SP

Skin Pharmacology and Physiology

Skin Pharmacology and Physiology is a journal of pharmacological and biophysical research focused on topical therapies, original papers, and systematic reviews in pharmacological aspects of the skin and skin physiology. It invites work on epidermal barrier function, exogenous influences on skin functions, non-invasive studies of skin physiology, and regulatory pathways involved in skin penetration of topical formulations through in vivo and in vitro models, as well as systemic treatment studies on epidermal functions, innovative methodology, clinically relevant problems, and cosmetic studies with relevant effects on skin physiology and appropriate controls.

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Subject Dermatology, Pharmacology & Pharmacy
Impact Factor 3.2
Quartile Q1
Open Access Type Closed
ISSN 1660-5527
eISSN 1660-5535
Invitation Only No
Cost Range Subscription pricing is listed by year, region, and access type; for 2026 personal online access is EUR 480.00, CHF 480.00, or USD 533.00 per year, and 2026 institutional online access is EUR 2340.00, CHF 2340.00, or USD 2600.00 per year.

Submission Instructions

Skin Pharmacology and Physiology accepts the following article types. Click on an article type to view submission instructions.

Research Article

Cover Letter Cover letter is required. Cover letter must describe the knowledge gap addressed, explain the research significance and implications, and state how the manuscript fits the journal scope.
Abstract Abstract is required. Abstract must be structured. Abstract must use the headings Introduction, Methods, Results, and Conclusion and must not include bibliographic references or references to figures or tables.
Manuscript Research Articles are typically 5000 words in length. Manuscript must include the sections Introduction, Methods, Results, and Discussion. Manuscript must include 3–5 keywords, a statements section before the references containing Statement of Ethics, Conflict of Interest Statement, Funding Sources, Author Contributions, and Data Availability Statement, and any use of generative AI must be declared in the Methods section.
References References must be cited sequentially in the text using Arabic numerals in square brackets and listed numerically in citation order with up to 6 authors before adding et al.
Figures & Tables Research Articles typically include 4 to 8 tables and figures. Manuscript text, each table, and each figure must be submitted as separate files, with figure legends included at the end of the manuscript text. One file must be submitted per figure, including all panels, and tables must be editable Word files rather than images.
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Review Article

Cover Letter Cover letter is required. Cover letter must describe the knowledge gap addressed, discuss the research implications and significance, outline fit with the journal scope, and identify any special issue or invited collection where applicable.
Abstract Abstract is required. Abstract must be structured using the headings Background, Summary, and Key Messages. Abstract must include the headings Background, Summary, and Key Messages.
Manuscript Review Articles are typically 5000 words in length. Review Article must include a critical discussion of reported data and a clear conclusion with potential impacts on the standard of care. Manuscript must include 3–5 keywords and a statements section before the references containing Statement of Ethics, Conflict of Interest Statement, Funding Sources, Author Contributions, and Data Availability Statement, and any use of generative AI must be declared in the Acknowledgements if no Methods section is included.
References References must be cited sequentially in the text using Arabic numerals in square brackets and listed numerically in citation order with up to 6 authors before adding et al.
Figures & Tables Review Articles typically include 4 to 8 tables and figures. Each table and each figure must be submitted as a separate file, with figure legends placed at the end of the article after the reference list. Review Article abstracts must not include references to figures or tables.
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Systematic Review

Cover Letter Cover letter is required and must describe the knowledge gap addressed, the research implications and significance, and how the manuscript fits the journal scope. Cover letter must describe the knowledge gap addressed, discuss the implications and significance of the research, and explain how the manuscript fits within the journal scope.
Abstract Systematic Reviews must include a short abstract. Abstract must be structured. Abstract must use the headings Introduction, Methods, Results, and Conclusion.
Manuscript Systematic Reviews are typically 5000 words in length. Manuscript should be presented in Introduction, Methods, Results, Discussion format, with an optional final conclusion. Manuscript must include 3–5 keywords, the required statements section before the references, and any use of generative AI must be declared in the Methods section.
References References must be cited sequentially in the text using Arabic numerals in square brackets and listed numerically in citation order with up to 6 authors before adding et al.
Figures & Tables Systematic Reviews typically include 4 to 8 tables and figures. Each table and each figure must be submitted as separate files, with figure legends included in the manuscript text at the end of the article after the reference list. Abstract must not include references to figures or tables.
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Brief Report

Cover Letter Cover letter is required. Cover letter must describe the knowledge gap addressed, discuss the research significance and implications, and explain how the manuscript fits the journal scope.
Abstract A short abstract is required. Abstract must be structured. Abstract must use the headings Introduction, Methods, Results, and Conclusion.
Manuscript Manuscript is typically 3000 words in length. Manuscript should follow the same structure as a full-length research article and include Introduction, Methods, Results, and Discussion sections. Manuscript must include 3 to 5 keywords, the required statements after the main body and before the references, and any use of generative AI must be declared in the Methods section or in the Acknowledgements if no Methods section is present.
References Citations must use sequential Arabic numerals in square brackets. Reference list must include only cited publications, be arranged numerically in citation order, list up to 6 authors before using et al., and present authors as surnames followed by initials.
Figures & Tables Brief Reports may include up to 3 tables and figures. Figures and tables must be uploaded as separate items in their original file format rather than embedded in the manuscript. Figure legends must be provided at the end of the article after the references and figures cited in brackets must appear as Fig. followed by the number.
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Letter

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Letters are typically 1000 words in length. Letters must contain the required statements after the main body of the text and before the reference list and should not include original data. Letters must include 3–5 keywords and the manuscript must contain Conflict of Interest Statement, Funding Sources, and Author Contributions sections, with any generative AI use declared in the Acknowledgements section if no Methods section is included.
References References must be cited sequentially in the text using Arabic numerals in square brackets and listed numerically in the order cited with only cited publications included, listing up to 6 authors before adding "et al." for additional authors.
Figures & Tables Letters may include up to 3 tables and figures. Figures and tables must be uploaded as separate items, with one file per figure and figure legends placed at the end of the article after the reference list. Figure legends must use the format "Fig. 1." or "Fig. 1. a," and figures must be referred to as "Figure" in running text and as "Fig." with the number in round brackets.
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Recent Publications

Thiophene-Benzimidazole Conjugates Attenuate IL-33-induced Inflammation in Human Mast Cell Line and in ex vivo Human Skin Organ Cultures

Raanan Gvirtz, Shirin Kahremany, Lena Trifonov, Sagiv Weintraub, Edward E Korshin, Eldad Silberstein, Nataliia Shtil, Mykhailo Kompanets, Tomer Ayzenberg, Navit Ogen-Shtern, Guy Cohen, Arie Gruzman

10.1159/spp/aetag017
View Publication

Early-Stage Derisking of a Topical JAK Inhibitor Candidate in Healthy Human Skin Explants: Dermal Stability and Pharmacokinetics

Thomas Birngruber, Katrin Tiffner, Frank Sinner, Simon Schwingenschuh, Sylvia Furst, Stephan Bielfeldt, Brigitte Stephan

10.1159/spp/aetag018
View Publication

Effect of a Ceramide NP-Containing Moisturizer on Skin Barrier Function in Adults with Atopic Dermatitis: A Randomized, Double-Blind, Placebo-Controlled Study

Chaoying Gu, JIAYI YING, Huibin Yin, Chunyun Huang, Leihong Xiang

10.1159/spp/aetag011
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Activation of SIRT6 Using a Hydrolyzed Yeast Protein Extract to Enhance Skin Longevity by Targeting Multiple Hallmarks of Aging

Kelly Dong, Antonella Rella, Earl C Goyarts, Jacqueline Trivero, Nadine Pernodet, Rishabh Kala

10.1159/spp/aetag015
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Effects of extreme environmental conditions on the skin barrier: a pilot study from the “Under The Pole” project with spectral and biometric measurements

Aline RIGAL-DACHAUD, Rime Michael-Jubeli, Alex NKENGNE, Katell VIE, Arlette BAILLET-GUFFROY, Armelle BIGOURET, Ali Tfayli

10.1159/spp/aetag004
View Publication

Frequently asked questions

How long does it take to publish?

Accepted papers are published online within a few days of acceptance in Early View. Proof corrections are requested within 48 hours. Articles are published online ahead of print shortly after author approval to publish.

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Is a cover letter required?

A cover letter is required and should describe the gap in knowledge addressed by the manuscript, its implications and significance, how it fits the journal’s scope, and the manuscript’s unique contributions. Special issue or article collection submissions should name the collection and identify the inviter where applicable.

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What are the publication costs?

Subscription pricing is listed by year, region, and access type; for 2026 personal online access is EUR 480.00, CHF 480.00, or USD 533.00 per year, and 2026 institutional online access is EUR 2340.00, CHF 2340.00, or USD 2600.00 per year.

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Research Topics

Advancements in Transdermal Drug Delivery Dermatology and Skin Diseases Skin Protection and Aging Diverse Scientific and Economic Studies Human auditory perception and evaluation Contact Dermatitis and Allergies Wound Healing and Treatments Acne and Rosacea Treatments and Effects Bee Products Chemical Analysis Physics and Engineering Research Articles Neonatal skin health care melanin and skin pigmentation Psoriasis: Treatment and Pathogenesis Hair Growth and Disorders Allergic Rhinitis and Sensitization Dermatologic Treatments and Research Educational Robotics and Engineering Antioxidant Activity and Oxidative Stress Skin and Cellular Biology Research Essential Oils and Antimicrobial Activity Nail Diseases and Treatments Legal Cases and Commentary Advanced Drug Delivery Systems Retinoids in leukemia and cellular processes Photodynamic Therapy Research Studies

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