manuscript must be divided into clearly defined sections using headings and, for Review Papers, should present a justified, comprehensive, unbiased review with perspective on the field and acknowledgment of controversies. Submission must include 1 to 7 English keywords, 3 to 5 highlights of no more than 85 characters each, a declaration of competing interests, a declaration of generative AI use, and tables summarizing key findings unless justified otherwise.
References References may be submitted in any consistent style, with author-year in-text citations. Reference list must be arranged alphabetically and then chronologically if needed, and entries must include author names, source title information, year, and volume or pagination where applicable.
Figures & Tables Figures must be uploaded as separate files, while tables must be submitted as editable text. Tables must be cited in the text, numbered consecutively, and include captions and notes below the table body, and Review Papers should include tables summarizing key findings unless justified otherwise.
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Discussion Papers

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 250 words.
Manuscript Manuscript must be divided into clearly defined sections using headings. Submission must include 1 to 7 English keywords, 3 to 5 highlights of no more than 85 characters each, and a declaration of generative AI use specifying the tool and reason if such tools were used in writing.
References References may be submitted in any consistent style but must use author-year in-text citations and an alphabetically ordered reference list with complete bibliographic details.
Figures & Tables Tables must be provided as editable text and figures must be uploaded as separate files alongside the manuscript. All tables and figures must be cited in the text, numbered consecutively, and include captions.
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Recent Publications

A homozygous GABRA2 variant associated with infantile spasms evolving to Lennox-Gastaut syndrome alters receptor gating

Jolien De Waele, Marcelo Diaz-Bustamante, Najat Aourz, Sara Cottyn, Gino De Smet, Robrecht Raedt, John M. Schreiber, William D. Gaillard, Dimitri De Bundel, Ilse Smolders, Frank Bosmans

10.1016/j.nbd.2026.107650
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Treatment-refractory autoimmune glial fibrillary acidic protein astrocytopathy: Clinical features, predictive models, therapy

Shifeng Zhang, Huilu Li, Haiyan Yao, Ting Li, M.M. Wendong Lai, M.M. Shiyu He, M.M. Peihao Lin, Jie Yang, Yaqing Shu, Dayang Hui, M.M. Li Huang, Cong Gao, Xiaorong Liu, Youming Long

10.1016/j.nbd.2026.107653
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Maternal delivery of a MuSK agonist antibody reveals a novel strategy for understanding and treating early-onset neuromuscular diseases

Julien Oury, Leah Santana, Karen Silence, Roeland Vanhauwaert, Steven J. Burden

10.1016/j.nbd.2026.107647
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D2 dopamine and CB2 cannabinoid receptor cooperation restores striatal LTP in an epilepsy model

Miriam Sciaccaluga, Laura Bellingacci, Valentina Imperatore, Anna Aurora Taddei, Alessandro Tozzi, Massimiliano Di Filippo, Marta Barzasi, Fabrizio Gardoni, Marina P. Sánchez, José M. Serratosa, Lucilla Parnetti, Andrea Mancini, Cinzia Costa

10.1016/j.nbd.2026.107648
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KIF1A c.773C > T impairs neural progenitor differentiation and axonal transport in association with dysregulated Wnt/β-catenin-BDNF signaling

Yong Liu, Jiayuan Wang, Ruonan Duan, Xiaoyi Wang, Jie Zhang, Mengru Li, Jian Sun, Yulin Zeng, Haopeng Kan, Tonghui Meng, Xinrui Liu, Yu Zhang, Jiexin Tang, Kexin Shi, Ziyu Wei, Yecheng Jin, Jiangxia Li, Xi Li, Qiji Liu, Jinlong Ma, Yuan Gao, Wenjie Sun

10.1016/j.nbd.2026.107645
View Publication

Frequently asked questions

How long does it take to publish?

1 day submission to first decision; 29 days submission to decision after review; 86 days submission to acceptance; 2 days acceptance to online publication.

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Is a cover letter required?

Review papers should state in the cover letter that the rules on AI were followed. A general cover letter requirement for all submissions is not stated.

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What are the publication costs?

Article Publishing Charge: USD 4060 excluding taxes for all articles.

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Research Topics

Neuroscience and Neuropharmacology Research Alzheimer's disease research and treatments Parkinson's Disease Mechanisms and Treatments Neuroinflammation and Neurodegeneration Mechanisms Genetic Neurodegenerative Diseases Neurological disorders and treatments Mitochondrial Function and Pathology Neurogenesis and neuroplasticity mechanisms Nerve injury and regeneration Amyotrophic Lateral Sclerosis Research Genetics and Neurodevelopmental Disorders Diverse Scientific and Economic Studies Epilepsy research and treatment Human auditory perception and evaluation Ion channel regulation and function Educational Robotics and Engineering Neurogenetic and Muscular Disorders Research Nuclear Receptors and Signaling Cholinesterase and Neurodegenerative Diseases Tryptophan and brain disorders Cellular transport and secretion Prion Diseases and Protein Misfolding RNA regulation and disease Neurological diseases and metabolism Lysosomal Storage Disorders Research

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