Overview Submission Instructions Recent Publications Frequently Asked Questions Research Topics

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Therapeutic Advances in Chronic Disease

Therapeutic Advances in Chronic Disease is a peer-reviewed open access journal focused on high-quality research, reviews, and scholarly commentary on innovative studies across chronic diseases, with a strong clinical and pharmacological emphasis for clinicians and researchers.

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Subject Pharmacology & Pharmacy

Impact Factor 2.8

Quartile Q2

Open Access Type Open

ISSN 2040-6223

eISSN 2040-6231

Invitation Only No

Cost Range Standard APC: $3000 USD; Editorials and Letters to the Editor: free of charge; Plain Language Summary of Publications (PLS-Ps): $5000.

Submission Instructions

Therapeutic Advances in Chronic Disease accepts the following article types. Click on an article type to view submission instructions.

Original Articles

Cover Letter A cover letter is required. Cover letter must indicate why the manuscript is suitable for publication and must disclose any third-party writing or editing assistance or submission by someone not listed as an author, if applicable.

Abstract A structured abstract is required. Abstract must be no more than 300 words. Abstract must be structured. Abstract must include the headings Background, Objectives, Design, Methods, Results, Conclusion, and Registration if applicable.

Manuscript Manuscript should be up to 6000 words excluding tables, figure legends, and references. Manuscript generally includes Abstract, Introduction, Methodology, Results, Discussion, Conclusion, Acknowledgments, Statements and Declarations, and References. Manuscript must include at least 2 keywords after the abstract, a plain language title of approximately 50 words and plain language summary of approximately 300 words, an Author Contributions heading, a 'Statements and Declarations' section with all required subheadings including 'Not applicable' where relevant, disclosure of AI usage when required, and a statement in the methods identifying which reporting guidelines were consulted.

References References must follow Sage Vancouver style. Every in-text citation must have a corresponding reference list entry and vice versa, with identical spelling and year in corresponding citations.

Figures & Tables Figures must be uploaded as separate files, while figures, charts, and tables created in Word should be included in the main text with a placeholder note in the running text for separately submitted figures. Figures must be numbered consecutively and include a number and title, and tables must be editable in Word with a number, title, and header row and/or column.

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Review Articles

Abstract An abstract is required. Abstract must be unstructured and no more than 300 words. Abstract must be unstructured.

Manuscript Manuscript should be around 4000–6000 words excluding tables, figure legends, and references. Manuscript generally includes an Abstract, Introduction, Methodology, Results, Discussion, Conclusion, Acknowledgments, Statements and Declarations section, and References. Manuscript must include at least 2 keywords after the abstract, a plain language summary and plain language title, an Author Contributions heading after the Acknowledgements section, and a 'Statements and Declarations' section with each required subheading included even when marked 'Not applicable'.

Figures & Tables Figures must be uploaded as separate files, while figures, charts, and tables created in Word should be included in the main text with a placeholder note in the running text for separately submitted figures. Figures must be numbered consecutively and include a number and title, and tables must be editable text in Word with a number, title, and header row and/or column.

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Scoping Reviews

Cover Letter A cover letter is required. Cover letter must indicate why the manuscript is suitable for publication and disclose any third-party writing or editing assistance or submission by someone not listed as an author, if applicable.

Abstract A structured abstract is required. Abstract must be no more than 300 words. Abstract must be structured. Abstract must include the headings Background, Objectives, Eligibility Criteria, Sources of Evidence, Charting Methods, Results, and Conclusions.

Manuscript Manuscript should be around 4000–6000 words excluding tables, figure legends, and references. Manuscript must be identified in the title as a scoping review. Manuscript must include at least 2 keywords after the abstract, a plain language title of approximately 50 words and plain language summary of approximately 300 words, an Author Contributions heading, a 'Statements and Declarations' section with each required subheading including 'Not applicable' where relevant, and AI usage disclosure in the Acknowledgements or Methodology section when required by journal policy.

Figures & Tables Figures must be uploaded as separate files, while figures, charts, and tables created in Word should be included in the main text with a placeholder note in the running text for separately submitted figures. Figures must be numbered consecutively and include a number and title, and tables must be labeled as tables with a number, title, and header row and/or column and be editable within Word rather than submitted as images.

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Systematic Reviews

Cover Letter A cover letter is required. The cover letter must explain why the manuscript is suitable for publication and must disclose any third-party writing or editing assistance or submission by someone not listed as an author, if applicable.

Abstract A structured abstract is required. Abstract must be no more than 300 words. Abstract must be structured. Abstract must include Background, Objectives, Design, Data Sources and Methods, Results, Conclusion, and Registration (if applicable).

Manuscript Manuscript should be around 4000–6000 words excluding tables, figure legends, and references. Manuscript generally includes Abstract, Introduction, Methodology, Results, Discussion, Conclusion, Acknowledgments, Statements and Declarations, and References. The manuscript must include at least 2 keywords after the abstract, a plain language summary, an Author Contributions heading after the Acknowledgements section, a 'Statements and Declarations' section at the end with each required subheading including 'Not applicable' where relevant, and AI usage disclosure in the Acknowledgements or Methodology section when applicable.

Figures & Tables Figures must be uploaded as separate files, while figures, charts, and tables created in Word should be included in the main text with a placeholder note in the running text for separately submitted figures. Figures must be numbered consecutively and include a number and title, and tables must be labeled as tables with a number, title, header row and/or column, and editable text rather than images.

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Meta-Analyses

Cover Letter A cover letter is required. The cover letter must indicate why the manuscript is suitable for publication and must disclose any third-party writing or editing assistance or submission by someone not listed as an author, if applicable.

Abstract A structured abstract is required. The abstract must be no more than 300 words. The abstract must be structured. The abstract must include Background, Objectives, Design, Data Sources and Methods, Results, Conclusion, and Registration (if applicable).

Manuscript The manuscript should be around 4000–6000 words excluding tables, figure legends, and references. Manuscripts generally include an Abstract, Introduction, Methodology, Results, Discussion, Conclusion, Acknowledgments, Statements and Declarations section, and References. The manuscript must include at least 2 keywords after the abstract, a plain language title of approximately 50 words and plain language summary of approximately 300 words entered in the submission system, an Author Contributions heading, a 'Statements and Declarations' section with each required subheading including 'Not applicable' where relevant, and AI usage disclosure in the Acknowledgements or Methodology section when applicable.

References References must follow the Sage Vancouver reference style. Every in-text citation must have a corresponding reference list entry and vice versa, with identical spelling and year in corresponding citations.

Figures & Tables Figures must be uploaded as separate files, while figures, charts, and tables created in Word should be included in the main text with a placeholder note in the running text for separately submitted figures. Figures must be numbered consecutively and include a number and title, and tables must be labeled as tables with a number and title, include a header row and/or column, and be editable within Word rather than included as images.

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Case Reports

Cover Letter A cover letter is required. The cover letter must indicate why the manuscript is suitable for publication and must disclose any third-party writing/editing assistance or submission prepared by someone not listed as an author, if applicable.

Abstract An abstract is required. The abstract must be unstructured and no more than 300 words. The abstract must be unstructured.

Manuscript The manuscript should be up to 2500 words excluding tables, figure legends, and references. Include at least 2 keywords after the abstract, a plain language summary and plain language title, an Author Contributions heading, a 'Statements and Declarations' section, and disclose AI usage in the Acknowledgements or Methodology section when applicable.

Figures & Tables Figures must be uploaded as separate files, while figures, charts, and tables created in Word should be included in the main text with a placeholder note in the running text for separately submitted figures. Figures must be numbered consecutively, and tables must be editable in Word rather than submitted as images.

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Case Series

Cover Letter A cover letter is required. Cover letter must explain why the manuscript is suitable for publication and must disclose any third-party writing or editing assistance or submission by someone not listed as an author, if applicable.

Abstract An abstract is required. Abstract must be unstructured and no more than 300 words. Abstract must be unstructured.

Manuscript Manuscript should be up to 6000 words excluding tables, figure legends, and references. Manuscript generally includes Abstract, Introduction, Methodology, Results, Discussion, Conclusion, Acknowledgements, Statements and Declarations, and References. Manuscript must include at least 2 keywords after the abstract, a plain language title and plain language summary, an Author Contributions heading, a Statements and Declarations section, and disclosure of AI usage in the Acknowledgements or Methodology section when applicable.

References References must follow Sage Vancouver style. Every in-text citation must have a corresponding reference list entry and vice versa, with identical spelling and year in matching citations.

Figures & Tables Figures must be uploaded as separate files, while figures, charts, and tables created in Word should be included in the main text with a placeholder note in the running text for separately submitted figures. Figures must be numbered consecutively and include a number and title, and tables must be editable text in Word with a number and title rather than images.

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Brief Reports

Abstract A structured abstract is required. Abstract must be no more than 150 words. Abstract must be structured. Abstract must include Background, Objectives, Design, Methods, Results, and Conclusion.

Manuscript Manuscript must be up to 2000 words excluding tables, figure legends, and references. Manuscript generally includes Abstract, Introduction, Methodology, Results, Discussion, Conclusion, Acknowledgments, Statements and Declarations, and References. Manuscript must include at least 2 keywords after the abstract, a plain language title and plain language summary, an Author Contributions heading after Acknowledgements, a 'Statements and Declarations' section at the end, and a statement in the methods identifying which reporting guidelines were consulted.

References References are limited to 20. References must follow Sage Vancouver style. Every in-text citation must have a corresponding reference list entry and vice versa, with identical spelling and year in corresponding citations.

Figures & Tables Figures and tables are limited to 2 in total. Figures must be uploaded as separate files, while figures, charts, and tables created in Word should be included in the main text with a placeholder note in the running text for separately submitted figures. Figures must be numbered consecutively in the order cited, and tables must be editable text in Word rather than images.

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Letters To The Editor

Abstract Letters To The Editor must not include an abstract.

Manuscript Letters To The Editor must be up to 500 words excluding references. The manuscript must include at least 2 keywords and a section headed 'Statements and Declarations' at the end of the article, and if no abstract is included the plain language summary fields must be completed with “N/A”.

References Letters To The Editor are limited to 10 references. References must follow Sage Vancouver style. Every in-text citation must have a corresponding reference list entry and vice versa, with identical spelling and year in each paired citation and reference.

Figures & Tables Letters To The Editor are limited to one figure or one table. Figures must be uploaded as separate files. Figures must be numbered consecutively in the order they appear in the text, and tables must be editable text with a number and title.

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Recent Publications

Treatment of vitiligo with ruxolitinib cream in the TRuE-V1 and TRuE-V2 studies: a plain language summary of publication

David Rosmarin, Thierry Passeron, Amit G. Pandya, Pearl Grimes, John E. Harris, Seemal R. Desai, Mark Lebwohl, Mireille Ruer‑Mulard, Julien Seneschal, Albert Wolkerstorfer, Deanna Kornacki, Kang Sun, Kathleen Butler, Khaled Ezzedine

10.1177/20406223251378246

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The evolving roles of fetuin-A in type 2 diabetes mellitus and its potential clinical implications: a review

Mohammed Jemal, Nuredin Chura Waritu, Temesgen Baylie, Deresse Sinamaw, Enyew Fenta Mengistu, Enatnesh Essa Osman, Gelagey Baye, Bantayehu Addis Tegegne, Gashaw Azanaw Amare, Zigale Hibstu Teffera, Tabarak Malik, Birhanu Malede, Baye Ashenef, Desalegn Abebaw, Adane Adugna

10.1177/20406223251389795

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The relationship between MAFLD and CVD in a health check-up Chinese population: a prospective cohort study

Yao Dou, Jiawei Cui, Qi Gu, Xiwei Yuan, Mengmeng Hou, Wenjing Ni, Chen Dong, Chudi Chang, Jinhua Shao, Qiuling Wang, Jie Li, Liang Qiao, Yuemin Nan

10.1177/20406223251378867

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Short- and long-term complications of insulin pump therapy in children and adolescents with type 1 diabetes: a multicenter cross-sectional study from Saudi Arabia

Ayman Bakkar, Enad Althobaiti, Ibtisam Alqahtani, Lujain A Abualkhair, Naglaa M Kamal, Mohammed Althobaiti, Turki Alotaibi, Lura Habib, Lujain Alharthi, Saad Aljuaid, Maha Althuwaybi, Haneen Alshehri, Muhannad Alotaibi, Wael Kamal, Mutlaq Aljuaid, Samia Almalki, Abdulaziz Alsaedi

10.1177/20406223251381573

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Level of medication non-adherence among ambulatory patients with dyslipidemia and comorbid illness in Northwest Ethiopia: a multicenter cross-sectional study

Tilaye Arega Moges, Samuel Berihun Dagnew, Sisay Sitotaw Anberbr, Bayih Endalew Bitew, Mekdes Kiflu, Yared Andargie Ferede, Tesfagegn Gobezie Yiblet, Woretaw Sisay Zewdu

10.1177/20406223251381590

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Frequently asked questions

How long does it take to publish?

Accepted articles can appear online within an average of 30 days after the APC has been processed.

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Is a cover letter required?

A cover letter is required and should explain why the manuscript is suitable for publication. Writing assistance or third-party submission must also be disclosed in the covering letter.

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What are the publication costs?

The journal is open access. The standard APC is $3000 USD, payable after acceptance and before publication. Editorials and Letters to the Editor are free of charge. Plain Language Summary of Publications (PLS-Ps) have an APC of $5000.

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Research Topics

Liver Disease Diagnosis and Treatment Diabetes, Cardiovascular Risks, and Lipoproteins Rheumatoid Arthritis Research and Therapies Psoriasis: Treatment and Pathogenesis Asthma and respiratory diseases Spondyloarthritis Studies and Treatments Chronic Obstructive Pulmonary Disease (COPD) Research Diabetes Treatment and Management Inflammatory Bowel Disease Respiratory and Cough-Related Research Multiple Sclerosis Research Studies Dialysis and Renal Disease Management Gastroesophageal reflux and treatments Chronic Kidney Disease and Diabetes Parathyroid Disorders and Treatments Retinal Diseases and Treatments Liver Disease and Transplantation Hormonal Regulation and Hypertension Bone health and osteoporosis research Blood Pressure and Hypertension Studies Helicobacter pylori-related gastroenterology studies Dermatology and Skin Diseases Nutrition and Health in Aging Diabetes Management and Research Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

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