Overview
Submission Instructions
Recent Publications
Frequently Asked Questions
Research Topics
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Gastroenterology is the flagship journal of the American Gastroenterological Association and publishes clinical, translational, and basic studies across the digestive system, including the liver, pancreas, and nutrition, along with original research, reviews, and perspectives in adult and pediatric gastroenterology and hepatology.
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Subject
Gastroenterology & Hepatology
Impact Factor
25.1
Quartile
Q1
Open Access Type
Hybrid
ISSN
0016-5085
eISSN
1528-0012
Invitation Only
No
Cost Range
Supports open access.
Submission Instructions
Gastroenterology accepts the following article types. Click on an article type to view submission instructions.
Original Articles
Cover Letter
A cover letter should be included with a concise introductory statement and suggested reviewers and associate editor. Cover letter should briefly describe the manuscript, provide relevant contextual information, suggest two to five reviewers with contact details and an associate editor, and explain any deviations from standard format.
Abstract
A structured abstract is required for Original Articles. Abstract must not exceed 260 words. Abstract must be structured. Abstract must use the headings Background and Aims, Methods, Results, Conclusion, and include 4-5 keywords.
Manuscript
Manuscript must not exceed 7,000 words inclusive of main text, references, and table/figure legends. Manuscript must include a title page and a "What You Need to Know" note with the headings BACKGROUND AND CONTEXT, NEW FINDINGS, LIMITATIONS, CLINICAL RESEARCH RELEVANCE, and BASIC RESEARCH RELEVANCE. Manuscript must include 4-5 keywords, a 25-30 word lay summary, a "What You Need to Know" note, a Data Transparency Statement on the title page, and any use of AI in writing must be disclosed before the References under the specified declaration heading.
References
References must be cited with superscript Arabic numerals in order of appearance, include data references for underlying datasets, and end with the phrase "Author names in bold designate shared co-first authorship" with shared first authors shown in bold.
Figures & Tables
Original Articles may include a total of seven tables with no panels and/or figures. Tables may be uploaded separately or included at the end of the manuscript, while figures must be submitted as separate attachments. Figures must be submitted as separate JPEG, TIFF, EPS, or PDF files at 300 PPI resolution.
Brief And Full Reviews
Cover Letter
Cover letter requirements are not explicitly stated for Brief and Full Reviews beyond invited review topic suggestions including a title and short summary. Invited review topic suggestions should include a title and a short summary.
Abstract
Abstract is required. Abstract must not exceed 260 words. Structured abstract is required only if the article type specifically requires it; otherwise the abstract format is not explicitly stated. If a structured abstract is used, it must include Background and Aims, Methods, Results, Conclusions, and Keywords.
Manuscript
Manuscript may be up to 6,000 words. Review articles are limited to a maximum of 4 authors.
References
Review articles may include up to 150 references. References must be cited with superscript Arabic numerals in order of appearance in the text.
Figures & Tables
Review articles may include up to 6 tables and figures. Tables may be uploaded separately or included at the end of the manuscript document, and figures must be submitted as separate attachments with legends at the end of the manuscript body.
Full Length Original Research
Cover Letter
A cover letter should be included with a concise introductory statement, relevant contextual information, suggested reviewers, and the associate editor best qualified to review the paper. Cover letter should include a concise introduction to the manuscript, relevant contextual information, two to five suggested reviewers with email addresses and phone numbers, the suggested associate editor, reasons for any deviations from standard format, and any potential conflicts related to exclusive publication.
Abstract
An abstract is required for full-length original research submissions. Abstract must not exceed 260 words. Structured abstract is required only if applicable, using the headings Background and Aims, Methods, Results, Conclusions, and Keywords. When structured, abstract must include Background and Aims, Methods, Results, Conclusions, and Keywords.
Manuscript
Manuscript must include Materials and Methods in the main text rather than in supplemental material. The manuscript must include a conflict of interest statement, 3–4 keywords if a structured abstract is used, figure and table captions if applicable, and any use of generative AI in writing must be disclosed before the References under the heading "Declaration of Generative AI and AI-assisted technologies in the writing process."
References
References must be cited with superscript Arabic numerals in order of appearance. Reference list should use Index Medicus abbreviations, while personal communications and unpublished data must be cited only in the text and not numbered.
Figures & Tables
Tables may be uploaded separately or placed at the end of the manuscript, while figures must be submitted as separate files and figure legends included at the end of the manuscript body. Full-length original research articles incur charges of $650 for the first printed color figure and $100 for each additional printed color figure, although authors may instead publish color figures online only and black-and-white versions in print at no charge.
Reviews
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract is required. Abstract must not exceed 260 words.
Manuscript
Submission must include manuscript text and a conflict of interest statement, and any use of generative AI or AI-assisted technologies in writing must be disclosed before the References under the heading "Declaration of Generative AI and AI-assisted technologies in the writing process."
References
References must be cited with superscript Arabic numerals in order of appearance in the text.
Figures & Tables
Figures must be submitted as separate attachments, while tables may be uploaded separately or included at the end of the manuscript document. Figures and tables with captions must be included if applicable, and figure legends must appear at the end of the manuscript body.
Reviews In Basic And Clinical Gastroenterology And Hepatology
Cover Letter
A cover letter should be included with a concise introductory statement, and review topic suggestions should include a title and a short summary. The cover letter should concisely describe the manuscript, include relevant contextual information, suggest two to five reviewers with contact details and an associate editor, explain any deviations from standard format, and disclose publication of abstracts or posters.
Abstract
An abstract should be included after the title page. Abstract must not exceed 260 words. Structured abstract is required only if applicable; otherwise the abstract format is not explicitly specified for this article type. If structured, the abstract should use the headings Background and Aims, Methods, Results, Conclusions, and Keywords.
Manuscript
Review articles may be up to 6,000 words. Materials and Methods must be included in the main text and not provided as supplemental information. Keywords should include 3-4 terms separated by semicolons, and any use of generative AI in writing must be disclosed before the References under the heading "Declaration of Generative AI and AI-assisted technologies in the writing process."
References
Review articles may include up to 150 references. References must use superscripted Arabic numerals in order of appearance. References should be numbered by order of appearance, personal communications and unpublished data should be cited only in the text, and journal abbreviations should follow Index Medicus.
Figures & Tables
Review articles may include up to 6 tables and figures. Tables may be uploaded separately or included at the end of the manuscript, while figures must be submitted as separate attachments and figure legends included at the end of the manuscript body. Multiple-panel figures must be submitted as a single attachment with all panels together, and figures must not span more than one journal page.
Research Letters
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract must not be included.
Manuscript
Article text must not exceed 1000 words excluding table or figure legends and references, and up to 1000 additional words of supplemental text may be used only to describe methods. Manuscript must not include section headings such as Methods or Results. Title page must include title, authors' names and institutions, corresponding author contact information, conflict of interest statements for all authors, author contributions, and a statement on whether data, analytic methods, and study materials will be available to other researchers, with location specified if study materials will be shared.
References
References are limited to 10. References must follow the format "Jones RS, et al. Gastroenterology 2011; 2: 373-380" without article titles, list only the first author unless joint first authors are cited, include shared first-author names in bold, and end with the phrase "Author names in bold designate shared co-first authorship."
Figures & Tables
Manuscript may include up to 1 table or figure. Figures must be submitted as separate attachments. Figures may be multi-panel and must be submitted in JPEG, TIFF, EPS, or PDF format at 300 PPI resolution.
Aga Clinical Practice Updates
Cover Letter
Cover Letter requirements are not specified.
Abstract
An abstract should be included after the title page. Abstract must not exceed 260 words. A structured abstract is required only if the article type specifically requires it; otherwise no abstract structure is stated. If a structured abstract is required, it must use the headings Background and Aims, Methods, Results, Conclusions, and Keywords.
Manuscript
Materials and Methods must be included in the main text and not provided as supplemental information. A declaration of generative AI and AI-assisted technologies in the writing process must be placed at the end of the manuscript before the References if such tools were used.
References
References must be cited with superscript Arabic numerals in order of appearance. Reference abbreviations must follow Index Medicus abbreviations, and personal communications or unpublished data must be cited directly in the text without numbering.
Figures & Tables
Tables may be uploaded separately or included at the end of the manuscript document, while figures must be submitted as separate attachments and figure legends included at the end of the manuscript body. Multiple-panel figures must be submitted as a single attachment with all panels together, and figures may not exceed one journal page.
Letters To The Editor
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract is not required for Letters to the Editor.
Manuscript
Letters to the Editor must not exceed 750 words. Letters to the Editor must include a title page with the title, authors’ names, authors’ institutions, corresponding author contact information, and a conflict of interest statement for all authors.
References
Letters to the Editor are limited to 8 references. References must follow the format "Jones RS, et al. Gastroenterology 2011; 2: 373-380," omit the article title, and list only the first author unless joint first authors are cited.
Figures & Tables
Tables and figures are not permitted in Letters to the Editor.
Correspondence
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract requirements are not specified.
Manuscript
Manuscript must not exceed 750 words. Manuscript must include a title page with the title, authors' names, authors' institutions, corresponding author contact information, and a conflict of interest statement for all authors.
References
References are limited to 8. References must follow the format "Jones RS, et al. Gastroenterology 2011; 2: 373-380," omit the article title, and list only the first author unless joint first authors are cited.
Figures & Tables
Figures and tables are not permitted.
Recent Publications
Acute Liver Failure in a Patient with Myasthenia Gravis
Tianzhi Tang, Dhanpat Jain, Peter D. Block
10.1053/j.gastro.2026.05.025
View Publication
PRDM9 Deficiency Drives Mosaic Promoter Deletions in Sporadic Hirschsprung Disease and Supports Blood-based Molecular Stratification
Yun Zhu, Xiaoyu Zuo, Kai Song, Yongxuan Yao, Lihua Huang, Qiuming He, Zipeng Liu, Yi Zheng, Xiaoli Xie, Xinying Zhao, Ye He, Weiyong Zhong, Tuqun Hu, Zhihai Liu, Jiazhang Chen, Shenwei Huang, Xingqiang Lai, Xiaogang Xu, Wei Zhong, Jixiao Zeng, Wenhao Zhou, Huimin Xia, Yan Zhang
10.1053/j.gastro.2026.05.020
View Publication
Impact of Availability of Computer-Aided Detection Devices on Adenoma Detection During Colonoscopy: A Cluster Randomized Study
Jason A. Dominitz, Andrew J. Gawron, Grace B. McKee, Katherine J. Hoggatt, Tonya Kaltenbach
10.1053/j.gastro.2026.05.018
View Publication
A subphenotype of obesity with reduced enteroendocrine GLP-1 synthesis and enhanced tirzepatide response
Alexander L. Ticho, Alison N. McRae, Lizeth Cifuentes, Thomas Fredrick, Diego Anazco, Maria A. Espinosa, Juan M. Garcia Cordova, Michael Romanos, Jose Villamarin, Stephen Johnson, Ryan Lennon, Maria D. Hurtado Andrade, Jun Chen, Michael Camilleri, Andres J. Acosta
10.1053/j.gastro.2026.05.019
View Publication
Upskilling, deskilling, or never skilling – who benefits from AI in colonoscopy??
David Weinberg, Michael Bretthauer
10.1053/j.gastro.2026.05.026
View Publication
Frequently asked questions
How long does it take to publish?
Median 4 days from submission to first decision and median 21 days from acceptance to online publication.
Reformat to Gastroenterology using Livewrite PremiumIs a cover letter required?
A concise cover letter is strongly encouraged. It should describe the manuscript and relevant context, suggest 2-5 reviewers and the associate editor best qualified to review the paper, note any non-preferred editors or reviewers, explain deviations from standard format, and clarify potential conflicts. Fast-track requests should be indicated in the cover letter.
Reformat to Gastroenterology using Livewrite PremiumWhat are the publication costs?
Supports open access.
Reformat to Gastroenterology using Livewrite PremiumResearch Topics
Helicobacter pylori-related gastroenterology studies
Inflammatory Bowel Disease
Liver Disease Diagnosis and Treatment
Microscopic Colitis
Eosinophilic Esophagitis
Gastrointestinal motility and disorders
Gastroesophageal reflux and treatments
Gastric Cancer Management and Outcomes
Pancreatitis Pathology and Treatment
Esophageal and GI Pathology
Pancreatic and Hepatic Oncology Research
Colorectal Cancer Screening and Detection
Liver Disease and Transplantation
Diet and metabolism studies
Gastrointestinal disorders and treatments
Hepatitis C virus research
Esophageal Cancer Research and Treatment
Digestive system and related health
Genetic factors in colorectal cancer
Clinical Nutrition and Gastroenterology
Diverticular Disease and Complications
Celiac Disease Research and Management
Hepatitis B Virus Studies
Liver Diseases and Immunity
Gut microbiota and health