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Clinical Pharmacokinetics

Clinical Pharmacokinetics is a major review journal in the area of clinical pharmacokinetics, the study of drug disposition in the human body, with a focus on drug development, rational pharmacotherapy, clinical pharmacokinetics and pharmacodynamics, and postgraduate education in clinical pharmacology and therapeutics.

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Subject Pharmacology & Pharmacy
Impact Factor 4
Quartile Q1
Open Access Type Hybrid
ISSN 0312-5963
eISSN 1179-1926
Invitation Only No
Cost Range Open access APC: £3190.00 GBP / $5190.00 USD / €3990.00 EUR; subscription publishing model has no APC charges.

Submission Instructions

Clinical Pharmacokinetics accepts the following article types. Click on an article type to view submission instructions.

Review Article

Cover Letter The corresponding author must mention any unpublished material included in the manuscript and provide transparency on re-use of material in a cover letter to the Editor.
Abstract required The abstract must be 150 to 250 words. unstructured
Manuscript Review Article submissions must be up to 8000 words, excluding the abstract, references, figure legends, and table captions. A disclosure statement is required, and the manuscript must include a statement identifying who had the idea for the article, who performed the literature search and data analysis, and who drafted or critically revised the work.
References Reference citations in the text must use numbers in square brackets. The reference list must include only works cited in the text that are published or accepted for publication, entries must be numbered consecutively, and DOI links should be included when available.
Figures & Tables Figures should be submitted within the body of the text, and large figures may be submitted separately only if the manuscript file size causes upload problems. All tables and figures must be numbered using Arabic numerals, cited in text in consecutive order, and figures and tables must include captions and identify any previously published material by reference.
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Systematic Review

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. The abstract must be 150 to 250 words, and it may be increased to up to 450 words if needed for compliance with reporting guidelines.
Manuscript Systematic Review manuscripts are limited to up to 10,000 words. Systematic Reviews must follow PRISMA. A Declarations section is required, and if the systematic review is registered the registration number must appear in the methods section and at the end of the abstract.
References Reference citations must use numbers in square brackets. The reference list must include only cited works that have been published or accepted for publication, be numbered consecutively, and include full DOI links when available.
Figures & Tables Figures should be submitted within the body of the text, and large figures may be submitted separately if the manuscript file causes upload problems. Tables and figures must be numbered in Arabic numerals, cited in consecutive order, and given concise captions with source references for previously published material.
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Original Research

Cover Letter A cover letter is required. The corresponding author must disclose preprint posting details including DOI and licensing terms, mention any unpublished material included in the manuscript, and request exceptions to suggested symbology if needed.
Abstract An abstract is required. The abstract must be 150 to 250 words and may be increased to up to 450 words if the topic dictates and to allow full compliance with the relevant reporting guidelines. The abstract must be structured. The abstract must include the drug name or names studied, the route of administration, the population studied, and the results of the primary objective and major clinical pharmacokinetic findings.
Manuscript The manuscript must be up to 6000 words. Section and subsection headings must use decimal numbering, and titles and subtitles must describe the intervention, methodology, or setting rather than the study results. The manuscript must include a Data Availability Statement, a disclosure statement, and a Declarations section.
References Reference citations in the text must use numbers in square brackets. References must be numbered consecutively, include only works cited in the text that are published or accepted, and include full DOI links when available.
Figures & Tables Figures should be submitted within the body of the text, while large figures may be submitted separately if the manuscript file size causes upload problems. Tables must be numbered with Arabic numerals and cited in order, figures must be numbered with Arabic numerals and cited in order, and each must have a concise caption with previously published material identified by a reference.
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Letter To The Editor

Cover Letter The corresponding author must mention any unpublished material included in the manuscript and provide transparency on re-use of material in the cover letter.
Abstract required 150 to 250 words. unstructured.
Manuscript The manuscript must use numbered decimal headings with no more than three levels and include sections from Introduction to Conclusions. A section entitled Declarations must be included, and if applicable it must contain subsections for Funding, Conflicts of Interest, Availability of data and material, Consent to participate, Consent for publication, Code availability, and Author contributions.
References Numbered citations in square brackets. Reference list entries must be numbered consecutively, include only cited works that are published or accepted for publication, and include full DOI links when available.
Figures & Tables Figures should be submitted within the body of the text, and large figures may be submitted separately only if the manuscript file size causes upload problems. Tables must be numbered with Arabic numerals and cited in consecutive order, figures must be numbered with Arabic numerals and cited in consecutive order, and figure and table captions must identify previously published material with a reference source.
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Recent Publications

A Model-Informed Early Prediction of Methotrexate-Induced Acute Kidney Injury in Pediatric Patients with Osteosarcoma Using Real-World Data: A Multi-center Pharmacokinetic Study

Patricia Rega, Jorge Morales Vallespin, Azucena Aldaz, Andrew Pappas, Paulo Caceres Guido, Manuel Azocar, Milena Villarroel, Jennifer L. Pauley, Clinton F. Stewart, Manuel Ibarra, Paula Schaiquevich

10.1007/s40262-026-01658-w
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Collecting Metabolite Pharmacokinetics in Drug–Drug Interaction Studies: A Review of Industry Practices and Data Utilization

Tatyana Dubich, Thijs van Iersel, Kamelia Mirdamadi, Ewoud-Jan van Hoogdalem

10.1007/s40262-026-01657-x
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Renal or Hepatic Impairment Does Not Affect Pharmacokinetics, Safety, or Tolerability of Subcutaneous Cagrilintide

Mette J. F. Nielsen, Niels-Peter Becker, Helene H. Hansen Duus, Katrine Kirkeby, Viera Kupčová, Britt W. Lauenborg, Benjamin Low, Olivia Svolgaard, Louise Witten

10.1007/s40262-026-01654-0
View Publication

Vutrisiran-Mediated Knockdown of Transthyretin in Patients with ATTR Amyloidosis

Marianna Fontana, Vincent Algalarrondo, Pablo Garcia-Pavia, Mathew S. Maurer, Julian D. Gillmore, Francesco Cappelli, Kiranmai Kolachana, Xiuqing Gao, Satyawan Jadhav, Nitin Mehrotra, Gabriel Robbie, Prajakta Badri

10.1007/s40262-026-01651-3
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Population Pharmacokinetic Analysis of Glecaprevir and Pibrentasvir in Pediatric Patients ≥ 3 to < 18 Years of Age with Genotypes 1–6 Chronic Hepatitis C Virus (HCV) Infection

Neha Thakre, Denise Beck, Ahmed M. Saeed, Doerthe Eckert, Mong-Jen Chen, Wei Liu, Hoi Kei Lon, Nael M. Mostafa, Sven Mensing

10.1007/s40262-026-01637-1
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Frequently asked questions

How long does it take to publish?

Initial editorial appraisal is followed by external peer review. Most manuscripts require revision before acceptance. The article is published online after receipt of corrected proofs.

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Is a cover letter required?

A cover letter is expected for manuscript submission when documenting unpublished material and re-use of material, and the corresponding author manages submission communication.

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What are the publication costs?

Open access articles require an APC of £3190.00 GBP / $5190.00 USD / €3990.00 EUR, determined at acceptance. Subscription publishing is available with no APC charges.

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Research Topics

Pharmacogenetics and Drug Metabolism Antibiotics Pharmacokinetics and Efficacy Pharmacological Effects and Toxicity Studies Drug Transport and Resistance Mechanisms Pharmaceutical studies and practices Epilepsy research and treatment HIV/AIDS drug development and treatment Anesthesia and Sedative Agents Statistical Methods in Clinical Trials Analytical Methods in Pharmaceuticals Renal Transplantation Outcomes and Treatments Diabetes Treatment and Management Cancer Treatment and Pharmacology Drug-Induced Hepatotoxicity and Protection Antibiotic Resistance in Bacteria Computational Drug Discovery Methods Pharmacology and Obesity Treatment Pneumonia and Respiratory Infections Pain Management and Opioid Use Biosimilars and Bioanalytical Methods Pregnancy and Medication Impact Atrial Fibrillation Management and Outcomes Monoclonal and Polyclonal Antibodies Research Treatment of Major Depression Schizophrenia research and treatment

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