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Clinica Chimica Acta

Clinica Chimica Acta is the official journal of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC). It publishes original research communications in clinical chemistry and laboratory medicine, including diagnostic applications of chemistry, biochemistry, immunochemistry, hematology, toxicology, molecular biology, analytical methodologies, point-of-care testing, laboratory management, informatics, digitalization, mobile health, and artificial intelligence applied to laboratory medicine.

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Subject Medical Laboratory Technology
Impact Factor 2.9
Quartile Q2
Open Access Type Hybrid
ISSN 0009-8981
eISSN 1873-3492
Invitation Only No
Cost Range USD 3460 APC for open access; no open access publication fee for subscription publication.

Submission Instructions

Clinica Chimica Acta accepts the following article types. Click on an article type to view submission instructions.

Research Articles

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 250 words. Abstract must be unstructured.
Manuscript Manuscript must be divided into clearly defined and numbered sections, with the abstract excluded from section numbering. The submission must include 1 to 7 English keywords and 3 to 5 highlights provided as a separate editable Word file, with each highlight limited to 85 characters including spaces.
References At least 10% of the references must originate from clinical laboratory medicine-oriented journals. References must be cited in the text as numbers in square brackets and numbered in the order of first appearance.
Figures & Tables Figures must be supplied as separate files, while tables must be submitted as editable text. All figures and tables must be cited in the text, numbered consecutively in order of appearance, and accompanied by captions.
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Review Articles

Cover Letter Cover Letter requirements are not specified.
Abstract A concise and factual abstract is required. Abstract must not exceed 250 words.
Manuscript Manuscript must be divided into clearly defined and numbered sections, with subsections numbered hierarchically and the abstract excluded from section numbering. Manuscript submission must include 1 to 7 English keywords, 3 to 5 highlights submitted as a separate Word file with bullets of no more than 85 characters each, and disclosure in each image caption and in the general generative AI disclosure statement if generative AI was used to create images.
References At least 10% of the references must originate from clinical laboratory medicine-oriented journals. References must be cited using a numbered square-bracket style. References must be numbered in order of appearance in the text, every in-text citation must appear in the reference list and vice versa, journal names must be abbreviated according to the List of Title Word Abbreviations, and web references must include the full URL and last accessed date.
Figures & Tables Tables must be submitted as editable text, while figures and other artwork must be supplied as separate files along with the manuscript. All tables and figures must be cited in the text, numbered consecutively in order of appearance, and provided with captions, with table notes placed below the table body.
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Registered Reports

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 250 words. Abstract must be unstructured.
Manuscript Manuscript must be divided into clearly defined and numbered sections. The submission must include 1 to 7 English keywords and 3 to 5 highlights submitted as a separate editable Word file, and any generative AI-created images must be disclosed in the relevant image captions.
References At least 10% of the references must originate from clinical laboratory medicine-oriented journals. References must use a numbered square-bracket citation style. References must be numbered in the order they appear in the text, all cited references must appear in the reference list, and journal names must be abbreviated according to the List of Title Word Abbreviations.
Figures & Tables Tables must be included as editable text, while figures and other artwork must be supplied as separate files. Tables must be cited and numbered consecutively in the text and include captions, and all artwork must be cited, numbered in order, and accompanied by captions.
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Registered Report Stage I

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 250 words. Abstract must be unstructured.
Manuscript Manuscript must be divided into clearly defined and numbered sections, with subsections numbered hierarchically and the abstract excluded from section numbering. The submission must include 1 to 7 English keywords and 3 to 5 highlights supplied as a separate Word file, with each highlight limited to 85 characters and avoiding jargon, acronyms, and abbreviations.
References References must use numbered citations in square brackets. References must be numbered in the order of first appearance in the text, every in-text citation must appear in the reference list and vice versa, journal names must be abbreviated according to LTWA, and web references must include the full URL and last accessed date.
Figures & Tables Tables must be submitted as editable text and figures must be supplied as separate files alongside the manuscript. Tables must be cited and numbered consecutively in the text and include captions, and figures must be cited and numbered consecutively in the text and include captions explaining symbols and abbreviations.
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Registered Report Stage Ii

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 250 words. Abstract should be unstructured as a concise and factual standalone summary.
Manuscript Manuscript must be divided into clearly defined and numbered sections, with the abstract excluded from section numbering. The submission must include 1 to 7 English keywords, 3 to 5 highlights provided as a separate editable Word file, and disclosure in image captions and the general disclosure statement if generative AI was used to create images.
References At least 10% of the references must originate from clinical laboratory medicine-oriented journals. References must be cited as numbered citations in square brackets. References must be numbered in order of appearance in the text, all cited references must appear in the reference list and vice versa, and journal names must be abbreviated according to the List of Title Word Abbreviations.
Figures & Tables Figures must be supplied as separate files, while tables must be submitted as editable text. All figures and tables must be cited in the text, numbered according to order of appearance, and accompanied by captions.
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Case Reports

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 250 words. Abstract must be unstructured.
Manuscript Manuscript must be divided into clearly defined and numbered sections. The manuscript submission must include 1 to 7 English keywords, 3 to 5 highlights submitted as a separate editable Word file, and disclosure in each image caption and the general disclosure statement if generative AI was used to create images.
References References must be cited using numbered citations in square brackets. References must be numbered in the order they appear in the text and journal names must be abbreviated according to the List of Title Word Abbreviations.
Figures & Tables Figures must be uploaded as separate files, while tables must be submitted as editable text. All figures and tables must be cited in the text, numbered consecutively in order of appearance, and accompanied by captions.
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Recent Publications

Editorial Board

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10.1016/s0009-8981(26)00341-4
View Publication

Running title: HF-related pleural effusion biomarkers

Yi-Lu Hao, Yan Niu, Jian-Xun Wen, Qi-Jia Wang, Qiu-Fen Tian, Rui Niu, Li Yan, Ran-Tong Bao, Wen-Qi Zheng, Ya-Nan Xu, Zhi-De Hu

10.1016/j.cca.2026.121186
View Publication

TIM-3 as an immune and leukemia stem-cell biomarker in acute myeloid leukemia: diagnostic laboratory and translational perspectives

Asif Ahmad Bhat, Shivkanya Fuloria, Riya Thapa, Kamal Narain, Sumita Bhatia, Mohammed Tahir Ansari, Supriya Agnihotri, Yuan Seng Wu, Dhanalekshmi Unnikrishnan Meenakshi, Neeraj Kumar Fuloria

10.1016/j.cca.2026.121187
View Publication

Circulating NETosis biomarkers in oncology

Mohd Imran, A. Khuzaim Alzaharani, Hayaa M. Alhuthali, Shatha Alzahrani, Amani A. Alrehaili, Abdulkarim Alshammari, Zia Ur Rehman, Abida Khan

10.1016/j.cca.2026.121185
View Publication

Letter to the editor regarding: “Glycosylation-associated plasma SNORD99 as a novel diagnostic biomarker for early-stage lung adenocarcinoma”. Clinica Chimica acta 580(2026) 120722

Pei Gao, Fu Liu, Meiyuan Liu, Juan Yu

10.1016/j.cca.2026.121188
View Publication

Frequently asked questions

How long does it take to publish?

4 days from submission to first decision; 23 days from submission to decision after review; 52 days from submission to acceptance; 2 days from acceptance to online publication.

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What are the publication costs?

Open access APC: USD 3460 excluding taxes. Subscription publication has no open access publication fee.

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Research Topics

Metabolism and Genetic Disorders Diabetes, Cardiovascular Risks, and Lipoproteins Clinical Laboratory Practices and Quality Control Metabolomics and Mass Spectrometry Studies Neonatal Health and Biochemistry Liver Disease Diagnosis and Treatment Glycosylation and Glycoproteins Research Diverse Scientific and Economic Studies Human auditory perception and evaluation Educational Robotics and Engineering Erythrocyte Function and Pathophysiology Lipoproteins and Cardiovascular Health Folate and B Vitamins Research Hemoglobinopathies and Related Disorders Biochemical and Molecular Research Analytical Chemistry and Chromatography Lysosomal Storage Disorders Research Monoclonal and Polyclonal Antibodies Research Amino Acid Enzymes and Metabolism Adipokines, Inflammation, and Metabolic Diseases Hormonal and reproductive studies Muscle metabolism and nutrition Renal function and acid-base balance Iron Metabolism and Disorders Diet and metabolism studies

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