AJ

American Journal of Nephrology

American Journal of Nephrology is a peer-reviewed international journal focused on timely topics in basic science and clinical research in nephrology. It publishes original reports spanning clinical, basic, and outcomes research, in-depth topic reviews selected by the editor and associate editors, and invited debates on hot topics determined by the editorial board.

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Impact Factor 3.2
Quartile Q1
Open Access Type Closed
ISSN 0250-8095
eISSN 1421-9670
Invitation Only No
Cost Range Institutional online access: CHF 6726.00/year, EUR 6726.00/year, or USD 7473.00/year for 2026; personal online access: CHF 1345.00/year, EUR 1345.00/year, or USD 1494.00/year for 2026. Prices exclude VAT and local sales tax.

Submission Instructions

American Journal of Nephrology accepts the following article types. Click on an article type to view submission instructions.

In-Depth Topic Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required for In-Depth Topic Reviews. The abstract must be structured. The abstract must be divided into Background, Summary, and Key Messages.
Manuscript The manuscript must contain a statements section after the main body and before the references including Acknowledgement, Conflict of Interest Statement, Funding Sources, and Author Contributions, and any use of generative AI must be declared in the Methods or Acknowledgements section as applicable.
References References must be cited sequentially in square brackets and listed numerically in citation order, with up to 6 authors named before adding “et al.” for additional authors.
Figures & Tables Each table and each figure must be uploaded as a separate file, with figure legends placed at the end of the manuscript text.
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Research Article

Cover Letter A cover letter is required. Cover letter must describe the knowledge gap addressed, discuss the research significance and implications, explain fit with the journal scope, and emphasize the manuscript’s unique contribution.
Abstract A short abstract is required. Abstract must be structured. Abstract must use the headings Introduction, Methods, Results, and Conclusion.
Manuscript Research Articles are typically 5000 words in length. Manuscript must include Introduction, Methods, Results, and Discussion sections, with required statements placed after the main text and before the references. Manuscript must include 3–5 keywords and statements sections including Conflict of Interest, Funding Sources, Author Contributions, Data Availability, and a declaration of any generative AI use.
References Citations must use sequential Arabic numerals in square brackets. Reference list must include only cited publications, be arranged numerically in citation order, and list up to 6 authors before adding “et al.”.
Figures & Tables Research Articles typically include 4 to 8 tables and figures. Figures and tables must be uploaded as separate items in their original file format, and figure legends must appear at the end of the manuscript after the references. Figure legends must be formatted as “Fig. 1.” followed by the legend text.
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Review Article

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required. Abstract must be structured with the subheadings Background, Summary, and Key Messages. Abstract must use the headings Background, Summary, and Key Messages.
Manuscript Review Articles are typically 5000 words in length. Review Articles must include a critical discussion of the reported data and a clear conclusion with potential impacts on the standard of care. Manuscript must include 3–5 keywords and the required statements section, and any use of generative AI must be declared in the Methods section or in the Acknowledgements section if there is no Methods section.
References References must be cited sequentially in square brackets and listed numerically in citation order, with up to 6 authors named before “et al.” is used.
Figures & Tables Review Articles typically include 4 to 8 tables and figures. Each table and each figure must be submitted as a separate file, with figure legends included at the end of the manuscript text.
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Systematic Review

Cover Letter Cover Letter requirements are not specified.
Abstract Systematic Reviews must include a short abstract. The abstract must be structured. The abstract must use the headings Introduction, Methods, Results, and Conclusion.
Manuscript Systematic Reviews are typically 5000 words in length. Systematic Reviews should be presented in the Introduction, Methods, Results, Discussion format. The manuscript must include 3–5 keywords and statements after the main body text and before the reference list, and any use of generative AI-based tools must be declared in the Methods section or in the Acknowledgements section if there is no Methods section.
References References must be cited sequentially in the text using Arabic numerals in square brackets and the reference list must include only cited publications arranged numerically in order of citation, listing up to 6 authors before adding et al. if there are more than 6.
Figures & Tables Systematic Reviews typically include 4 to 8 tables and figures. Figures and tables must be uploaded as separate items in their original file format, and figure legends must be included at the end of the manuscript text after the reference list. Figure legends must use the format "Fig. 1." or "Fig. 1. a".
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Novel Research Findings

Cover Letter Cover letter is required. Cover letter must describe the knowledge gap addressed, explain the implications and significance of the research, outline fit with the journal scope, and emphasize the manuscript’s unique contributions.
Abstract Abstract is required. Abstract must not exceed 150 words. Abstract must be unstructured and presented in a single paragraph.
Manuscript Manuscript must not exceed 2500 words. Manuscript must include a statements section after the main text and before the references. Manuscript must include 3 to 5 keywords and the statements Acknowledgement, Conflict of Interest Statement, Funding Sources, and Author Contributions, and any use of generative AI must be declared in the Methods or Acknowledgements.
References References must not exceed 15. References must be cited sequentially in square brackets and listed numerically in citation order with up to 6 authors before “et al.”.
Figures & Tables Submission may include a maximum of one figure and one table. Figures and tables must be uploaded as separate files, with figure legends included in the manuscript text. Tables must be editable files rather than images, and each figure must be submitted as a single file containing all panels.
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Brief Report

Cover Letter A cover letter is required. Cover letter must describe the knowledge gap addressed, discuss the research implications and significance, explain the manuscript’s fit with the journal’s scope, emphasize its unique contribution, and name any relevant special issue or article collection invitation.
Abstract A short abstract is required. Abstract must be structured. Abstract must use the headings Introduction, Methods, Results, and Conclusion.
Manuscript Manuscript is typically 3000 words in length. Manuscript must follow the same structure as a full-length Research Article and include Introduction, Methods, Results, and Discussion sections. Manuscript must include 3–5 keywords and contain Acknowledgement, Conflict of Interest Statement, Funding Sources, Author Contributions, and Data Availability Statement after the main text and before the references, with any generative AI use declared in Methods or Acknowledgements.
References Citations must appear as sequential Arabic numerals in square brackets, and the reference list must include only cited works arranged numerically in citation order with up to 6 authors listed before using “et al.”.
Figures & Tables Brief Reports may include up to 3 tables and figures. Figures and tables must be uploaded as separate items in their original file format, and figure legends must appear at the end of the manuscript after the references. Figure legends must use the format “Fig. 1.”, figures cited in text must appear as “Figure” outside parentheses and “Fig.” inside parentheses, and tables must be editable files rather than images.
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Guidelines

Cover Letter Cover letter is required. Cover letter must describe the knowledge gap addressed, the implications and significance of the work, how it fits the journal scope, and its unique contributions, and should identify any special issue or invited collection submission if applicable.
Abstract Abstract is required. Abstract must be unstructured and presented as a single paragraph.
Manuscript Guidelines are typically 5000 words in length. Guidelines should describe the clinical problem, explain how the statement was generated, review the supporting evidence, and include the practice statement itself. Manuscript must include 3 to 5 keywords on the title page, the statements section before the references with Acknowledgement, Conflict of Interest Statement, Funding Sources, and Author Contributions, and any use of generative AI must be declared in the Methods or Acknowledgements section.
References References must be cited sequentially in square brackets and listed numerically in citation order, with up to 6 authors named before adding et al.
Figures & Tables Guidelines may include up to 3 tables and figures. Each table and each figure must be uploaded as a separate file, with figure legends placed at the end of the manuscript text after the references. Tables must be editable Word files rather than images, and multi-panel figures must be submitted as one file containing all panels arranged as they should appear.
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Letter

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Letters are typically 1000 words in length. Letters should not include original data. Letters must include a short title to be used as the running head and provide 3–5 keywords highlighting the most important points of the paper.
References References must be cited sequentially in the text using Arabic numerals in square brackets and listed numerically in citation order with up to 6 authors before “et al.”.
Figures & Tables Letters may include up to 3 tables and figures. Each table and each figure must be submitted as a separate file, with figure legends included at the end of the manuscript text.
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Recent Publications

Beyond the Amount: The Selectivity of Proteinuria and Risk of Graft Failure in Kidney Transplant Recipients

Firas F. Alkaff, Wendy Dam, Jenny E. Kootstra-Ros, Eva Corpeleijn, Moh R. Daha, Martin H. de Borst, Jacob van den Born, Stephan J.L. Bakker, Stefan P. Berger

10.1159/000552866
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Associations of body composition biomarkers with survival, cardiovascular events and progression in persons with chronic kidney disease: insights from Renal Risk in Derby Study

Ashveer Randhay, Nicholas M. Selby, Maarten W. Taal, Mohamed Tarek Eldehni

10.1159/000552844
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Predictors of variability in urine albumin to creatinine ratio in the general U.S. adult population

Sophie E. Claudel, Sushrut S. Waikar, Insa M. Schmidt, Ashish Verma

10.1159/000552774
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Forecasting Urgent Dialysis Needs: From Predictive Accuracy to Clinical Actionability

Fariha Shahid Tanveer, Muhammad Hassan Saeed

10.1159/000551551
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Effects of Sacubitril/Valsartan vs Irbesartan on Urine Tubular Biomarkers in CKD: Findings from the UK HARP-III Trial

Michelle A. Goonasekera, Greco B. Malijan, Rebecca J. Sardell, Natalie Staplin, Benjamin S. Storey, Daniel Chapman, Michael Hill, Stewart Moffat, Abdulrahman Al-Mohammad, Doreen Zhu, Nigel J. Brunskill, John J.V. McMurray, Maarten W. Taal, William G. Herrington, Martin J. Landray, Colin Baigent, Richard Haynes, Parminder K. Judge

10.1159/000552348
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Frequently asked questions

How long does it take to publish?

Accepted papers appear online in the unedited manuscript version within a few days of acceptance. The final version is published within 5-6 weeks of acceptance. Proof corrections are expected within 48 hours.

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Is a cover letter required?

A cover letter is required. It should describe the gap in knowledge addressed by the manuscript, explain the implications and significance of the research, show how the manuscript fits the journal scope, and highlight its unique contributions. Special issue or article collection submissions should name the collection and identify the inviter where appropriate.

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What are the publication costs?

Subscription journal. 2026 online access costs are CHF 6726.00/year, EUR 6726.00/year, or USD 7473.00/year for institutional subscribers, and CHF 1345.00/year, EUR 1345.00/year, or USD 1494.00/year for personal subscribers. Prices exclude VAT and local sales tax.

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Research Topics

Dialysis and Renal Disease Management Chronic Kidney Disease and Diabetes Renal Diseases and Glomerulopathies Acute Kidney Injury Research Parathyroid Disorders and Treatments Diverse Scientific and Economic Studies Renal Transplantation Outcomes and Treatments Human auditory perception and evaluation Erythropoietin and Anemia Treatment Renal and Vascular Pathologies Blood Pressure and Hypertension Studies Vasculitis and related conditions Potassium and Related Disorders Ion Transport and Channel Regulation History of Medicine Studies Electrolyte and hormonal disorders Physics and Engineering Research Articles Amyloidosis: Diagnosis, Treatment, Outcomes Renal function and acid-base balance Central Venous Catheters and Hemodialysis Organ Donation and Transplantation Kidney Stones and Urolithiasis Treatments Renin-Angiotensin System Studies Heart Failure Treatment and Management Genetic and Kidney Cyst Diseases