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Clinical and Translational Medicine

Clinical and Translational Medicine is an open access journal focused on accelerating the translation of preclinical research to clinical application and communication between basic and clinical scientists. It emphasizes a bench-to-bedside approach and welcomes submissions from clinicians, researchers, policy makers, and industry across areas of clinical and translational medicine, with themed topics including clinical bioinformatics, clinical trans-omics, single-cell biomedicine, stem cell biology and therapy, clinical genomics, vaccines and immunotherapy, and chronic metabolic diseases.

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Subject Medicine, Research & Experimental, Oncology
Impact Factor 6.8
Quartile Q1
Open Access Type Open
ISSN 2001-1326
eISSN 2001-1326
Invitation Only No
Cost Range Open access article publication charge (APC) applies; institutional or funder payment may cover the APC.

Submission Instructions

Clinical and Translational Medicine accepts the following article types. Click on an article type to view submission instructions.

Original Research Article

Cover Letter A cover letter is required. Cover letter must explain why the manuscript should be published, address any journal policy issues, declare any potential competing interests, confirm all authors approved the submission, confirm the content has not been published or submitted elsewhere, and name the special issue if applicable.
Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be structured. Abstract must include the headings Background, Methods, Results, and Conclusions.
Manuscript Manuscript must include Background, Methods, Results, Discussion, and Conclusions sections. Manuscript must include 3 to 10 keywords, a Declarations section with the subheadings Ethics approval and consent to participate, Consent for publication, Data availability statement, Conflict of interest, and Funding, and abbreviations must be defined at first use with a list provided as needed.
References References must be numbered consecutively in order of appearance and cited in the text using consecutive Arabic superscript numerals.
Figures & Tables Figures must be submitted as separate files, while tables must appear in the main text file. Tables and figure legends must be concise, self-contained, and define all abbreviations, symbols, and units needed for understanding.
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Review Article

Cover Letter A cover letter is required. Cover letter must explain why the manuscript should be published, address any journal policy issues, declare potential competing interests, confirm all authors approved the submission, confirm the content has not been published or submitted elsewhere, and name the special issue if applicable.
Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be structured. Abstract must include background, main body of the abstract, and short conclusion.
Manuscript Manuscript must not exceed 6000 words excluding references, figures, and tables. Manuscript must include Background, Main text, and Conclusions sections. Manuscript must include 3 to 10 keywords and, if abbreviations are used, they must be defined at first use and a list of abbreviations must be provided.
References References must not exceed 100 cited publications. References must be numbered consecutively in order of appearance and cited in the text using consecutive Arabic superscript numerals.
Figures & Tables Manuscript must not exceed 10 figures. Main text and figures must be submitted as separate files, and appendices must also be supplied as separate files if relevant. Tables must be editable and self-contained with concise legends and defined abbreviations, and figure legends must be concise and define all symbols, abbreviations, and units.
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Invited Letter

Cover Letter A cover letter is required. Cover letter must explain why the manuscript should be published, address any journal policy issues, declare any potential competing interests, confirm all authors approved the submission, confirm the content has not been published or submitted elsewhere, and name the special issue if applicable.
Abstract Abstract is not required. Abstract must not exceed 300 words if included. Abstract does not require a structured format because section titles such as Abstract are not required. Section titles such as Abstract and Keywords are not required.
Manuscript Manuscript must not exceed 1000 words excluding references, figures, and tables. Section titles such as Abstract, Keywords, and Conclusions are not required. Manuscript must include a Declarations section with the subheadings Ethics approval and consent to participate, Consent for publication, Data availability statement, Conflict of interest, and Funding.
References References must not exceed 10 cited publications. References must be numbered consecutively in order of appearance and cited in the text using consecutive Arabic superscript numerals.
Figures & Tables Figures must be submitted separately from the main text file, and tables are included after the references in the main text file.
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Short Communication

Cover Letter A cover letter is required. Cover letter must explain why the manuscript should be published, address any journal policy issues, declare potential competing interests, and confirm that all authors approved the submission.
Abstract Abstract must not be included.
Manuscript Manuscript must not exceed 2000 words excluding references, figures, and tables. Main text must have no section titles such as abstract, background, methods, results, or discussion and must end with a clear conclusion. Manuscript must include a Declarations section with the subheadings Ethics approval and consent to participate, Consent for publication, Data availability statement, Conflict of interest, and Funding.
References References must not exceed 25 cited publications. References must be numbered consecutively in order of appearance and cited in the text using Arabic superscript numerals.
Figures & Tables Figures and tables must not exceed a combined total of 3. Main text, figures, and supporting information must be submitted as separate files.
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Letter To The Journal

Cover Letter A cover letter is required. Cover letter must explain why the manuscript should be published, explain any issues relating to journal policies, declare any potential competing interests, confirm all authors approved the submission, confirm the content has not been published or submitted elsewhere, and name the special issue if applicable.
Abstract Abstract must not be included.
Manuscript Manuscript must not exceed 1000 words excluding references, figures, and tables. Main text must end with a clear conclusion and must not use section titles such as abstract, background, methods, results, or discussion. Manuscript must include a Declarations section.
References References must not exceed 10 cited publications. References must be numbered consecutively in order of appearance and cited in the text using consecutive Arabic superscript numerals.
Figures & Tables Figures and tables together must not exceed 2. Main text and figures must be submitted as separate files.
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Recent Publications

Pattools‑implemented methylation vector analysis reveals aberrant subtype‑specific methylation in lung cancer across tissue and plasma cfDNA

Zehua Dong, Yifeng Luo, Tingting Hu, Yihang Cheng, Qiaoling Ren, Li Xu, Yuan Tan, Wei Li, Yaoxiang Sun, Mingzhi Chen, Zhonghua Shen, Bin Zhang, Youhuang Bai, Yue Tao, Zhihong Cao, Deqiang Sun

10.1002/ctm2.70812
View Publication

PRAME promotes invasion and metastasis of salivary adenoid cystic carcinoma by regulating RARα stability via the cullin2 ubiquitin‐proteasome system

Xudong Wang, Tingyao Ma, Yixin Jing, Tianyi Li, Xi Zhao, Guohan Zhao, Ran Gao, Lu Kong, Xiaohong Chen

10.1002/ctm2.70787
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Overcoming the cytosine base editing barrier: Virus‐like particles with uracil‐DNA glycosylase inhibition unlocking the clinical potential

Yuqing Wu, Xingyu Zhu, Junjie Zhu, Jia Chen, Jiaxu Hong

10.1002/ctm2.70803
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NSUN4‐dependent m5C modification facilitates mitochondrial fission to accelerate diabetic nephropathy process via regulating SMURF1/CAMK1 axis

Danyi Yang, Yinyin Chen, Hao Li, Guoyong Liu, Yang Gao, Liyu He

10.1002/ctm2.70783
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Venetoclax for elderly patients with acute myeloid leukaemia unfit for intensive chemotherapy: Prospects, resistance mechanisms and management strategies

Jinlin Zhang, Jile Liu, Mohan Zhao, Xiaoyu Zhang, Linlin Liu, Mengnan Li, Changze Cao, Rui Zhang, Mingfeng Zhao

10.1002/ctm2.70797
View Publication

Frequently asked questions

How long does it take to publish?

Submission to first decision (median): 7 days; submission to acceptance (median): 105 days; acceptance to publication (median): 15 days.

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Is a cover letter required?

A cover letter is required. It must explain why the manuscript should be published in Clinical and Translational Medicine, address any issues relating to journal policies, declare potential competing interests, confirm all authors approved the submission, confirm the work has not been published or submitted elsewhere, and name the special issue if applicable.

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What are the publication costs?

Open access article publication charge (APC) applies; institutional or funder payment may cover the APC.

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Research Topics

Cancer Immunotherapy and Biomarkers Single-cell and spatial transcriptomics Ferroptosis and cancer prognosis RNA modifications and cancer Cancer Genomics and Diagnostics Immune cells in cancer Cancer-related molecular mechanisms research Epigenetics and DNA Methylation Cancer Cells and Metastasis MicroRNA in disease regulation Extracellular vesicles in disease Cancer, Hypoxia, and Metabolism Immune Cell Function and Interaction COVID-19 Clinical Research Studies CAR-T cell therapy research Circular RNAs in diseases Immunotherapy and Immune Responses Gut microbiota and health Cancer-related gene regulation Ubiquitin and proteasome pathways SARS-CoV-2 and COVID-19 Research Inflammasome and immune disorders Lung Cancer Treatments and Mutations interferon and immune responses RNA Research and Splicing

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