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Neurobiology of Pain

Neurobiology of Pain is an international journal for the publication of basic and translational research on the mechanisms of acute and chronic pain. It focuses on experimental studies of pain mechanisms from molecular and cellular levels to brain imaging and behaviour, and primarily publishes original basic and translational studies while also considering clinical studies that address mechanistic aspects of pain using experimental approaches in human subjects. The journal publishes original research, full and mini-reviews, brief reports, commentaries, special issues, and may consider negative or null data papers and replication studies important to the field of acute and chronic pain.

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Impact Factor 3.2
Quartile Q2
Open Access Type Open
eISSN 2452-073X
Invitation Only No
Cost Range Article Publishing Charge: USD 2770 excl. taxes for all articles.

Submission Instructions

Neurobiology of Pain accepts the following article types. Click on an article type to view submission instructions.

Research Articles

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 250 words. Abstract must be unstructured.
Manuscript Manuscript should be divided into clearly defined and numbered sections, with the abstract excluded from section numbering and acknowledgements placed in a separate section before the references. Submission must include 1 to 7 English keywords, 3 to 5 highlights submitted as a separate editable file, and a generative AI declaration in a new section placed before the references if such tools were used in manuscript preparation.
References Citations must use an author-date style. References may be in any consistent style at submission, but the list must be arranged alphabetically and then chronologically if needed and include complete bibliographic details.
Figures & Tables Figures and other artwork must be uploaded as separate files, while tables must be submitted as editable text. Tables must be editable text with captions and consecutive numbering, and all figures and tables must be cited in the manuscript text and numbered in order of appearance.
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Review Articles

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 250 words. Abstract must be unstructured.
Manuscript Manuscript should be divided into clearly defined and numbered sections, with the abstract excluded from section numbering and acknowledgements placed in a separate section before the references. The submission must include 1 to 7 keywords in English, 3 to 5 highlights submitted as a separate editable file, and a generative AI declaration in a new section placed before the references if such tools were used in manuscript preparation.
References References may be submitted in any consistent style, but in-text citations must use author names and year of publication. Reference list must include all cited works, be arranged alphabetically and then chronologically if needed, and include core bibliographic details for each entry.
Figures & Tables Figures must be supplied as separate files, while tables must be submitted as editable text and cited in the manuscript. Tables must be numbered consecutively and include captions, and all artwork must be numbered according to appearance and provided with captions.
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Mini-Review Articles

Cover Letter All authors must approve the submission, competing interests and funding must be declared, and any use of generative AI in manuscript preparation must be disclosed.
Abstract An abstract is required. Abstract must not exceed 250 words.
Manuscript The manuscript should be divided into clearly defined and numbered sections. The submission must include 1 to 7 keywords in English, 3 to 5 highlights as a separate editable file, and a generative AI declaration section placed before the references if AI tools were used.
References In-text citations must use author names and year of publication. References may be in any consistent style at submission, but the reference list must be arranged alphabetically and then chronologically if needed.
Figures & Tables Tables must be submitted as editable text and figures must be supplied as separate files along with the manuscript. All tables and figures must be cited in the text, numbered in order of appearance, and accompanied by captions.
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Short Communications

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 250 words.
Manuscript Manuscript must be no more than 3,000 words including figure legends but excluding references. Short Communications must present original experimental results and be complete in all respects. Manuscript must include 1 to 7 keywords in English, 3 to 5 highlights submitted as a separate editable file, and a generative AI declaration in a section placed before the references if such tools were used.
References Citations must use author names and year of publication. References may be submitted in any consistent style, but the reference list must be arranged alphabetically and then chronologically if necessary and include complete bibliographic details.
Figures & Tables Short Communications may include no more than 1 figure and 1 table or 2 of either. Figures must be supplied as separate files along with the manuscript, while tables are addressed only as editable text. Tables must be editable text with captions and consecutive numbering, and all figures and tables must be cited in the manuscript text.
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Negative/Null Data Papers

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 250 words. Abstract must be unstructured.
Manuscript Manuscript should be divided into clearly defined and numbered sections, with the abstract excluded from section numbering. The submission must include 1 to 7 English keywords, highlights of 3 to 5 bullet points submitted as a separate editable file, acknowledgements in a separate section before the references, CRediT author contributions, and a generative AI declaration in a section placed before the references if AI tools were used.
References Citations must use an author-date style. References may be in any consistent style at submission, but the reference list must be arranged alphabetically and then chronologically if needed and include complete bibliographic details.
Figures & Tables Tables must be submitted as editable text and figures must be supplied as separate files along with the manuscript. Tables and figures must be cited in the text, numbered consecutively in order of appearance, and accompanied by captions.
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Replication Studies

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 250 words. Abstract must be unstructured.
Manuscript Manuscript should be divided into clearly defined and numbered sections, with the abstract excluded from section numbering and acknowledgements placed in a separate section before the references. The submission must include 1 to 7 English keywords, 3 to 5 highlights submitted as a separate editable file, and a generative AI declaration in a new section placed before the references if such tools were used.
References References may use any consistent style at submission, with in-text citations in author-date format. Reference entries must include core bibliographic details, the reference list must be arranged alphabetically then chronologically if needed, and journal names must be abbreviated according to the List of Title Word Abbreviations.
Figures & Tables Tables must be included as editable text and figures must be uploaded as separate files along with the manuscript. Tables and figures must be cited in the text, numbered in order of appearance, and accompanied by captions.
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Recent Publications

Pain-Induced changes in corticospinal excitability are associated with adaptive changes in muscle coordination

Arnaud Duport, Gaspard Diotalevi, Pierre Morel, Flore Le Blanc, Guillaume Léonard, Hervé Devanne

10.1016/j.ynpai.2026.100212
View Publication

White matter differences in motor and affective-motivational networks of pain-indifferent carriers of the R221W mutation

Arnas Tamasauskas, Irene Perini, Jan Minde, Simon S. Keller, Nicholas Fallon, Bernhard Frank, India Morrison, Andrew Marshall

10.1016/j.ynpai.2026.100211
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Biophysical dissection of nociceptor hyperexcitability caused by a Nav1.8 gain-of-function mutation linked to severe pain

Dmytro V. Vasylyev, Peng Zhao, Stephen G. Waxman

10.1016/j.ynpai.2026.100214
View Publication

Sex differences in nerve injury-induced neuropathic pain via REST in primary sensory neurons

Aadhya Tiwari, Ashok Subedi, Asieh Etemad, Yuying Huang, Biji Chatterjee, Samantha M. McLeod, Yungang Lu, Eun-Myung Mary Song, DiAngelo Gonzalez, Sanjay K. Singh, J. Jack Lee, Hui-Lin Pan, Sadhan Majumder

10.1016/j.ynpai.2026.100213
View Publication

Relationship between brain metabolites and chronic pain mechanisms in knee osteoarthritis pre- and post-total knee replacement

Samantha A Leech, Marilena M DeMayo, Tiffany K Bell, Mataea AL Armstrong, Claudia M Campbell, Chel Hee Lee, Eldridge Batuyong, Geoff Schneider, Neil J White, Richard EA Walker, Kayla Millar, Charley Hasselaar, Richard Ng, Sarah L Manske, Ashley D Harris

10.1016/j.ynpai.2026.100215
View Publication

Frequently asked questions

How long does it take to publish?

1 day submission to first decision; 31 days submission to decision after review; 94 days submission to acceptance; 7 days acceptance to online publication.

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What are the publication costs?

Article Publishing Charge: USD 2770 excl. taxes for all articles.

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Research Topics

Pain Mechanisms and Treatments Musculoskeletal pain and rehabilitation Neuropeptides and Animal Physiology Migraine and Headache Studies Ion channel regulation and function Fibromyalgia and Chronic Fatigue Syndrome Research Neuroscience and Neuropharmacology Research Nerve injury and regeneration Pain Management and Placebo Effect Pediatric Pain Management Techniques Ion Channels and Receptors Neuroscience of respiration and sleep Stress Responses and Cortisol Heart Rate Variability and Autonomic Control Pain Management and Treatment Neurotransmitter Receptor Influence on Behavior Pain Management and Opioid Use Botulinum Toxin and Related Neurological Disorders Cancer Treatment and Pharmacology Gut microbiota and health Osteoarthritis Treatment and Mechanisms Functional Brain Connectivity Studies Exercise and Physiological Responses Trigeminal Neuralgia and Treatments Cannabis and Cannabinoid Research