OA

Osteoarthritis And Cartilage

Osteoarthritis and Cartilage is the official journal of the Osteoarthritis Research Society International. It is an international, multidisciplinary journal that disseminates information for specialists and practitioners concerned with osteoarthritis and fosters cross-fertilization of findings from clinical and basic sciences including osteoarthritis, cartilage, molecular biology, clinical pharmacology, orthopaedics, rheumatology, physical medicine, biochemistry, epidemiology, and collagens.

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Impact Factor 9
Quartile Q1
Open Access Type Hybrid
ISSN 1063-4584
eISSN 1522-9653
Invitation Only No
Cost Range USD 4460 APC for open access articles; no open access publication fee for subscription articles.

Submission Instructions

Osteoarthritis And Cartilage accepts the following article types. Click on an article type to view submission instructions.

Invited Reviews

Cover Letter A cover letter must be appended to the manuscript.
Abstract An abstract is required in a separate file with the title page. Abstract must not exceed 350 words. Abstract must be structured. Abstract must include the headings Objective, Design, Results, and Conclusions.
Manuscript Methods must contain details relevant to the conduct and interpretation of the study. Three to six keywords must appear immediately after the abstract, and the manuscript must include author contribution declarations, a competing interest statement, and, if applicable, a Declaration of Generative AI and AI-assisted technologies in the writing process before the references.
References References must use numbered citations in square brackets in AMA style. References must be numbered in the order of appearance in the text and journal names must be abbreviated according to LTWA.
Figures & Tables Figures must not be included within the main text file and must be supplied as separate image files, while figure legends and tables must be placed on separate pages at the end of the manuscript. Figures and tables must be cited in the text in order of appearance and numbered using Arabic numerals, with table legends placed above each table and a legend provided for each illustration.
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Full Length Original Research Article

Cover Letter A cover letter must be appended to the manuscript.
Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be structured. Abstract must include the headings Objective, Design, Results, and Conclusions.
Manuscript Manuscript must not exceed 4000 words, excluding the title page, abstract, tables, figure legends, acknowledgements, contributions, and references. Manuscript must be organized in this order: Title page, Abstract, Introduction, Method, Results, Discussion, Acknowledgments, Author contributions, Role of the funding source, Conflict of interest, References, Figure legends, each individual Table, and each individual Figure. Immediately after the abstract, 3-6 keywords must be provided, and the manuscript must include author contributions, a role of the funding source section, a competing interest statement, and a Declaration of Generative AI and AI-assisted technologies in the writing process before the references if applicable.
References References must not exceed 50. References must use AMA style. References must be cited by number in square brackets and listed in numerical order of appearance, with journal names abbreviated according to LTWA.
Figures & Tables Figures and tables combined must not exceed 8. Figures must not be included within the main text file and must be supplied as separate image files, while figure legends must appear on a separate page at the end of the manuscript and tables must be submitted on separate pages. Figures and tables must be numbered in Arabic numerals, cited in the text in order of appearance, have suggested positions marked in the manuscript, and each illustration must have a legend with table legends placed above each table.
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Narrative Reviews

Cover Letter A cover letter must be appended to the manuscript.
Abstract A structured abstract is required. Abstract must not exceed 350 words. Abstract must be structured. Abstract must include the headings Objective, Design, Results, and Conclusions.
Manuscript Manuscript has a suggested limit of 4000 words, excluding the title page, abstract, tables, figure legends, acknowledgements, contributions, and references. Manuscript format should comply with the International Committee of Medical Journal Editors' Uniform Requirements for Manuscripts Submitted to Biomedical Journals. The manuscript must include 3-6 keywords immediately after the abstract, an authors' contributions declaration, a competing interest statement, and, if applicable, a 'Declaration of Generative AI and AI-assisted technologies in the writing process' before the references.
References References must not exceed 100. References must follow AMA style. References must be cited by number in square brackets and listed in numerical order of appearance, with journal names abbreviated according to LTWA.
Figures & Tables Tables and figures combined must not exceed 8. Figures must not be included within the main text file and must be supplied as separate image files, while tables must be appended to the manuscript. Figure legends must be included on a separate page at the end of the manuscript, each illustration must have a legend, suggested figure and table positions must be marked in the text, and figures and tables must be numbered in Arabic numerals.
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Systematic Reviews

Cover Letter A cover letter must be appended to the manuscript.
Abstract A structured abstract is required. Abstract must not exceed 350 words. Abstract must be structured. Abstract must include the headings Objective, Design, Results, and Conclusions.
Manuscript Manuscript has a suggested word count of 4000 words, excluding the title page, abstract, tables, figure legends, acknowledgements, contributions, and references. Immediately after the abstract, provide 3-6 keywords, and include author contributions, a competing interest statement, funding and sponsor role declarations, and if applicable a 'Declaration of Generative AI and AI-assisted technologies in the writing process' before the references.
References References must not exceed 100. References must follow American Medical Association Manual of Style, 8th edition. Cite references in the text using numbers in square brackets and list them in numerical order of first appearance with journal names abbreviated according to LTWA.
Figures & Tables Tables and figures combined must not exceed 8. Figures must not be included within the main text file and must be supplied as separate image files, while figure legends and tables are appended to the manuscript on separate pages. Mark the suggested positions of figures and tables in the text, cite them in order of appearance, use Arabic numbering, place table legends above each table, and provide a legend for each illustration.
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Meta-Analyses'

Cover Letter A cover letter must be appended to the manuscript.
Abstract A structured abstract is required. Abstract must not exceed 350 words. Abstract must be structured. Abstract sections must include Objective, Design, Results, and Conclusions.
Manuscript Suggested manuscript length is 4000 words, excluding the title page, abstract, tables, figure legends, acknowledgements, contributions, and references. Manuscript format should comply with the International Committee of Medical Journal Editors' Uniform Requirements for Manuscripts Submitted to Biomedical Journals. The manuscript must include 3-6 keywords immediately after the abstract, an authors' contributions declaration, a competing interest statement, and a Declaration of Generative AI and AI-assisted technologies in the writing process before the references if such tools were used.
References References must not exceed 100. References must follow AMA style. References must be cited by number in square brackets and listed in numerical order of appearance, with journal names abbreviated according to LTWA.
Figures & Tables Tables and figures combined must not exceed 8. Figures must not be included within the main text file and should be supplied as separate image files, while figure legends and tables must be placed on separate pages at the end of the manuscript. Suggested positions of figures and tables must be marked in the text, they must be cited in order of appearance, use Arabic numbering, and each figure and table must appear on a separate page with table legends above each table and a legend for each illustration.
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Letter To The Editor

Cover Letter A cover letter must be appended to the manuscript.
Abstract Abstract must not be included.
Manuscript Manuscript must not exceed 800 words. A declaration of generative AI and AI-assisted technologies in the writing process must be included before the references if such tools were used.
References References must not exceed 8. References must be cited numerically using square brackets. References must be numbered in the order of appearance and journal names must be abbreviated according to LTWA.
Figures & Tables Tables and figures must not be included.
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Brief Report Of Original Research

Cover Letter A cover letter must be appended to the manuscript.
Abstract An abstract is required in a separate file with the title page. Abstract must not exceed 250 words. Abstract must be structured. Abstract must include the headings Objective, Design, Results, and Conclusions.
Manuscript Main text must not exceed 2000 words, excluding the title page, abstract, tables, figure legends, acknowledgements, contributions, and references. Manuscript format should comply with the International Committee of Medical Journal Editors' Uniform Requirements for Manuscripts Submitted to Biomedical Journals. The manuscript must include 3-6 keywords after the abstract, author contribution declarations, a competing interest statement, funding and sponsor role disclosures, and an AI-use declaration when applicable.
References Manuscripts must not exceed 15 references. References must follow AMA style. References must be cited by number in square brackets and listed in numerical order of appearance, with journal names abbreviated according to LTWA.
Figures & Tables Manuscripts must not exceed 2 figures and/or tables. Figures must not be included within the main text file and must be supplied as separate image files, while tables must be appended to the manuscript on separate pages. Figure and table positions must be marked and cited in order of appearance, Arabic numbering must be used, each table must be on a separate page with its legend above it, and each figure must have a legend on a separate page at the end of the manuscript.
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Recent Publications

T2 and T1ρ Mapping Reveals Time-Dependent Cartilage Response to In-Scanner Cyclic Compression After ACL Reconstruction

Hongtian Zhu, Woowon Lee, Timothy W. Lowe, Emily Y. Miller, Nancy C. Emery, Jonathan T. Bravman, Eric C. McCarty, Rachel M. Frank, Corey P. Neu

10.1016/j.joca.2026.04.016
View Publication

The association of CT-detected intra-articular calcification with MRI-detected effusion-synovitis and Hoffa-synovitis in knee OA: The Multicenter Osteoarthritis study

Jean W. Liew, Mohamed Jarraya, Ali Guermazi, Nene C. Ukonu, Gabriela Rabasa, Robert Terkeltaub, David Felson, Michael Nevitt, Cora E. Lewis, James Torner, Tuhina Neogi

10.1016/j.joca.2026.04.017
View Publication

The prevalence of varus thrust: A systematic review and Meta-analysis

Haonan Shen, Nicole D'Souza, Claire E. Hille, Marnee J. McKay, Kun Hu, Zhiyong Wang, Milena Simic

10.1016/j.joca.2026.05.001
View Publication

Anti-Inflammatory and Anabolic Effects of Liraglutide on 3D Inflammatory Osteoarthritic Spheroid and Scaffold Models of Human Chondrocytes

Eda Ciftci, Sophie C. Eberlein, Sibylle Grad, Mauro Alini, Francis Berenbaum, Zhen Li

10.1016/j.joca.2026.04.018
View Publication

Transient Receptor Potential Melastatin 3 ion channel expressed in sensory neurons mediates osteoarthritis pain in mice

Robson da Costa, Suelen Pereira, Clive Gentry, Fabiana C. Dias, Bianca de Lima Almeida, Margot Maurer, Laura I. Primicheru, Lio Moreira, Stefanie Mannebach, Petra Weissgerber, Stephan E. Philipp, David A. Andersson, Stuart Bevan

10.1016/j.joca.2026.04.015
View Publication

Frequently asked questions

How long does it take to publish?

55 days from submission to decision after review; 142 days from submission to acceptance; 8 days from acceptance to online publication.

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Is a cover letter required?

A cover letter is required. It must state ethics approvals for research on humans or animals, provide a strong rationale for Mendelian Randomisation studies when applicable, explain instrumental variable assumptions when relevant, note fast track requests when applicable, and identify closely related papers or manuscripts submitted or published elsewhere in a note to the Editor.

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What are the publication costs?

Open access APC: USD 4460 excluding taxes for all articles. Subscription publication has no open access publication fee.

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Research Topics

Osteoarthritis Treatment and Mechanisms Total Knee Arthroplasty Outcomes Knee injuries and reconstruction techniques Inflammatory mediators and NSAID effects Rheumatoid Arthritis Research and Therapies Lower Extremity Biomechanics and Pathologies Bone and Joint Diseases Orthopaedic implants and arthroplasty Medical and Biological Sciences Musculoskeletal pain and rehabilitation Hip disorders and treatments Shoulder Injury and Treatment Tendon Structure and Treatment Musculoskeletal Disorders and Rehabilitation Orthopedic Infections and Treatments Proteoglycans and glycosaminoglycans research Orthopedic Surgery and Rehabilitation Musculoskeletal synovial abnormalities and treatments Pain Mechanisms and Treatments Bone Metabolism and Diseases Cytokine Signaling Pathways and Interactions Mesenchymal stem cell research Cancer-related molecular mechanisms research Spine and Intervertebral Disc Pathology Cell Adhesion Molecules Research