Overview Submission Instructions Recent Publications Frequently Asked Questions Research Topics

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npj Precision Oncology

npj Precision Oncology is a Nature Portfolio journal in the npj Series, published in partnership with The Hormel Institute, featuring open access research, reviews, comments, and special collections in precision oncology.

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Subject Oncology

Impact Factor 8

Quartile Q1

Open Access Type Open

eISSN 2397-768X

Invitation Only No

Cost Range Original Research: £3190.00 / $4290.00 / €3490.00; Brief Communication, Perspective, Review, Comment, Protocol, Case Report: £1255.00 / $1780.00 / €1420.00; VAT or local taxes may apply.

Submission Instructions

npj Precision Oncology accepts the following article types. Click on an article type to view submission instructions.

Article

Cover Letter A cover letter should be provided with the submission. Cover letter should include the corresponding author's affiliation and contact information, briefly explain the context and importance of the work and its suitability for the journal, and include confidential disclosures such as competing interests and related work in press or submitted elsewhere.

Abstract An abstract is required. Abstract must be no more than 150 words. Abstract must be unstructured with no subheadings.

Manuscript Manuscript should include an Introduction without subheadings, Results with subheadings, Discussion without subheadings and without separate limitations or conclusions sections, and Methods with subheadings, with all Methods described in the main manuscript file rather than the Supplementary Information. Manuscript must include a mandatory Data availability section, a Code availability section where applicable, an Author contributions statement identifying each author by initials, a Competing Interests statement, and documentation of any Large Language Model use in the Methods section or a suitable alternative section if no Methods section is present.

References References are limited to 60, though this limit is not strictly enforced. References must use standard Nature referencing style. References must be numbered sequentially in order of appearance, include all authors unless there are more than five in which case only the first author is listed followed by 'et al.', and include only one publication per reference number.

Figures & Tables Figures should generally be inserted within the text at appropriate positions for initial submission, while tables must be submitted at the end of the text document. Figure legends must not exceed 350 words per figure, and multi-panel figures must be presented on a single page with panels labeled a), b), c).

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Review

Cover Letter A cover letter is required. Cover letter should include the corresponding author's affiliation and contact information and briefly explain the context, importance, and journal fit of the work.

Abstract An abstract is required. Abstract must be no more than 70 words. Abstract must be unstructured with no subheadings.

Manuscript Main text is typically 3,000–4,000 words in length. Subheadings are permitted in the main text. Manuscript must include an author contributions statement naming each author by initials, a statement of responsibility specifying every author's contribution, and a competing interests statement declaring all financial and non-financial interests or none.

References References are limited to 60, though this limit is not strictly enforced. References must use Nature referencing style. References must be numbered sequentially as they appear and list all authors unless there are more than five, in which case the first author is followed by 'et al.'.

Figures & Tables At initial submission, figures should be incorporated into the main article file, while tables must be submitted at the end of the text document. Figure legends must not exceed 350 words per figure, and multi-panel figures must be presented on a single page with panels labeled a), b), c), and so on.

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Brief Communication

Cover Letter A cover letter should be provided with the submission. The cover letter should include the corresponding author's affiliation and contact information and briefly explain the context, importance, and journal fit of the work.

Abstract An abstract is required. Abstract must be no longer than 70 words. Abstract must be unstructured with no subheadings.

Manuscript Main text should be 1,000–1,500 words excluding the abstract, Methods, references, and figure legends. Methods descriptions must be included in the main manuscript file, and the Methods section should use subheadings. The manuscript must include Data availability, Author contributions, and Competing Interests sections, and a Code availability section where applicable.

References Brief Communications should include around 20 references as a guide. References must use Nature referencing style. References must be numbered sequentially in order of appearance, include all authors unless there are more than five in which case only the first author followed by 'et al.' is listed, and only one publication may be assigned to each reference number.

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Case Report

Abstract An abstract is required. Abstract must be no more than 150 words. Abstract must be unstructured with no subheadings.

Manuscript Manuscript should include an Introduction without subheadings, a Results section with subheadings, a Discussion without subheadings and without separate limitations or conclusions sections, and Methods in the main manuscript file with subheadings. Manuscript must include Data availability, Author contributions, and Competing Interests statements, include a Code availability section where applicable, declare funding in the Acknowledgments, and document any use of a Large Language Model in the Methods or another suitable section if no Methods section is available.

References Case Reports have around 50 references as a guide. References must use standard Nature referencing style. References must be numbered sequentially in order of appearance, use one publication per reference number, and list all authors unless there are more than five, in which case the first author should be followed by 'et al.'.

Figures & Tables At initial submission, figures should be incorporated into the main article file, while tables must be submitted at the end of the text document and figure legends placed in the main manuscript file after the references. Figure legends must not exceed 350 words per figure, and multi-panel figures must be presented on a single page with panels labeled a), b), c).

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Recent Publications

Fuzuloparib enhances radiosensitivity of gain-of-function mutant p53 R273H NSCLC by promoting SLC7A11/GSH/GPX4 axis mediated ferroptosis

Mengjia Wu, Chaoyuan Pu, Wanxuan Weng, Fengmin Yin, Lei Zhang, Chenggang Xu, Mingjian Li, Chuanhui Cao, Wei Hu

10.1038/s41698-026-01526-7

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Distinctive features of the tumor and immune microenvironment in glioblastoma

Elena Shklovskaya, Bernadette Pedersen, Su Yin Lim, Mal Irvine, Jesse R. Brown, Andreia V. Pinho, Brindha Shivalingam, Alexander M. Menzies, Laveniya Satgunaseelan, Kimberley L. Alexander, Antonio Di Ieva, Georgina V. Long, Wei Yen Chan, Helen Rizos

10.1038/s41698-026-01537-4

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Cyclin E1 overexpression identifies a therapeutically relevant poor prognostic patient subgroup in high-grade serous ovarian cancer

Doris Kim, Heekyung Chung, Mona Abed, Jianhui Ma, Nandini Molden, Changhwan Shim, Divya Rajendran, James Yen, Jinkil Jeong, Alexandra Levy, Elisa Yaniz-Galende, Felix Blanc-Durand, Christophe Desauw, Philippe Follana, Nathalie Bonichon-Lamichhane, Stéphane Oudard, Véronique D’Hondt, Céline Gavoille, Danielle D. Jandial, Funda Meric‑Bernstam, Joyce F. Liu, Fiona Simpkins, Leslie M. Randall, Alexandra Leary, Mark R. Lackner, Olivier Harismendy

10.1038/s41698-026-01519-6

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Integrating handcrafted and deep learning MRI signatures: an interpretable framework for predicting chemotherapy benefit in glioma

Shenao Zhang, Jinfeng Bao, Yinjiao Wang, Lang Chen, Yu Guo, Aihong Cao, Peng Du

10.1038/s41698-026-01538-3

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Apatinib enhances anti-PD-1 efficacy by inhibiting Exo70-mediated exosome secretion in pMMR/MSS colorectal cancer

Lingying Zhao, Chunyi Gao, Xiaoxue Qiao, Fanzhuoran Lou, Bowen Zheng, Miao Fu, Xintian Huang, Xiaowen Xie, Wenqing Zhang, Yongxiang Hong, Kaiyi Rong, Huibo Shi, Li Xiao, Tianhui Hu

10.1038/s41698-026-01518-7

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Frequently asked questions

How long does it take to publish?

Median time from submission to first editorial decision is 18 days. Median time from submission to acceptance is 164 days.

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Is a cover letter required?

Authors should provide a cover letter including the affiliation and contact information for the corresponding author. The cover letter should briefly explain the context and importance of the work, why it is appropriate for the journal, and may include confidential information, related work, and suggested or excluded referees.

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What are the publication costs?

An article processing charge is required. Original Research: £3190.00 / $4290.00 / €3490.00. Brief Communication, Perspective, Review, Comment, Protocol, and Case Report: £1255.00 / $1780.00 / €1420.00. VAT or local taxes may apply.

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Research Topics

Cancer Genomics and Diagnostics Cancer Immunotherapy and Biomarkers Radiomics and Machine Learning in Medical Imaging Lung Cancer Treatments and Mutations Ferroptosis and cancer prognosis AI in cancer detection RNA modifications and cancer Cancer Cells and Metastasis Single-cell and spatial transcriptomics Genetic factors in colorectal cancer Glioma Diagnosis and Treatment Immune cells in cancer Epigenetics and DNA Methylation Pancreatic and Hepatic Oncology Research Cancer-related molecular mechanisms research Lung Cancer Research Studies Colorectal Cancer Treatments and Studies Immunotherapy and Immune Responses Cancer, Hypoxia, and Metabolism PARP inhibition in cancer therapy CAR-T cell therapy research Prostate Cancer Treatment and Research Lung Cancer Diagnosis and Treatment HER2/EGFR in Cancer Research Cell Image Analysis Techniques

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