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Blood Cancer Discovery

Blood Cancer Discovery provides a critical outlet for high-impact basic, translational, and clinical research on all disease subtypes of leukemia, lymphoma, myeloma, and associated diseases.

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Subject Hematology, Oncology
Impact Factor 11.5
Quartile Q1
Open Access Type Hybrid
ISSN 2643-3230
eISSN 2643-3249
Invitation Only No
Cost Range Manuscript submission fee $35; base publication fee $2500; display item fee $250 per item; open access APC $7000 for CC BY-NC-ND or $8000 for CC BY.

Submission Instructions

Blood Cancer Discovery accepts the following article types. Click on an article type to view submission instructions.

Research Article

Cover Letter Cover letter is strongly encouraged for initial submission. Cover letter must describe how any associated manuscript is related to the current submission.
Abstract Abstract is required. Abstract must be 150 words. Abstract structure is not specified. Abstract headings are not specified.
Manuscript Manuscript must contain 6,000 words of text. Manuscript sections should be ordered as title page, abstract, statement of significance, introduction, results, discussion, methods, references, tables, table legends, figure legends, and figures, and the Results and Discussion sections must not be combined. Manuscript must include a 50-word statement of significance and must declare any use of generative AI or human-assisted editing services in the acknowledgments section.
References Manuscript must include 50 references.
Figures & Tables Manuscript may include a total of 7 figures and/or tables. For initial submission, each figure should be placed in sequential order adjacent to its legend, ideally where it is first cited in the text. Each figure or table must fit on a single printed page.
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Review

Cover Letter Cover letter is strongly encouraged but not required. Cover letter must describe how any associated manuscript is related to the current submission.
Abstract Abstract is required for Reviews. Abstract must be 100 words.
Manuscript Reviews must contain 7,000 words of text. Reviews must include a 3-4 sentence statement of significance, and any use of generative AI for manuscript preparation must be declared in the acknowledgments or other appropriate manuscript section.
References Reviews must include 100 references.
Figures & Tables Reviews may include up to 6 original figures and/or tables. For initial submission, figures should be embedded in a single manuscript file adjacent to their legends, while supplementary data must be uploaded separately.
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Mini-Review

Cover Letter Cover letter is strongly encouraged for initial submission. Cover letter must describe how any associated manuscript is related to the current submission.
Abstract Abstract is required. Abstract must be 100 words.
Manuscript Manuscript must contain 4,000 words of text. Manuscript must include a 1–2 sentence statement of significance and any use of generative AI for manuscript preparation must be declared in the acknowledgments section.
References Manuscript must include 50 references.
Figures & Tables Mini-Review may include a total of 3 figures and/or tables. For initial submission, figures should be presented in sequential order adjacent to their legends, ideally where first cited in the text, and supplementary data should be uploaded separately. Each figure or table must fit on a single printed page.
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Research Briefs

Cover Letter Cover letter is strongly encouraged for initial submission. Cover letter must describe how any associated manuscript is related to the current submission.
Abstract Abstract is required. Abstract must be 150 words. Abstract structure type is not specified.
Manuscript Manuscript must contain 3,500 words of text. Sections must be ordered as title page, abstract, statement of significance, introduction, results, discussion, methods, references, tables, table legends, figure legends, and figures, and the Results and Discussion sections must not be combined. Manuscript must include a 50-word statement of significance and a declaration of any generative AI or human-assisted editing use in the acknowledgments, with any AI used to produce manuscript content described in an appropriate manuscript section.
References Manuscript must include 25 references.
Figures & Tables Research Briefs may include a total of 4 figures and/or tables. For initial submission, figures should be presented in sequential order and adjacent to their legends, ideally where first cited in the text, and the section order places tables, table legends, figure legends, and figures after the references. Each figure or table must fit on a single printed page.
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Letter To The Editor

Cover Letter Cover letter is strongly encouraged but not required. Cover letter must describe how any associated manuscript is related to the current submission.
Abstract Abstract requirements are not specified.
Manuscript Letter To The Editor must contain 500 words of text. Letter To The Editor must focus on and refer to an article published in Blood Cancer Discovery within the previous 3 months, and the title should read as 'Running title of the original article' — Letter. Any use of generative AI for manuscript preparation must be declared in the acknowledgments section, and any use of AI to produce new text, images, or other material must be described in an appropriate section of the manuscript.
References Letter To The Editor must include 5 references. The first reference must cite the originating article.
Figures & Tables Figures or tables are permitted only if they show data that refute the conclusions of the originating article. For initial submission, figures should be presented in sequential order adjacent to their legends, ideally where first called out in the text, in a single manuscript file.
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Recent Publications

CAR T Cells Targeting an Intracellular Leukemia Antigen Promiscuously Presented by Diverse HLA-II Alleles

Evey Y.F. Zheng, Chung-Hsi Wang, Toshiki Ochi, Yota Ohashi, Fumie Ihara, Saori Fukao, Yusuke Ito, Giselle M. Boukhaled, Ben X. Wang, Dong-Hoon Han, Xinyu Wei, Priyanka Yolmo, Brian D. Burt, Kayoko Saso, Yukiko Matsunaga, Dalam Ly, Yuki Kagoya, Marcus O. Butler, Mark D. Minden, Naoto Hirano

10.1158/2643-3230.bcd-25-0230
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Sequenced, Not Stirred: Positioning CAR T and Bispecific Antibody Therapy in Multiple Myeloma

Rahul Banerjee

10.1158/2643-3230.bcd-26-0256
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Personalized Circulating Tumor DNA Profiling Enables Superior and Universal Residual Disease Detection in Acute Myeloid Leukemia

Ruwan Gunaratne, Crystal M. Zhou, Sanjeeth Rajaram, Jesse W. Tai, Kailee L. Tanaka, Charu Tiwari, Emily Y. Yang, Sky Kim, Grace Gao, Raymond Yin, Mia Carleton, Matthew S. Alkaitis, Matthew Schwede, Brian J. Sworder, Gabriel N. Mannis, Michael S. Khodadoust, Ravindra Majeti, David M. Kurtz, Tian Yi. Zhang

10.1158/2643-3230.bcd-26-0159
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Glofitamab-Based Therapy for Relapsed or Refractory CNS Lymphoma: A Multicenter Retrospective Study

Ruixian Xing, Apeng Yang, Juan Huang, Liang Wang, Wei Guo, Qu Cui, Xiaoqiong Tang, Yuanyuan Ma, Kai Hu, Tianheng He, Danyang Wu, Xiaofang Deng, Yajing Zhang, Kaili Zhong, Yang Liu, Yixian Guo, Ying Wang, Chan Long, Chongyang Wu, Xin Lu, Fengmin Li, Jiefei Bai, Jun Qian, Xuefei Sun, Wenrong Huang, Hui Zhou, Huilai Zhang, Ou Bai, Xiaobing Huang, Zhiyong Zeng, Lin Fu

10.1158/2643-3230.bcd-26-0128
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Predictive Models for Toxicities after CAR T-cell Therapy: Challenges and Opportunities

Julie Ma, August Culbert, Tian-Gen Chang, Mark L. Solter, Eytan Ruppin, Kai Rejeski, Nirali N. Shah

10.1158/2643-3230.bcd-25-0458
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Frequently asked questions

How long does it take to publish?

Decisions are typically returned within 35 days of submission. Accepted author manuscripts are usually posted OnlineFirst within 48 hours following formal acceptance.

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Is a cover letter required?

Authors are strongly encouraged to upload a cover letter for initial submission.

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What are the publication costs?

Manuscript submission fee $35; base publication fee $2500 under copyright transfer; open access APC $7000 for CC BY-NC-ND or $8000 for CC BY.

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Research Topics

Acute Myeloid Leukemia Research CAR-T cell therapy research Lymphoma Diagnosis and Treatment Protein Degradation and Inhibitors Chronic Lymphocytic Leukemia Research Cancer Genomics and Diagnostics Multiple Myeloma Research and Treatments Acute Lymphoblastic Leukemia research Chronic Myeloid Leukemia Treatments Monoclonal and Polyclonal Antibodies Research Ubiquitin and proteasome pathways Myeloproliferative Neoplasms: Diagnosis and Treatment Immune Cell Function and Interaction RNA modifications and cancer Immunotherapy and Immune Responses Immune cells in cancer Epigenetics and DNA Methylation Hematopoietic Stem Cell Transplantation Histone Deacetylase Inhibitors Research Single-cell and spatial transcriptomics Cancer Immunotherapy and Biomarkers RNA Research and Splicing Cancer-related gene regulation Peptidase Inhibition and Analysis Cancer, Hypoxia, and Metabolism