CB

Cancer Biology & Therapy

Cancer Biology & Therapy is an international journal covering all aspects of the molecular basis of cancer with translational relevance to diagnosis and therapy. It publishes original research, reviews, meeting reports, bedside-to-bench reports, letters to the editor, and perspective articles, and operates a single-anonymized peer review policy. The journal became fully Open Access from Volume 23 in 2022.

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Subject Oncology
Impact Factor 4.6
Quartile Q1
Open Access Type Hybrid
ISSN 1538-4047
eISSN 1555-8576
Invitation Only No
Cost Range Open access publishing may be covered by an institutional open access agreement; authors can use an open access cost finder for journal-specific charges.

Submission Instructions

Cancer Biology & Therapy accepts the following article types. Click on an article type to view submission instructions.

Review Article

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required. Abstract must be 150 words. Abstract must be structured.
Manuscript Manuscript must be ordered as title page, abstract, keywords, main text introduction, materials and methods, results, discussion, acknowledgments, declaration of interest statement, references, appendices as appropriate, tables with captions on individual pages, figures, and figure captions as a list. Manuscript must include 5 to 10 keywords and a declaration of interest statement under the subheading "Disclosure of interest," and any use of AI in writing must be acknowledged in the paper.
References References must not exceed 150. References may be in any consistent scholarly citation style or format. References must include complete bibliographic details, every reference entry must have a corresponding in-text citation, and citations in review articles must be relevant, fair, balanced, and not unfairly biased toward any particular research group, organization, or journal.
Figures & Tables Figures and tables may be embedded within the manuscript text or submitted as separate documents. Tables must be placed on individual pages with captions, and figure captions must be provided as a list.
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Research Article

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required and must be structured. Abstract must be 250 words. Abstract must be structured.
Manuscript Manuscript typically includes Abstract, Introduction, Methods, Results, Discussion, and Conclusion sections. Manuscript must include 5 to 10 keywords.
References Manuscript must include no more than 85 references. References may be in any consistent scholarly citation format and each bibliographic entry must have a corresponding in-text citation.
Figures & Tables Figures and tables may be placed within the text or submitted as separate documents. Tables must be numbered consecutively with Arabic numerals and include descriptive titles and legends.
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Bedside-To-Bench Reports

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required.
Manuscript The manuscript must include a disclosure statement under the subheading "Disclosure of interest."
References References may be in any style or format provided a consistent scholarly citation format is used. References must include complete bibliographic details and every reference entry must have a corresponding in-text citation.
Figures & Tables Figures and tables may be placed within the text or submitted as separate documents.
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Letters To The Editor

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Letters To The Editor are limited to 1500 words.
References Letters To The Editor must contain no more than 15 references. References may be in any style or format as long as a consistent scholarly citation format is applied. The article under discussion must be included as one of the references.
Figures & Tables Letters To The Editor must not contain figures or tables. Figures and tables may be placed within the text or submitted as separate documents.
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Recent Publications

Neoplastic CD3⁺ B cells remodel the DLBCL tumor microenvironment via single-cell and spatial transcriptomics

Mingxiao Lang, Youqin Feng, Li Zhou, Bin Li, Wei Li, Jing Zhao, Kexin Chen, Lanfang Li, Lihua Qiu, Zhengzi Qian, Shiyong Zhou, Huilai Zhang, Zhaobin Chu

10.1080/15384047.2026.2684140
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The tumor microenvironment in triple negative breast cancer and a strategy to improve responses to immunotherapy using cryoablation and immunostimulants

Ritvik Illindala, Yunpeng Yang, Tyler Mandt, Nicholas Webster, Nicole Steinmetz, Isabel Newton

10.1080/15384047.2026.2683942
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RET fusion partners dictate oncogenic potential in undifferentiated spindle cell sarcomas

Qi Gui, Ying Zhang, Mei Yang, Rongrui Liang, Man Huang, Xiaoshan Yang, Nan Chen, Xiaojun Chen, Mengyao Wu, Huafei Chen, Lijun Meng, Sheng Xiao, Min Tao

10.1080/15384047.2026.2683190
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Leveraging the bacteria for enhanced cancer immunotherapy: from a perspective of synthetic biology

Xing Liu, Hejin Zhang, Renchun Du, Zixu Liu, Yunyun Ren, Xiao Yang

10.1080/15384047.2026.2683171
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Parthenolide inhibits the progression of intrahepatic cholangiocarcinoma by promoting ferroptosis through inhibiting UBD

Yuanzhu Xie, Jia Wang, Jia Zhou, Yuhuai Peng, Yizhi Wang, Yueren Wang, Yinghui Song

10.1080/15384047.2026.2664327
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Frequently asked questions

How long does it take to publish?

Timely publication of important advances is emphasized.

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What are the publication costs?

Open access publishing costs may be covered by an institutional open access agreement; journal-specific charges vary.

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Research Topics

Cancer-related Molecular Pathways Cancer, Hypoxia, and Metabolism RNA modifications and cancer Cell death mechanisms and regulation Cancer Cells and Metastasis Epigenetics and DNA Methylation Cancer Research and Treatments MicroRNA in disease regulation Cancer Genomics and Diagnostics Cancer-related molecular mechanisms research Lung Cancer Treatments and Mutations Ubiquitin and proteasome pathways Immunotherapy and Immune Responses RNA Interference and Gene Delivery PI3K/AKT/mTOR signaling in cancer Virus-based gene therapy research DNA Repair Mechanisms Pancreatic and Hepatic Oncology Research Cancer, Lipids, and Metabolism HER2/EGFR in Cancer Research Prostate Cancer Treatment and Research Circular RNAs in diseases Angiogenesis and VEGF in Cancer Colorectal Cancer Treatments and Studies Peptidase Inhibition and Analysis