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Clinical and Molecular Hepatology

Clinical and Molecular Hepatology is an international, peer-reviewed, open-access journal published quarterly in English. It focuses on advanced knowledge, trends, and understanding of hepatobiliary diseases, aims to support debate among clinical doctors, translational researchers, and basic scientists, and emphasizes public health through a multidisciplinary approach, especially in resource-limited Asia-Pacific regions with high prevalence of hepatitis B viral infection and hepatocellular carcinoma. The journal gives priority to epidemiological studies of hepatobiliary diseases across Asia, Africa, parts of Europe, and the Americas, and publishes original papers, meta-analyses, letters to the editor, case reports, reviews, guidelines, editorials, and liver image and pathology articles in hepatology.

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Subject Gastroenterology & Hepatology
Impact Factor 16.9
Quartile Q1
Open Access Type Open
ISSN 2287-2728
eISSN 2287-285X
Invitation Only No
Cost Range APC is US$1,500 (KRW 2,000,000) for articles submitted starting February 5, 2024; for articles submitted on or after February 1, 2026, APC is US$2,000 (KRW 3,000,000) for original articles and unsolicited review articles. Fast-track review carries an additional non-refundable processing fee of US$1,000, and if accepted an additional article processing charge of US$1,500 is charged.

Submission Instructions

Clinical and Molecular Hepatology accepts the following article types. Click on an article type to view submission instructions.

Original Articles

Cover Letter Cover Letter requirements are not specified.
Abstract Original Articles must include an abstract. Abstract must not exceed 250 words. Abstract must be structured. Abstract headings must be Background/Aims, Methods, Results, and Conclusions, followed by five or fewer keywords.
Manuscript Manuscript must not exceed 6,000 words excluding the abstract, references, tables, and figure legends. Manuscript must be arranged as title page, abstract, introduction, materials and methods or patients and methods, results, discussion, acknowledgements, conflict of interest statement, references, tables, and figure legends. Manuscript must include a graphical abstract submitted as a separate JPG or TIFF file and Highlights of three to four sentences in a box after the abstract with a total length of no more than 100 words, and any AI use must be disclosed in the Acknowledgement section with the software details, how it was used, and author responsibility for the content.
References References must not exceed 50. References must be numbered in the order cited using superscript Arabic numerals, include only published or in-press literature, cite all authors when there are six or fewer, and list the first six followed by et al. when there are seven or more.
Figures & Tables Original Articles may include no more than 8 figures and tables in total, and each figure may contain a maximum of 6 panels. Graphical abstract must be uploaded separately as a JPG or TIFF file. Figures must be numbered in the order mentioned in the text, and figure legends must be provided on a separate sheet with a title and enough explanation to be understood without the text.
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Review Articles

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required. Abstract must contain 250 words or less. Abstract must be structured. Abstract must use the headings Backgrounds/Aims, Methods, Results, and Conclusions, and include no more than 5 keywords at the end.
Manuscript Review Articles must not exceed 5,000 words. Manuscript text must include Introduction, Materials and Methods, Results, and Discussion sections. Manuscript must include a title page, abstract, acknowledgements, conflict of interest statement, references, tables, and figure legends, and any AI use must be disclosed in the Acknowledgement section with the tool details, how it was used, and a statement that the authors take full responsibility for the content.
References References must be numbered in the order cited with superscript Arabic numerals in the text, include only published or in-press literature, list all authors when there are six or fewer, and list the first six followed by et al. when there are seven or more.
Figures & Tables Review Articles may include a maximum of 8 tables and/or colored figures. Figure legends must be typed on a separate sheet of paper, and tables must be prepared on individual sheets of paper. Tables and figures must be numbered consecutively in the order cited, figures must have legends with a title and explanatory text, and material shown in a figure must not be duplicated in a table.
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Letters To The Editor

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is not required for Letters To The Editor.
Manuscript Letters To The Editor must not exceed 800 words. Letters To The Editor must be arranged as title page, body, and references. Letters To The Editor may include no more than 1 table or figure.
References References must not exceed 15. References must be numbered in the order cited using superscript Arabic numerals, include only published or in-press literature, cite all authors when there are six or fewer, and list the first six followed by et al. when there are seven or more.
Figures & Tables Letters To The Editor may include no more than 1 table or figure.
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Research Letter

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required for a Research Letter. Abstract must contain 250 words or less. Abstract must be structured. Abstract must use the headings Objective, Study Design, Results, and Conclusion.
Manuscript Manuscript must not exceed 1500 words excluding the title page, references, or legend. Research Letter must comprise a title page, a conflict of interest disclosure, and keywords. Keywords must be included, and if AI-assisted technologies were used, the Acknowledgement section must disclose the AI tool details, how it was used, and that the authors take responsibility for the generated content.
References References must not exceed 15. References must be numbered in the order cited using superscript Arabic numerals, list only published or in-press works, list all authors when there are six or fewer, and list the first six followed by et al. when there are seven or more.
Figures & Tables Research Letter may contain only one table or one figure.
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Guidelines

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required. Abstract must contain 250 words or less. Abstract must be structured. Abstract must use the headings Backgrounds/Aims, Methods, Results, and Conclusions, with no more than 5 keywords provided at the end.
Manuscript Manuscript text must include the sections introduction, materials and methods, results, and discussion. Manuscript must include a title page, abstract, text, acknowledgements, conflict of interest statement, references, tables, and figure legends, and if AI-assisted technologies were used, the Acknowledgement section must name the AI tool, version, manufacturer, dates of use, describe how it was used, and state that the authors take full responsibility for the generated content.
References References must be numbered in the order cited using superscript Arabic numerals in the text, include only published or in-press literature, list all authors when there are six or fewer, and list the first six followed by et al. when there are seven or more.
Figures & Tables Tables must be prepared on individual sheets of paper and figure legends must be typed consecutively on a separate sheet of paper. Tables and figures must be numbered consecutively in the order of appearance in the text, tables must explain all abbreviations and symbols, and figure legends must include a title and enough explanation to be understood without the text.
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Editorials

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must contain 250 words or less. Abstract must be structured. Abstract must include the headings Backgrounds/Aims, Methods, Results, and Conclusions.
Manuscript Editorial must not exceed 1,500 words. Text must include the sections introduction, materials and methods, results, and discussion. Up to 5 keywords must be provided at the end of the abstract, and any use of AI-assisted technologies must be disclosed in the Acknowledgement section with the software details, description of use, and author responsibility statement.
References References must not exceed 20. References must be numbered in the order cited using superscript Arabic numerals, list only published or in-press literature, list all authors when there are six or fewer, and list the first six followed by et al. when there are seven or more.
Figures & Tables Editorials may include 1 table or 1 figure.
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Recent Publications

Immunotherapy and targeted therapy plus hepatic arterial infusion chemotherapy for HCC with portal vein tumor thrombosis (CHANCE2504): a nationwide target trial emulation study

Long-Wang Lin, Qian Chen, Jia-Wei Zhou, Zhen Li, Bin Xiong, Jian-Song Ji, Xiao-Li Zhu, Bin-Yan Zhong, Ming Huang, Jian-Jian Chen, Jin-Ze Li, Hong-Tao Hu, Chang Zhao, Hai-Bin Shi, Zheng-Gang Ren, Hai-Bo Shao, Wei-Zhu Yang, Yang Zhao, Zhi-Cheng Jin, Xue-Feng Kan, Hai-Dong Zhu, Gao-Jun Teng

10.3350/cmh.2026.0693
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Epigenetic and Epitranscriptomic Regulation of Immune Checkpoint Response in Hepatocellular Carcinoma: Mechanisms, Therapeutic Targeting, and Translational Challenges

Yafei Zhi, Yan Guo, Huifang Wei, Michael P. Gantier, Xiwen Ma, Zigang Dong, Kangdong Liu

10.3350/cmh.2026.0745
View Publication

Steatotic liver disease spectrum: From MASLD to MetALD and beyond - Clinical outcomes and precision medicine frontiers

Won Kim

10.3350/cmh.2026.1072
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TLR7 agonist plus anti-PD-L1 enhances HBsAg decline and reinvigorates HBV-specific CD8+ T cells: OCEANcure05 RCT study

Yuying Chen, Ting Wu, Da Huang, Zhize Yuan, Ruiqi Zhai, Bingyao He, Wenyu Wu, Wei Yuan, Peng Wang, Zhongnan Xu, Shuna Wang, Dandan Huo, Meifang Han, Weiming Yan, Di Wu, Qin Ning

10.3350/cmh.2026.0476
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Prevalence of Steatotic Liver Disease Subtypes based on the MetALD-ALD Prediction Index in the United States

Donghee Kim, Pojsakorn Danpanichkul, Karn Wijarnpreecha, Aijaz Ahmed

10.3350/cmh.2026.0954
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Frequently asked questions

How long does it take to publish?

Decisions are available in approximately one month. Fast-track review provides a first decision within 7 days of submission and accepted papers are published within 2 weeks from acceptance.

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What are the publication costs?

Free online access to all published and ahead-of-print articles. Print subscription is free for official members of the Korean Association for the Study of the Liver, and non-members are charged an annual subscription fee.

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Research Topics

Liver Disease Diagnosis and Treatment Hepatitis C virus research Hepatitis B Virus Studies Liver Disease and Transplantation Hepatocellular Carcinoma Treatment and Prognosis Legal and Regulatory Analysis Linguistic, Cultural, and Literary Studies Military Technology and Strategies Alcohol Consumption and Health Effects Diet, Metabolism, and Disease Organ Transplantation Techniques and Outcomes Liver Diseases and Immunity Hepatitis Viruses Studies and Epidemiology Liver physiology and pathology Cholangiocarcinoma and Gallbladder Cancer Studies Diet and metabolism studies Drug-Induced Hepatotoxicity and Protection Diabetes, Cardiovascular Risks, and Lipoproteins Cancer, Hypoxia, and Metabolism Cancer Immunotherapy and Biomarkers Cancer, Lipids, and Metabolism HIV/AIDS drug development and treatment Pediatric Hepatobiliary Diseases and Treatments Gallbladder and Bile Duct Disorders Endoplasmic Reticulum Stress and Disease

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