Overview
Submission Instructions
Recent Publications
Frequently Asked Questions
Research Topics
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CM
Clinical Medicine is a peer-reviewed journal of the Royal College of Physicians that publishes advances in general and specialist medicine, authoritative reviews, original research, guideline summaries, and clinically focused reviews, with a dedicated CME section and six issues per year. From January 1, 2024, it operates as a full gold open access journal, with accepted articles published online ahead of each issue.
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Subject
Medicine, General & Internal
Impact Factor
3.9
Quartile
Q1
Open Access Type
Open
ISSN
1470-2118
eISSN
1473-4893
Invitation Only
No
Cost Range
Article Publishing Charge: USD 2500 for Full Length Articles and Reviews; USD 1250 for Short Articles and Case Reports; paying members and fellows of the Royal College of Physicians who are named authors are eligible for a 100% discount.
Submission Instructions
Clinical Medicine accepts the following article types. Click on an article type to view submission instructions.
Full Length Articles (Original Research)
Cover Letter
A cover letter must be included with the submission. The cover letter must confirm approval for publication by all authors and by the responsible authorities where the work was carried out.
Abstract
A structured abstract is required. Abstract must be 250 words. Abstract must be structured. Abstract headings must be Study Objective, Design, Setting, Participants, Interventions, Main Outcome Measure(s), Results, and Conclusions.
Manuscript
Main text must be up to 3,000 words excluding tables, figure legends, and references. Manuscript must include, in order, Title Page, Structured Abstract and Keywords, Introduction, Materials and Methods, Results, Discussion, and References. Manuscript must include keywords, mandatory highlights submitted separately as 3 to 5 bullet points, a mandatory graphical abstract submitted separately, an AI disclosure section before the references if generative AI was used in manuscript preparation, and explicit study limitations.
References
References are limited to 30. References must follow AMA style. References must be cited by numbers in square brackets and listed in the order of appearance, and AMA references with one to six authors list all authors while those with seven or more list the first three followed by et al.
Figures & Tables
A maximum of 4 figures and/or tables is allowed. Figures, tables, and the graphical abstract must be submitted as separate files rather than embedded only in the manuscript. Figures and tables must be numbered in numerical order, all legends or captions must be included in the manuscript, figures require relevant captions, and tables must be editable and include titles, descriptions, and footnotes.
Review
Cover Letter
A cover letter is required.
Abstract
An abstract is required. Abstract must be up to 150 words.
Manuscript
Manuscript must be up to 3,000 words. Review must address a question relevant to a general medical audience. Manuscript must include a box summarising key practice implications, mandatory highlights, up to 6 keywords after the abstract, a declaration of generative AI use before the references if applicable, and a graphical abstract submitted as a separate file.
References
Reference list may include up to 50 references. AMA style is required. References must be cited in numerical order in the text and listed in the same order, with one to six authors listed in full and seven or more shortened after the third author with et al.
Figures & Tables
A total of up to 4 figures and or tables is allowed. Figures must be uploaded as separate files, high-resolution artwork must not be included in the Word manuscript, captions must be included in the manuscript, and the graphical abstract must be submitted as a separate file. Figures and tables must be numbered and cited in numerical order in the text, figures must include captions, and tables must include titles, descriptions, footnotes, and editable text format.
Narrative Reviews
Cover Letter
A cover letter is required. The cover letter must confirm approval for publication by all authors and by the responsible authorities where the work was carried out.
Abstract
An abstract is required. Abstract must be up to 150 words. Abstract must be unstructured.
Manuscript
Manuscript must be up to 3,000 words. Manuscript must address a question relevant to a general medical audience and include a box summarising key practice implications. The submission must include highlights, 3 to 8 keywords, a competing interests statement, an AI-use disclosure section before the references if generative AI was used in manuscript preparation, and a mandatory graphical abstract submitted as a separate file.
References
References may include up to 50 entries. References must follow AMA style. References must be cited in the text by numbers in square brackets and listed in numerical order of first appearance, with all authors listed for one to six authors and the first three authors followed by et al for seven or more authors.
Figures & Tables
The article may include up to 4 figures and or tables. Figures, tables, and the graphical abstract must be uploaded as separate files rather than embedded in the manuscript. All figures and tables must have captions or legends and be cited in the text in numerical order, and tables must be provided in editable text format.
Systematic Reviews
Cover Letter
A cover letter is required.
Abstract
An abstract is required. Abstract must be no more than 150 words.
Manuscript
Manuscript must be no more than 3,000 words. Manuscript must address a question relevant to a general medical audience. Manuscript must include a box summarising key practice implications, highlights, up to 6 keywords, an AI disclosure section before the references if generative AI was used in manuscript preparation, and a graphical abstract submitted as a separate file.
References
References must not exceed 50. References must follow AMA style. References must be cited in the text by numbers in square brackets and listed in the order of appearance, with all authors listed for one to six authors and the fourth and subsequent authors replaced by et al for seven or more authors.
Figures & Tables
A maximum of 4 figures and or tables is permitted. Figures must be submitted as separate files, legends or captions for all figures and tables must be included in the manuscript, and high-resolution artwork must not be included in the Word document. All figures and tables must be numbered and cited in numerical order in the text, figures must include relevant captions, and tables must include titles, descriptions, and footnotes.
Quality Improvement
Cover Letter
A cover letter is required. Publication must be approved by all authors.
Abstract
An abstract is required. Abstract must be no more than 150 words.
Manuscript
Manuscript must be no more than 1,500 words. Manuscript must describe and evaluate a healthcare process or system improvement intervention, outline how the quality improvement programme was set up, report measurable benefits and lessons learnt, follow SQUIRE guidelines, and explicitly include study limitations. Highlights are mandatory and must be provided as 3 to 5 bullet points in a separate editable file, authors must provide 3 to 8 keywords, and any use of generative AI in manuscript preparation must be disclosed in a section placed before the references.
References
References may include up to 15 sources. AMA style is required. References must be cited in the text by numbers in square brackets and listed in numerical order of appearance, with all authors listed for one to six authors and the first three authors followed by et al for seven or more authors.
Figures & Tables
Figures must be submitted as separate files rather than included in the manuscript, while tables must be provided in editable text format. Figures and tables must be numbered in the order cited in the text, figures must include captions, and tables must include titles, descriptions, footnotes, and legends or captions in the manuscript.
Case Reports
Cover Letter
A cover letter is required. Cover letter content is not explicitly specified.
Abstract
A concise and factual abstract is required.
Manuscript
Articles must be divided into clearly defined and numbered sections. The manuscript must include highlights in a separate editable file with 3 to 5 bullet points, 3 to 8 keywords, and an AI disclosure section before the references if generative AI was used in manuscript preparation.
References
AMA reference style is required. References must be cited in the text by numbers in square brackets and listed in the order of first appearance, with up to 6 authors listed and 7 or more shortened after the third author with et al.
Figures & Tables
Figures must be uploaded as separate files, while figure and table legends or captions must be included in the manuscript. All figures and tables must be cited in the text in numerical order, figures must include relevant captions, and tables must include titles, descriptions, and footnotes.
Acute Medical Care (Amc)
Cover Letter
Cover letter is required.
Abstract
Abstract is required. Abstract must be no more than 150 words.
Manuscript
Manuscript must be 1,000 words. Manuscript must use a case-based discussion format with sections for Case presentation, Diagnosis, Initial management and prognosis, Case progression and outcome, and Discussion. Manuscript must include 4 to 6 key learning points, keywords, highlights, a competing interests statement, an AI disclosure section before the references if generative AI was used in preparation, and a statement of written informed consent.
References
References are limited to 5. AMA style is required. References must be cited numerically in the text and listed in the order of appearance, with all authors listed for one to six authors and the first three authors followed by et al for seven or more authors.
Figures & Tables
A maximum of 1 figure and/or table is permitted. Figures must be uploaded as separate files, while legends or captions for figures and tables must be included in the manuscript. Figures and tables must be numbered in numerical order and cited in the text, with tables submitted in editable format rather than as images.
Lessons Of The Month
Cover Letter
A cover letter must be included with the submission.
Abstract
An abstract is required. Abstract must be no more than 150 words.
Manuscript
Manuscript must be no more than 1,000 words. The manuscript must include keywords, mandatory highlights of 3 to 5 bullet points, and an AI disclosure statement before the references if generative AI was used in manuscript preparation.
References
References are limited to a maximum of 10. AMA style is required. References must be cited in the text using numbers in square brackets and listed in numerical order of appearance, with AMA author listing of all authors for one to six authors and et al for seven or more authors.
Figures & Tables
A maximum of 4 figures and/or tables may be included. Figures must be uploaded as separate files rather than embedded in the manuscript, and legends or captions for all figures and tables must be included in the manuscript. Figures and tables must be numbered in the order cited in the text, figures must include captions, and tables must include titles, descriptions, and footnotes.
Letters To The Editor
Cover Letter
A cover letter must be included.
Abstract
Abstract must not be included.
Manuscript
Manuscript must be up to 350 words. Keywords and highlights are required, and any use of generative AI in manuscript preparation must be disclosed in a new section before the references list.
References
References may include up to 5 items. AMA style is required. References must be cited in the text by numbers in square brackets and listed in the order of appearance, with all authors listed for one to six authors and the fourth and subsequent authors replaced by et al for seven or more authors.
Figures & Tables
Figures and tables must not be included.
Concise Guidance
Cover Letter
A cover letter is required.
Abstract
An abstract is required. Abstract must be no more than 150 words.
Manuscript
Manuscript must be no more than 3,000 words. Manuscript must be organized as a sequence of subheadings related to the clinical questions addressed and include an explicit link to the guideline, the scope as it relates to general medical practice and disease burden, what is out of scope where relevant, and a conclusion focusing on what is new with health economics and research recommendations highlighted where relevant. Manuscript must include a box summarising key practice implications from the guideline, mandatory highlights, up to 6 keywords after the abstract, and an AI disclosure section before the references if generative AI was used in manuscript preparation.
References
References may include up to 50 entries. References must use AMA style. References must be cited by number in square brackets and listed in the order of appearance, with all authors listed for one to six authors and the fourth and subsequent authors replaced by et al for seven or more authors.
Figures & Tables
Figures must be submitted as separate files rather than embedded in the manuscript, while legends or captions for all figures and tables must be included in the manuscript. Figures and tables must be numbered in the order cited in the text, figures must include relevant captions, and tables must include titles, descriptions, footnotes, and be submitted as editable text.
Recent Publications
Frailty Phenotype, Genetic Risk, and Long-Term Incident Systemic Lupus Erythematosus Risk: Insights from the UK Biobank Study Integrated with Multi-Omics Analysis
Peizhi Deng, Siyu Yan, Jianyun Lu
10.1016/j.clinme.2026.100598
View Publication
Hypertension: a common, yet poorly managed condition. What can we do better?
Abilash Sathyanarayanan, Indranil Dasgupta, Ponnusamy Saravanan
10.1016/j.clinme.2026.100604
View Publication
The impact of primary percutaneous coronary intervention timing on prognosis in STEMI patients
Lihui Zhou, Jin Si, Ming Yi, Keling Xiao, Lijie Sun, Haoyu Zhang, Jinghao Sun, Zhenxing Fan, Zhi Liu, Jing Gao, Lin Pi, Yinghua Zhang, Jing Li
10.1016/j.clinme.2026.100602
View Publication
Wearable devices in the management of hypertension: Navigating the intersection between digital advancement and evidence-based practice
Abubaker Eltayeb, Ayesha Ahmed, Ajay Gupta
10.1016/j.clinme.2026.100595
View Publication
Age, sex and ethnicity changes in creatine kinase and sex- and ethnicity-specific reference intervals of creatine kinase
Tejas Kalaria, Rousseau Gama, Emma Tuddenham, Catherine Collingwood, Hem Sapkota, Latika Gupta, Mariam El Hawli, Rachel L Griffiths
10.1016/j.clinme.2026.100596
View Publication
Frequently asked questions
How long does it take to publish?
Proof corrections are requested within two days after acceptance.
Reformat to Clinical Medicine using Livewrite PremiumIs a cover letter required?
A cover letter is included in the submission checklist. CME submissions should include three possible self-assessment questions in the cover letter.
Reformat to Clinical Medicine using Livewrite PremiumWhat are the publication costs?
Article Publishing Charge: USD 2500 for Full Length Articles and Reviews; USD 1250 for Short Articles and Case Reports; paying members and fellows of the Royal College of Physicians who are named authors are eligible for a 100% discount.
Reformat to Clinical Medicine using Livewrite PremiumResearch Topics
Primary Care and Health Outcomes
Innovations in Medical Education
Palliative Care and End-of-Life Issues
Healthcare cost, quality, practices
Respiratory Support and Mechanisms
Emergency and Acute Care Studies
Venous Thromboembolism Diagnosis and Management
Healthcare Policy and Management
Liver Disease Diagnosis and Treatment
Sepsis Diagnosis and Treatment
Acute Ischemic Stroke Management
Cardiac, Anesthesia and Surgical Outcomes
Health Systems, Economic Evaluations, Quality of Life
Clinical practice guidelines implementation
Global Health Workforce Issues
Healthcare Quality and Management
Medical Research and Treatments
Health and Medical Research Impacts
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Clinical Reasoning and Diagnostic Skills
Frailty in Older Adults
Cardiac Imaging and Diagnostics
Diabetes Management and Research
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Atrial Fibrillation Management and Outcomes