Overview Submission Instructions Recent Publications Frequently Asked Questions Research Topics

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Pain and Therapy

Pain and Therapy is an international, open access, peer-reviewed rapid publication journal focused on high-quality clinical, observational, real-world, and health outcomes research on the discovery, development, and use of pain therapies and pain-related devices. It also encourages studies related to diagnosis, pharmacoeconomics, public health, quality of life, and patient care, management, and education.

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Subject Clinical Neurology

Impact Factor 3.3

Quartile Q2

Open Access Type Open

ISSN 2193-8237

eISSN 2193-651X

Invitation Only No

Cost Range £5120.00 GBP / $7675.00 USD / €5950.00 EUR APC; VAT or local taxes may apply.

Submission Instructions

Pain and Therapy accepts the following article types. Click on an article type to view submission instructions.

Original Research

Cover Letter Cover Letter requirements are not specified.

Abstract An abstract is required. Abstract must be no more than 300 words. Abstract must be structured. Abstract headings must be Introduction, Methods, Results, and Conclusion.

Manuscript Original Research articles should be around 4000 words but are not limited to that length. Main text should use the headings Introduction, Methods, Results, and Conclusion. Manuscript must include 3 to 10 keywords, 4-5 single-sentence key summary points using 'Why carry out this study?' and 'What was learned from the study?', an author contribution statement, a Declarations section before the references, an acknowledgements section before the references, and documentation of any Large Language Model use in the Methods section.

References References must use the Vancouver system. In-text citations must be Arabic numerals in square brackets, references must be listed in the order cited, and references with up to six authors list all authors while those with more than six list the first three followed by et al.

Figures & Tables Tables must be included in the manuscript, figure legends must appear in the manuscript after the references, and each figure must be submitted as a separate file. Figures and tables must be cited in the text and numbered consecutively, figure parts should use lower-case roman letters, tables must have a concise title and be provided in an editable format, and figure legends must explain all abbreviations, colours, and symbols.

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Reviews

Cover Letter Cover Letter requirements are not specified.

Abstract An abstract is required for Reviews and it does not need to be structured. The abstract must be no more than 300 words. The abstract may be unstructured for Reviews.

Manuscript There is no word limit for Reviews. The title must indicate the format of the Review. The manuscript must include 4–5 single-sentence key summary points, a Declarations section before the references, an author contribution statement describing who had the idea for the article, who performed the literature search and data analysis, and who drafted and/or critically revised the work, and, if applicable, the sentence stating that the article is based on previously conducted studies and contains no new studies with human participants or animals performed by the authors.

References References must use the Vancouver system. References must include only works cited in the text, list up to six authors in full or the first three followed by et al. if there are more than six, use Arabic numerals in square brackets for in-text citations, and be ordered to match the citation sequence in the text.

Figures & Tables Tables and figure legends must be included in the manuscript, and each figure must be submitted as a separate file. Figures and tables must be cited and numbered consecutively in the text, and tables must be provided in an editable format rather than as images.

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Narrative Review

Cover Letter Cover Letter requirements are not specified.

Abstract An abstract is required for Narrative Reviews. Abstract must be no more than 300 words. Review abstracts do not need to be structured.

Manuscript There is no word limit for Reviews. The title must indicate the format of the Review. The manuscript must include 4-5 single-sentence key summary points, a disclosure statement, a Declarations section before the references, an author contribution statement indicating who conceived the article, performed the literature search and data analysis, and drafted and or critically revised the work, and for articles without author-conducted human or animal studies the exact sentence stating that the article is based on previously conducted studies and contains no new studies with human participants or animals performed by the authors.

References References must use the Vancouver system. Only works cited in the text should appear in the reference list, references should be numbered in text with Arabic numerals in square brackets in sequential order, and references with up to six authors should list all authors while those with more than six should list the first three followed by et al.

Figures & Tables Tables and figure legends must be included in the manuscript file, while each figure must be submitted as a separate file. All figures and tables must be cited in the text and numbered consecutively, with figure parts identified by lower-case roman letters and tables supplied in an editable format.

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Systemic Review

Cover Letter Cover Letter requirements are not specified.

Abstract An abstract is required. Abstract must be no more than 300 words. Abstract does not need to be structured.

Manuscript There is no word limit for Systemic Review articles. Title must indicate the review format. Manuscript must include 3 to 10 keywords, 4-5 single-sentence key summary points, a Declarations section before the references, an author contribution statement including who conceived the article, performed the literature search and data analysis, and drafted or critically revised the work, documentation of any Large Language Model use in the Methods or another suitable section, and the specified no-new-studies statement when applicable.

References References must use the Vancouver system. In-text citations must be Arabic numerals in square brackets, references must be listed in citation order, and references with up to six authors list all authors while those with more than six list the first three followed by et al.

Figures & Tables Tables must be included in the manuscript, figure legends must appear in the manuscript after the references, and each figure must be submitted as a separate file. Figures and tables must be cited in the text and numbered consecutively, figure parts should use lower-case roman letters, tables must have a concise title, and tables must be provided in an editable format rather than as images.

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Brief Reports

Cover Letter The cover letter must mention any unpublished material included in the manuscript and provide transparency on any re-use of material.

Abstract An abstract is required. The abstract must be no more than 300 words. The abstract must be structured. The abstract should use the headings Introduction, Methods, Results, and Conclusion.

Manuscript Brief Reports should be around 2000-3000 words. The main text should use the headings Introduction, Methods, Results, and Conclusion. The manuscript must include 3 to 10 keywords, 4-5 single-sentence bullet-point key summary points below the abstract, an author contribution statement, a Declarations section before the references, and documentation of any Large Language Model use in the Methods section or another suitable section if no Methods section is available.

References References must use the Vancouver system. In-text citations must be Arabic numerals in square brackets, the reference list must follow citation order, and references with up to six authors list all authors while those with more than six list the first three followed by et al.

Figures & Tables Tables and figure legends must be included in the manuscript, while each figure must be submitted as a separate file. Figures and tables must be cited in the text and numbered consecutively, figure parts should use lower-case roman letters, tables must be editable rather than images, and legends or titles are required.

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Case Series

Cover Letter Cover Letter requirements are not specified.

Abstract An abstract is required. Abstract must be up to 300 words.

Manuscript Case Series should be around 3000 words. Case Series should follow the structure Abstract; Introduction; Case presentations; Discussion; Conclusion(s); Acknowledgements; References. The manuscript must include 4-5 single-sentence key summary points below the abstract stating what is unique about the case and what it adds to the current literature, an author contribution statement, a Declarations section before the references, and 3 to 10 keywords.

Figures & Tables Tables must be included in the manuscript, figure legends must appear in the manuscript after the references, and each figure must be submitted as a separate file. Figures and tables must be cited in the text and numbered consecutively, figure parts should use lower-case roman letters, tables must be editable rather than images, and figure legends must explain all abbreviations, colours, and symbols.

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Case Report

Cover Letter Cover Letter requirements are not specified.

Abstract An abstract is required. Abstract must be up to 300 words.

Manuscript Case Reports should be around 2000 words. The manuscript must include 3 to 10 keywords, 4 to 5 single-sentence key summary points stating what is unique about the case and what it adds to the current literature, an acknowledgements section, and a Declarations section before the references.

References References must use the Vancouver system. In-text citations must be Arabic numerals in square brackets, the reference list must follow citation order, and references with more than six authors must list the first three followed by et al.

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Guidelines

Cover Letter Cover letter must mention any unpublished material included in the manuscript and provide transparency on any re-use of material.

Abstract Abstract is required. Abstract must be no more than 300 words.

Manuscript Guidelines should be around 10,000–15,000 words. Manuscript must include 3 to 10 keywords, 4–5 single-sentence bullet-point key summary points below the abstract, an author contribution statement, a Declarations section before the references, an Acknowledgements section, and the disclaimer "Springer Healthcare is not responsible for the validity of guidelines it publishes."

References References must use the Vancouver system. In-text citations must be Arabic numerals in square brackets, references must be listed in citation order, and references with more than six authors must list the first three followed by et al.

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Letter To The Editor

Cover Letter Cover letter should mention any unpublished material included in the manuscript and provide transparency on any re-use of material.

Abstract Abstract is not mandatory for this article type. If included, the abstract may be up to 300 words.

Manuscript Letter to the Editor should be around, but is not limited to, 1000 words. Letter to the Editor should comment on a recently published article in the journal. Manuscript must include a Declarations section before the references, an author contribution statement, 3 to 10 keywords, and key summary points are not mandatory.

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Recent Publications

Effect of Transcranial Magnetic Stimulation in Patients with Postherpetic Neuralgia and Comorbid Depression: A Randomized Controlled Trial

Huichan Xu, Junpeng Yuan, Chen Zhao, Liqun Huang, Panqi Wang, Youjia Yu, Xiaohong Jin

10.1007/s40122-026-00840-z

View Publication

Results from TRIUMPH [EUROPE], a Real-World Observational Study on the 3-Month Effectiveness of Galcanezumab Versus Traditional Oral Migraine Preventive Medications

Cristina Tassorelli, Diego Novick, Saygin Gonderten, Maurice Vincent, Rebecca L. Robinson, Georgia Martimianaki, Patricia Pozo Rosich

10.1007/s40122-026-00839-6

View Publication

Correction: Next‑Generation SCS Programming Platform: Enhancing ECAP Fidelity and Objectivity to Improve Patient Experience

Daniel J. Parker, Ajay B. Antony, Gregory L. Smith, Johnathan H. Goree, Marc A. Russo, Erika A. Petersen, Chau M. Vu, Paul Verrills, Christopher Gilmore, Leonardo Kapural, Darayus Nanavati, Dean M. Karantonis, Jason E. Pope

10.1007/s40122-026-00838-7

View Publication

Supraspinal Correlates of Patients with Chronic Pain Under Burst Spinal Cord Stimulation: A Proof-of-Concept Functional MRI Study

Steffen Brenner, Achim Schilling, Patrick Krauss, Sherif Mohamed, Julia Fauth, Zohair Niroomand, Thomas Mehari Kinfe

10.1007/s40122-026-00841-y

View Publication

Comparative Cost-Utility and Clinical Efficacy of 5-HT3 Receptor Antagonists in Sufentanil-Based PCIA: A Propensity Score-Matched Analysis

Youmei Wu, Yingchao Ye, Han Gong, Fangfang Xia

10.1007/s40122-026-00847-6

View Publication

Frequently asked questions

How long does it take to publish?

The journal aims for a 2-week peer review, 3-4 weeks from acceptance to online publication, and a median submission-to-first-decision time of 2 days.

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Is a cover letter required?

A cover letter may include information on unpublished material and transparency on re-use of material, and authors can suggest peer reviewers in the cover letter.

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What are the publication costs?

The current APC is £5120.00 GBP / $7675.00 USD / €5950.00 EUR for each accepted article; VAT or local taxes may apply.

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Research Topics

Anesthesia and Pain Management Pain Management and Opioid Use Pain Mechanisms and Treatments Musculoskeletal pain and rehabilitation Spine and Intervertebral Disc Pathology Migraine and Headache Studies Pain Management and Treatment Opioid Use Disorder Treatment Pediatric Pain Management Techniques Nausea and vomiting management Myofascial pain diagnosis and treatment Trigeminal Neuralgia and Treatments Cancer, Stress, Anesthesia, and Immune Response Anesthesia and Sedative Agents Enhanced Recovery After Surgery Fibromyalgia and Chronic Fatigue Syndrome Research Neurological Complications and Syndromes Pain Management and Placebo Effect Herpesvirus Infections and Treatments Inflammatory mediators and NSAID effects Shoulder Injury and Treatment Cardiac, Anesthesia and Surgical Outcomes Traumatic Brain Injury Research Botulinum Toxin and Related Neurological Disorders Cervical and Thoracic Myelopathy

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